MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
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MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : B

CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : A

CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : C

The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : B

T cells can recognise (A) Free antigens (B) Antigens bound to cells (C) Antigens bound to antibodies (D) Antigens bound to MHC proteins

Description : T cells can recognise (A) Free antigens (B) Antigens bound to cells (C) Antigens bound to antibodies (D) Antigens bound to MHC proteins

Last Answer : Answer : D

CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these

Description : CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these

Last Answer : Answer : D

The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents the virus infected cells to cytotoxic T lymphocytes d. HLA genes are found on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection

Description : The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents ... on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection

Last Answer : HLA class I antigens are expressed on all cells with nuclei

T cell receptors (or TCR) on CD4+ T cells A.recognize peptides not associated with MHC molecules B.recognize peptides associated with MHC class I molecules C.recognize peptides associated with MHC class II molecules D.are secreted out into the environment to bind antigens

Description : T cell receptors (or TCR) on CD4+ T cells A.recognize peptides not associated with MHC molecules  B.recognize peptides associated with MHC class I molecules  C.recognize peptides associated with MHC class II molecules  D.are secreted out into the environment to bind antigens

Last Answer : C.recognize peptides associated with MHC class II molecules

Which of the following is correct?A- All T Cells are CD4+ B- An epitope can have multiple antigens C- .T Cell receptors are generated by random assortment of gene cassettes D- .MHC Class II molecules are generated by random assortment of gene cassettes

Description : Which of the following is correct? A- All T Cells are CD4+ B- An epitope can have multiple antigens C- .T Cell receptors are generated by random assortment of gene cassettes D- .MHC Class II molecules are generated by random assortment of gene cassettes

Last Answer : .T Cell receptors are generated by random assortment of gene cassettes

cell receptors (or TCR) on CD4+ T cells A-recognize peptides not associated with MHC molecules B- recognize peptides associated with MHC class I moleculesC- recognize peptides associated with MHC class II molecules D- are secreted out into the environment to bind antigens

Description : cell receptors (or TCR) on CD4+ T cells A-recognize peptides not associated with MHC molecules B- recognize peptides associated with MHC class I moleculesC- recognize peptides associated with MHC class II molecules D- are secreted out into the environment to bind antigens

Last Answer : recognize peptides associated with MHC class II molecules

Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells

Description : Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells

Last Answer : Answer : B

The unique sets of proteins that present antigens on the surfaces of body cells are a. MHC proteins. b. Cytokines. c. Complement proteins. d. Immunoglobulins.

Description : The unique sets of proteins that present antigens on the surfaces of body cells are a. MHC proteins. b. Cytokines. c. Complement proteins. d. Immunoglobulins.

Last Answer : b. Cytokines.

Antigens that bind directly to MHC proteins without any processing are known as _____. a. epitopes b. haptens c. superantigens d. naïve cells

Description : Antigens that bind directly to MHC proteins without any processing are known as _____. a. epitopes b. haptens c. superantigens d. naïve cells

Last Answer : c. superantigens

What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils

Description : What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils

Last Answer : a. Suppressor T cells

MHC Class III proteins include (A) Immunoglobulins (B) Components of complement system (C) T cells receptors (D) CD4 and CD8 proteins

Description : MHC Class III proteins include (A) Immunoglobulins (B) Components of complement system (C) T cells receptors (D) CD4 and CD8 proteins

Last Answer : Answer : D

MHC class I proteins are present on the surface of (A) B cells only (B) T cells only (C) Macrophages only(D) All cells

Description : MHC class I proteins are present on the surface of (A) B cells only (B) T cells only (C) Macrophages only(D) All cells

Last Answer : Answer : D

The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI

Description : The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI

Last Answer : a. CD8. CD4

Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.

Description : Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.

Last Answer : c. Cytotoxic T cells.

