Description : Mitochondrial thiokinase acts on (A) Short chain of fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Last Answer : Answer : A
Description : Long chain fatty acids penetrate the inner mitochondrial membrane (A) Freely (B) As acyl-CoA derivative (C) As carnitine derivative (D) Requiring Na dependent carrier
Last Answer : Answer : C
Description : Which of the following statements regarding mitochondrial membrane is not correct ? (a) The outer membrane resembles a sieve. (b) The outer membrane is permeable to all kinds of molecules. (c) ... in the outer membrane. (d) The inner membrane is highly convoluted forming a series of infoldings.
Last Answer : (c) The enzymes of the electron transfer chain are embedded in the outer membrane.
Description : Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by (A) cAMP (B) Prostaglandin (C) Carnitine (D) Choline
Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes
Last Answer : Answer : B
Description : Saliva contains a lipase which acts on triglycerides having (A) Short chain fatty acids (B) Medium chain fatty acids (C) Long chain fatty acids (D) All of these
Description : Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue
Last Answer : Answer : D
Description : C22 and C24, fatty acids required for the synthesis of sphingolipids in brain are formed by (A) De novo synthesis (B) Microsomal chain elongation (C) Mitochondrial chain elongation (D) All of these
Description : Where will you find short and medium chain fatty acids?
Last Answer : They are seen in butter, ghee, coconut oil and motherís milk.
Description : Which of the following statements regarding mitochondria is incorrect? (a) Mitochondrial matrix contains single circular DNA molecule and ribosomes. (b) Outer membrane is permeable to monomers of ... transport are embedded in outer membrane. (d) Inner membrane is convoluted with infoldings.
Last Answer : (c) Enzymes of electron transport are embedded in outer membrane.
Description : The major site for elongation of medium chain fatty acids is (A) Mitochondria (B) Cytosol (C) Microsomes (D) All of these
Description : What about medium and small chain fatty acids?
Last Answer : Medium chain fatty acids do not require carnitine for transport, so they are easily oxidised.
Description : All of the following statements about hypoglycin are true except (A) It is a plant toxin (B) It causes hypoglycaemia (C) It inhibits oxidation of short chain fatty acids (D) It inhibits oxidation of long chain fatty acids
Description : Carnitine is required for the transport of (A) Triglycerides out of liver (B) Triglycerides into mitochondria (C) Short chain fatty acids into mitochondria (D) Long chain fatty acids into mitochondria
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : In the extra mitochondrial synthesis of fatty acids, CO2 is utilized (A) To keep the system anaerobic and prevent regeneration of acetyl CoA (B) In the conversion of malonyl to CoA hydroxybutyryl CoA (C ... of acetyl CoA to malonyl CoA (D) In the formation of acetyl CoA from 1 carbon intermediates
Description : Which of the following component of respiratory chain is not attached to the inner mitochondrial membrane? (A) Coenzyme Q (B) Cytochrome c (C) Both (A) and (B) (D) None of these
Description : The redox carriers are grouped into respiratory chain complex (A) In the inner mitochondrial membrane (B) In mitochondiral matrix (C) On the outer mitochondrial membrane (D) On the inner surface of outer mitochondrial membrane
Description : All the following statements about carnitine are true except (A) It can be synthesised in the human body (B) It can be synthesized from methionine and lysine (C) It is required for transport of short chain fatty acids into mitochondria (D) Its deficiency can occur due to haemodialysis
Description : All of the following statements about nonsense codons are true except (A) They do not code for amino acids (B) They act as chain termination signals (C) They are identical in nuclear and mitochondrial DNA (D) They have no complementary anticodons
Description : The electron transport chain within the inner mitochondrial membrane creates a gradient of ____________ across the inner membrane which is utilized to drive the activity of ATP synthase and the generation of ATP.
Last Answer : Hydrogen (H+ ions) or protons
Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies
Description : All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation. (A) CO2 (B) Propionic acid (C) Acetic acid (D) Acetyl CoA
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : For the activation of long chain fatty acids the enzyme thiokinase requires the cofactor: (A) Mg++ (B) Ca++ (C) Mn++ (D) K+
Description : Long chain fatty acids are first activated to acyl CoA in the (A) Cytosol (B) Mitochodria (C) Ribosomes (D) Microsome
Description : Long chain fatty acids are first activated to acetyl-CoA in (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria
Description : How long chain fatty acids are absorbed?
