Choose the correct statement about use of gold sod. thiomalate in rheumatoid arthritis: A. It affords more rapid symptomatic relief than NSAIDs B. The NSAIDs therapy is discontinued when it is started C. It is used as an alternative to corticosteroids D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed

Choose the correct statement about use of gold sod. thiomalate in rheumatoid arthritis: A. It affords more rapid symptomatic relief than NSAIDs B. The NSAIDs therapy is discontinued when it is started C. It is used as an alternative to corticosteroids D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed
by

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Answer :

D. It is used only in severe cases when other diseases modifying antirheumatic drugs have failed
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The following antirheumatic drug affords symptomatic relief but does not bring about remission in rheumatoid arthritis: A. Gold sodium thiomalate B. Prednisolone C. Hydroxychloroquine D. Leflunomide

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Last Answer : B. Prednisolone

Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive disease C. Only when NSAIDs fail to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication

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Last Answer : B. Along with NSAIDs in patients with progressive disease

The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in severe heart failure over and above that afforded by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief

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Among the disease modifying antirheumatic drugs, fastest symptom relief is obtained with: A. Auranofin B. Hydroxychloroquine C. Sulfasalazine D. Methotrexate

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What is true of acyclovir treatment of genital herpes simplex: A. Topical treatment affords symptomatic relief in primary as well as recurrent disease B. Oral therapy for 10 days affords symptomatic relief as well as prevents recurrences C. Oral therapy for 10 days affords symptomatic relief but does not prevent recurrences D. Continuous long-term topical therapy is recommended to prevent recurrences

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Last Answer : C. Oral therapy for 10 days affords symptomatic relief but does not prevent recurrences

Choose the correct statement(s) about metronidazole: A. It is a first line drug for amoebic dysentery as well as amoebic liver abscess B. It affords the most rapid symptom relief in amoebic dysentery C. It is the most effective drug in eradicating amoebic cysts from the colon D. All of the above

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What is true of disease modifying antirheumatic drugs: A. Their beneficial effect is manifest only after 1-3 months of therapy B. The disease does not recurr once they induce remission C. They are to be used life long D. Concurrent use of more than one disease modifying drug is not recommended

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Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. Serum lithium levels are lowered by concurrent administration of NSAIDs D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

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Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit

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Select the drug which affords faster and greater symptomatic relief in benign hypertrophy of prostate: A. Terazosin B. Desmopressin C. Finasteride D. Sildenafi

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Last Answer : A. Terazosin

The following is not a valid indication for parenteral iron therapy: A. Inadequate response to oral iron due to patient noncompliance B. Anaemia during pregnancy C. Severe anaemia associated with chronic bleeding D. Anaemia in a patient of active rheumatoid arthritis

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Which of the following is a reserve drug but not a disease modifying drug in rheumatoid arthritis: A. Chloroquine B. Sulfasalazine C. Prednisolone D. Methotrexate

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Last Answer : C. Prednisolone

Choose the correct statement(s) about auranofin: A. It is an orally active gold compound B. It is equally effective but less toxic than injected gold-sodium-thiomalate C. Its major adverse effect is dermatitis D. All of the above are correct

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Select the correct statement abut donepezil: A. It is a topical carbonic anhydrase inhibitor used in glaucoma B. It is a catechol-'O'-methyl transferase inhibitor used as adjuvant in parkinson's disease C. It is a cerebroselective anticholinesterase that affords symptomatic improvement in Alzheimer's disease D. It is a synthetic cannabinoid with antiemetic property

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Choose the correct statement about use of βadrenergic blockers in CHF: A. All β blockers are equally effective in CHF B. They are used as alternative to conventional therapy with ACE inhibitors ± digitalis/ diuretic C. They are most useful in mild to moderate cases with systolic dysfunction due to dilated cardiomyopathy D. They are indicated only in asymptomatic left ventricular dysfunction

