True statements about p53 include: a. a protein coded by a tumour suppressor gene b. it suppresses mitosis c. it is important regulators of apoptosis d. all above

True statements about p53 include:
a. a protein coded by a tumour suppressor gene
b. it suppresses mitosis
c. it is important regulators of apoptosis
d. all above
by

1 Answer

Answer :

all above
by

Related questions

In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell proliferation? For example, many cancer cells carry two mutant copies of the gene that codes for a tumor suppressor protein named p53. What is the normal function of p53 that is lost when it is mutated?

Description : In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell ... protein named p53. What is the normal function of p53 that is lost when it is mutated?

Last Answer : Normally, p53 senses DNA damage and acts as a transcription factor for checkpoint control genes.

RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene

Description : RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene

Last Answer : Answer : A

P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these

Description : P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these

Last Answer : Answer : C

Which of the following findings is most useful for staging of a tumour C A. Presence of necrosis B. Presence of abnormal mitoses C. Presence of metastases D. Absence of apoptosis

Description : Which of the following findings is most useful for staging of a tumour C A. Presence of necrosis B. Presence of abnormal mitoses C. Presence of metastases D. Absence of apoptosis

Last Answer : Presence of metastases

Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) Attaching to promoter region and facilitating the binding of RNA polymerase holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Last Answer : Answer : D

Bacillus thuringiensis forms protein crystals which contain insecticidal protein. This protein (a) binds with epithelial cells of midgut of the insect pest ultimately killing it (b) is coded by several genes including the gene cry (c) is activated by acid pH of the foregut of the insect pest (d) does not kill the carrier bacterium which is itself resistant to this toxin.

Description : Bacillus thuringiensis forms protein crystals which contain insecticidal protein. This protein (a) binds with epithelial cells of midgut of the insect pest ultimately killing it (b) is coded by several ... pest (d) does not kill the carrier bacterium which is itself resistant to this toxin.

Last Answer : (a) binds with epithelial cells of midgut of the insect pest ultimately killing it

Management’s assertions in the financial statements are relevant to the audit process because: a. They provide evidence that auditors have prepared financial statements in accordance with GAAP b. They embody the audit procedures that will be performed by the audit engagement team. c. They include representations of financial statements in accordance with the applicable reporting criteria d. They relate to regulator’s expectations about audit results

Description : Management's assertions in the financial statements are relevant to the audit process because: a. They provide evidence that auditors have prepared financial statements in accordance with GAAP b ... with the applicable reporting criteria d. They relate to regulator's expectations about audit results

Last Answer : They include representations of financial statements in accordance with the applicable reporting criteria

Management’s assertions in the financial statements are relevant to the audit process because: a. They provide evidence that auditors have prepared financial statements in accordance with GAAP b. They embody the audit procedures that will be performed by the audit engagement team. c. They include representations of financial statements in accordance with the applicable reporting criteria d. They relate to regulator’s expectations about audit results

Description : Management's assertions in the financial statements are relevant to the audit process because: a. They provide evidence that auditors have prepared financial statements in accordance with GAAP b ... with the applicable reporting criteria d. They relate to regulator's expectations about audit results

Last Answer : They include representations of financial statements in accordance with the applicable reporting criteria

The phenomenon, in which an allele of one gene suppresses the activity of an allele of another gene, is known as (a) epistasis (b) dominance (c) suppression (d) inactivation

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Last Answer : (a) epistasis

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Description : Antibody diversity results from a. Apoptosis. b. Antigenic shift. c. Somatic recombination. d. Complement binding.

Last Answer : c. Somatic recombination.

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Last Answer : Inactivation of a translational elongation factor

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Description : The role of the M cell is to A- .trap virus in mucus and prevent entry B- induce apoptosis in virus-infected small intestinal epithelia cells C- pass bacteria or virus to underlying macrophages for ... and presentation of antigen D- they use their cilia to propel mucus out of the small intestine

Last Answer : pass bacteria or virus to underlying macrophages for processing and presentation of antigen

An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix of DNA by an enzyme known as DNA polymerase b. The initial product of DNA transcription is called heterogeneous nuclear RNA which codes directly for proteins c. After processing is complete, the mRNA is exported from the nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

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Last Answer : (c) interferon

On AC vessels, which of the following statements represents the most difficult problem involved in obtaining a DC potential suitable for use by computer components? A. A stepdown transformer is always required. B. Vessel vibrations affect the voltage source. C. The voltage must be rectified and made ripple free. D. Rectifiers cannot operate with voltage regulators.

