Use of artemisinin derivatives is restricted to treatment
of multidrug resistant falciparum malaria because:
A. Wide spread use for all cases of malaria may
foster development of resistant strains
B. They are not active against P.vivax
C. They are more toxic than quinine
D. All of the above are correct

1 Answer

Answer :

A. Wide spread use for all cases of malaria may
foster development of resistant strain

Related questions

Description : The regimens recommended for treatment of chloroquine resistant P.falciparum malaria in an adult include the following except: A. Quinine 10 mg/kg/8 hourly+ doxycycline 100 mg/day for 7 days B. Quinine 10 mg/kg ... 7 days D. Artemether 80 mg i.m./twice on first day followed by once daily for 4 days

Last Answer : C. Mefloquine 0.5 g daily for 7 days

Description : The following drug is a causal prophylactic for falciparum malaria and suppressive prophylactic for vivax malaria: A. Chloroquine B. Mepacrine C. Quinine D. Proguanil

Last Answer : D. Proguanil

Description : The following is true of quinine: A. It has a longer elimination half-life than chloroquine B. It is not to be used for prophylaxis of malaria C. It is not active against P. vivax D. It should not be used along with sulfa-pyrimethamine

Last Answer : B. It is not to be used for prophylaxis of malaria

Description : Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum : (A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine

Last Answer : (B) Primaquine

Description : Chloroquine resistant P. falciparum malaria can be cured by the following drugs except: A. Quinine B. Pyrimethamine + sulfadoxine C. Primaquine D. Artesunate

Last Answer : C. Primaquine

Description : An adult male living in nonmalarious area has to visit an area where chloroquine resistant P. falciparum is prevalent. He is intolerant to mefloquine and his G6PD status is unknown. Select the ... you will prescribe for prophylaxis of malaria: A. Primaquine B. Doxycycline C. Amodiaquine D. Quinine

Last Answer : B. Doxycycline

Description : Choose the antimalarial drug effective against multidrug resistant P. falciparum, which rapidly terminates an attack of malarial fever, but has a short duration of action, so that recrudescence is common: A. Proguanil B. Mefloquine C. Amodiaquine D. Artemisinin

Last Answer : D. Artemisinin

Description : elect the drug/combination that you will prescribe as a prophylactic to a resident of non-endemic area who got posted for 6 months to an endemic area with low degree chloroquine resistance among P. falciparum: A. Quinine B. Proguanil + Chloroquine C. Pyrimethamine + Sulfadoxine D. Artemisinin

Last Answer : B. Proguanil + Chloroquine

Description : Recrudescences attending 3 day artesunate therapy of chloroquine resistant falciparum malaria can be prevented by combining it with a single dose of: A. Quinine B. Primaquine C. Tetracycline D. Mefloquine

Last Answer : D. Mefloquine

Description : The drug of choice for cerebral malaria due to P. falciparum is: A. Quinine B. Mefloquine C. Chloroquine D. Pyrimethamine + Sulfadoxine

Last Answer : A. Quinine

Description : Select the correct statement about primaquine: A. It has no role in falciparum malaria B. It is used as a gametocidal drug in falciparum malaria C. It is combined with chloroquine to treat resistant P. falciparum infection D. It is used to prevent recrudescence of falciparum malaria

Last Answer : B. It is used as a gametocidal drug in falciparum malaria

Description : Select the drug which is a causal prophylactic for both falciparum and vivax malaria but is not used as prophylactic on mass scale due to risk of severe reaction in some individuals: A. Mefloquine B. Amodiaquine C. Primaquine D. Pyrimethamine

Last Answer : C. Primaquine

Description : Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Last Answer : A. Clinical curative in areas with chloroquine resistant malaria

Description : The following drug is a radical curative in vivax malaria: A. Quinine B. Primaquine C. Mefloquine D. Chloroquine

