Description : Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine
Last Answer : B. More potent α adrenergic blocking than β blocking activity
Description : The most effective antimotion sickness drug suitable for short brisk journies is: A. Promethazine theoclate B. Cinnarizine C. Prochlorperazine D. Hyoscine
Last Answer : D. Hyoscine
Description : The most effective antiemetic for controlling cisplatin induced vomiting is: A. Prochlorperazine B. Ondansetron C. Metoclopramide D. Promethazine
Last Answer : B. Ondansetron
Description : In parkinsonian patients levodopa exerts the following effects except: A. Reduces skeletal muscle contractility B. Decreases muscle tone C. Increases locomotor activity D. Inhibits muscle tremor
Last Answer : A. Reduces skeletal muscle contractility
Description : Choose the correct statement about the use of propranolol in anxiety: A. Being nonsedative, it is the drug of choice in chronic anxiety states B. It suppresses the psychological component of anxiety ... the autonomic manifestations of acutely stressful situations D. Both B' and C' are correct
Last Answer : C. It suppresses the autonomic manifestations of acutely stressful situations
Description : Select the prokinetic-antiemetic drug which at relatively higher doses blocks both dopamine D2 as well as 5-HT3 receptors and enhances acetylcholine release from myenteric neurones: A. Cisapride B. Prochlorperazine C. Metoclopramide D. Domperidon
Last Answer : C. Metoclopramide
Description : Propranolol does not block the following action of adrenaline: A. Bronchodilatation B. Lipolysis C. Muscle tremor D. Mydriasis
Last Answer : D. Mydriasis
Description : Which one of the following drugs is most suitable for management of essential tremor in a patient who has pulmonary disease? (a) Diazepam (b) Levodopa (c) Metoprolol (d) Propranolol (e) Terbutaline
Last Answer : Ans: C
Description : A woman in the 28th week of pregnancy has developed pregnancy induced hypertension with a blood pressure reading of 150/100 mm Hg. Select the most appropriate antihypertensive drug for her: A. Furosemide B. Methyldopa C. Propranolol D. Captopril
Last Answer : B. Methyldopa
Description : Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil
Last Answer : D. Sildenafil
Description : Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures
Last Answer : C. It is a broad spectrum antiepileptic drug
Description : A patient returning from dinner party meets with road accident and has to be urgently operated upon under general anaesthesia. Which drug can be injected intramuscularly to hasten his gastric emptying: A. Methylpolysiloxane B. Promethazine C. Metoclopramide D. Apomorphine
Description : The following drug is routinely used in preanaesthetic medication for prolonged operations: A. Atropine B. Morphine C. Promethazine D. Ranitidine
Last Answer : D. Ranitidine
Description : Select the antihistaminic which blocks cardiac K+ channels when given in high doses or along with drugs that inhibit CYP3A4 isoenzyme: A. Chlorpheniramine B. Promethazine C. Astemizole D. Loratadine
Last Answer : C. Astemizole
Description : Which antileprotic drug suppresses lepra reaction and reversal reaction as well: A. Dapsone B. Rifampin C. Clofazimine D. Minocycline
Last Answer : C. Clofazimine
Description : The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in ... locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug
Last Answer : B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally
Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide
Last Answer : C. Sodium valproate
Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case
Last Answer : D. They are the preferred drugs in advanced cases
Description : Choose the phenothiazine compound which has selective labyrinthine suppressant action, is used for vomiting and vertigo, but not in schizophrenia: A. Triflupromazine B. Prochlorperazine C. Trifluoperazine D. Thioridazine
Last Answer : B. Prochlorperazine
Description : The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin
Last Answer : B. Adenosine
Description : The following is true of selegiline: A. It does not exert antiparkinsonian action unless combined with levodopa B. It overcomes the on-off ' effect in levodopa treated advanced parkinsonian ... D. At doses used in parkinsonism it does not interfere with peripheral metabolism of dietary amines
Last Answer : . At doses used in parkinsonism it does not interfere with peripheral metabolism of dietary amines
Description : Dexamphetamine produces an apparently paradoxical effect in: A. Addicts B. Athletes C. Parkinsonian patients D. Hyperkinetic children
Last Answer : Hyperkinetic children
Last Answer : . Hyperkinetic children
