You are treating a patient of deep vein thrombosis
with warfarin. What value of International normalized
ratio (INR) will you attempt by adjusting dose of the
anticoagulant for an adequate therapeutic effect:
A. 1.2 – 1.5
B. 1.3 – 1.7
C. 1.5 – 2.0
D. 2.0 – 3.0

1 Answer

Answer :

D. 2.0 – 3.0

Related questions

Description : A patient to be commenced on oral anticoagulant therapy for DVT would be treated with (a) Oral anticoagulant therapy with warfarin for a goal intenational normalized ration (INR) of 2-3 (b) Oral anticoagulant therapy ... of 2.5-3.5 (c) Oral anticoagulant therapy with aspirin for a goal INR of 2-3

Last Answer : Ans: A

Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis

Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time

Description : A patient has an episode of hematemesis following streptokinase infused for the treatment of deep vein thrombosis. Which of the following drugs would be most effective in controlling the bleeding episode: A. Vitamin K B. Noradrenaline C. Epsilon aminocaproic acid D. Rutin

Last Answer : C. Epsilon aminocaproic acid

Description : A patient on oral anticoagulant therapy is commenced on sulfamethoxazoletrimethoprim, double-strength twice daily. One may expect to see the international normalized ratio (a) Increase (b) Decrease (c) Remain unchanged

Last Answer : Ans: A

Description : A patient who has had a previous stroke and is taking warfarin tells the nurse that he started taking garlic to help reduce his blood pressure. The nurse knows that garlic when taken ... headaches. Garlic and warfarin taken together can greatly increase the INR, increasing the risk of bleeding.

Last Answer : a) can greatly increase the international normalization ratio (INR) and therefore increase the risk of bleeding. Garlic and warfarin taken together can greatly increase the INR, increasing the risk of bleeding.

Description : Low dose subcutaneous heparin therapy is indicated for: A. Prevention of leg vein thrombosis in elderly patients undergoing abdominal surgery B. Ischaemic stroke C. Patients undergoing neurosurgery D. Prevention of extention of coronary artery thrombus in acute myocardial infarction

Last Answer : A. Prevention of leg vein thrombosis in eld

Description : Thrombolytic therapy is indicated in the following conditions except: A. Acute myocardial infarction B. Stroke due to cerebral thrombosis C. Deep vein thrombosis D. Large pulmonary embolism

Last Answer : B. Stroke due to cerebral thrombosis

Description : In a patient of hypertension, the dose of propranolol that normalized blood pressure, reduced resting heart rate to 50/min. Which of the following β blockers will be most suitable for him as an ... so that heart rate is not markedly reduced: A. Pindolol B. Celiprolol C. Bisoprolol D. Atenolol

Last Answer : A. Pindolol

Description : In a patient of hypertension, the dose of propranolol that normalized blood pressure, reduced resting heart rate to 50/min. Which of the following β blockers will be most suitable for him as an ... so that heart rate is not markedly reduced: A. Pindolol B. Celiprolol C. Bisoprolol D. Atenolol

Last Answer : A. Pindolol

Description : Anticoagulant medication is indicated in: A. Immobilized elederly patients B. Buerger’s disease C. Stroke due to cerebral thrombosis D. All of the above

Last Answer : A. Immobilized elederly patients

Description : Combined therapy with dipyridamole and warfarin is recommended in subjects with the following: A. Risk factors for coronary artery disease B. Prosthetic heart valves C. Cerebral thrombosis D. Buerger's disease

Last Answer : B. Prosthetic heart valves

Description : The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their ... dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

Last Answer : A. They interfere with an early step in the synthesis of clotting factors

Description : Oral contraceptive use increases the risk of occurrence of the following diseases except: A. Hypertension B. Leg vein thrombosis C. Endometrial carcinoma D. Gall stones

Last Answer : C. Endometrial carcinoma

Description : Estrogen replacement therapy for postmenopausal women is contraindicated in subjects with: A. Leg vein thrombosis B. Undiagnosed vaginal bleeding C. Migraine D. All of the above

Last Answer : D. All of the above

Description : Why should care be taken when prescribing warfarin and amiodarone in combination? A. Amiodarone and warfarin both have an anticoagulant effect. B. Amiodarone may reverse the anticoagulant ... anticoagulant effect of warfarin. D. Warfarin may reverse the antiarrhythmic effect of amiodarone.