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Eradication of H.pylori along with gastric antisecretory drugs affords the following benefit(s): A. Faster relief of ulcer pain B. Faster ulcer healing C. Reduced chance of ulcer relapse D. Both ‘B’ and ‘C’ are correct

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Which of the following is a disease modifying antirheumatic drug whose active metabolite inhibits the enzyme dihydro-orotate dehydrogenase: A. Leflunomide B. Nimesulide C. Sulfasalazine D. Colchicine

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Choose the correct statement about topical NSAID preparations: A. They produce high drug levels in the blood by avoiding hepatic first pass metabolism B. They produce high drug levels in the subjacent muscle and joint tissues upto a depth/distance of 10 cm from the site of application C. They elicit symptomatic relief in soft tissue rheumatism mainly by a strong placebo effect D. Interindividual variability in clinical response to these preparations is minimal

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Which of the following is a selective α1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin

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Which of the following is a selective α 1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin

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Corticosteroid therapy is practically mandatory in the following condition: A. Septic shock B. Renal transplant C. Rheumatoid arthritis D. Ulcerative colitis

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Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment of migraine attacks C. Use of ergot alkaloids is restricted to severe or resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

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Choose the correct statement about H2 receptor blockers: A. They are the most efficacious drugs in inhibiting gastric acid secretion B. They cause fastest healing of duodenal ulcers C. They prevent stress ulcers in the stomach D. They afford most prompt relief of ulcer pain

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4 Choose the correct statement about the role of opioid antimotility drugs in the management of diarrhoeas: A. They are used to control diarrhoea irrespective of its etiology B. They should be used only as a short-term measure after ensuring that enteroinvasive organisms are not involved C. They are used as adjuvants to antimicrobial therapy of diarrhoea D. They are the drugs of choice in irritable bowel syndrome diarrhoea

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ystemic corticosteroid therapy is not used routinely and is reserved only for severe cases of: A. Exfoliative dermatitis B. Posterior uveitis C. Acute rheumatic fever D. Hodgkin’s disease

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Compared to H2 blockers, omeprazole affords the following: A. Faster relief of ulcer pain B. Faster healing of duodenal ulcer C. Higher efficacy in healing reflux esophagitis D. All of the above

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Choose the correct statement about trimetazidine: A. It is a novel calcium channel blocker B. It improves tissue perfusion by modifying rheological property of blood C. It is an antianginal drug which acts by nonhaemodynamic mechanisms D. Both 'A' and 'B' are correct

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After chronic systemic therapy, withdrawal of corticosteroids should be gradual because: A. Corticosteroids produce psychological dependence B. Abrupt withdrawal may reactivate the underlying disease C. Abrupt withdrawal produces rebound hypertension D. All of the above are correct

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Beneficial effect/effects of diuretics in CHF patients include the following: A. Symptomatic relief B. Regression of pathological changes C. Prolongation of life expectancy D. Both ‘A’ and ‘C’

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Which of the following is/are acceptable reasons for the transfusion of red blood cells based on currently available data? A. Rapid, acute blood loss with unstable vital signs but no available hematocrit or hemoglobin determination. B. Symptomatic anemia: orthostatic hypotension, severe tachycardia (greater than 120 beats per minute), evidence of myocardial ischemia, including angina. C. To increase wound healing. D. A hematocrit of 26% in an otherwise stable, asymptomatic patient.

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Anti-HIV drug therapy is recommended in the following category of HIV exposed subjects: A. HIV positive symptomatic patients with opportunistic infections B. HIV positive asymptomatic subjects with CD4 cell count more than 400/μl C. HIV positive asymptomatic subjects with CD4 cell count less than 200/μl D. Both 'A' and 'C

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Mesalazine (coated 5-amino salicylic acid) differs from sulfasalazine in that: A. It is more effective in ulcerative colitis B. It produces less adverse effect C. It has no therapeutic effect in rheumatoid arthritis D. Both ‘B’ and ‘C’ are correc

