Which pathway is correct for catabolism of purines to form uric acid? (A) Guanylate→Adenylate→Xanthine→hypoxanthine→Uric acid (B) Guanylate→inosinate→Xanthine→hypoxanthine→Uric acid (C) Adenylate→Inosinate→Xanthine hypoxanthine→Uric acid (D) Adenylate→Inosinate→hypoxanthine Xanthine→Uric acid

Which pathway is correct for catabolism of purines to form uric acid? (A) Guanylate→Adenylate→Xanthine→hypoxanthine→Uric acid (B) Guanylate→inosinate→Xanthine→hypoxanthine→Uric acid (C) Adenylate→Inosinate→Xanthine hypoxanthine→Uric acid (D) Adenylate→Inosinate→hypoxanthine Xanthine→Uric acid
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The correct sequence of the reactions of catabolism of adenosine to uric acid is (A) Adenosine→hypoxanthine→xanthine→uric acid (B) Adenosine→xanthine→inosine→uric acid (C) Adenosine→inosine→hypoxanthine→ xanthine uric acid (D) Adenosine→xanthine→inosine→hypoxanthine uric acid

Description : The correct sequence of the reactions of catabolism of adenosine to uric acid is (A) Adenosine→hypoxanthine→xanthine→uric acid (B) Adenosine→xanthine→inosine→uric acid (C) Adenosine→inosine→hypoxanthine→ xanthine uric acid (D) Adenosine→xanthine→inosine→hypoxanthine uric acid

Last Answer : Answer : C

The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Description : The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Last Answer : Answer : B

Free ammonia is released during (A) Oxidative deamination of glutamate (B) Catabolism of purines (C) Catabolism of pyrimidines (D) All of these

Description : Free ammonia is released during (A) Oxidative deamination of glutamate (B) Catabolism of purines (C) Catabolism of pyrimidines (D) All of these

Last Answer : Answer : D

In humans, the principal break down product of purines is (A) NH3 (B) Allantin (C) Alanine (D) Uric acid

Description : In humans, the principal break down product of purines is (A) NH3 (B) Allantin (C) Alanine (D) Uric acid

Last Answer : Answer : D

Uric acid is the catabolic end product of (A) Porphyrine (B) Purines (C) Pyrimidines (D) Pyridoxine

Description : Uric acid is the catabolic end product of (A) Porphyrine (B) Purines (C) Pyrimidines (D) Pyridoxine

Last Answer : Answer : A

In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Last Answer : Answer : B

All of the following statements about uric acid are true except (A) It is a catabolite of purines (B) It is excreted by the kidneys (C) It is undissociated at pH above 5.8 (D) It is less soluble than sodium urate

Description : All of the following statements about uric acid are true except (A) It is a catabolite of purines (B) It is excreted by the kidneys (C) It is undissociated at pH above 5.8 (D) It is less soluble than sodium urate

Last Answer : Answer : C

Uric acid is the end product of purine as well as protein catabolism in (A) Man (B) Fish (C) Birds (D) None of these

Description : Uric acid is the end product of purine as well as protein catabolism in (A) Man (B) Fish (C) Birds (D) None of these

Last Answer : Answer : C

The end product of purine catabolism in man is (A) Inosine (B) Hypoxanthine (C) Xanthine (D) Uric acid

Description : The end product of purine catabolism in man is (A) Inosine (B) Hypoxanthine (C) Xanthine (D) Uric acid

Last Answer : Answer : D

In humans end product of purine catabolism is (A) Uric acid (B) Urea (C) Allantoin (D) Xanthine

Description : In humans end product of purine catabolism is (A) Uric acid (B) Urea (C) Allantoin (D) Xanthine

Last Answer : Answer : A

Purines: a. include guanine b. are metabolized to uric acid c. are mainly synthesized in the liver d. all above

Description : Purines: a. include guanine b. are metabolized to uric acid c. are mainly synthesized in the liver d. all above

Last Answer : all above

Respiratory pathway is involved in both anobolis and catabolism it would hence be better to consider the respiratory pathway as an_____

Description : Respiratory pathway is involved in both anobolis and catabolism it would hence be better to consider the respiratory pathway as an_____

Last Answer : Respiratory pathway is involved in both anobolis and catabolism it would hence be better to consider the respiratory pathway as an_____

Respiratory pathway is involved in both anobolis and catabolism it would hence be better to consider the respiratory pathway as an_____

Description : Respiratory pathway is involved in both anobolis and catabolism it would hence be better to consider the respiratory pathway as an_____

Last Answer : Respiratory pathway is involved in both anobolis and catabolism it would hence be better to consider the respiratory pathway as an_____

