Description : Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity: A. Lignocaine B. Quinidine C. Verapamil D. Amiodarone
Last Answer : A. Lignocaine
Description : The following prokinetic drug has been implicated in causing serious ventricular arrhythmias, particularly in patients concurrently receiving erythromycin or ketoconazole: A. Domperidone B. Cisapride C. Mosapride D. Metoclopramide
Last Answer : B. Cisapride
Description : Which of the following adverse drug reactions is due to a specific genetic abnormality: A. Tetracycline induced sunburn like skin lesions B. Quinidine induced thrombocytopenia C. Metoclopramide induced muscle dystonia D. Primaquine induced massive haemolysis
Last Answer : D. Primaquine induced massive haemolysis
Description : The following drug is preferred for termination as well as prophylaxis of paroxysmal supraventricular tachycardia: A. Digoxin B. Verapamil C. Propranolol D. Quinidine
Last Answer : B. Verapami
Description : The following drug/drugs should not be used to treat tricyclic antidepressant drug poisoning: A. Quinidine B. Digoxin C. Atropine D. All of the above
Last Answer : D. All of the above
Description : Which of the following is the drug of choice in treating suicidal overdose of digitoxin ? (a) Digoxin antibodies (b) Lidocaine (c) Magnesium (d) Potassium (e) Quinidine
Last Answer : Ans: A
Description : Which of the following situations constitutes an added risk of digoxin toxicity ? (a) Starting administration of captopril (b) Starting administration of quinidine (c) Hyperkalemia (d) Hypermagnesemia (e) Hypocalcemia
Last Answer : Ans: B
Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy
Last Answer : C. It does not concurrently enhance noradrenaline release
Description : Infusion of potassium chloride is indicated in digitalis toxicity when the manifestation(s) is/are: A. Vomiting, hyperapnoea and visual disturbance B. Pulsus bigeminus with heart rate 110/min ... accidentally ingested 10 digoxin tablets D. 2:1 A-V block with occasional ventricular extrasystoles
Last Answer : B. Pulsus bigeminus with heart rate 110/min in a patient on maintenance digoxin therapy
Description : Among all cardiac glycosides, digoxin is the most commonly used, because: A. It is the most potent and fastest acting glycoside B. It has the highest and most consistent oral ... so that dose adjustments are possible every 2-3 days and toxicity abates rather rapidly after discontinuatio
Last Answer : D. It has intermediate plasma half life so that dose adjustments are possible every 2-3 days and toxicity abates rather rapidly after discontinuatio
Description : Which of the following drugs can precipitate hypoglycaemia if given to a diabetic controlled with a sulfonylurea drug: A. Phenobarbitone B. Chloramphenicol C. Rifampicin D. Oral contraceptive
Last Answer : . Chloramphenicol
Description : A manic patient has been brought to the hospital with nonstop talking, singing, uncontrolable behaviour and apparent loss of contact with reality. Which of the following is the most appropriate drug ... control of his symptoms: A. Lithium carbonate B. Phenobarbitone C. Haloperidol D. Valproic acid
Last Answer : C. Haloperidol
Description : The preferred drug for status epilepticus is: A. Intravenous diazepam B. Intravenous phenytoin sodium C. Intramuscular phenobarbitone D. Rectal diazepam
Last Answer : A. Intravenous diazepam
Description : A 3-year-old boy gets seizures whenever he develops fever. Which is the most appropriate strategy so that he does not develop febrile convulsions: A. Treat fever with paracetamol and ... Continuous diazepam prophylaxis for 3 years D. Intermittent diazepam prophylaxis started at the onset of fever
Last Answer : D. Intermittent diazepam prophylaxis started at the onset of fever
Description : The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate
Last Answer : C. Rectal diazepam
Description : The following antiepileptic drug raises pentylene tetrazol seizure threshold but does not modify maximal electroshock seizures: A. Ethosuximide B. Carbamazepine C. Primidone D. Phenobarbitone
Last Answer : A. Ethosuximide
Description : Select the antiepileptic drug that is effective in manicdepressive illness as well: A. Ethosuccimide B. Primidone C. Phenobarbitone D. Carbamazepine
Last Answer : D. Carbamazepine
Description : The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide
Last Answer : B. Phenobarbitone
Description : ntacids administered concurrently reduce efficacy of the following antipeptic ulcer drug: A. Cimetidine B. Colloidal bismuth C. Sucralfate D. Pirenzepine
Last Answer : C. Sucralfate
Description : Select the drug(s) which afford(s) relief in gastroesophageal reflux by increasing lower esophageal sphincter tone and promoting gastric emptying, but without affecting acidity of gastric contents: A. Sodium alginate B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C
Last Answer : D. Both ‘B’ and ‘C’
Description : A patient returning from dinner party meets with road accident and has to be urgently operated upon under general anaesthesia. Which drug can be injected intramuscularly to hasten his gastric emptying: A. Methylpolysiloxane B. Promethazine C. Metoclopramide D. Apomorphine
Last Answer : C. Metoclopramide
Description : The progastrokinetic action of the following drug(s) is attenuated by atropine: A. Domperidone B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C’
Last Answer : D. Both ‘B’ and ‘C