Last Answer : B. Primaquine

Description : Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis

Last Answer : C. It is used orally to treat genital herpes simplex

Description : Chloroquine acts as: A. Preerythrocytic schizontocide for both P. falciparum and P. vivax B. Erythrocytic schizontocide for both P. falciparum and P. vivax C. Exoerythrocytic schizontocide for P. vivax D. Gametocidal for P. falciparum

Last Answer : B. Erythrocytic schizontocide for both P. falciparum and P. vivax

Description : Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment ... resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

Last Answer : C. Use of ergot alkaloids is restricted to severe or resistant cases

Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin

Last Answer : Ans: A

Description : Radical cure of vivax malaria should be attempted in: A. Areas where only sporadic cases occur B. Endemic areas with effective vector control measures C. Endemic areas not covered by vector control D. Both ‘A’ and ‘B’ are correc

Last Answer : D. Both ‘A’ and ‘B’ are correc

Description : Clinical applications of quinine include the following except: A. Uncomplicated chloroquine resistant malaria B. Cerebral malaria C. To induce abortion D. Nocturnal leg cramps

Last Answer : C. To induce abortion

Description : Multidrug therapy with dapsone + rifampin ± clofazimine is the treatment of choice for: A. Multibacillary leprosy B. Paucibacillary leprosy C. Dapsone resistant leprosy D. All forms of leprosy

Last Answer : D. All forms of leprosy

Description : Clarithromycin is used for the following: A. Multidrug resistant M.tuberculosis infection B. M.avium complex infection in AIDS patient C. M.tuberculosis infection in a patient who develops jaundice due to first line antitubercular drugs D. Both ‘A’ and ‘B’ are correct

Last Answer : B. M.avium complex infection in AIDS patient

Description : Which fluoroquinolone is highly active against Mycobact. leprae and is being used in alternative multidrug therapy regimens: A. Norfloxacin B. Ofloxacin C. Ciprofloxacin D. Lomefloxacin

Last Answer : B. Ofloxacin

Description : Malignant tertian malarial parasite, belongs to class (a) Plasmodium falciparum (b) P. vivax (c) P. ovale (d) P. malariae.

Last Answer : (a) Plasmodium falciparum

Description : Multidrug resistant (MDR) tuberculosis is defined as resistance to: A. Any two or more antitubercular drugs B. Isoniazid + any other antitubercular drug C. Isoniazid + Rifampin + any one or more antitubercular drugs D. All five first line antitubercular drugs

Last Answer : C. Isoniazid + Rifampin + any one or more antitubercular drugs

Description : A patient of vivax malaria was treated with the standard dose of chloroquine. After 6 weeks he reported back with a relapse. Which drug will you use to treat the relapse episode: A. Chloroquine B. Primaquine C. Pyrimethamine + sulfadoxine D. Mefloquin

Last Answer : A. Chloroquine

Description : Indicate the drug that can be used as an alternative to primaquine for radical cure of vivax malaria: A. Atovaquone B. Bulaquine C. Tetracycline D. Proguanil

Last Answer : B. Bulaquine

Description : Proguanil is not used as a clinical curative in malaria because: A. Its schizontocidal action is slow B. Resistance to proguanil is widespread C. It is more toxic than chloroquine D. All of the above are correct

Last Answer : A. Its schizontocidal action is slow

Description : Widespread and prolonged use of an antibiotic leads to emergence of drug resistant strains because antibiotics: A. Induce mutation in the bacteria B. Promote conjugation among bacteria C. Allow resistant strains to propagate preferentially D. All of the above

Last Answer : C. Allow resistant strains to propagate preferentially

Description : Currently, under the mass programme (WHO/NLEP), the duration of multidrug therapy for multibacillary leprosy is: A. Two years fixed duration for all cases B. One year fixed duration for all cases C. ... for cases with bacillary index 3 or less and two years for cases with bacillary index 4 or more

Last Answer : B. One year fixed duration for all cases

Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci

Last Answer : Ans: C

Description : The following is true of multidrug therapy of leprosy except: A. It has been highly successful in paucibacillary but not in multibacillary cases B. Relapse rate is very low in both paucibacillary ... use once a month D. Prevalence of lepra reaction is not higher compared to dapsone monotherapy

