Description : Hypothyroidism is a possible consequence of prolonged therapy with (a) Procainamide (b) Mexiletine (c) Sotalol (d) Amiodarone
Last Answer : Ans: D
Description : The following antiarrhythmic drug accumulates in the body for a very long time: A. Procainamide B. Mexiletine C. Bretylium D. Amiodarone
Last Answer : D. Amiodarone
Description : Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem
Last Answer : B. Amiodarone
Description : Which of the following is the drug of choice for management of cardiac arrhythmias that occur in digitalis toxicity? (a) Amiodarone (b) Lidocaine (c) Propranolol (d) Sotalol (e) Prazosin
Last Answer : Ans: B
Description : Which of the following is an orally active drug that blocks sodium channels and decreases action potential duration? (a) Adenosine (b) Amiodarone (c) Disopyramide (d) Esmolol (e) Mexiletine
Last Answer : Ans: E
Description : The following strategy will promote rather than curb emergence of antibiotic resistant micro-organisms: A. Whenever possible use broad spectrum antibiotics B. Prefer a narrow spectrum ... Prefer short and intensive courses of antibiotics D. Use antibiotic combinations for prolonged therapy
Last Answer : A. Whenever possible use broad spectrum antibiotics
Description : Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in steatorrhoea and loose motions: A. Ampicillin B. Tetracycline C. Neomycin D. Nystatin
Last Answer : C. Neomycin
Description : What is true of drug therapy of typhoid fever: A. Combination of chloramphenicol with ciprofloxacin is superior to either drug alone B. Ceftriaxone (i.v.) is one of the fastest acting ... C. Prolonged treatment with chloramphenicol eradicates typhoid carrier state D. All of the above are correct
Last Answer : B. Ceftriaxone (i.v.) is one of the fastest acting and most dependable treatment
Description : Prolonged lithium therapy can cause: A. Diabetes mellitus B. Goiter C. Parkinsonism D. Gout
Last Answer : B. Goiter
Description : Prolonged testosterone therapy can cause: A. Hypertrophy of seminiferous tubules of testes B. Hypertrophy of interstitial cells of testes C. Atrophy of interstitial cells of testes D. Both ‘A’ and ‘B’ are correct
Last Answer : C. Atrophy of interstitial cells of testes
Description : n addition to counteracting potassium loss, triamterene also opposes the following consequence of thiazide/furosemide therapy: A. Hyperuricaemia B. Rise in plasma LDL-cholesterol C. Magnesium loss D. Both ‘A’ and ‘C’ are correct
Last Answer : C. Magnesium loss
Description : The following is an orally active lignocaine congener used for both acute as well as chronic ventricular arrhythmias: A. Mexiletine B. Flecainide C. Moricizine D. Propafenone
Last Answer : A. Mexiletine
Description : Which of the following drugs depresses automaticity of SA node as well as ectopic foci, abbreviates action potential duration of Purkinje fibres, and slows atrioventricular conduction: A. Propranolol B. Lignocaine C. Procainamide D. Bretylium
Last Answer : A. Propranolol
Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are corre
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Last Answer : A. Disopyramide
Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are correct
Description : The following antiarrhythmic drug has the most prominent anticholinergic action: A. Disopyramide B. Quinidine C. Procainamide D. Lignocaine
Description : Select the drug which is used by intravenous infusion for emergency control of tachycardia and sudden rise in blood pressure: A. Amiodarone B. Lignocaine C. Esmolol D. Disopyramide
Last Answer : C. Esmolo
Description : Select the drug which is an ‘inodilator’ beneficial in refractory congestive heart failure: A. Nicorandil B. Amiodarone C. Amrinone D. Carvedilol
Last Answer : C. Amrinone
Description : Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity: A. Lignocaine B. Quinidine C. Verapamil D. Amiodarone
Last Answer : A. Lignocaine
Description : The most important drawback of radioactive iodine treatment of Grave’s disease is: A. Subsequent hypothyroidism in many patients B. Marked side effect for 1-2 weeks after treatment C. High cost D. Permanent cure cannot be achieved
Last Answer : A. Subsequent hypothyroidism in many patients
Description : n the treatment of hyperthyroidism, carbimazole has the following advantage over radioactive iodine: A. Cost of treatment is lower B. It is preferable in uncooperative patient C. It is better tolerated by the patients D. Hypothyroidism when induced is reversible
Last Answer : Hypothyroidism when induced is reversible
Description : The most reliable guide to adjustment of thyroxine dose in a patient of hypothyroidism is: A. Pulse rate B. Body weight C. Serum thyroxine level D. Serum TSH level
Last Answer : D. Serum TSH level
Description : 17.4 The most reliable guide to adjustment of thyroxine dose in a patient of hypothyroidism is: A. Pulse rate B. Body weight C. Serum thyroxine level D. Serum TSH level
Description : The effects of diethyl carbamazine citrate in filariasis include the following except: A. Rapid symptomatic relief in acute filarial attack B. Renders filarial patients noninfective to mosquitoes ... Prolonged treatment may achieve radical cure by killing adult filarial worms lodged in lymphatics
Last Answer : C. Prolonged treatment induces regression of filarial elephantiasis
Description : The following is true of levamisole except: A. A single dose cures over 90% cases of round worm infestation B. It is more effective against Necator americanus than against Ancylostoma duodenale C. It has immunomodulating action D. Its prolonged use causes severe reactions
Last Answer : B. It is more effective against Necator americanus than against Ancylostoma duodenale