Last Answer : Long chain fatty acids (chain length more than 14 carbons) are absorbed by forming micelles with the help of bile salts.
Description : It has been suggested that enterocyte-specific fuels be utilized for all patients receiving parenteral nutrition. Theoretically, the benefits of such fuels include: A. Glutamine increases ... parenteral nutrition for patients with chemotherapy toxicity or radiation enteritis is without hazards.
Last Answer : Answer: NONE IS ENTIRELY TRUE DISCUSSION: The use of enterocyte-specific fuels is part of a new and potentially exciting phase of nutritional pharmacology in parenteral nutrition; ... the maintenance of colonocyte-specific nutrition and, in the case of butyrate, ileal enterocyte nutrition
Description : The importance of phospholipids as constituent of cell membrane is because they possess (A) Fatty acids (B) Both polar and nonpolar groups (C) Glycerol (D) Phosphoric acid
Description : Fatty acids can be transported into and out of cell membrane by (A) Active transport (B) Facilitated transport (C) Diffusion (D) Osmosis
Last Answer : B
Description : The maximum possible chain length of fatty acids formed in the pathway of de novo synthesis is (A) 16 Carbon atoms (B) 18 Carbon atoms (C) 20 Carbon atoms (D) 24 Carbon atoms
Description : Chain elongation of fatty acids in mammalian liver occurs in (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes
Description : Chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular fractions of the cell? (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : Fatty acids having chain length of 10 carbon atoms enter the (A) Portal ciruclation (B) Lacteals (C) Systemic circulation (D) Colon
Description : The desaturation and chain elongation system of polyunsaturated fatty acids are greatly diminished in the absence of (A) Insulin (B) Glycagon (C) Epinephrine (D) Thyroxine
Description : What is the product of beta oxidation of odd chain fatty acids?
Last Answer : Propionyl CoA.
Description : How small chain fatty acids are absorbed?
Last Answer : Small chain and medium chain fatty acids (chain length less than 14 carbons) are directly absorbed from the intestinal lumen into the portal vein and taken to the liver.
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis
Description : The chemical inhibiting oxidative phosphorylation, Adependent on the transport of adenine nucleotides across the inner mitochondrial membrane is (A) Oligomycin (B) Atractyloside (C) Dinitrophenol (D) Pentachlorophenol
Description : Mitochondrial membrane is freely preamble to (A) Pyruvate (B) Malate (C) Oxaloacetate (D) Fumarate
Description : Carnitine acylcarnitine translocase is present (A) In the inner mitochondrial membrane (B) In the mitochondrial matrix (C) On the outer surface of inner mitochondrial membrane (D) On the inner surface of inner mitochondrial membrane
Description : All of the following statements about the enzymic complex that carries out the synthesis of ATP during oxidative phosphorylation are correct except (A) It is located on the matrix side of the inner ... inhibited by oligomycin (C) It can exhibit ATPase activity (D) It can bind molecular O2
Last Answer : D
Description : Electron transport and phosphorylation can be uncoupled by compounds that increase the permeability of the inner mitochondrial membrane to (A) Electrons (B) Protons (C) Uncouplers (D) All of these
Description : Enzymes catalyzing electron transport are present mainly in the (A) Ribosomes (B) Endoplasmic reticulum (C) Lysosomes (D) Inner mitochondrial membrane
Description : What is the difference for absorption of short chain fatty acid?
Last Answer : Short and medium chain fatty acids do not need re-esterification. They directly enter into blood vessels (Not to lacteals).
Description : Fatty acids are (a) Unsaturated dicarboxylic acids (b) Long-chain alkanoic acids (c) Aromatic carboxylic acids (d) Aromatic dicarboxylic acids
Last Answer : Long-chain alkanoic acids
Description : Which of the safeners counteract inhibition of synthesis of very long chain fatty acids in rice by pretilachlor and metolachlor a). Fenclorim b). Benoxacor c). Fluxofenim d). All
Last Answer : d). All