The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the humoral immune response is/are correct? a. Helper T lymphocytes stimulate B lymphocytes through secretion of cytokines such as interleukin 4 and 6 b. A number of cells can aid in presenting the antigen to the helper T cell including B lymphocytes and macrophages c. All antigens require coordinated efforts of the various cellular components of the immune system d. An antigen must be a living microorganism

Description : The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the ... various cellular components of the immune system d. An antigen must be a living microorganism

Last Answer : Answer: a, b Stimulation of the immune system occurs after a variety of antigen-presenting cells (B lymphocytes, macrophages, dendritic cells, and Langerhans cells) act to engulf ... polysaccharides), most antigens require coordinated efforts of the various cellular components of the immune system

MHC class II proteins are present on the surface of (A) All cells (B) B lymphocytes only (C) Macrophages only (D) Macrophages and B lymphocytes

Description : MHC class II proteins are present on the surface of (A) All cells (B) B lymphocytes only (C) Macrophages only (D) Macrophages and B lymphocytes

Last Answer : Answer : D

. MHC class I proteins would be found on___________ whereas MHC class II proteins would be found on_____________ a. Nucleated Cells; Plasma Cells b. Nucleated Cells; Macrophages c. Dendritic Cells; Neutrophils d. Only White Blood Cells; Red Blood Cells

Description : . MHC class I proteins would be found on___________ whereas MHC class II proteins would be found on_____________ a. Nucleated Cells; Plasma Cells b. Nucleated Cells; Macrophages c. Dendritic Cells; Neutrophils d. Only White Blood Cells; Red Blood Cells

Last Answer : b. Nucleated Cells; Macrophages

Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Description : Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Last Answer : b. perforin and granzymes

Booster immunizations are used to raise the antibody level by stimulating the _____ cells to induce the secondary antibody response. a. helper T b. B c. memory d. plasma

Description : Booster immunizations are used to raise the antibody level by stimulating the _____ cells to induce the secondary antibody response. a. helper T b. B c. memory d. plasma

Last Answer : c. memory

_____ T cells prevent autoreactive T cells from attacking self. a. Memory b. Helper c. Regulatory d. Effector

Description : _____ T cells prevent autoreactive T cells from attacking self. a. Memory b. Helper c. Regulatory d. Effector

Last Answer : c. Regulatory

In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell proliferation? For example, many cancer cells carry two mutant copies of the gene that codes for a tumor suppressor protein named p53. What is the normal function of p53 that is lost when it is mutated?

Description : In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell ... protein named p53. What is the normal function of p53 that is lost when it is mutated?

Last Answer : Normally, p53 senses DNA damage and acts as a transcription factor for checkpoint control genes.

Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor

Description : Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor

Last Answer : Answer : B

Helper T cells release all the following except (A) Interleukins (B) Colony stimulating factors (C) Perforins (D) Tumour necrosis factor

Description : Helper T cells release all the following except (A) Interleukins (B) Colony stimulating factors (C) Perforins (D) Tumour necrosis factor

Last Answer : Answer : C

Helper T cells release (A) Interleukins (B) Colony stimulating factors (C) Tumour necrosis factor (D) All of these

Description : Helper T cells release (A) Interleukins (B) Colony stimulating factors (C) Tumour necrosis factor (D) All of these

Last Answer : Answer : B

MHC proteins are unique to (A) Each cell (B) Each organ (C) Each individual (D) Each species

Description : MHC proteins are unique to (A) Each cell (B) Each organ (C) Each individual (D) Each species

Last Answer : Answer : C

The following are true about antigen presenting cells (APC): a. Langerhan's cells are the antigen presenting cells of the epidermis b. CD8+ cells only recognize antigen presenting cells bearing MHC (major histocompatibility complex) class I c. tumour necrosis factor alpha (TNF ) can turn endothelial cells into antigen presenting cells d. all above

Description : The following are true about antigen presenting cells (APC): a. Langerhan's cells are the antigen presenting cells of the epidermis b. CD8+ cells only recognize antigen presenting cells bearing ... necrosis factor alpha (TNF ) can turn endothelial cells into antigen presenting cells d. all above

Last Answer : all above

A high surface area to volume ratio in cells is important because it (a) Enables efficient transfer of wastes, nutrients and gases across the cell membrane (b) Prevents overproduction of cell proteins due to structural limitations (c) Allows many antigens on the surface for identification of self and non-self (d) Provides for better structural support to cope with external physical pressure

Description : A high surface area to volume ratio in cells is important because it (a) Enables efficient transfer of wastes, nutrients and gases across the cell membrane (b) Prevents overproduction of cell ... self and non-self (d) Provides for better structural support to cope with external physical pressure

Last Answer : Ans:(a)

The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells

Description : The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells

Last Answer : c. TH2 Cell And NI( Cell

TH1 cells activatea. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.