Description : Propranolol does not block the following action of adrenaline (a) Bronchodilation (b) Lipolysis (c) Muscle tremor (d) Mydriasis
Last Answer : Ans: D
Description : Propranolol is useful in all of the following except (a) Angina (b) Familial tremor (c) Hypertension (d) Idiopathic hypertrophic subaortic cardiomyopathy (e) Partial atrioverntricular heart block
Last Answer : Ans: E
Description : The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease
Last Answer : C. They are less likely to cause bradycardia
Description : The following antihypertensive drug has a favourable effect on plasma lipid profile: A. Prazosin B. Propranolol C. Hydrochlorothiazide D. Furosemide
Last Answer : A. Prazosin
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Last Answer : B. Enalapril
Description : Started within 4-6 hours of acute myocardial infarction, which of the following drug(s) can reduce the area of necrosis and the attendant mortality: A. Propranolol B. Glyceryl trinitrate C. Lignocaine D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : The following drug is preferred for termination as well as prophylaxis of paroxysmal supraventricular tachycardia: A. Digoxin B. Verapamil C. Propranolol D. Quinidine
Last Answer : B. Verapami
Description : The antiarrhythmic drug which decreases both rate of depolarization (phase 0) as well as rate of repolarization (phase 3) of myocardial fibres is: A. Lignocaine B. Propranolol C. Quinidine D. Verapamil
Last Answer : C. Quinidine
Description : Concurrent use of the following drug is likely to cause failure of oral contraception: A. Isoniazid B. Rifampicin C. Cimetidine D. Propranolol
Last Answer : C. Cimetidin
Description : A 60-year-old male presents with severe hyperthyroidism and multinodular goiter. It was decided to treat him with 131I. The most appropriate course of treatment would be: A. Immediate 131I dosing with no ... . Propranolol + Lugol's iodine for 2 weeks- 131I-continue Lugol's iodine for 2-3 months
Last Answer : C. Propranolol + carbimazole till severe thyrotoxicosis is controlled—1 week gap—131I— resume carbimazole after 1 week for 2-3 month
Description : Effect of alcohol on sleep has the following feature: A. It is a dependable hypnotic but is not prescribed because of abuse potential B. It consistently improves the quality of sleep C. It can disorganise sleep architecture D. It suppresses sleep apnoea
Last Answer : C. It can disorganise sleep architecture
Description : Cyclosporine has the following attributes except: A. It selectively suppresses humoral immunity without affecting cell mediated immunity B. It is more active as immunosuppressant when administered before antigen exposure ... It is not toxic to the bone marrow D. Its major toxicity is kidney damage
Last Answer : A. It selectively suppresses humoral immunity without affecting cell mediated immunity
Description : Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route
Last Answer : B. It suppresses postoperative nausea and vomitin
Description : Progesterone administration: A. Suppresses onset of menstruation B. Induces watery cervical secretion C. Sensitizes the uterus to oxytocin D. Cornifies vaginal epithelium
Last Answer : A. Suppresses onset of menstruation
Description : Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin ... acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer
Last Answer : B. Aspirin suppresses flushing attending large dose of nicotinic acid
Description : Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine
Last Answer : B. Propranolol
Description : Sodium valproate should be used with caution in young children because they are particularly at risk of developing the following adverse effect: A. Hepatitis B. Loss of hair C. Anorexia D. Tremor
Last Answer : A. Hepatitis
Description : Which of the following is a neuroglucopenic symptom of hypoglycaemia: A. Sweating B. Palpitation C. Tremor D. Abnormal behaviour
Last Answer : D. Type 2 diabetes patients not controlled by a biguanide drug
Description : Adrenergic β2 agonists produce muscle tremor by: A. Facilitating neuromuscular transmission B. Incomplete fusion of contractile response of individual fibres C. Enhanced firing of muscle spindles D. Both (b) and (c) are correct
Last Answer : D. Both (b) and (c) are correct
Description : The most prominent and dose related side effect of salbutamol is: A. Rise in blood pressure B. Muscle tremor C. Hyperglycaemia D. Central nervous system stimulation
Last Answer : B. Muscle tremor
Description : Select the drug that undergoes extensive first-pass metabolism in the liver: A. Phenobarbitone B. Propranolol C. Phenylbutazone D. Theophylline
Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist
Last Answer : C. Noncompetitive antagonist