Last Answer : C. Amiodarone may increase the anticoagulant effect of warfarin. 

Description : External pneumatic compression has been advocated for the prevention of deep venous thrombosis during operative procedures. Which of the following statement(s) concerning the use of external pneumatic ... includes through the operation and for at least several days in the postoperative period

Last Answer : Answer: b, c, d In many well-controlled studies of venous prophylaxis, intermittent pneumatic compression has been found to be as effective as low-dose heparin therapy. In addition to augmentation ... be used through the operation and for at least five days in the face or prolonged immobilization

Description : n a failing heart therapeutic dose of digoxin has no effect on the following parameter: A. Cardiac output B. Heart rate C. Tone of ventricular fibres D. Cardiac vagal tone

Last Answer : C. Tone of ventricular fibres

Description : The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

Last Answer : B. Levodopa

Description : Which of the following is a valid therapeutic use of interaction? A. Use of Probenecid with Penicillin B. Giving Aspirin with warfarin C. Instructing patient to take levofloxacin with milk or antacid D. Treatment of depression of MAO Inhibitor and Citalopram

Last Answer : A. Use of Probenecid with Penicillin 

Description : How do you know that it's not Deep Vein Thrombosis but something much less serious? See detail.

Last Answer : I sent this to our MD – Caravanfan.

Description : What are the symptoms of deep vein thrombosis?

Last Answer : If you are concerned that you are having symptoms of deep vein thrombosis, the best thing to do would make an appointment with your doctor. They will be able to do tests to confirm.

Description : What are the symptoms of a deep vein thrombosis?

Last Answer : Your red leg could be crucial blood clots. Blood clots are symptoms of deep vein thrombosis. Red, swollen, and warm legs are three of the symptoms of deep vein thrombosis. You should probably go to a doctor , and have it checked out.

Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin

Last Answer : B. Warfarin

Description : A patient of endogenous depression was put on imipramine therapy. After what interval the therapeutic effect is likely to manifest: A. Three days B. One week C. Three weeks D. Three months

Last Answer : C. Three weeks

Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Description : Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin

Last Answer : B. Affects extrinsic system and decreases prothrombin time

Description : Which of the following statement(s) is/are true concerning the results of a National Institute of Health Consensus Conference on venous thrombosis and low-dose heparin prophylaxis? a. The odds of ... treated with low-dose heparin d. There was no difference in the incidence of bleeding complications

Last Answer : Answer: a, b, c In a metaanalysis of 70 randomized trials in 16,000 patients comparing low-dose heparin prophylaxis with standard therapy, the odds of developing deep venous thrombosis ... Similarly, the effectiveness of prophylaxis was not influenced by either two or three times daily dosage

Description : Angiotensin converting enzyme inhibitors afford maximum protection against progression of heart failure when used: A. At the higher therapeutic dose range over long term B. At the maximum tolerated dose only till ... restored C. At low doses over long term D. At low doses along with diuretics/digoxi

Last Answer : A. At the higher therapeutic dose range over long term

Description : Benzodiazepines differ from barbiturates in the following aspects except: A. They have a steeper dose response curve B. They have higher therapeutic index C. They have lower abuse liability D. They do not induce microsomal drug metabolizing enzymes

Last Answer : A. They have a steeper dose response curve

Description : Relatively higher dose of theophylline is required to attain therapeutic plasma concentration in: A. Smokers B. Congestive heart failure patients C. Those receiving erythromycin D. Those receiving cimetidine

Last Answer : A. Smokers

Description : A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Last Answer : C. 0.5 – 1.0 g% per week

Description : The most common and important undesirable effect of injectable contraceptive depot medroxyprogesterone acetate is: A. Nausea and vomiting B. Disruption of cyclic menstrual bleeding C. Venous thrombosis D. Hypertension