Which of the following statements about nucleic acid is most correct? (A) Both pentose nucleic acid and deoxypentose nucleic acid contain the same pyrimidines (B) Both pentose nucleic acid and deoxypentose nucleic acid and deoxypentose nucleic acid Contain the same purines (C) RNA contains cytosine and thymine (D) DNA and RNA are hydrolysed by weak alkali

Description : Which of the following statements about nucleic acid is most correct? (A) Both pentose nucleic acid and deoxypentose nucleic acid contain the same pyrimidines (B) Both pentose nucleic acid and deoxypentose ... (C) RNA contains cytosine and thymine (D) DNA and RNA are hydrolysed by weak alkali

Last Answer : Answer : B

Glycine is not required for the formation of (A) Taurocholic acid (B) Creatine (C) Purines (D) Pyrimidines

Description : Glycine is not required for the formation of (A) Taurocholic acid (B) Creatine (C) Purines (D) Pyrimidines

Last Answer : Answer : A

Identify the correct molecule which controls the biosynthesis of proteins in living organisms. (A) DNA (B) RNA (C) Purines (D) Pyrimidines

Description : Identify the correct molecule which controls the biosynthesis of proteins in living organisms. (A) DNA (B) RNA (C) Purines (D) Pyrimidines

Last Answer : Answer : A

An enzyme involved in catabolism of catecholamines is (A) Dopa decarboxylase (B) Aromatic amino acid decarboxylase (C) Monoamine oxidase (D) Catechol oxidas

Description : An enzyme involved in catabolism of catecholamines is (A) Dopa decarboxylase (B) Aromatic amino acid decarboxylase (C) Monoamine oxidase (D) Catechol oxidas

Last Answer : Answer : C

The four nitrogen atoms of purines are derived from (A) Urea and NH3 (B) NH3, Glycine and Glutamate (C) NH3, Asparate and Glutamate (D) Aspartate, Glutamine and Glycine

Description : The four nitrogen atoms of purines are derived from (A) Urea and NH3 (B) NH3, Glycine and Glutamate (C) NH3, Asparate and Glutamate (D) Aspartate, Glutamine and Glycine

Last Answer : Answer : D

Nucleic acids can be detected by means of their absorption maxima near 260 nm. Their absorption in this range is due to (A) Proteins (B) Purines and pyrimidines (C) Ribose (D) Deoxyribose

Description : Nucleic acids can be detected by means of their absorption maxima near 260 nm. Their absorption in this range is due to (A) Proteins (B) Purines and pyrimidines (C) Ribose (D) Deoxyribose

Last Answer : Answer : B

All the following statements about primary gout are true except (A) Its inheritance is X-linked recessive (B) It can be due to increased activity of PRPP synthetase (C) It can be due to increased activity of hypoxanthine guanine phosphoribosyl transferase (D) De novo synthesis of purines is increased in it

Description : All the following statements about primary gout are true except (A) Its inheritance is X-linked recessive (B) It can be due to increased activity of PRPP synthetase (C) It can be ... activity of hypoxanthine guanine phosphoribosyl transferase (D) De novo synthesis of purines is increased in it

Last Answer : Answer : C

Dietary purines are catabolised in (A) Liver (B) Kidneys (C) Intesitnal mucosa (D) All of these

Description : Dietary purines are catabolised in (A) Liver (B) Kidneys (C) Intesitnal mucosa (D) All of these

Last Answer : Answer : C

Methylated purines and pyrimidines are characteristically present in (A) mRNA (B) hnRNA (C) tRNA (D) rRNA

Description : Methylated purines and pyrimidines are characteristically present in (A) mRNA (B) hnRNA (C) tRNA (D) rRNA

Last Answer : Answer : C

That sulfonamides act by inhibiting folate synthesis in bacteria is supported by the following findings except: A. Paraaminobenzoic acid antagonises the action of sulfonamides B. Methionine antagonises the action of sulfonamides C. Purines and thymidine present in pus antagonise the action of sulfonamides D. Bacteria that utilise folic acid taken up from the medium are insensitive to sulfonamides

Description : That sulfonamides act by inhibiting folate synthesis in bacteria is supported by the following findings except: A. Paraaminobenzoic acid antagonises the action of sulfonamides B. Methionine antagonises ... . Bacteria that utilise folic acid taken up from the medium are insensitive to sulfonamides

Last Answer : B. Methionine antagonises the action of sulfonamides

Catabolism of thymidylate gives (A) α-alanine (B) β-alanine (C) α-aminoisobutyrate (D) β-aminoisobutyrate

Description : Catabolism of thymidylate gives (A) α-alanine (B) β-alanine (C) α-aminoisobutyrate (D) β-aminoisobutyrate

Last Answer : Answer : D

The following coenzyme is required for catabolism of pyrimidine bases: (A) NADH (B) NADPH (C) FADH2 (D) None of these

