The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion

The following is true of linezolid except:
A. It inhibits bacterial protein synthesis at an
early step
B. It is active against vancomycin resistant
enterococci
C. It is the drug of choice for enterococcal
endocarditis
D. It can be administered orally as well as by
i.v. infusion
by

1 Answer

Answer :

C. It is the drug of choice for enterococcal
endocarditis
by

Related questions

The following is true of vancomycin except: A. It is a bactericidal antibiotic active primarily against gram positive bacteria B. It acts by inhibiting bacterial protein synthesis C. It is an alternative to penicillin for enterococcal endocarditis D. It can cause deafness as a dose related toxicity

Description : The following is true of vancomycin except: A. It is a bactericidal antibiotic active primarily against gram positive bacteria B. It acts by inhibiting bacterial protein synthesis C. It is an alternative to penicillin for enterococcal endocarditis D. It can cause deafness as a dose related toxicity

Last Answer : B. It acts by inhibiting bacterial protein synthesis

In a patient with culture-positive enterococcal endocarditis who has failed to respond to vancomycin because of resistance, the treatment most likely to be effective is (a) Clarithromycin (b) Erythromycin (c) Linezolid (d) Minocycline (e) Ticarcillin

Description : In a patient with culture-positive enterococcal endocarditis who has failed to respond to vancomycin because of resistance, the treatment most likely to be effective is (a) Clarithromycin (b) Erythromycin (c) Linezolid (d) Minocycline (e) Ticarcillin

Last Answer : Ans: D

Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis

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Last Answer : C. It is used orally to treat genital herpes simplex

Select the antimicrobial agent that can be used to treat with both methicillin resistant and vancomycin resistant Staphylococcus aureus infection: A. Clarithromycin B. Clindamycin C. Linezolid D. Lincomycin

Description : Select the antimicrobial agent that can be used to treat with both methicillin resistant and vancomycin resistant Staphylococcus aureus infection: A. Clarithromycin B. Clindamycin C. Linezolid D. Lincomycin

Last Answer : C. Linezolid

What is true of Quinupristin-Dalfopristin: A. It is a synergistic combination of two similar antibiotics B. It acts by inhibiting bacterial protein synthesis C. It is active against most resistant coccal infections D. All of the above are correct

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A patient needs antibiotic treatment for native valve, culture-positive infective enterococcal endocarditis. His medical history includes a severe anaphylactic reaction to penicillin G during the past year. The best approach would be treatment with (a) Amoxicillin/clavulanate (b) Aztreonam (c) Cefazolin plus genatamicin (d) Meropenem (e) Vancomycin

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Last Answer : Ans: E

The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days C. Their dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

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Last Answer : A. They interfere with an early step in the synthesis of clotting factors

Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for: A. Agranulocytosis patients B. Prophylaxis of bacterial endocarditis in patients with valvular defects C. Prophylaxis of rheumatic fever D. Treatment of anthrax

Description : Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for: A. Agranulocytosis patients B. Prophylaxis of bacterial endocarditis in patients with valvular defects C. Prophylaxis of rheumatic fever D. Treatment of anthrax

Last Answer : C. Prophylaxis of rheumatic fever

Vancomycin inhibits _____________ synthesis. a. protein b. DNA c. bacterial cell wall d. RNA

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Last Answer : c. bacterial cell wall

Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis

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he following is true of desmopressin except: A. It is nonselective V1 and V2 receptor agonist B. It is more potent and longer acting than arginine vasopressin (AVP) C. It is preferred over AVP for treatment of diabetes insipidus D. It can be administered orally

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Last Answer : A. It is nonselective V1 and V2 receptor agonist

Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ribosome does not move along the mRNA and the peptide chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin

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Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to 50S ribosome and blocking translocation of peptide chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

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Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation

Select the antibiotic which inhibits drug metabolizing isoenzyme CYP3A4 resulting in potentially fatal drug interaction with terfenadine: A. Erythromycin B. Clindamycin C. Gentamicin D. Vancomycin

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Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate

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Last Answer : C. Sodium nitroprusside

Select the drug which administered orally causes cervical ripening in pregnant women to facilitate surgical abortion or induction of labour: A. Mifepristone B. Raloxifene C. Natural progesterone D. Levonorgestre

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Bacteriostatic drugs are unlikely to effect cure of bacterial infection in the following category of patients except: A. Diabetic patients B. Patients with allergic disorders C. Patients on corticosteroid therapy D. Subacute bacterial endocarditis patient

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The following drug reduces urine volume in both pituitary origin as well as renal diabetes insipidus and is orally active: A. Vasopressin B. Hydrochlorothiazide C. Chlorpropamide D. Carbamazepine

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Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for (a) Agranulocytosis patients (b) Prophylaxis of bacterial endocarditis in patients with valvular defects (c) Prophylaxis of rheumatic fever (d) Treatment of anthrax

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The distinctive feature of terbinafine is: A. It is highly effective in histoplasmosis B. It can be used topically as well as orally for dermatophytosis C. It inhibits Mucor and Aspergillus as well D. Applied intravaginally it cures both candida as well as trichomonas vaginitis

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An adult patient with a history of bacterial endocarditis requires prophylactic administration of antibiotics prior to removal of teeth. Indicate the pre-operative regimen:** A. Amoxicillin 2 gram one hour before operation orally B. Penicillin 250 mg orally six hours before operation C. Tetracycline 250-500 mg orally 2 hours before treatment

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Choose the orally active third generation cephalosporin having good activity against gram positive cocci as well: A. Cefdinir B. Ceftazidime C. Cefoperazone D. Ceftizoxime

