Sucralfate promotes healing of duodenal ulcer by:
A. Enhancing gastric mucus and bicarbonate
secretion
B. Coating the ulcer and preventing the action
of acid-pepsin on ulcer base
C. Promoting regeneration of mucosa
D. Both ‘A’ and ‘B’ are correct

1 Answer

Answer :

B. Coating the ulcer and preventing the action
of acid-pepsin on ulcer base

Related questions

Description : The primary mechanism by which prostaglandins promote ulcer healing is: A. Inhibition of gastric acid secretion B. Augmentation of bicarbonate buffered mucus layer covering gastroduodenal mucosa C. Increased bicarbonate secretion in gastric juice D. Increased turnover of gastric mucosal cell

Last Answer : B. Augmentation of bicarbonate buffered mucus layer covering gastroduodenal mucosa

Description : Choose the antiulcer drug that inhibits gastric acid secretion, stimulates gastric mucus and bicarbonate secretion and has cytoprotective action on gastric mucosa: A. Misoprostol B. Sucralfate C. Carbenoxolone sodium D. Colloidal bismuth subcitrate

Last Answer : A. Misoprostol

Description : Choose the correct statement about H2 receptor blockers: A. They are the most efficacious drugs in inhibiting gastric acid secretion B. They cause fastest healing of duodenal ulcers C. They prevent stress ulcers in the stomach D. They afford most prompt relief of ulcer pain

Last Answer : C. They prevent stress ulcers in the stomach

Description : The preferred regimen for preventing duodenal ulcer relapse is: A. Maintenance antacid regimen B. Maintenance H2 blocker regimen C. On demand intermittent H2 blocker regimen D. Maintenance sucralfate regimen

Last Answer : B. Maintenance H2 blocker regimen

Description : The most important drawback of sucralfate in the treatment of duodenal ulcer is: A. Low ulcer healing efficacy B. Poor relief of ulcer pain C. High incidence of side effects D. Need for taking a big tablet four times a day

Last Answer : D. Need for taking a big tablet four times a day

Description : What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor? (a) In the absence of HCl secretion, inactive pepsinogen is not converted into the active ... c) Gastric juice will be deficient in chymosin. (d) Gastric juice will be deficient in pepsinogen.

Last Answer : (a) In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.

Description : The following statement is true about misoprostol: A. It relieves peptic ulcer pain, but does not promote ulcer healing B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding ... side effects than H2 blockers D. It is the most effective drug for preventing ulcer relapse

Last Answer : B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers

Description : What is true of acid control therapy with H2 blockers: A. It generally heals duodenal ulcers faster than gastric ulcers B. It checks bleeding in case of bleeding peptic ulcer C. It prevents gastroesophageal reflux D. Both ‘A’ and ‘B’ are correct

Last Answer : A. It generally heals duodenal ulcers faster than gastric ulcers

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Description : Compared to H2 blockers, omeprazole affords the following: A. Faster relief of ulcer pain B. Faster healing of duodenal ulcer C. Higher efficacy in healing reflux esophagitis D. All of the above

Last Answer : D. All of the above

Description : For healing duodenal ulcer the usual duration of H2 blocker therapy is: A. 4 weeks B. 6 weeks C. 8 weeks D. 12 weeks

Last Answer : C. 8 weeks

Description : When gastric analysis testing reveals excess secretion of gastric acid, which of the following diagnoses is supported? a) Duodenal ulcer Patients with duodenal ulcers usually secrete an excess ... anemia Patients with pernicious anemia secrete no acid under basal conditions or after stimulation.

Last Answer : a) Duodenal ulcer Patients with duodenal ulcers usually secrete an excess amount of hydrochloric acid.

Description : The following antiulcer drug does not act by reducing the secretion of or neutralizing gastric acid: A. Magaldrate B. Sucralfate C. Misoprostol D. Omeprazol

Last Answer : B. Sucralfate

Description : Eradication of H.pylori along with gastric antisecretory drugs affords the following benefit(s): A. Faster relief of ulcer pain B. Faster ulcer healing C. Reduced chance of ulcer relapse D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Description : In peptic ulcer, antacids are now primarily used for: A. Prompt pain relief B. Ulcer healing C. Preventing ulcer relapse D. Control of bleeding from the ulcer

Last Answer : A. Prompt pain relief

Description : The primary mechanism of action of the combined estrogen-progestin oral contraceptive pill is: A. Production of cervical mucus hostile to sperm penetration B. Suppression of FSH and ... Making endometrium unsuitable for implantation D. Enhancing uterine contractions to dislodge the fertilized ovum

Last Answer : B. Suppression of FSH and LH release

Description : ntacids administered concurrently reduce efficacy of the following antipeptic ulcer drug: A. Cimetidine B. Colloidal bismuth C. Sucralfate D. Pirenzepine

Last Answer : C. Sucralfate

Description : The nurse recognizes that the patient with a duodenal ulcer will likely experience a) pain 2-3 hours after a meal. The patient with a gastric ulcer often awakens between 1-2 A.M. with pain ... patient with gastric ulcer. d) weight loss. The patient with a duodenal ulcer may experience weight gain.