Description : The following coenzyme is required for catabolism of pyrimidine bases: (A) NADH (B) NADPH (C) FADH2 (D) None of these

Last Answer : Answer : B

β -Alanine is formed from catabolism of (A) Thymine (B) Thymine and cytosine (C) Thymine and uracil (D) Cytosine and uracil

Description : β -Alanine is formed from catabolism of (A) Thymine (B) Thymine and cytosine (C) Thymine and uracil (D) Cytosine and uracil

Last Answer : Answer : D

Free ammonia is liberated during the catabolism of (A) Cytosine (B) Uracil (C) Thymine (D) All of these

Description : Free ammonia is liberated during the catabolism of (A) Cytosine (B) Uracil (C) Thymine (D) All of these

Last Answer : Answer : D

β -Aminoisobytyrate is formed from catabolism of (A) Cytosine (B) Uracil (C) Thymine (D) Xanthine

Description : β -Aminoisobytyrate is formed from catabolism of (A) Cytosine (B) Uracil (C) Thymine (D) Xanthine

Last Answer : Answer : C

Gout is a metabolic disorder of catabolism of (A) Pyrimidine (B) Purine (C) Alanine (D) Phenylalanine

Description : Gout is a metabolic disorder of catabolism of (A) Pyrimidine (B) Purine (C) Alanine (D) Phenylalanine

Last Answer : Answer : B

Coenzyme A is required for catabolism of (A) Leucine (B) Isoleucine (C) Valine (D) All of these

Description : Coenzyme A is required for catabolism of (A) Leucine (B) Isoleucine (C) Valine (D) All of these

Last Answer : Answer : D

Degradation of proteins to amino acids, glucose from carbohydrates and fatty acids from lipids is known as (A) Anabolism (B) Metabolism (C) Catabolism (D) Cretinism

Description : Degradation of proteins to amino acids, glucose from carbohydrates and fatty acids from lipids is known as (A) Anabolism (B) Metabolism (C) Catabolism (D) Cretinism

Last Answer : Answer : C

Sulphur containing amino acids after catabolism produces a substance which is excreted: (A) SO2 (B) HNO3 (C) H2SO4 (D) H3PO4

Description : Sulphur containing amino acids after catabolism produces a substance which is excreted: (A) SO2 (B) HNO3 (C) H2SO4 (D) H3PO4

Last Answer : Answer : C

The degradative Processess are categorized under the heading of (A) Anabolism (B) Catabolism (C) Metabolism (D) None of the above

Description : The degradative Processess are categorized under the heading of (A) Anabolism (B) Catabolism (C) Metabolism (D) None of the above

Last Answer : B

Organic compound of small molecular size is (A) Urea (B) Uric acid (C) Creatinine (D) Phosphates

Description : Organic compound of small molecular size is (A) Urea (B) Uric acid (C) Creatinine (D) Phosphates

Last Answer : Answer : A

All are true about lesch-nyhan syndrome except (A) Produces self-mutilation (B) Genetic deficiency of the enzyme (C) Elevated levels of uric acid in blood (D) Inheritance is autosomal recessive

Description : All are true about lesch-nyhan syndrome except (A) Produces self-mutilation (B) Genetic deficiency of the enzyme (C) Elevated levels of uric acid in blood (D) Inheritance is autosomal recessive

Last Answer : Answer : B

In most mammals, except primates, uric acid is metabolized by (A) Oxidation to allantoin (B) Reduction to NH3 (C) Hydrolysis to allantoin (D) Hydrolysis to NH3

Description : In most mammals, except primates, uric acid is metabolized by (A) Oxidation to allantoin (B) Reduction to NH3 (C) Hydrolysis to allantoin (D) Hydrolysis to NH3

Last Answer : Answer : A

In humans, the principal metabolic product of pyrimidines is (A) Uric acid (B) Allantoin (C) Hypoxanthine (D) β-alanine

Description : In humans, the principal metabolic product of pyrimidines is (A) Uric acid (B) Allantoin (C) Hypoxanthine (D) β-alanine

Last Answer : Answer : D

The probable metabolic defect in gents is (A) A defect in excretion of uric acid by kidney (B) An overproduction of pyrimidines (C) An overproduction of uric acid (D) Rise in calcium leading to deposition of calcium urate

Description : The probable metabolic defect in gents is (A) A defect in excretion of uric acid by kidney (B) An overproduction of pyrimidines (C) An overproduction of uric acid (D) Rise in calcium leading to deposition of calcium urate

Last Answer : Answer : C

Insoinic acid is the biological precursor of (A) Cytosine and Uric acid (B) Adenylve acid and Glucine floc acid (C) Orotic acid and Uridylic acid (D) Adenosine acid Thymidine

