Description : The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in ... locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug
Last Answer : B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally
Description : Mesalazine (coated 5-amino salicylic acid) differs from sulfasalazine in that: A. It is more effective in ulcerative colitis B. It produces less adverse effect C. It has no therapeutic effect in rheumatoid arthritis D. Both ‘B’ and ‘C’ are correc
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Which of the following is a reserve drug but not a disease modifying drug in rheumatoid arthritis: A. Chloroquine B. Sulfasalazine C. Prednisolone D. Methotrexate
Last Answer : C. Prednisolone
Description : Sulfasalazine is used in the following disease(s): A. Bacillary dysentery B. Ulcerative colitis C. Rheumatoid arthritis D. Both ‘B’ and ‘C’ are correct
Description : To be effective in ulcerative colitis, 5-aminosalicylic acid has to be given as: A. Acrylic polymer coated tablet which releases the drug only in the lower bowel B. A complex of two molecules joined together by azo bond C. A retention enema D. Any of the above ways
Last Answer : D. Any of the above ways
Description : The following is not a valid indication for parenteral iron therapy: A. Inadequate response to oral iron due to patient noncompliance B. Anaemia during pregnancy C. Severe anaemia associated with chronic bleeding D. Anaemia in a patient of active rheumatoid arthritis
Last Answer : B. Anaemia during pregnancy
Description : Corticosteroid therapy is practically mandatory in the following condition: A. Septic shock B. Renal transplant C. Rheumatoid arthritis D. Ulcerative colitis
Last Answer : B. Renal transplan
Description : The following antirheumatic drug affords symptomatic relief but does not bring about remission in rheumatoid arthritis: A. Gold sodium thiomalate B. Prednisolone C. Hydroxychloroquine D. Leflunomide
Last Answer : B. Prednisolone
Description : Choose the correct statement about use of gold sod. thiomalate in rheumatoid arthritis: A. It affords more rapid symptomatic relief than NSAIDs B. The NSAIDs therapy is discontinued when it is ... D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed
Last Answer : D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed
Description : The selective COX-2 inhibitors have the following advantage(s) over the nonselective NSAIDs: A. They are less likely to cause gastric ulcers and their complications B. They are likely to be more ... in rheumatoid arthritis C. They are not likely to produce renal complications D. All of the above
Last Answer : A. They are less likely to cause gastric ulcers and their complications
Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above
Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition
Description : Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which ... a long duration of action D. Sod. nitroprusside has additional K+ channel opening action
Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different
Description : The primary role of sulfasalazine in ulcerative colitis is: A. Suppression of enteroinvasive pathogens B. Control of acute exacerbations of the disease C. Maintenance of remission D. Both ‘B’ and ‘C’
Last Answer : C. Maintenance of remission
Description : The preferred drug for controlling an acute exacerbation of ulcerative colitis is: A. Prednisolone B. Sulfasalazine C. Mesalazine D. Vancomycin
Last Answer : . Prednisolone
Description : Among the disease modifying antirheumatic drugs, fastest symptom relief is obtained with: A. Auranofin B. Hydroxychloroquine C. Sulfasalazine D. Methotrexate
Last Answer : D. Methotrexate
Description : Which of the following is a disease modifying antirheumatic drug whose active metabolite inhibits the enzyme dihydro-orotate dehydrogenase: A. Leflunomide B. Nimesulide C. Sulfasalazine D. Colchicine
Last Answer : A. Leflunomide
Description : When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action
Last Answer : C. Therapeutic window phenomenon
Description : Allopurinol has a therapeutic effect in the following conditions except: A. Radiotherapy induced hyperuricaemia B. Hydrochlorothiazide induced hyperuricaemia C. Acute gouty arthritis D. Kala-azar