Description : Which prokinetic drug(s) produce(s) extrapyramidal side effects: A. Metoclopramide B. Cisapride C. Domperidone D. All of the above
Last Answer : A. Metoclopramide
Description : Select the prokinetic-antiemetic drug which at relatively higher doses blocks both dopamine D2 as well as 5-HT3 receptors and enhances acetylcholine release from myenteric neurones: A. Cisapride B. Prochlorperazine C. Metoclopramide D. Domperidon
Description : The drug which abolishes the therapeutic effect of levodopa in parkinsonism, but not that of levodopacarbidopa combination is: A. Metoclopramide B. Pyridoxine C. Chlorpromazine D. Isoniazid
Last Answer : B. Pyridoxine
Description : Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem
Last Answer : B. Amiodarone
Description : The following antiarrhythmic drug has the most prominent anticholinergic action: A. Disopyramide B. Quinidine C. Procainamide D. Lignocaine
Last Answer : A. Disopyramide
Description : The antiarrhythmic drug which decreases both rate of depolarization (phase 0) as well as rate of repolarization (phase 3) of myocardial fibres is: A. Lignocaine B. Propranolol C. Quinidine D. Verapamil
Last Answer : C. Quinidine
Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin
Last Answer : B. Warfarin
Description : The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin
Last Answer : B. Adenosine
Description : The following drug is used for short-term control of emergency heart failure, but not for long-term treatment of congestive heart failure: A. Digoxin B. Ramipril C. Dobutamine D. Spironolactone
Last Answer : C. Dobutamine
Description : The following drug can relieve symptoms of CHF but does not retard disease progression or prolong survival: A. Digoxin B. Carvedilol C. Spironolactone D. Ramipril
Last Answer : A. Digoxin
Description : The following drug has been demonstrated to retard progression of left ventricular dysfunction and prolong survival of congestive heart failure patients: A. Digoxin B. Furosemide C. Enalapril D. Amrinone
Last Answer : C. Enalapril
Description : The following drug increases cardiac output in congestive heart failure without having any direct myocardial action: A. Captopril B. Digoxin C. Amrinone D. Dobutamine
Last Answer : A. Captopril
Description : The following drug can cause rickets in children by interfering with vitamin D action: A. Tetracycline B. Digoxin C. Phenytoin D. Ciprofloxacin
Last Answer : C. Phenytoin
Description : A drug which is generally administered in standard doses without the need for dose individualization is: A. Insulin B. Mebendazole C. Prednisolone D. Digoxin
Last Answer : B. Mebendazole
Description : Thioguanine differs from mercaptopurine in that: A. It is not metabolized by xanthine oxidase B. It does not cause hyperuricemia C. Its dose need not be reduced when allopurinol is given concurrently D. Both ‘A’ and ‘C’ are correc
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : Recognized adverse effects of quinidine include which one of the following? (a) Cinchonism (b) Constipation (c) Lupus erythematosus (d) Increase in digoxin clearance (e) Precipitation of hyperthyroidism
Description : Which of the following drugs is preferred for termination of paroxysmal supraventricular tachycardia (a) Digoxin (b) Quinidine (c) Propranolol (d) Verapamil
Last Answer : Ans: D
Description : Which one of the following drugs predictably prolongs the PR interval and increases cardiac contractility? (a) Digoxin (b) Lidocaine (c) Propranolol (d) Quinidine (e) Verapamil
Description : Which one of the following drugs increase digoxin plasma concentration by a pharmacokinetic mechanism? (a) Captopril (b) Hydrochorothiazide (c) Lidocaine (d) Quinidine (e) Sulfasalazine
Description : Prazosin is an effective antihypertensive while nonselective a adrenergic blockers are not because (a) It is the only orally active a blocker (b) It improves plasma lipid profile (c) It does not concurrently enhance noradrenaline release (d) It improves urine flow in males with prostatic hypertrophy
Last Answer : Ans: C
Description : Methotrexate has the following attributes except: A. It is cell cycle specific and kills cells in the S phase B. Its toxicity primarily affects bone marrow and epithelial structures C. Folic acid reverses its toxic effects D. It is the drug of choice for choriocarcinoma
Last Answer : C. Folic acid reverses its toxic effects
Description : The following drug of abuse is a hallucinogen: A. Cocaine B. Cannabis C. Heroin D. Methaqualone (p. 403) 31.1 Which of the following is a selective MAO-B inhibitor: A. Selegiline
Last Answer : B. Cannabis
Description : The antipsychotic drug most likely to cause ocular toxicity on long-term use is: A. Thioridazine B. Haloperidol C. Flupenthixol D. Pimozide
Last Answer : A. Thioridazine
Description : Drug cumulation is the basis of organ toxicity of the following drug when used for prolonged periods: A. Prednisolone B. Chloroquine C. Aspirin D. Hydralazine
Last Answer : B. Chloroquine
Description : Digitalis toxicity is enhanced by co-administration of (A) Potassium (B) Quinidine (C) Diuretics (D) Antacids
Last Answer : Ans. B & C
Description : Biological response modifiers like GM-CSF are used in conjunction with anticancer drugs for the following purpose(s): A. To enhance antitumour activity of the drug B. To prevent hypersensitivity reactions to ... . To hasten recovery from drug induced myelosuppression D. Both A' and C' are correct
Last Answer : C. To hasten recovery from drug induced myelosuppressio