Description : Which of the following statements is true for lignocaine: A. It is an ester-linked local anaesthetic B. It is not likely to exhibit cross-sensitivity with procaine C. It has a shorter duration of action than procaine D. It is not a surface anaesthetic
Last Answer : B. It is not likely to exhibit cross-sensitivity with procaine
Description : The following local anaesthetic raises BP instead of tending to cause a fall: A. Cocaine B. Dibucaine C. Lignocaine D. Procaine
Last Answer : A. Cocaine
Description : Which of the following is a poor surface anaesthetic: A. Procaine B. Lignocaine C. Tetracaine D. Benoxinate
Last Answer : A. Procaine
Description : Choose the local anaesthetic that is specifically used to produce corneal anaesthesia for tonometry: A. Tetracaine B. Oxethazaine C. Ropivacaine D. Benoxinate
Last Answer : D. Benoxinate
Description : The following local anaesthetic is poorly water soluble, PABA derivative and primarily used for anorectal lesions, wounds and ulcers: A. Benzocaine B. Dibucaine C. Procaine D. Benoxinate
Last Answer : A. Benzocaine
Description : Emetine is now used only as a reserve drug for amoebiasis because: A. It is less effective than metronidazole B. It produces a slower response than metronidazole C. It has cardiotoxic potential D. It is not effective in extraintestinal amoebiasis
Last Answer : C. It has cardiotoxic potentia
Description : The local anaesthetics having amide linkage differ from those having ester linkage in that the amidelinked local anaesthetics: A. Are not surface anaesthetics B. Have a shorter duration of action C. Are degraded in the plasma D. Do not show cross-sensitivity with esterlinked local anaesthetic
Last Answer : D. Do not show cross-sensitivity with esterlinked local anaesth
Description : Which of the following drugs depresses automaticity of SA node as well as ectopic foci, abbreviates action potential duration of Purkinje fibres, and slows atrioventricular conduction: A. Propranolol B. Lignocaine C. Procainamide D. Bretylium
Last Answer : A. Propranolol
Description : The most significant feature of the antiarrhythmic action of lignocaine is: A. Suppression of phase-4 depolarization in ventricular ectopic foci B. Prolongation of action potential duration C. Prolongation of effective refractory period D. Depression of membrane responsiveness
Last Answer : A. Suppression of phase-4 depolarization in ventricular ectopic foci
Description : Low concentration of bupivacaine is preferred for spinal / epidural obstetric analgesia because: A. It has a longer duration of action B. It can produce sensory blockade without paralysing abdominal muscles C. ... in maternal tissues so that less reaches the foetus D. All of the above are correct
Last Answer : D. All of the above are correct
Description : Epidural anaesthesia differs from spinal anaesthesia in that: A. Epidural anaesthesia produces less cardiovascular complications B. Headache is more common after epidural anaesthesia C. Blood ... . Greater separation between sensory and motor blockade can be obtained with epidural anaesthes
Last Answer : D. Greater separation between sensory and motor blockade can be obtained with epidural anaesthesia
Description : The duration of spinal anaesthesia depends on each of the following except: A. Which local anaesthetic is used B. Concentration of the local anaesthetic used C. Posture of the patient D. Whether adrenaline has been added to the local anaesthetic
Last Answer : C. Posture of the patient
Description : The segmental level of spinal anaesthesia depends on: A. Volume of the local anaesthetic injected B. Specific gravity of the local anaesthetic solution C. Posture of the patient D. All of the above factors
Last Answer : D. All of the above factors
Description : n which of the following techniques the concentration of the local anaesthetic used is the lowest: A. Infiltration anaesthesia B. Nerve block anaesthesia C. Spinal anaesthesia D. Epidural anaesthesia
Last Answer : A. Infiltration anaesthesia
Description : Adrenaline added to local anaesthetic solution for infiltration anaesthesia affords the following except: A. Prolongs the duration of local anaesthesia B. Makes the injection less painful C. Provides a more bloodless field for surgery D. Reduces systemic toxicity of the local anaesthetic
Last Answer : B. Makes the injection less painful
Description : Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic
Last Answer : B. Prolongs the duration of local anaesthesia
Description : Which sensation is blocked first by low concentrations of a local anaesthetic: A. Pain B. Temperature C. Touch D. Deep pressure
Last Answer : A. Pain
Description : The following is not true of local anaesthetics: A. The local anaesthetic is required in the unionized form for penetrating the neuronal membrane B. The local anaesthetic approaches its receptor ... the resting state D. The local anaesthetic combines with its receptor in the ionized cationic form
Last Answer : C. The local anaesthetic binds to its receptor mainly when the Na+ channel is in the resting state
Description : Which of the following local anaesthetics is indicated in case of the need to long acting one after a surgical operation, A. Lidocaine B. Mepivacaine C. Bupivacaine (Marcaine)
Last Answer : C. Bupivacaine (Marcaine)
Description : Which of the following is not a semisynthetic penicillin: A. Procaine penicillin B. Ampicillin C. Cloxacillin D. Carbenicillin
Last Answer : A. Procaine penicillin
Description : The penicillin G preparation with the longest duration of action is: A. Benzathine penicillin B. Sodium penicillin C. Potassium penicillin D. Procaine penicillin
Last Answer : A. Benzathine penicillin
Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine
Last Answer : C. Morphine