Last Answer : C. Acute gouty arthritis
Description : You are treating a patient of deep vein thrombosis with warfarin. What value of International normalized ratio (INR) will you attempt by adjusting dose of the anticoagulant for an adequate therapeutic effect: A. 1.2 – 1.5 B. 1.3 – 1.7 C. 1.5 – 2.0 D. 2.0 – 3.0
Last Answer : D. 2.0 – 3.0
Description : For therapeutic effect in manic depressive illness, steady-state serum lithium concentration should be maintained between: A. 0.2–0.4 mEq/L B. 0.5–0.8 mEq/L C. 1.0–1.3 mEq/L D. 1.5–2.5 mEq/L
Last Answer : B. 0.5–0.8 mEq/L
Description : n a failing heart therapeutic dose of digoxin has no effect on the following parameter: A. Cardiac output B. Heart rate C. Tone of ventricular fibres D. Cardiac vagal tone
Last Answer : C. Tone of ventricular fibres
Description : The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate
Last Answer : C. Codergocrine
Description : A patient of endogenous depression was put on imipramine therapy. After what interval the therapeutic effect is likely to manifest: A. Three days B. One week C. Three weeks D. Three months
Last Answer : C. Three weeks
Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case
Last Answer : D. They are the preferred drugs in advanced cases
Description : The following is true about entacapone except: A. It acts by inhibiting degradation of dopamine in the brain B. If prolongs the therapeutic effect of levodopacarbidopa in parkinsonism C. It can accentuate levodopa induced dyskinesias D. It can cause diarrhoea as a side effec
Last Answer : A. It acts by inhibiting degradation of dopamine in the brain
Description : The primary action by which entacapone and tolcapone enhance the therapeutic effect of levodopa-carbidopa in parkinsonism is: A. Inhibition of levodopa methylation in the liver B. Inhibition of ... of dopamine in the brain D. Facilitation of active transport of levodopa across brain capillaries
Last Answer : A. Inhibition of levodopa methylation in the liver
Description : Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. ... its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop
Last Answer : C. Used alone, its effective doses produce intolerable side effect
Description : The drug which abolishes the therapeutic effect of levodopa in parkinsonism, but not that of levodopacarbidopa combination is: A. Metoclopramide B. Pyridoxine C. Chlorpromazine D. Isoniazid
Last Answer : B. Pyridoxine
Description : The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above
Last Answer : B. Levodopa
Description : The site of action of miotics for therapeutic effect in angle closure glaucoma is: A. Canal of Schlemm B. Ciliary body C. Ciliary muscle D. Sphincter pupillae muscle
Last Answer : D. Sphincter pupillae muscle
Description : Used as a remission inducing agent in rheumatoid arthritis, hydroxychloroquine: A. Is more effective than chloroquine B. Produces a lower incidence of retinal damage than chloroquine C. Is more effective and more toxic than gold D. Both ‘A’ and ‘B’ are correct
Last Answer : B. Produces a lower incidence of retinal damage than chloroquine
Description : In the intact animal H2 receptor antagonists potentiate the following action of histamine: A. Cardiac stimulation B. Fall in blood pressure C. Uterine relaxation D. Bronchospasm
Last Answer : D. Bronchospasm
Description : Do you know someone who has been diagnosed with Rheumatoid Arthritis?
Last Answer : I don't know anyone who has it, but I know a little bit about it since it's an autoimmune disease (in the same class of conditions that I have). With RA as with most autoimmune diseases, there ... sign of trouble. A history of RA in your close relatives is a risk factor for you getting RA yourself.
Description : Do the drugs Orencia and Rituxan work in the same manner on rheumatoid arthritis?
Last Answer : Orencia interferes with T-cell activation. Rituxan destroys B-cells. B and T cells are both part of the immune system and RA is a systemic autoimmune diesase, so both are trying to stop the ... of the joints by switching off part of the immune system but they are switching off different parts.
Description : I'm on a biolgic treatment for rheumatoid arthritis (Orencia) can I get a tatoo?