Description : On AC vessels, which of the following statements represents the most difficult problem involved in obtaining a DC potential suitable for use by computer components? A. A stepdown transformer is ... voltage must be rectified and made ripple free. D. Rectifiers cannot operate with voltage regulators.

Last Answer : Answer: C

Which of the following finding is most important for grading of tumours? C A. Presence of tumour cells in the vascular spaces B. Level of invasion C. Microscopic pleomorphism of nuclei and the number of mitoses D. degree of metastasis

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Last Answer : Microscopic pleomorphism of nuclei and the number of mitoses

The following are true about antigen presenting cells (APC): a. Langerhan's cells are the antigen presenting cells of the epidermis b. CD8+ cells only recognize antigen presenting cells bearing MHC (major histocompatibility complex) class I c. tumour necrosis factor alpha (TNF ) can turn endothelial cells into antigen presenting cells d. all above

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Suppressor tRNAs can neutralize the effects of mutations in (A) Structural genes (B) Promoter regions (C) Enhancer elements(D) All of these

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A synthetic nucleotide analogue, used in organ transplantation as a suppressor of immunologic rejection of grafts is (A) Theophylline (B) Cytarabine (C) 4-Hydroxypyrazolopyrimidine (D) 6-Mercaptopurine

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CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

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CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

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Harmonic suppressor connected to an antenna. A. High pass filter B. Low pass filter C. Tank circuit D. M-derived filter

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Echo suppressor is detrimental to full duplex operation because (A) It disables one of the two pairs in a four-wire trunk line when a signal is detected on the other pair. (B) It enables one of the two pairs in a four-wire trunk line when a signal is detected on the other pair. (C) It activates both the pairs of a four-wire trunk line. (D) It is independent of line conditions.

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The suppressor grid is added to a tetrode to reduce what undesirable characteristic of tetrode operation?

Description : The suppressor grid is added to a tetrode to reduce what undesirable characteristic of tetrode operation?

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Which of the following sequence is correct? (i) An increase in body fluid volume `rarr` switch off the osmoreceptors `rarr` suppresses the ADH Release

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Presence of high amount of silicon in cast iron (A) Suppresses the decomposition of Fe3C (B) Increases the formation of graphite (C) Increases the contraction of the metal (D) Reduces its fluidity

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Combustion of pulverised fuel (A) Requires larger combustion chamber than rich gaseous fuel (B) In a metallurgical furnace does not contaminate the product in the furnace by ash from fuel (C) Suppresses the discharge of fine dust and grit into atmosphere (D) All (A), (B) and (C)

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Description : High endurance limit of carburised machine parts is because of the fact that carburisation (A) Suppresses any stress concentration produced in the parts (B) Enhances the yield point of the material (C) Introduces a compressive layer on the surface (D) Produces a better surface finish

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Which antileprotic drug suppresses lepra reaction and reversal reaction as well: A. Dapsone B. Rifampin C. Clofazimine D. Minocycline

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Description : The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in ... locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug

Last Answer : B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally

Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route

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Last Answer : B. It suppresses postoperative nausea and vomitin

Choose the correct statement about the use of propranolol in anxiety: A. Being nonsedative, it is the drug of choice in chronic anxiety states B. It suppresses the psychological component of anxiety C. It suppresses the autonomic manifestations of acutely stressful situations D. Both ‘B’ and ‘C’ are correct

Description : Choose the correct statement about the use of propranolol in anxiety: A. Being nonsedative, it is the drug of choice in chronic anxiety states B. It suppresses the psychological component of anxiety ... the autonomic manifestations of acutely stressful situations D. Both B' and C' are correct

Last Answer : C. It suppresses the autonomic manifestations of acutely stressful situations

Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures

Description : Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures

Last Answer : C. It is a broad spectrum antiepileptic drug

he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide

Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide

Last Answer : C. Sodium valproate

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Last Answer : C. It can disorganise sleep architecture

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Description : Progesterone administration: A. Suppresses onset of menstruation B. Induces watery cervical secretion C. Sensitizes the uterus to oxytocin D. Cornifies vaginal epithelium

Last Answer : A. Suppresses onset of menstruation

Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Description : Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Last Answer : B. Propranolol

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

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Last Answer : C. Noncompetitive antagonist

Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin therapy prevents granulomatous lesions and cardiac complications of acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer

Description : Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin ... acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer

Last Answer : B. Aspirin suppresses flushing attending large dose of nicotinic acid

Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Description : Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Last Answer : B. More potent α adrenergic blocking than β blocking activity

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Last Answer : C. Noncompetitive antagonist