Description : Adrneal cortical response is poor in (A) Kwashiorkor (B) Marasmus (C) Fatty liver (D) Atherosclerosis HORMONE METABOLISM 229
Last Answer : Answer : A
Description : Down regulation is (A) Increased destruction of a hormone (B) Feed back inhibition of hormone secretion (C) Decreased concentration of a hormone in blood (D) Decrease in number of receptors for a hormone
Last Answer : Answer : D
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Last Answer : C
Description : An animal having food deficiency in any respect is (a) Starvation (b) Under nourishment (c) Malnourishment (d) Patient of kwashiorkor
Last Answer : (c) Malnourishment
Description : The metabolism of sodium is regulated by the hormone: (A) Insulin (B) Aldosterone (C) PTH (D) Somatostatin
Last Answer : Answer : B
Description : The half life of insulin is (A) < 3–5 minutes (B) < 8–10 minutes (C) < 15 minutes (D) < 15 minutes HORMONE METABOLISM 213
Description : BMR is decreased in all of the following except (A) Fever (B) Addison’s disease (C) Starvation (D) Hypothyroidism
Description : BMR is decreased in (A) Pregnancy (B) Starvation (C) Anaemia (D) Fever
Description : The filtration factor is decreased in (A) Glomerulonephritis (B) Early essential hypertension (C) Malignant phase of hypertension (D) Starvation
Description : A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation
Last Answer : Answers-1 The aetiology of gout can broadly be divided into cases where there is underexcretion of urate via the kidney (90%) or endogenous overproduction of uric acid (10%) although in practical ... diuretic use. Excessive dietary intake of purines is unlikely to be the main cause in this case.
Description : Hypoglycaemic coma can occur (A) In untreated diabetes mellitus (B) In starvation (C) After overdose of oral hypoglycaemic drugs (D) After overdose of insulin
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Description : Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer
Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Description : Which of the following statement(s) is/are true concerning protein/amino acid metabolism in man? a. The major source of amino acids is breakdown of circulating proteins b. The recommended daily ... balance refers to a decrease in nitrogen taken into the body versus the amount of nitrogen lost
Last Answer : Answer: b, d About 15% of the total body weight is made up of proteins, about half of which are intracellular and half extracellular. In man and other animals, dietary protein is the source of ... is exceeded by the amount of nitrogen lost in the urine, stool, skin, wounds, and fistula drainage
Description : Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors
Description : Hormone receptors that stimulate cAMP production (A) are part of a complex of two proteins that transform the external signal into internal cAMP production (B) are proteins distinct and separate from those ... binding of the hormone (D) are not very specific and bind a number of different hormones
Description : Hormone receptors possess all the following properties except (A) All of them are proteins (B) They possess a recognition domain (C) They bind hormones with a high degree of specificity (D) Number of receptors in a target cell is constant
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Last Answer : A
Description : Which of the following medications used for the treatment of obesity prevents the absorption of triglycerides? a) Orlistat (Xenical) Orlistat (Xenical) prevents the absorption of triglycerides. Side effects of ... (Prozac) has not been approved by the FDA for use in the treatment of obesity.
Last Answer : a) Orlistat (Xenical) Orlistat (Xenical) prevents the absorption of triglycerides. Side effects of Xenical may include increased bowel movements, gas with oily discharge, decreased food absorption, decreased bile flow, and decreased absorption of some vitamins.