Last Answer : A. It has been highly successful in paucibacillary but not in multibacillary cases

Description : he multidrug therapy of leprosy is superior to monotherapy on the following account(s): A. It prevents emergence of dapsone resistance B. It is effective in cases with primary dapsone resistance C. It shortens the total duration of drug therapy and improves compliance D. All of the above

Last Answer : D. All of the above

Description : Neomycin is widely used as a topical antibiotic because: A. It is active against a wide range of bacteria causing superfecial infections B. It rarely causes contact sensitization C. It is poorly absorbed from the topical sites of application D. All of the above are correct

Last Answer : D. All of the above are correct

Description : Antimicrobial drug combinations are aimed at achieving the following except: A. Faster and more complete elimination of the infecting organism B. Treat infection when nature and sensitivity of the infecting organism is not definite C. Prevent emergence of resistant strains D. Prevent superinfection

Last Answer : D. Prevent superinfection

Description : Piperacillin differs from carbenicillin in the following respect(s): A. It is more active against Pseudomonas aeruginosa B. It is active against Klebsiella as well C. It is acid resistant D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Description : What is true of Quinupristin-Dalfopristin: A. It is a synergistic combination of two similar antibiotics B. It acts by inhibiting bacterial protein synthesis C. It is active against most resistant coccal infections D. All of the above are correct

Last Answer : D. All of the above are correct

Description : Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

Description : The following is true of mefloquine: A. P. falciparum does not develop resistance to mefloquine B. Concurrent use of β blockers with mefloquine is contraindicated C. Neuropsychiatric reactions are the most important adverse effects of mefloquine D. All of the above

Last Answer : C. Neuropsychiatric reactions are the most important adverse effects of mefloquine

Description : Indicate the attribute that is common to both polymyxin B and bacitracin: A. Both are active against gram negative bacteria B. Both are too toxic for systemic use C. Both act by inhibiting bacterial cell wall synthesis D. Both a

Last Answer : B. Both are too toxic for systemic use

Description : The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion

Last Answer : C. It is the drug of choice for enterococcal endocarditis

Description : Amoxicillin + Clavulanic acid is active against the following organisms except: A. Methicillin resistant Staph. aureus B. Penicillinase producing Staph. aureus C. Penicillinase producing N.gonorrhoeae D. β-lactamase producing E.coli

Last Answer : A. Methicillin resistant Staph. aureus

Description : Erythrocytic schizontocide antimalarial drugs are used as: A. Suppressive prophylactic B. Clinical curative C. Radical curative for P.vivax D. Both ‘A’ and ‘B’

Last Answer : D. Both ‘A’ and ‘B’

Description : Quinine, the effective medicine in the treatment of malaria, is extracted from

Last Answer : Bark of Cinchona

Description : Which one of the following options gives the correct match of a disease with its causative organism and mode of infection? Disease Causative Mode of organism infection (a) Typhoid Salmonella ... infected bancrofti water and food (d) Malaria Plasmodium Bite of male vivax Anopheles mosquito

Last Answer : (a) Typhoid Salmonella With inspired typhi air

Description : Use of the following antimalarial drug carries high risk of adverse effect in subjects with G-6-PD deficiency: A. Pyrimethamine B. Artemisinin C. Primaquine D. Mefloquine

Last Answer : C. Primaquine

Description : Select the sulfonamide drug which is active against Pseudomonas and is used by topical application for prophylaxis of infection in burn cases: A. Sulfadiazine B. Silver sulfadiazine C. Sulfadoxine D. Sulfamethoxazole

Last Answer : B. Silver sulfadiazine

Description : Choose the correct statement(s) about auranofin: A. It is an orally active gold compound B. It is equally effective but less toxic than injected gold-sodium-thiomalate C. Its major adverse effect is dermatitis D. All of the above are correct

Last Answer : A. It is an orally active gold compound