Choose the antimalarial drug effective against multidrug resistant P. falciparum, which rapidly terminates an attack of malarial fever, but has a short duration of action, so that recrudescence is common: A. Proguanil B. Mefloquine C. Amodiaquine D. Artemisinin

Choose the antimalarial drug effective against multidrug resistant P. falciparum, which rapidly terminates
an attack of malarial fever, but has a short duration
of action, so that recrudescence is common:
A. Proguanil
B. Mefloquine
C. Amodiaquine
D. Artemisinin
by

1 Answer

Answer :

D. Artemisinin
by

Related questions

An adult male living in nonmalarious area has to visit an area where chloroquine resistant P. falciparum is prevalent. He is intolerant to mefloquine and his G6PD status is unknown. Select the drug that you will prescribe for prophylaxis of malaria: A. Primaquine B. Doxycycline C. Amodiaquine D. Quinine

Description : An adult male living in nonmalarious area has to visit an area where chloroquine resistant P. falciparum is prevalent. He is intolerant to mefloquine and his G6PD status is unknown. Select the ... you will prescribe for prophylaxis of malaria: A. Primaquine B. Doxycycline C. Amodiaquine D. Quinine

Last Answer : B. Doxycycline

elect the drug/combination that you will prescribe as a prophylactic to a resident of non-endemic area who got posted for 6 months to an endemic area with low degree chloroquine resistance among P. falciparum: A. Quinine B. Proguanil + Chloroquine C. Pyrimethamine + Sulfadoxine D. Artemisinin

Description : elect the drug/combination that you will prescribe as a prophylactic to a resident of non-endemic area who got posted for 6 months to an endemic area with low degree chloroquine resistance among P. falciparum: A. Quinine B. Proguanil + Chloroquine C. Pyrimethamine + Sulfadoxine D. Artemisinin

Last Answer : B. Proguanil + Chloroquine

Select the drug which is a causal prophylactic for both falciparum and vivax malaria but is not used as prophylactic on mass scale due to risk of severe reaction in some individuals: A. Mefloquine B. Amodiaquine C. Primaquine D. Pyrimethamine

Description : Select the drug which is a causal prophylactic for both falciparum and vivax malaria but is not used as prophylactic on mass scale due to risk of severe reaction in some individuals: A. Mefloquine B. Amodiaquine C. Primaquine D. Pyrimethamine

Last Answer : C. Primaquine

The following antimalarial drug is more active against pre-and exoerythrocytic stages of the malarial parasite than against the erythrocytic stage: A. Proguanil B. Primaquine C. Pyrimethamine D. Halofantrine

Description : The following antimalarial drug is more active against pre-and exoerythrocytic stages of the malarial parasite than against the erythrocytic stage: A. Proguanil B. Primaquine C. Pyrimethamine D. Halofantrine

Last Answer : B. Primaquine

Use of the following antimalarial drug carries high risk of adverse effect in subjects with G-6-PD deficiency: A. Pyrimethamine B. Artemisinin C. Primaquine D. Mefloquine

Description : Use of the following antimalarial drug carries high risk of adverse effect in subjects with G-6-PD deficiency: A. Pyrimethamine B. Artemisinin C. Primaquine D. Mefloquine

Last Answer : C. Primaquine

Select the correct statement about primaquine: A. It has no role in falciparum malaria B. It is used as a gametocidal drug in falciparum malaria C. It is combined with chloroquine to treat resistant P. falciparum infection D. It is used to prevent recrudescence of falciparum malaria

Description : Select the correct statement about primaquine: A. It has no role in falciparum malaria B. It is used as a gametocidal drug in falciparum malaria C. It is combined with chloroquine to treat resistant P. falciparum infection D. It is used to prevent recrudescence of falciparum malaria

Last Answer : B. It is used as a gametocidal drug in falciparum malaria

Use of artemisinin derivatives is restricted to treatment of multidrug resistant falciparum malaria because: A. Wide spread use for all cases of malaria may foster development of resistant strains B. They are not active against P.vivax C. They are more toxic than quinine D. All of the above are correct

Description : Use of artemisinin derivatives is restricted to treatment of multidrug resistant falciparum malaria because: A. Wide spread use for all cases of malaria may foster development of resistant strains B. They are not ... P.vivax C. They are more toxic than quinine D. All of the above are correct

Last Answer : A. Wide spread use for all cases of malaria may foster development of resistant strain

Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum : (A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine

Description : Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum : (A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine

Last Answer : (B) Primaquine

The regimens recommended for treatment of chloroquine resistant P.falciparum malaria in an adult include the following except: A. Quinine 10 mg/kg/8 hourly+ doxycycline 100 mg/day for 7 days B. Quinine 10 mg/kg 3 times a day × 7 days with pyrimethamine 75 mg + sulfadoxine 1500 mg on first day C. Mefloquine 0.5 g daily for 7 days D. Artemether 80 mg i.m./twice on first day followed by once daily for 4 days

Description : The regimens recommended for treatment of chloroquine resistant P.falciparum malaria in an adult include the following except: A. Quinine 10 mg/kg/8 hourly+ doxycycline 100 mg/day for 7 days B. Quinine 10 mg/kg ... 7 days D. Artemether 80 mg i.m./twice on first day followed by once daily for 4 days

Last Answer : C. Mefloquine 0.5 g daily for 7 days

Recrudescence of malaria refers to recurrence of malarial fever due to: A. Reinfection of the patient by mosquito bite B. Reinfection of blood by exoerythrocytic hypnozoites C. Incomplete clearance of schizonts from blood D. Any of the above

Description : Recrudescence of malaria refers to recurrence of malarial fever due to: A. Reinfection of the patient by mosquito bite B. Reinfection of blood by exoerythrocytic hypnozoites C. Incomplete clearance of schizonts from blood D. Any of the above

Last Answer : C. Incomplete clearance of schizonts from blood

The drug of choice for cerebral malaria due to P. falciparum is: A. Quinine B. Mefloquine C. Chloroquine D. Pyrimethamine + Sulfadoxine

Description : The drug of choice for cerebral malaria due to P. falciparum is: A. Quinine B. Mefloquine C. Chloroquine D. Pyrimethamine + Sulfadoxine

Last Answer : A. Quinine

Recrudescences attending 3 day artesunate therapy of chloroquine resistant falciparum malaria can be prevented by combining it with a single dose of: A. Quinine B. Primaquine C. Tetracycline D. Mefloquine

Description : Recrudescences attending 3 day artesunate therapy of chloroquine resistant falciparum malaria can be prevented by combining it with a single dose of: A. Quinine B. Primaquine C. Tetracycline D. Mefloquine

Last Answer : D. Mefloquine

The following drug should be used only as clinical curative but not as prophylactic in malaria: A. Pyrimethamine + sulfadoxine B. Proguanil C. Primaquine D. Mefloquine

Description : The following drug should be used only as clinical curative but not as prophylactic in malaria: A. Pyrimethamine + sulfadoxine B. Proguanil C. Primaquine D. Mefloquine

Last Answer : A. Pyrimethamine + sulfadoxine

The fastest acting schizontocidal drug among the following is: A. Artemether B. Mefloquine C. Chloroquine D. Proguanil

Description : The fastest acting schizontocidal drug among the following is: A. Artemether B. Mefloquine C. Chloroquine D. Proguanil

Last Answer : A. Artemether

Indicate the drug that is a slow acting low efficacy blood schizontocide that should not be used as a clinical curative: A. Proguanil B. Chloroquine C. Quinine D. Mefloquine

Description : Indicate the drug that is a slow acting low efficacy blood schizontocide that should not be used as a clinical curative: A. Proguanil B. Chloroquine C. Quinine D. Mefloquine

Last Answer : A. Proguanil

The following drug is a causal prophylactic for falciparum malaria and suppressive prophylactic for vivax malaria: A. Chloroquine B. Mepacrine C. Quinine D. Proguanil

Description : The following drug is a causal prophylactic for falciparum malaria and suppressive prophylactic for vivax malaria: A. Chloroquine B. Mepacrine C. Quinine D. Proguanil

Last Answer : D. Proguanil

The following is true of mefloquine: A. P. falciparum does not develop resistance to mefloquine B. Concurrent use of β blockers with mefloquine is contraindicated C. Neuropsychiatric reactions are the most important adverse effects of mefloquine D. All of the above

Description : The following is true of mefloquine: A. P. falciparum does not develop resistance to mefloquine B. Concurrent use of β blockers with mefloquine is contraindicated C. Neuropsychiatric reactions are the most important adverse effects of mefloquine D. All of the above

Last Answer : C. Neuropsychiatric reactions are the most important adverse effects of mefloquine

The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin

Description : The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin

Last Answer : B. Adenosine

Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Description : Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Last Answer : A. Clinical curative in areas with chloroquine resistant malaria

Chloroquine resistant P. falciparum malaria can be cured by the following drugs except: A. Quinine B. Pyrimethamine + sulfadoxine C. Primaquine D. Artesunate

Description : Chloroquine resistant P. falciparum malaria can be cured by the following drugs except: A. Quinine B. Pyrimethamine + sulfadoxine C. Primaquine D. Artesunate

Last Answer : C. Primaquine

Malignant tertian malarial parasite, belongs to class (a) Plasmodium falciparum (b) P. vivax (c) P. ovale (d) P. malariae.

