Description : Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate
Last Answer : C. Sodium nitroprusside
Description : Which of the following drugs is a potassium channel opener: A. Nicorandil B. Hydralazine C. Glibenclamide D. Amiloride
Last Answer : D. Amiloride
Description : Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which ... a long duration of action D. Sod. nitroprusside has additional K+ channel opening action
Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different
Description : The following vasodilator(s) act(s) by opening K+ channels in the vascular smooth muscle: A. Dipyridamole B. Minoxidil C. Diazoxide D. Both ‘B’ and ‘C’
Last Answer : D. Both ‘B’ and ‘C
Description : Select the drug that may improve myocardial tolerance to ischaemia and reduce anginal attacks without altering heart rate, blood pressure or myocardial O2 consumption: A. Trimetazidine B. Nicorandil C. Dipyridamole D. Nicotinic acid
Last Answer : A. Trimetazidine
Description : Select the drug which is an ‘inodilator’ beneficial in refractory congestive heart failure: A. Nicorandil B. Amiodarone C. Amrinone D. Carvedilol
Last Answer : C. Amrinone
Description : A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as ... injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin
Last Answer : C. Intravenous infusion of sodium nitroprussid
Description : The following procedure for rapid lowering of BP in hypertensive urgency/emergency has been abandoned: A. Sublingual/oral nifedipine B. Intravenous glyceryl trinitrate infusion C. Intravenous sodium nitroprusside infusion D. Intravenous esmolol injection
Last Answer : A. Sublingual/oral nifedipine
Description : Diazoxide is an effective hypotensive, but is not used in the long-term treatment of hypertension because: A. It impairs glucose tolerance by inhibiting insulin release B. It inhibits uric acid ... causes marked Na+ and water retention leading to development of tolerance D. All of the above
Last Answer : D. All of the above
Description : Which of the following drugs is a potassium channel opener ? (a) Pinacidil (b) Hydralazine (c) Glibenclamide (d) Amiloride
Last Answer : Ans: A
Description : Organic nitrates have predominantly venodilator action because: A. They are selectively concentrated in veins B. Veins express larger quantities of enzymes that generate nitric oxide from nitrates C. Venous smooth muscle has greater capacity to relax D. All of the above are correct
Last Answer : B. Veins express larger quantities of enzymes that generate nitric oxide from nitrates
Description : Which of the following drug can result in result in cyanide poisoning? A. Amyl nitrite B. Hydroxycobalamine C. Sodium nitroprusside D. Sodium thiosulphate
Description : The following antihypertensive is used topically to treat alopacia areata: A. Hydralazine B. Prazosin C. Minoxidil D. Indapamide
Last Answer : C. Minoxidil
Description : Which of the following is a steroid 5α-reductase inhibitor that has been found useful in benign prostatic hypertrophy and male pattern baldness: A. Flutamide B. Finasteride C. Prazosin D. Minoxidil
Last Answer : B. Finasteride
Description : Select the drug(s) which afford(s) relief in gastroesophageal reflux by increasing lower esophageal sphincter tone and promoting gastric emptying, but without affecting acidity of gastric contents: A. Sodium alginate B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C
Last Answer : D. Both ‘B’ and ‘C’
Description : Select the drug which is an inhibitor of gastric mucosal proton pump: A. Carbenoxolone sodium B. Sucralfate C. Famotidine D. Lansoprazole
Last Answer : D. Lansoprazole
Description : Select the drug having a narrow spectrum antiepileptic activity restricted to absence seizures: A. Lamotrigine B. Ethosuccimide C. Sodium valproate D. Primidone
Last Answer : . Ethosuccimide
Description : Select the drug that is neither bronchodilator nor antiinflammatory, but has antihistaminic and mast cell stabilizing activity: A. Sodium cromoglycate B. Ketotifen C. Beclomethasone dipropionate D. Chlorpheniramine
Last Answer : B. Ketotifen
Description : Select the most appropriate drug for regular prophylactic therapy in a 10 year old child who suffers from exercise induced asthma: A. Oral salbutamol B. Oral theophylline C. Inhaled sodium cromoglycate D. Inhaled salmeterol
Last Answer : C. Inhaled sodium cromoglycate
Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide
Last Answer : C. Sodium valproate
Description : The following drug displaces plasma protein bound phenytoin as well as decreases its metabolism: A. Carbamazepine B. Sodium valproate C. Cimetidine D. Chloramphenicol