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Used as a remission inducing agent in rheumatoid arthritis, hydroxychloroquine: A. Is more effective than chloroquine B. Produces a lower incidence of retinal damage than chloroquine C. Is more effective and more toxic than gold D. Both ‘A’ and ‘B’ are correct

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Last Answer : B. Produces a lower incidence of retinal damage than chloroquine

What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

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Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition

Leukotriene antagonists are used in bronchial asthma: A. For terminating acute attacks B. As monotherapy in place of β2 agonists C. As adjuvants to β2 agonists for avoiding corticosteroids D. As nebulized powder in refractory cases

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Last Answer : C. As adjuvants to β2 agonists for avoiding corticosteroids

Which component of sulfasalazine is responsible for the therapeutic effect in rheumatoid arthritis: A. Intact sulfasalazine molecule B. Sulfapyridine C. 5–aminosalicylic acid D. Both ‘B’ and ‘C’

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Last Answer : B. Sulfapyridine

Most skin conditions related to HIV disease may be helped primarily by a) highly active antiretroviral therapy (HAART). The goals of all HIV-related conditions include improvement of CD4 count and lowering of viral load. Initiation of HAART (highly active antiretroviral therapy) will help improve most skin conditions related to HIV disease. Symptomatic relief will be required until the skin condition improves.

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Last Answer : a) highly active antiretroviral therapy (HAART). The goals of all HIV-related conditions include improvement of CD4 count and lowering of viral load. Initiation of HAART (highly active ... conditions related to HIV disease. Symptomatic relief will be required until the skin condition improves.

Propranolol is used in hyperthyroidism: A. As short-term symptomatic therapy till effect of carbimazole develops B. As long-term therapy after subtotal thyroidectomy C. In patients not responding to carbimazole D. To potentiate the effect of radioactive iodine

Description : Propranolol is used in hyperthyroidism: A. As short-term symptomatic therapy till effect of carbimazole develops B. As long-term therapy after subtotal thyroidectomy C. In patients not responding to carbimazole D. To potentiate the effect of radioactive iodine

Last Answer : A. As short-term symptomatic therapy till effect of carbimazole develops

Which of the following drugs can afford both haemodynamic improvement as well as disease modifying benefits in CHF: A. Furosemide B. Milrinone C. Losartan D. Digoxin

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In an asthma patient treated with systemic corticosteroids, bronchodilator drugs: A. Are not needed B. Are contraindicated C. May be used on ‘as and when required’ basis D. Are ineffective

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Last Answer : C. May be used on ‘as and when required’ basis

Three medications referred to as the ‘ABC drugs’ are currently the main pharmacological therapy for multiple sclerosis. Which of the following statements reflects information to be included in patient teaching? a) Flu-like symptoms can be controlled with nonsteroidal antiinflammatory drugs (NSAIDs) and usually resolve after a few months of therapy. Seventy-five percent of patients taking one of the interferons experience flu-like symptoms that can be controlled with NSAIDS and usually resolve after a few months of therapy.

Description : Three medications referred to as the ABC drugs' are currently the main pharmacological therapy for multiple sclerosis. Which of the following statements reflects information to be included in patient ... on an empty stomach. Glatiramer acetate is administed by intramuscular injection once a week.

Last Answer : a) Flu-like symptoms can be controlled with nonsteroidal antiinflammatory drugs (NSAIDs) and usually resolve after a few months of therapy. Seventy-five percent of patients taking one of the ... symptoms that can be controlled with NSAIDS and usually resolve after a few months of therapy.

The primary objective for designing drugs that selectively inhibit COX – 2 is to (a) Decrease the risk of nephrotoxicity (b) Improve anti-inflammatory effectiveness (c) Lower the risk of gastrointestinal toxicity (d) Reduce the cost of treatment of rheumatoid arthritis (e) Selectively decrease thromboxane A2 without effects on other eicosanoids

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Last Answer : Ans: C