Description : Malignant tertian malarial parasite, belongs to class (a) Plasmodium falciparum (b) P. vivax (c) P. ovale (d) P. malariae.

Last Answer : (a) Plasmodium falciparum

If a drug is active against the preerythrocytic stage of the malarial parasite it will be useful as a: A. Suppressive prophylactic B. Causal prophylactic C. Clinical curative D. Radical curative

Description : If a drug is active against the preerythrocytic stage of the malarial parasite it will be useful as a: A. Suppressive prophylactic B. Causal prophylactic C. Clinical curative D. Radical curative

Last Answer : B. Causal prophylactic

Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

Description : Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

Last Answer : D. Lisinopri

Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis

Description : Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis

Last Answer : C. It is used orally to treat genital herpes simplex

Choose the correct statement about moclobemide: A. It is a reversible inhibitor of MAO-A with short duration of action B. Patients taking it need to be cautioned not to consume tyramine rich food C. It is contraindicated in elderly patients D. It produces anticholinergic side effect

Description : Choose the correct statement about moclobemide: A. It is a reversible inhibitor of MAO-A with short duration of action B. Patients taking it need to be cautioned not to consume tyramine rich food C. It is contraindicated in elderly patients D. It produces anticholinergic side effect

Last Answer : A. It is a reversible inhibitor of MAO-A with short duration of action

Indicate the drug that can be used as an alternative to primaquine for radical cure of vivax malaria: A. Atovaquone B. Bulaquine C. Tetracycline D. Proguanil

Description : Indicate the drug that can be used as an alternative to primaquine for radical cure of vivax malaria: A. Atovaquone B. Bulaquine C. Tetracycline D. Proguanil

Last Answer : B. Bulaquine

The total dose of chloroquine (base) for treatment of an episode of malarial fever in a nonimmune adult is: A. 1000 mg B. 1500 mg C. 2000 mg D. 2500 mg

Description : The total dose of chloroquine (base) for treatment of an episode of malarial fever in a nonimmune adult is: A. 1000 mg B. 1500 mg C. 2000 mg D. 2500 mg

Last Answer : B. 1500 mg

Proguanil is not used as a clinical curative in malaria because: A. Its schizontocidal action is slow B. Resistance to proguanil is widespread C. It is more toxic than chloroquine D. All of the above are correct

Description : Proguanil is not used as a clinical curative in malaria because: A. Its schizontocidal action is slow B. Resistance to proguanil is widespread C. It is more toxic than chloroquine D. All of the above are correct

Last Answer : A. Its schizontocidal action is slow

Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment of migraine attacks C. Use of ergot alkaloids is restricted to severe or resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

Description : Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment ... resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

Last Answer : C. Use of ergot alkaloids is restricted to severe or resistant cases

The following drug is a radical curative in vivax malaria: A. Quinine B. Primaquine C. Mefloquine D. Chloroquine

Description : The following drug is a radical curative in vivax malaria: A. Quinine B. Primaquine C. Mefloquine D. Chloroquine

Last Answer : B. Primaquine

Erythrocytic schizontocide antimalarial drugs are used as: A. Suppressive prophylactic B. Clinical curative C. Radical curative for P.vivax D. Both ‘A’ and ‘B’

Description : Erythrocytic schizontocide antimalarial drugs are used as: A. Suppressive prophylactic B. Clinical curative C. Radical curative for P.vivax D. Both ‘A’ and ‘B’

Last Answer : D. Both ‘A’ and ‘B’

The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake

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Last Answer : C. Axonal uptake

Chloroquine acts as: A. Preerythrocytic schizontocide for both P. falciparum and P. vivax B. Erythrocytic schizontocide for both P. falciparum and P. vivax C. Exoerythrocytic schizontocide for P. vivax D. Gametocidal for P. falciparum

Description : Chloroquine acts as: A. Preerythrocytic schizontocide for both P. falciparum and P. vivax B. Erythrocytic schizontocide for both P. falciparum and P. vivax C. Exoerythrocytic schizontocide for P. vivax D. Gametocidal for P. falciparum