Description : TH1 cells activate a. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.

Last Answer : d. Humoral immunity

Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9

Description : Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9

Last Answer : CD8

CD8 surface antigen is present in A- cytotoxic T cells B- .suppresssor T cells C- both (a) and (b) D- none of these

Description : CD8 surface antigen is present in A- cytotoxic T cells B- .suppresssor T cells C- both (a) and (b) D- none of these

Last Answer : both (a) and (b)

Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.

Description : Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection. b) are important in producing circulating antibodies. B cells are lymphocytes important in producing ... that decrease B-cell activity to a level at which the immune system is compatible with life.

Last Answer : a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.

Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies

Description : Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies

Last Answer : c) IgE mediated 

The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. Treatment with azidothymidine (AZD) appears to prolong survival when administered early in the disease c. Predisposition to infection in HIV infection is primarily due to reduction in the number of helper T cells d. Common infections in patients with AIDS are Pneumocystis, carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Description : The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. ... , carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Last Answer : Answer: b, c, d Acquired immunodeficiency syndrome (AIDS) is a syndrome caused by the human retrovirus (HIV-1) that infects T lymphocytes and causes severe immunosuppression. Individuals who ... to prolong survival when administered early in the course of disease and is considered routine therapy

Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells

Description : Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells

Last Answer : Polymorphonuclear leukocytes

At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) When HIV damages large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

Description : At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) ... large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

Last Answer : (c) When HIV damages large number of helper T  - lymphocytes

The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages

Description : The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages

Last Answer : ANSWER: B -- HELPER T CELLS

With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above

Description : With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above

Last Answer : all above

According to which theory is the given statement correct ? Statement. B and T cells having receptors for self antigens, undergo programmed cell death

Description : According to which theory is the given statement correct ? Statement. B and T cells having receptors for self antigens, undergo programmed cell death

Last Answer : According to which theory is the given statement correct ? Statement. B and T cells having ... C. Wear and tear throry D. Immunological theory

All forms of immunity depend on an exposure to antigens and a subsequent response by _____ cells. a. basophil b. neutrophil c. NK d. T

Description : All forms of immunity depend on an exposure to antigens and a subsequent response by _____ cells. a. basophil b. neutrophil c. NK d. T

Last Answer : d. T

The immune system normally discriminates between which types of antigens. a) B and T cells b) self and non-self c) humoral and cell-mediated d) primary and secondary

Description : The immune system normally discriminates between which types of antigens. a) B and T cells b) self and non-self c) humoral and cell-mediated d) primary and secondary

Last Answer : ANSWER: B -- SELF AND NON-SELF

Which of the following statements is false regarding B cells? A- B cells can undergo class switching and produce a different antibody type B- B one marrow stem cells migrate to the thymus and develop into B cells C- B cells synthesize antibodies and put them on their cell surface D- B cells that recognize high concentrations of antigens (self) in the absence of other signals

Description : Which of the following statements is false regarding B cells? A- B cells can undergo class switching and produce a different antibody type B- B one marrow stem cells migrate to the thymus and ... D- B cells that recognize high concentrations of antigens (self) in the absence of other signals

Last Answer : B one marrow stem cells migrate to the thymus and develop into B cells

TH2 cells bind to a. MHC-11/peptide complex on APC cells. b. B cell receptors. c. MHc-1/etid complex on infected cells. d. MHC-11/peptide complex on B cells.

Description : TH2 cells bind to a. MHC-11/peptide complex on APC cells. b. B cell receptors. c. MHc-1/etid complex on infected cells. d. MHC-11/peptide complex on B cells.

Last Answer : d. MHC-11/peptide complex on B cells.

Can substances other than proteins be antigens?

Description : Can substances other than proteins be antigens? 

Last Answer : Yes. Most antigens are proteins, but polysaccharides, certain lipids, and nucleic acids also can trigger immune reactions. Besides, some relatively simple organic chemicals and chemical groups can be specifically ... coupled with a protein. The latter in this case will be called a carrier. 

RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene

Description : RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene

Last Answer : Answer : A

P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these

Description : P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these

Last Answer : Answer : C