Description : Prolonged use of the following drug has been implicated in the causation of subacute myelo-optic neuropathy (SMON): A. Diloxanide furoate B. Iodochlorhydroxyquin C. Emetine D. Furazolidone
Last Answer : B. Iodochlorhydroxyquin
Description : The antibacterial action of aminoglycoside antibiotics is characterized by: A. Concentration dependent rate of bacterial cell killing B. Concentration dependent prolonged postantibiotic effect C. More pronounced bactericidal effect in anaerobic medium D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Widespread and prolonged use of an antibiotic leads to emergence of drug resistant strains because antibiotics: A. Induce mutation in the bacteria B. Promote conjugation among bacteria C. Allow resistant strains to propagate preferentially D. All of the above
Last Answer : C. Allow resistant strains to propagate preferentially
Description : Which of the following purgatives undergoes enterohepatic circulation to produce prolonged action: A. Docusates B. Phenolphthalein C. Castor oil D. Mag. sulfate
Last Answer : B. Phenolphthalein
Description : Prolonged treatment with the following drug can promote dissolution of gallstones if the gall bladder is functional: A. Ursodeoxycholic acid B. Sodium taurocholate C. Sodium glycocholate D. Cholecystokinin
Last Answer : A. Ursodeoxycholic acid
Description : Choose the correct statement about colloidal bismuth subcitrate: A. It causes prolonged neutralization of gastric acid B. It has anti-H.pylori activity C. It relieves peptic ulcer pain promptly D. All of the above are correct
Last Answer : B. It has anti-H.pylori activity
Description : The following is true of proton pump inhibitors except: A. They are the most effective drugs for Zolinger Ellison syndrome B. Their prolonged use can cause atrophy of gastric mucosa C. They inhibit growth of H. pylori in stomach D. They have no effect on gastric motilit
Last Answer : B. Their prolonged use can cause atrophy of gastric mucosa
Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication
Last Answer : A. Both possess vitamin B3 activity
Description : In post-myocardial infarction and other high cardiovascular risk subjects but without hypertension or heart failure, prolonged ACE inhibitor medication has been found to: A. Increase the chances of sudden cardiac death ... Lower the risk of developing heart failure and diabetes D. Both B and C'
Last Answer : D. Both ‘B‘ and ‘C
Description : Prolonged painful erection of penis has been noted particularly as a side effect of: A. Doxepin B. Citalopram C. Bupropion D. Trazodone
Last Answer : D. Trazodone
Description : The following drug is routinely used in preanaesthetic medication for prolonged operations: A. Atropine B. Morphine C. Promethazine D. Ranitidine
Last Answer : D. Ranitidine
Description : The following is true of sevoflurane except: A. It induces anaesthesia rapidly B. It is nonpungent C. It produces prolonged postanaesthetic psychomotor impairment D. It is less potent than halothane
Last Answer : C. It produces prolonged postanaesthetic psychomotor impairment
Description : The most likely complication of prolonged use of nasal decongestant drops is: A. Atrophic rhinitis B. Hypertrophy of nasal mucosa C. Naso-pharyngeal moniliasis D. Blockage of eustachian tubes
Last Answer : A. Atrophic rhinitis
Description : Drug cumulation is the basis of organ toxicity of the following drug when used for prolonged periods: A. Prednisolone B. Chloroquine C. Aspirin D. Hydralazine
Last Answer : B. Chloroquine
Description : The typical response to intravenous injection of 5-HT in an anaesthetised animal is: A. Rise in BP B. Fall in BP C. Rise followed by brief fall in BP D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Last Answer : D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Description : hat is/are the consequence(s) of myocardial Na+ K+ ATPase inhibition by digoxin: A. Increased intracellular Na+ ion concentration B. Increased cytosolic Ca2+ ion concentration C. Increased intracellular K+ ion concentration D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Down regulation of receptors can occur as a consequence of: A. Continuous use of agonists B. Continuous use of antagonists C. Chronic use of CNS depressants D. Denervation
Last Answer : A. Continuous use of agonists
Description : Serum sodium level rises in all of the following except (A) Renal failure (B) Prolonged steroid therapy (C) Aldosteronism (D) Dehydration
Last Answer : Answer : A
Description : All the following conditions produce a real or functional deficiency of vitamin K except (A) Prolonged oral, broad spectrum antibiotic therapy (B) Total lack of red meat in the diet (C) The total lack of green leafy vegetables in the diet (D) Being a new born infant
Last Answer : Answer : B
Description : Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in statorrhoea and loose motions (a) Ampicillin (b) Tetracycline (c) Neomycin (d) Nystatin
Last Answer : Ans: C
Description : All of the following factors may increase the risk of nephrotoxicity from gentamicin therapy except (a) age over 70 years (b) prolonged courses of gentamicin therapy (c) concurrent amphotericin B therapy (d) trough gentamicin levels below 2 mg/ml (e) concurrent cisplatin therapy
Description : A 65 years-old woman arrived for dental therapy. The answered questionnaire shows that she is suffering from severe cirrhosis. The problem that can be anticipated in the routine dental ... oral infection D. Increased tendency to syncope E. Difficulty in achieving adequate local anaesthesia
Last Answer : B. Tendency towards prolonged haemorrhage
Description : Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol
Last Answer : D. Esmolol