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The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is: A. Cloxacillin B. Vancomycin C. Erythromycin D. Amikacin

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The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is (a) Cloxacillin (b) Vancomycin (c) Erythromycin (d) Amikacin

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Last Answer : Ans: B

Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low B. It is inactivated by the gut microflora C. It is not active against the microbes of the normal gut flora D. It is a potent tetracycline and inhibits

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Select the antimicrobial drug which is used orally only for urinary tract infection or for bacterial diarrhoeas: A. Nalidixic acid B. Azithromycin C. Bacampicillin D. Pefloxacin

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Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor

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Amoxicillin + Clavulanic acid is active against the following organisms except: A. Methicillin resistant Staph. aureus B. Penicillinase producing Staph. aureus C. Penicillinase producing N.gonorrhoeae D. β-lactamase producing E.coli

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Last Answer : A. Methicillin resistant Staph. aureus

Amoxicillin is inferior to ampicillin for the treatment of the following infection: A. Typhoid B. Shigella enteritis C. Subacute bacterial endocarditis D. Gonorrhoea

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Though penicillin G kills the causative organism, it is only of adjuvant value to other measures in: A. Diphtheria B. Subacute bacterial endocarditis C. Syphilis D. Anthrax

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Choose the correct statement about lactulose: A. It stimulates myenteric neurones to enhance gut peristalsis B. Administered orally it acts as a purgative within 2-4 hours C. It is an osmotic laxative that produces soft but formed stools D. All of the above are correct

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The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent suppression of gastric acid enhances efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

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Last Answer : A. It is indicated in all patients of peptic ulcer

The following is true of topiramate except: A. It is a broad spectrum antiepileptic drug B. It inhibits the enzyme carbonic anhydrase C. It is used as add-on therapy in refractory partial seizures D. It is not effective in generalized tonic-clonic seizures

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Last Answer : D. It is not effective in generalized tonic-clonic seizures

Piperacillin differs from carbenicillin in the following respect(s): A. It is more active against Pseudomonas aeruginosa B. It is active against Klebsiella as well C. It is acid resistant D. Both ‘A’ and ‘B’ are correct

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Last Answer : D. Both ‘A’ and ‘B’ are correct

Choose the correct statement about bambuterol: A. It is an orally acting bronchodilator B. It is a prodrug C. It inhibits the enzyme pseudocholinesterase D. All of the above

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Last Answer : D. All of the above

Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis

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Last Answer : B. It can be used topically to treat infected acne vulgaris

Trimethoprim inhibits bacteria without affecting mammalian cells because: A. It does not penetrate mammalian cells B. It has high affinity for bacterial but low affinity for mammalian dihydrofolate reductase enzyme C. It inhibits bacterial folate synthetase as well as dihydrofolate reductase enzymes D. All of the above

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Select the diuretic which is orally active, efficacious in acidosis as well as alkalosis, causes diuresis even in renal failure and has additional carbonic anhydrase inhibitory action: A. Mannitol B. Benzthiazide C. Indapamide D. Furosemide

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Last Answer : D. Furosemide

The following is an orally active lignocaine congener used for both acute as well as chronic ventricular arrhythmias: A. Mexiletine B. Flecainide C. Moricizine D. Propafenone

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Last Answer : D. Lipocortin

The following is true of abciximab except: A. It is a monoclonal antibody against GPIIb/IIIa B. It inhibits platelet aggregation induced by a variety of platelet agonists C. It is antigenic D. It is used to reduce the risk of restenosis in patients undergoing PTCA

Description : The following is true of abciximab except: A. It is a monoclonal antibody against GPIIb/IIIa B. It inhibits platelet aggregation induced by a variety of platelet agonists C. It is antigenic D. It is used to reduce the risk of restenosis in patients undergoing PTCA

Last Answer : C. It is antigenic

Cyclosporine has the following attributes except: A. It selectively suppresses humoral immunity without affecting cell mediated immunity B. It is more active as immunosuppressant when administered before antigen exposure than after it C. It is not toxic to the bone marrow D. Its major toxicity is kidney damage

Description : Cyclosporine has the following attributes except: A. It selectively suppresses humoral immunity without affecting cell mediated immunity B. It is more active as immunosuppressant when administered before antigen exposure ... It is not toxic to the bone marrow D. Its major toxicity is kidney damage

Last Answer : A. It selectively suppresses humoral immunity without affecting cell mediated immunity

Which of the following is a disease modifying antirheumatic drug whose active metabolite inhibits the enzyme dihydro-orotate dehydrogenase: A. Leflunomide B. Nimesulide C. Sulfasalazine D. Colchicine

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Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis? (a) Tetracycline (b) Erythromycin (c) Neomycin (d) Streptomycin

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.Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis? (a) Tetracycline (b) Erythromycin (c) Neomycin (d) Streptomycin

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Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low (b) It is inactivated by the gut microflora (c) It is not active against the microbes of the normal gut flora (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well

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Last Answer : Ans: A

Intravenous saline infusion is the treatment of choice for the following complication(s) of vigorous furosemide therapy: A. Dilutional hyponatremia B. Acute saline depletion C. Hypokalemia D. All of the above

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All of the following statements about puromycin are true except (A) It is an alanyl tRNA analogue (B) It causes premature termination of protein synthesis (C) It inhibits protein synthesis in prokaryotes (D) It inhibits protein synthesis in eukaryotes

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What is true about human interferon α: A. It is used to treat HIV infection B. It is used to treat Kaposi‘s sarcoma in AIDS patients C. It is curative for hepatitis B virus infection D. It is active orally

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