Last Answer : B. Disruption of cyclic menstrual bleeding

Description : For therapeutic effect in manic depressive illness, steady-state serum lithium concentration should be maintained between: A. 0.2–0.4 mEq/L B. 0.5–0.8 mEq/L C. 1.0–1.3 mEq/L D. 1.5–2.5 mEq/L

Last Answer : B. 0.5–0.8 mEq/L

Description : A patient being treated with 20 mg prednisolone daily has to be shifted on to dexamethasone. What should be his daily dose of dexamethasone: A. 0.75 mg B. 3 mg C. 10 mg D. 40 mg

Last Answer : B. 3 mg

Description : Renal vein thrombosis?

Last Answer : DefinitionRenal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney.Alternative NamesClot in the renal vein; Occlusion - renal veinCauses, incidence, and ... specific problem, but may indicate nephrotic syndrome or other causes of renal vein thrombosis.Abdom

Description : Which of the following statement(s) concerning intravenous nutritional support is/are true? a. Concentrations of glucose no higher than 5% should be used to avoid peripheral vein sclerosis ... suitable site d. Venous thrombosis is an uncommon complication for long-term central vein catheterization

Last Answer : Answer: b Although peripheral access can be used for intravenous nutrition, the major disadvantage of this technique is limited caloric delivery to meet catabolic demands within tolerated fluid ... studies that use phlebography or radionucleotide venography indicate the incidence is as high as 35%

Description : Commotio retinae is seen in: a. Concussion injury b. Papilloedema c. Central retinal vein thrombosis d. Central retinal artery thrombosis

Last Answer : a

Description : Neovascular glaucoma follows: a. Thrombosis of central retinal vein b. Acute congestive glaucoma c. Staphylococcal infection d. Hypertension

Last Answer : ANSWER: A 

Description : Mesalazine (coated 5-amino salicylic acid) differs from sulfasalazine in that: A. It is more effective in ulcerative colitis B. It produces less adverse effect C. It has no therapeutic effect in rheumatoid arthritis D. Both ‘B’ and ‘C’ are correc

Last Answer : D. Both ‘B’ and ‘C’ are correct

Description : The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in ... locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug

Last Answer : B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally

Description : Which component of sulfasalazine is responsible for the therapeutic effect in rheumatoid arthritis: A. Intact sulfasalazine molecule B. Sulfapyridine C. 5–aminosalicylic acid D. Both ‘B’ and ‘C’

Last Answer : B. Sulfapyridine

Description : The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate

Last Answer : C. Codergocrine

Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Last Answer : D. They are the preferred drugs in advanced cases

Description : The following is true about entacapone except: A. It acts by inhibiting degradation of dopamine in the brain B. If prolongs the therapeutic effect of levodopacarbidopa in parkinsonism C. It can accentuate levodopa induced dyskinesias D. It can cause diarrhoea as a side effec

Last Answer : A. It acts by inhibiting degradation of dopamine in the brain

Description : The primary action by which entacapone and tolcapone enhance the therapeutic effect of levodopa-carbidopa in parkinsonism is: A. Inhibition of levodopa methylation in the liver B. Inhibition of ... of dopamine in the brain D. Facilitation of active transport of levodopa across brain capillaries

Last Answer : A. Inhibition of levodopa methylation in the liver

Description : Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. ... its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

Last Answer : C. Used alone, its effective doses produce intolerable side effect

Description : The drug which abolishes the therapeutic effect of levodopa in parkinsonism, but not that of levodopacarbidopa combination is: A. Metoclopramide B. Pyridoxine C. Chlorpromazine D. Isoniazid

Last Answer : B. Pyridoxine

Description : The site of action of miotics for therapeutic effect in angle closure glaucoma is: A. Canal of Schlemm B. Ciliary body C. Ciliary muscle D. Sphincter pupillae muscle

Last Answer : D. Sphincter pupillae muscle

Description : When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action

Last Answer : C. Therapeutic window phenomenon

Description : The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation ... active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro

Last Answer : C. Heparin is the physiologically active circulating anticoagulant