Last Answer : B. Sodium valproate
Description : Select the drug which is active against a variety of diarrhoea producing organisms like Giardia, Shigella, Salmonella as well as S. typhi and Trichomonas vaginalis, but is not a first line treatment for any of these: A. Metronidazole B. Mepacrine C. Cotrimoxazole D. Furazolidone
Last Answer : D. Furazolidone
Description : Select the prokinetic-antiemetic drug which at relatively higher doses blocks both dopamine D2 as well as 5-HT3 receptors and enhances acetylcholine release from myenteric neurones: A. Cisapride B. Prochlorperazine C. Metoclopramide D. Domperidon
Last Answer : C. Metoclopramide
Description : Select the drug that can help restore cardiac performance as well as prolong survival in CHF patients: A. Spironolactone B. Furosemide C. Dobutamine D. Metoprolol
Last Answer : D. Metoprolol
Description : Select the antiepileptic drug that is effective in manicdepressive illness as well: A. Ethosuccimide B. Primidone C. Phenobarbitone D. Carbamazepine
Last Answer : D. Carbamazepine
Description : Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment ... resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided
Last Answer : C. Use of ergot alkaloids is restricted to severe or resistant cases
Description : Write the molecular formulae of: 1. Copper oxide 2. Iron (III) chloride 3. Sodium hydroxide 4. Iron (II) sulphide 5. Lead (II) oxide 6. Hydrogen nitrate (nitric ... Hydrogen sulphate (sulphuric acid) 8. Calcium hydroxide 9. Magnesium carbonate 10.Ammonium carbonate
Last Answer : 1. Copper oxide - CuO 2. Iron (III) chloride - FeCl3 3. Sodium hydroxide - NaOH 4. Iron (II) sulphide - FeS 5. Lead (II) oxide - PbO 6. Hydrogen nitrate (nitric acid) - HNO3 7. ... ) - H2SO4 8. Calcium hydroxide - Ca(OH)2 9. Magnesium carbonate - MgCO3 10.Ammonium carbonate - (NH4)2CO3
Description : Which of the following reactions involve NEITHER oxidation nor reduction? w) burning antimony in chlorine x) decomposition of potassium chlorate y) reaction of sodium with water z) reaction of potassium hydroxide with nitric acid
Last Answer : ANSWER: Z -- REACTION OF POTASSIUM HYDROXIDE WITH NITRIC ACID
Description : A friend has very severe hypertension and asks about a drug her doctor wishes to prescribe. Her physician has explained that this drug is associated with tachycardia and fluid retention (which may be marked ... has described? (a) Captopril (b) Guanethidine (c) Minoxidil (d) Prazosin (e) Propranolol
Last Answer : Ans: C
Description : The penicillin G preparation with the longest duration of action is: A. Benzathine penicillin B. Sodium penicillin C. Potassium penicillin D. Procaine penicillin
Last Answer : A. Benzathine penicillin
Description : component of the management of moderately severe diabetic ketoacidosis: A. Insulin B. Intravenous fluids C. Potassium chloride D. Sodium bicarbonate
Last Answer : D. Sodium bicarbonate
Description : Which of the following measures is not an essential component of the management of moderately severe diabetic ketoacidosis: A. Insulin B. Intravenous fluids C. Potassium chloride D. Sodium bicarbonate
Last Answer : . Sodium bicarbonate
Description : The uses of sodium/potassium iodide include the following except: A. Preoperative preparation of Grave’s disease patient B. Prophylaxis of endemic goiter C. As antiseptic D. As expectorant
Last Answer : C. As antiseptic
Description : Use of potassium sparing diuretics in patients receiving the following drug needs close monitoring: A. Furosemide B. Hydrochlorothiazide C. Captopril D. Verapami
Last Answer : C. Captopril
Description : Select the general anaesthetic having the most marked uterine relaxant action: A. Propofol B. Halothane C. Nitrous oxide D. Ether
Last Answer : B. Halothane
Description : Select the correct statement about nitrous oxide: A. It irritates the respiratory mucosa B. It has poor analgesic action C. It is primarily used as a carrier and adjuvant to other anaesthetics D. It frequently induces post anaesthetic nausea and retching
Last Answer : C. It is primarily used as a carrier and adjuvant to other anaesthetics
Description : Sodium valproate has been shown to: A. Prolong neuronal Na+ channel inactivation B. Attenuate ‘T’ type Ca2+ current in neurones C. Inhibit degradation of GABA by GABA-transaminase D. All of the above
Description : Sodium nitroprusside `Na_(2)[Fe(CN)_(5)NO]` is used as a reagent for the detection of
Last Answer : Sodium nitroprusside `Na_(2)[Fe(CN)_(5)NO]` is used as a reagent for the detection of A. sulphur B. nitrogen C. bromine D. iodine.