Last Answer : a) pain 2-3 hours after a meal. The patient with a gastric ulcer often awakens between 1-2 A.M. with pain and ingestion of food brings relief.

Description : Which of the following statement(s) is/are true concerning pharmacologic agents used to accelerate wound healing? a. A number of these agents are now currently approved for use in ... healing in chronic wounds d. Growth hormone functions by promoting fibroblast proliferation and collagen synthesis

Last Answer : Answer: b, c Currently there are no approved clinical agents that accelerate normal healing. Although a number of clinical trials are in progress, no agents are currently ... hormone administration significantly accelerates donor site healing, presumably due to its effects in minimizing catabolism

Description : Select the drug which is an inhibitor of gastric mucosal proton pump: A. Carbenoxolone sodium B. Sucralfate C. Famotidine D. Lansoprazole

Last Answer : D. Lansoprazole

Description : As an antacid, sodium bicarbonate has the following disadvantages except: A. It causes acid rebound B. In ulcer patients, it increases risk of perforation C. It has low acid neutralizing capacity D. It is contraindicated in hypertensives

Last Answer : C. It has low acid neutralizing capacity

Description : Choose the correct statement about colloidal bismuth subcitrate: A. It causes prolonged neutralization of gastric acid B. It has anti-H.pylori activity C. It relieves peptic ulcer pain promptly D. All of the above are correct

Last Answer : B. It has anti-H.pylori activity

Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct

Last Answer : D. Both A and B are correct

Description : Omeprazole exerts practically no other action except inhibition of gastric acid secretion because: A. It transforms into the active cationic forms only in the acidic pH of the gastric juice B. Its ... forms are unable to diffuse out from the gastric parietal cell canaliculi D. All of the above

Last Answer : D. All of the above

Description : Enzyme responsible for the digestion of starch in food of main is Present in (e) Salivary and gastric secretion. (b) Salivary and pancreatic secretion (c) Gastric and pancreatic secretion (d) Gastric and duodenal secretion

Last Answer : (b) Salivary and pancreatic secretion

Description : Prokinetic drugs serve the following purpose(s) in gastroesophageal reflux disease: A. Reduce reflux of gastric contents into esophagus B. Promote healing of esophagitis C. Reduce acidity of gastric contents D. Both ‘A’ and ‘B’ are correct

Last Answer : A. Reduce reflux of gastric contents into esophagus

Description : The following class of gastric antisecretory drug also reduce gastric motility and have primary effect on juice volume, with less marked effect on acid and pepsin A. Histamine H2 blockers B. Anticholinergics C. Proton pump inhibitors D. Prostaglandins

Last Answer : B. Anticholinergics

Description : Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

Last Answer : C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation

Description : Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

Last Answer : C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation

Description : The success of oral rehydration therapy of diarrhoea depends upon the following process in the intestinal mucosa: A. Sodium pump mediated Na+ absorption B. Glucose coupled Na+ absorption C. Bicarbonate coupled Na+ absorption D. Passive Na+ diffusion secondary to nutrient absorption

Last Answer : B. Glucose coupled Na+ absorption

Description : The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent ... efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

Last Answer : A. It is indicated in all patients of peptic ulcer

Description : Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion

Last Answer : D. Decreased nocturnal gastric secretion

Description : Select the drug(s) which afford(s) relief in gastroesophageal reflux by increasing lower esophageal sphincter tone and promoting gastric emptying, but without affecting acidity of gastric contents: A. Sodium alginate B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C

Last Answer : D. Both ‘B’ and ‘C’

Description : The following is true of proton pump inhibitors except: A. They are the most effective drugs for Zolinger Ellison syndrome B. Their prolonged use can cause atrophy of gastric mucosa C. They inhibit growth of H. pylori in stomach D. They have no effect on gastric motilit

Last Answer : B. Their prolonged use can cause atrophy of gastric mucosa

Description : Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 ... acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa

Last Answer : C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa

Description : Oxethazaine is used for anaesthetizing gastric mucosa because: A. It is not absorbed from the gastrointestinal tract B. It remains largely unionized in acidic medium C. It is highly ionized in acidic medium D. It produces no systemic effects even at high doses

Last Answer : B. It remains largely unionized in acidic medium

Description :  The isoenzyme cyclooxygenase-2 (COX-2) is expressed constitutively at the following site: A. Gastric mucosa B. Neutrophils C. Blood platelets D. Juxtaglomerular apparatus

Last Answer : D. Juxtaglomerular apparatus

Description : The distinctive feature of the isoenzyme cyclooxygenase-2 is: A. It is not inhibited by indomethacin B. It is inducible C. It generates cytoprotective prostagladins in gastric mucosa D. It is found only in foetal tissues

Last Answer : B. It is inducible

Description : The actions of platelet activating factor include the following except: A. Increased capillary permeability B. Bronchodilatation C. Vasodilatation D. Erosion of gastric mucosa

Last Answer : B. Bronchodilatation

Description : Which of the following terms describes a gastric secretion that combines with vitamin B-12 so that it can be absorbed? a) Intrinsic factor Lack of intrinsic factor is a common finding in the aged ... in protein digestion. d) Trypsin Trypsin is an enzyme that aids in the digestion of protein.

Last Answer : a) Intrinsic factor Lack of intrinsic factor is a common finding in the aged patient.

Description : Adherent mucoid alkaline substance covering the inner lining of stomach is to - (1) digest starch (2) act against bacteria (3) prevent the action of pepsin of mucosa (4) prevent viral infection

Last Answer : (3) prevent the action of pepsin of mucosa Explanation: The continuous adherent mucus layer is also a barrier to luminal pepsin, thereby protecting the underlying mucosa from proteolytic ... support surface neutralization of acid and act as a protective physical barrier against luminal pepsin.

Description : Adherent mucoid alkaline substance covering the inner lining of stomach is to : (1) digest starch (2) act against bacteria (3) prevent the action of pepsin of mucosa (4) prevent viral infection

Last Answer : prevent the action of pepsin of mucosa

Description : All of the following statements about cholecystokinin pancreozymin are true except (A) It is secreted by mucosa of small intestine (B) It stimulates secretion of pancreatic juice rich in enzymes (C) It stimulates contraction of gall bladder (D) It inhibits gastric motility

Last Answer : Answer : D

Description : Bromhexine acts by (a) Inhibiting cough center (b) Irritating gastric mucosa and reflexly increasing bronchial secretion (c) Depolymerizing mucopolysaccharides present (d) Desensitizing stretch receptors in the lungs

Last Answer : Ans: C

Description : Bromhexine acts by: A. Inhibiting cough centre B. Irritating gastric mucosa and reflexly increasing bronchial secretion C. Depolymerizing mucopolysaccharides present in sputum. D. Desensitizing stretch receptors in the lungs

Last Answer : C. Depolymerizing mucopolysaccharides present in sputum.

Description : Choose the drug which blocks basal as well as stimulated gastric acid secretion without affecting cholinergic, histaminergic or gastrin receptors: A. Famotidine B. Loxatidine C. Omeprazole D. Pirenzepine

Last Answer : C. Omeprazole

Description : Intravenous fentanyl is used in balanced anaesthesia to afford: A. Relaxation of chest muscles B. Analgesia C. Unconsciousness D. Suppression of gastric acid secretion

Last Answer : B. Analgesia

Description : Which of the following medications represents the category proton (gastric acid) pump inhibitors? a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine ... antagonist. d) Metronidazole (Flagyl) Metronidazole is an antibiotic, specifically an amebicide.

Last Answer : a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine-triphosphatase pump on the surface of the parietal cells.

Description : Select the correct statement about nitrous oxide: A. It irritates the respiratory mucosa B. It has poor analgesic action C. It is primarily used as a carrier and adjuvant to other anaesthetics D. It frequently induces post anaesthetic nausea and retching

Last Answer : C. It is primarily used as a carrier and adjuvant to other anaesthetics

Description : Rank the clinical scenarios in order of greatest likelihood of serious postoperative pulmonary complications. A. Transabdominal hysterectomy in an obese woman that requires 3 hours of anesthesia time. B. Right ... smoker. E. Modified radical mastectomy in a 58-year-old woman who is obese.

Last Answer : Answer: BDCAE DISCUSSION: If one considers the constellation of risk factors for pulmonary complications that is provided in tabular form in the accompanying chapter, one should ... is associated with relatively little postoperative pain, and provides free and unrestricted respiratory function