answer:I don’t have a lot of information but I have been collaborating with a research team that studies neurovisceral disorders, and I have been surprised to learn how much the gut microbiota can influence general health. It sounds entirely plausible to me that your issues might be caused by a certain bacteria or group of bacteria and doctors just have no way to know which one and knock it out. And of course, there could be a different population of bacteria that normally keep the bad bacteria in check, and for some reason in your gut, the good bacteria don’t survive as well. So maybe the issues could be resolved either by antibiotics to get rid of the bad ones, or probiotics to help grow the bad ones? Have you had experiences with probiotics? Here’s a study that showed decreased inflammation in UC patients using probiotics, and another review that might be helpful. I see @Rarebear is here with actual expertise, so I will stop there :) I’m glad your antibiotics are helping!