Description : Which statements is/are correct about sodium nitroprusside test ?
Last Answer : Which statements is/are correct about sodium nitroprusside test ? A. This test is used ... `+2` oxidation state in sodiumthionitroprusside complex.
Description : Thiol group of cysteine gives red colour with (A) Sodium acetate (B) Lead acetate (C) Sodium nitroprusside (D) Barfoed’s reagent
Last Answer : Answer : C
Description : All of the following may be useful in the treatment of cardiogenic shock except: A. Dobutamine. B. Sodium nitroprusside. C. Pneumatic antishock garment. D. Intra-aortic balloon pump.
Last Answer : Answer: C DISCUSSION: Cardiogenic shock occurs when the heart fails to generate adequate cardiac output to maintain tissue perfusion. Intrinsic causes such as myocardial dysfunction secondary ... ), which causes an increase in systemic vascular resistance, is contraindicated in cardiogenic shock
Description : The presence of Cobalt in Vitamin B12 was established for the first time by – (1) Hydrolysis test (2) Spectroscopy (3) Borax-Bead test (4) Sodium Nitroprusside test
Last Answer : (2) Spectroscopy Explanation: Atomic absorption spectroscopy is an analytical chemistry technique used for determining concentration of particular metal element and is widely used in pharmaceutics. It was used for the determination of cobalt in Vitamin B12.
Description : Vasoactive drugs which cause the arteries and veins to dilate, thereby shunting much of the intravascular volume to the periphery and causing a reduction in preload and afterload include agents ... Furosemide (Lasix) Furosemide (Lasix) is a loop diuretic that reduces intravascular fluid volume.
Last Answer : a) Sodium nitroprusside (Nipride) Sodium nitroprusside is used in the treatment of cardiogenic shock.
Description : The presence of Cobalt in Vitamin B12 was established for the first time by (1) Hydrolysis test (2) Spectroscopy (3) Borax-Bead test (4) Sodium Nitroprusside test
Last Answer : Spectroscopy
Description : Which anthelmintic drug acts through a specific glutamate gated Cl– ion channel found only in nematodes: A. Ivermectin B. Niclosamide C. Pyrantel pamoate D. Praziquantel
Last Answer : A. Ivermectin
Description : Choose the correct statement about trimetazidine: A. It is a novel calcium channel blocker B. It improves tissue perfusion by modifying rheological property of blood C. It is an antianginal drug which acts by nonhaemodynamic mechanisms D. Both 'A' and 'B' are correct
Last Answer : C. It is an antianginal drug which acts by nonhaemodynamic mechanisms
Description : A drug that decreases blood pressure and has analgesic and spasmolytic effects when given intrathecally is (a) Atenolol (b) Clonidine (c) Morphine (d) Nitroprusside (e) Prazosin
Last Answer : Ans: B
Description : Sodium chloride, potassium chloride, magnesium oxide are examples of molecules with (a) Covalent bonding (b) Ionic bonding (c) Metallic bonding (d) Hydrogen bonding
Last Answer : Ans:(b)
Description : With respect to calibration of uv-vis spectrophotometer, which of the following material is used to evaluate the ‘control of absorbance’ A. Sodium thiosulphate B. Potassium dichromate C. Holmium oxide D. Potassium permanganate
Last Answer : B. Potassium dichromate
Description : Which of the following would be least soluble in water? w) Carbon Tetrachloride x) Sodium Oxide y) Magnesium Bromide z) Potassium Phosphate
Last Answer : ANSWER: W -- CARBON TETRACHLORIDE