Description : Select the general anaesthetic having the most marked uterine relaxant action: A. Propofol B. Halothane C. Nitrous oxide D. Ether
Last Answer : B. Halothane
Description : The general anaesthetic having significant cardiodepressant property is: A. Halothane B. Enflurane C. Ether D. Nitrous oxide
Last Answer : A. Halothane
Description : Started within 4-6 hours of acute myocardial infarction, which of the following drug(s) can reduce the area of necrosis and the attendant mortality: A. Propranolol B. Glyceryl trinitrate C. Lignocaine D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Select the drug which is used by intravenous infusion for emergency control of tachycardia and sudden rise in blood pressure: A. Amiodarone B. Lignocaine C. Esmolol D. Disopyramide
Last Answer : C. Esmolo
Description : The following is an orally active lignocaine congener used for both acute as well as chronic ventricular arrhythmias: A. Mexiletine B. Flecainide C. Moricizine D. Propafenone
Last Answer : A. Mexiletine
Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct
Description : yocardial Na+ channel blockade by lignocaine has the following characteristic: A. It blocks inactivated Na+ channels more than activated channels B. It blocks activated Na+ channels more than inactivated ... Na+ channels D. It produces more prominent blockade of atrial than ventricular Na+ channels
Last Answer : A. It blocks inactivated Na+ channels more than activated channels
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Last Answer : A. Disopyramide
Description : The following antiarrhythmic drug has the most prominent anticholinergic action: A. Disopyramide B. Quinidine C. Procainamide D. Lignocaine
Description : The antiarrhythmic drug which decreases both rate of depolarization (phase 0) as well as rate of repolarization (phase 3) of myocardial fibres is: A. Lignocaine B. Propranolol C. Quinidine D. Verapamil
Last Answer : C. Quinidine
Description : Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity: A. Lignocaine B. Quinidine C. Verapamil D. Amiodarone
Last Answer : A. Lignocaine
Description : A resting nerve is relatively resistant to blockade by lignocaine compared to one which is repeatedly stimulated because: A. Lignocaine penetrates resting nerve membrane poorly B. Lignocaine binds ... promotes ionization of lignocaine D. Nodes of Ranvier are inaccessible in the resting state
Last Answer : B. Lignocaine binds more avidly to the inactivated Na+ chan
Description : Sensitivity of a nerve fibre to blockade by lignocaine depends on: A. Whether the fibre is sensory or motor B. Whether the fibre is myelinated or nonmyelinated C. Internodal distances in the fibre D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : 'Diffusion hypoxia’ is likely to occur only after use of nitrous oxide because it: A. Is a respiratory depressant B. Has low blood solubility and is used in high concentration C. Is a very potent anaesthetic D. Interferes with diffusion of oxygen into the tissues
Last Answer : B. Has low blood solubility and is used in high concentration
Description : Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam
Last Answer : C. Ketamine
Description : The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression
Last Answer : B. Poor analgesia
Description : Residual CNS depression is least marked after the use of the following anaesthetic: A. Diazepam B. Thiopentone sodium C. Lorazepam D. Propofo
Last Answer : D. Propofol
Description : Select the general anaesthetic that is particularly suitable for outpatient surgery because of quick recovery and short-lived post-anaesthetic psychomotor impairment: A. Ether B. Halothane C. Enflurane D. Desflurane
Last Answer : D. Desflurane
Description : Malignant hyperthermia is a rare complication of use of the following anaesthetic: A. Ketamine B. Thiopentone sodium C. Halothane D. Ether
Last Answer : D. Ether
Description : s a general anaesthetic, halothane has the following advantages except: A. Very good analgesic action B. Noninflammable and nonexplosive C. Reasonably rapid induction of anaesthesia D. Pleasant and nonirritating
Last Answer : A. Very good analgesic action
Description : Ether is still used as a general anaesthetic in India, specially in peripheral hospitals because: A. It is nonexplosive B. It is pleasant smelling and nonirritating C. It induces anaesthesia rapidly D. It is cheap and can be administered without anaesthetic machine
Last Answer : A. It is nonexplosive
Description : Select the correct statement about nitrous oxide: A. It irritates the respiratory mucosa B. It has poor analgesic action C. It is primarily used as a carrier and adjuvant to other anaesthetics D. It frequently induces post anaesthetic nausea and retching
Last Answer : C. It is primarily used as a carrier and adjuvant to other anaesthetics
Description : The following general anaesthetic has poor muscle relaxant action: A. Ether B. Nitrous oxide C. Halothane D. Isoflurane
Last Answer : B. Nitrous oxide
Description : The following anaesthetic can be used by the open drop method: A. Ether B. Desflurane C. Halothane D. Isoflurane
Last Answer : A. Ether
Description : Select the inhalational general anaesthetic which is metabolized in the body to a significant extent: A. Sevoflurane B. Isoflurane C. Ether D. Halothane
Last Answer : D. Halothane
Description : The following factor delays induction with an inhaled general anaesthetic: A. Alveolar perfusion-ventilation mismatch B. Hyperventilation C. Low blood:gas partition coefficient of the anaesthetic D. Inclusion of 5% carbon dioxide in the inhaled gas mixture
Last Answer : A. Alveolar perfusion-ventilation mismatch
Description : Which general anaesthetic selectively inhibits excitatory NMDA receptors: A. Thiopentone B. Halothane C. Desflurane D. Ketamine
Last Answer : D. Ketamine