Description : Action of insulin on lipid metabolism is (A) It increases lipolysis and increases triglyceride synthesis (B) It decreases lipolysis and increases triglyceride synthesis (C) It decreases ... and decreases triglyceride synthesis (D) It increases synthesis of triglyceride and increased ketogenesis
Description : The following feature disfavours use of oral hypoglycaemics in diabetes mellitus: A. Age at onset of disease over 40 years B. Insulin requirement more than 40 U/day C. Fasting blood sugar level between 100–200 mg/dl D. Associated obesity
Last Answer : B. Insulin requirement more than 40 U/day
Description : All the following statements about TSH are true except (A) It is a tropic hormone (B) It acts on para-follicular cells of thyroid glands (C) Its receptors are membrane-bound (D) Its second messenger is cyclic AMP
Description : All the following statements about ACTH are true except (A) It is a tropic hormone (B) Its target cells are located in adrenal cortex (C) Its receptors are located in the cell membrane (D) Its second messenger is inositol triphosphate
Description : G-proteins act as (A) Hormone carriers (B) Hormone receptors (C) Second messengers (D) Signal transducers
Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin
Description : Diabetes insipidus results from (A) Decreased insulin secretion (B) Decreased ADH secretion (C) Decreased aldosterone secretion (D) Unresponsiveness of osmoreceptors
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : Gluconeogenesis is decreased by (A) Glucagon (B) Epinephrine (C) Glucocorticoids (D) Insulin
Last Answer : D
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : Potassium metabolism is regulated by the hormone: (A) Aldosterone (B) PTH (C) Somatostatin (D) Estrogen
Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) ACTH (B) Glucagon (C) Vasopressin (D) Growth hormone
Last Answer : Answer : C
Description : Hormones act only on specific organs or tissues. These are called (A) Active sites (B) Reaction centre (C) Target organ/Tissue(D) Physiological site HORMONE METABOLISM 231
Description : The second messenger for many hormones is (A) ATP (B) cyclic AMP (C) cGMP (D) UTP HORMONE METABOLISM 227
Description : Placenta secretes all of the following except (A) FSH (B) Progesterone (C) Estrogen (D) Chorionic gonadotropin HORMONE METABOLISM 225
Description : Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223
Description : Acromegaly results from overproduction of (A) ACTH during childhood (B) TSH during adult life (C) Growth hormone during childhood (D) Growth hormone during adult life HORMONE METABOLISM 219
Description : Secretion of MSH is regulated by (A) Feedback mechanism (B) Melatonin (C) Hypothalamic hormones (D) ACTH HORMONE METABOLISM 217
Description : Conversion of testosterone to estradiol requires the enzyme: (A) Aromatase (B) Dehydrogenase (C) Lyase (D) Isomerase HORMONE METABOLISM 215
Description : The normal serum level of triiodothyronine (T3) is (A) 0.2–0.5 ng/ml (B) 0.7–2.0 ng/ml (C) 2.0–4.0 ng/ml (D) 5.0–8.0 ng/ml HORMONE METABOLISM 211
Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209
Description : A hormone secreted from posterior pituitary is (A) Vasopressin (B) Thyrotropic hormone (C) Prolactin (D) Adrenocorticotropic hormone CHAPTER 8 CHAPTER 8 HORMONE METABOLISM ABOLISM
Description : Kwashiorkor results from (A) Vitamin A deficiency (B) Vitamin D deficiency (C) Deficiency of minerals in diet (D) Protein and caloric deficiency in diet
Description : Protein deficiency disease is known as (A) Cushing’s disease (B) Fabry’s disease (C) Parkinson’s disease (D) Kwashiorkor and marasmus
Description : Marasmus differs from Kwashiorkor in the which of these following respect (A) Mental retardation occurs in kwashiorkor but not in marasmus (B) Growth is retarded in kwashiorkor but not in marasmus ... in marasmus but not kwashiorkor (D) Subcutaneous fat disappears in marasmus but not in kwashiorkor
Description : Kwashiorkor usually occurs in (A) The post-weaning period (B) Pregnancy (C) Lactation (D) Old age
Description : Clinical features of Kwashiorkor include all of the following except (A) Mental retardation (B) Muscle wasting (C) Oedema (D) Anaemia
Description : Kwashiorkor occurs when the diet is severely deficient in (A) Iron (B) Calories (C) Proteins (D) Essential fatty acids