Last Answer : This is a good question for your doctor. I don’t remember reading any restrictions about tattoos when I was on Remicade (another biologic) but I’m not a doctor.
Description : I am looking for solutions to arthritis inflamation (specifically rheumatoid arthritis). Can anyone suggest?
Last Answer : answer:Try raw honey. Read up on it. I take it with cinnamon for other benefits but, I have heard some amazing claims about the effects of raw honey on arthritis pain.
Description : The distinct difference between these two drugs. Orencia and Remicade for rheumatoid arthritis?.
Last Answer : Maybe this will help.
Description : Is Gold Treatment still widely used for the treatment of rheumatoid arthritis?
Last Answer : Obsolete. You can google treatments for RA- there’s lots of newer treatments.
Description : Anyone out there with rheumatoid arthritis on EMBREL or HUMARA?
Last Answer : Contact the Rheumatology Department of a major hospital near you and inquire about local support groups for RA patients. I have located an RA support group for you online. To join go to HERE:“http://www.dailystrength.org/c/Rheumatoid-Arthritis/support-group” Good luck!
Description : Describe the symptoms of rheumatoid arthritis ?
Last Answer : Answer : Symptoms of rheumatoid arthritis are: 1. Swelling of the joints. 2. Feeling pain in the joints. 3. Do not move the joints. 4. The bones of the joints are removed and deformed.
Last Answer : Need Answer
Description : Juvenile rheumatoid arthritis?
Last Answer : DefinitionJuvenile rheumatoid Arthritis (JRA) is a term used to describe a common type of arthritis in children. It is a long-term (chronic) disease resulting in joint pain and swelling.Alternative ... form of JRA may turn into rheumatoid arthritis. It may involve large and small joints of
Description : Rheumatoid arthritis?
Last Answer : DefinitionRheumatoid Arthritis (RA) is a long-term disease that leads to inflammation of the joints and surrounding tissues. It can also affect other organs.Alternative NamesRA; Arthritis - rheumatoidCauses, ... The course and the severity of the illness can vary considerably. Infection, genes, and
Description : What is the best natural remedy for rheumatoid arthritis?
Last Answer : The best natural remedies for rheumatoid Arthritis are usually centered around the omega 3 fatty acids. Other natural remedies include gamma-linolenic acids, boswellia and devil's claw.
Description : Where online can I find out about Rheumatoid Arthritis symptoms?
Last Answer : You can find the symptoms for Rheumatoid Arthritis on the following website..www.nhs.uk/Conditions/Rheumatoid-arthritis/Pages/Living-with.aspx I hope this helps, good luck.
Description : How can I treat rheumatoid arthritis and any good dietary modifications?
Last Answer : As the exact causes of rheumatoid Arthritis are unknown, there are no known steps that can be taken in order to prevent the condition. As for treatment options, most patients are prescribed non- ... there are no diet modifications that can be made in order to prevent or treat rheumatoid arthritis.
Description : What are some of the rheumatoid arthritis treatments out there?
Last Answer : There are medications that can treat rheumatoid Arthritis and the pain that is associated with it. Certain diets and exercise have been connected to dealing with rheumatoid arthritis more effectively also.
Description : What are some treatment options for rheumatoid arthritis?
Last Answer : Getting regular exercise strengthens joint-supporting structures and improves flexibility. A physical therapist can suggest appropriate movements that provide a full range of motion.
Description : Am I at risk for rheumatoid arthritis?
Last Answer : Rheumatoid Arthritis is not a hereditary condition. While it is not passed down parents, certain genes that make you more susceptible to rheumatoid arthritis are.
Description : Treatment Options for Rheumatoid Arthritis?
Last Answer : Decades ago, if a person were diagnosed with rheumatoid Arthritis, the rheumatologist would tell that person that he or she would have a poor prognosis and would likely be disabled in in the future ... understanding this disease process, there is hope a better treatment or even a cure will be found.