Last Answer : B. Erythrocytic schizontocide for both P. falciparum and P. vivax

he multidrug therapy of leprosy is superior to monotherapy on the following account(s): A. It prevents emergence of dapsone resistance B. It is effective in cases with primary dapsone resistance C. It shortens the total duration of drug therapy and improves compliance D. All of the above

Description : he multidrug therapy of leprosy is superior to monotherapy on the following account(s): A. It prevents emergence of dapsone resistance B. It is effective in cases with primary dapsone resistance C. It shortens the total duration of drug therapy and improves compliance D. All of the above

Last Answer : D. All of the above

The antitubercular action of thiacetazone has the following feature(s): A. It is a low efficacy antitubercular drug B. It is combined with isoniazid to improve anti-tubercular efficacy of the latter C. It is combined with isoniazid to prevent development of resistant infection D. Both ‘A’ and ‘C’ are correc

Description : The antitubercular action of thiacetazone has the following feature(s): A. It is a low efficacy antitubercular drug B. It is combined with isoniazid to improve anti-tubercular efficacy of the latter C. ... with isoniazid to prevent development of resistant infection D. Both A' and C' are correc

Last Answer : D. Both ‘A’ and ‘C’ are correct

Choose the semisynthetic penicillin which has an extended spectrum of activity against many gram negative bacilli, is acid resistant but not penicillinase resistant: A. Cloxacillin B. Amoxicillin C. Phenoxymethyl penicillin D. Piperacillin

Description : Choose the semisynthetic penicillin which has an extended spectrum of activity against many gram negative bacilli, is acid resistant but not penicillinase resistant: A. Cloxacillin B. Amoxicillin C. Phenoxymethyl penicillin D. Piperacillin

Last Answer : B. Amoxicillin

The most significant feature of the antiarrhythmic action of lignocaine is: A. Suppression of phase-4 depolarization in ventricular ectopic foci B. Prolongation of action potential duration C. Prolongation of effective refractory period D. Depression of membrane responsiveness

Description : The most significant feature of the antiarrhythmic action of lignocaine is: A. Suppression of phase-4 depolarization in ventricular ectopic foci B. Prolongation of action potential duration C. Prolongation of effective refractory period D. Depression of membrane responsiveness

Last Answer : A. Suppression of phase-4 depolarization in ventricular ectopic foci

The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion

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Last Answer : C. It is the drug of choice for enterococcal endocarditis

Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis

Description : Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis

Last Answer : A. Typhoid fever

n addition to malarial parasite, chloroquine is active against: A. Microfilariae B. Trichomonas vaginalis C. Entamoeba histolytica D. Dermatophytes

Description : n addition to malarial parasite, chloroquine is active against: A. Microfilariae B. Trichomonas vaginalis C. Entamoeba histolytica D. Dermatophytes

Last Answer : C. Entamoeba histolytica

The following strategy will promote rather than curb emergence of antibiotic resistant micro-organisms: A. Whenever possible use broad spectrum antibiotics B. Prefer a narrow spectrum antibiotic to a broad spectrum one if both are equally effective C. Prefer short and intensive courses of antibiotics D. Use antibiotic combinations for prolonged therapy

Description : The following strategy will promote rather than curb emergence of antibiotic resistant micro-organisms: A. Whenever possible use broad spectrum antibiotics B. Prefer a narrow spectrum ... Prefer short and intensive courses of antibiotics D. Use antibiotic combinations for prolonged therapy

Last Answer : A. Whenever possible use broad spectrum antibiotics

The most important reason for highly restricted use of penicillin G injections in present day therapeutics is its: A. Narrow spectrum of activity B. Potential to cause hypersensitivity reaction C. Short duration of action D. Neurotoxicity

Description : The most important reason for highly restricted use of penicillin G injections in present day therapeutics is its: A. Narrow spectrum of activity B. Potential to cause hypersensitivity reaction C. Short duration of action D. Neurotoxicity

Last Answer : B. Potential to cause hypersensitivity reaction

Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : A. They have potent antiovulatory action of their own

Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : B. They produce many side effects

Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct

Description : Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent suppression of gastric acid enhances efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

Description : The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent ... efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

Last Answer : A. It is indicated in all patients of peptic ulcer

Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem

Description : Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem

Last Answer : B. Amiodarone

Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

Description : Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

Last Answer : B. Zolpidem