Description : Insoinic acid is the biological precursor of (A) Cytosine and Uric acid (B) Adenylve acid and Glucine floc acid (C) Orotic acid and Uridylic acid (D) Adenosine acid Thymidine

Last Answer : Answer : B

A drug which prevents uric acid synthesis by inhibiting the enzyme Xanthine oxidase is (A) Aspirin (B) Allopurinal (C) Colchicine (D) Phenyl benzoate

Description : A drug which prevents uric acid synthesis by inhibiting the enzyme Xanthine oxidase is (A) Aspirin (B) Allopurinal (C) Colchicine (D) Phenyl benzoate

Last Answer : Answer : B

When NH3 is perfused through a dog’s liver ______ is formed, while ______ is formed in the birds liver. (A) Urea, Uric acid (B) Urea, allantoin (C) Uric acid, creatinine (D) Uric acid, Urea

Description : When NH3 is perfused through a dog’s liver ______ is formed, while ______ is formed in the birds liver. (A) Urea, Uric acid (B) Urea, allantoin (C) Uric acid, creatinine (D) Uric acid, Urea

Last Answer : Answer : A

All of the following can occur in LeschNyhan syndrome except (A) Gouty arthritis (B) Uric acid stones (C) Retarted growth (D) Self-mutiliating behaviour

Description : All of the following can occur in LeschNyhan syndrome except (A) Gouty arthritis (B) Uric acid stones (C) Retarted growth (D) Self-mutiliating behaviour

Last Answer : Answer : C

Complete absence of hypoxanthine guanine phospharibosyl transferase causes (A) Primary gout (B) Immunodeficiency (C) Uric acid stones (D) Lesh-Nyhan syndrome

Description : Complete absence of hypoxanthine guanine phospharibosyl transferase causes (A) Primary gout (B) Immunodeficiency (C) Uric acid stones (D) Lesh-Nyhan syndrome

Last Answer : Answer : D

All of the following statements about allopurinol are true except (A) It is a structural analogue of uric acid (B) It can prevent uric acid stones in the kidneys (C) It increases the urinary excretion of xanthine and hypoxanthine (D) It is a competitive inhibitor of xanthine oxidase

Description : All of the following statements about allopurinol are true except (A) It is a structural analogue of uric acid (B) It can prevent uric acid stones in the kidneys (C) It increases the urinary excretion of xanthine and hypoxanthine (D) It is a competitive inhibitor of xanthine oxidase

Last Answer : Answer : A

All of the following statements about primary gout are true except (A) Uric acid stones may be formed in kidneys (B) Arthritis of small joints occurs commonly (C) Urinary excretion of uric acid is decreased (D) It occurs predominantly in males

Description : All of the following statements about primary gout are true except (A) Uric acid stones may be formed in kidneys (B) Arthritis of small joints occurs commonly (C) Urinary excretion of uric acid is decreased (D) It occurs predominantly in males

Last Answer : Answer : C

All of the following statements about uric acid are true except (A) It can be formed from allantoin (B) Formation of uric acid stones in kidneys can be decreased by alkalinisation of urine (C) Uric acid begins to dissociate at pH above 5.8 (D) It is present in plasma mainly as monosodium urate

Description : All of the following statements about uric acid are true except (A) It can be formed from allantoin (B) Formation of uric acid stones in kidneys can be decreased by alkalinisation of urine (C) Uric acid begins to dissociate at pH above 5.8 (D) It is present in plasma mainly as monosodium urate

Last Answer : Answer : A

Daily uric acid excretion in adult men is (A) 2–6 mg (B) 20–40 mg (C) 150–250 mg (D) 40–600 mg

Description : Daily uric acid excretion in adult men is (A) 2–6 mg (B) 20–40 mg (C) 150–250 mg (D) 40–600 mg

Last Answer : Answer : D

The major catabolic product of pyrimidines in human is (A) β-Alanine (B) Urea (C) Uric acid (D) Guanine

Description : The major catabolic product of pyrimidines in human is (A) β-Alanine (B) Urea (C) Uric acid (D) Guanine

Last Answer : Answer : A

Gout is characterized by increased plasma levels of (A) Urea (B) Uric acid (C) Creatine (D) Creatinine

Description : Gout is characterized by increased plasma levels of (A) Urea (B) Uric acid (C) Creatine (D) Creatinine

Last Answer : Answer : B

In mammals other than higher primates uric acid is converted by (A) Oxidation to allantoin (B) Reduction to ammonia (C) Hydrolysis to ammonia (D) Hydrolysis to allantoin

Description : In mammals other than higher primates uric acid is converted by (A) Oxidation to allantoin (B) Reduction to ammonia (C) Hydrolysis to ammonia (D) Hydrolysis to allantoin

Last Answer : Answer : A