CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

CD 4 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells
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CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : CD 8 is a transmembrane glycoprotein present in (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : C

MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : MHC Class II proteins, in conjunction with antigens, are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : B

MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : MHC class I proteins, in conjunction with antigens are recognised by (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : A

The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Description : The most abundant T cells are (A) Cytotoxic T cells (B) Helper T cells (C) Suppressor T cells (D) Memory T cells

Last Answer : Answer : B

CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these

Description : CD 3 complex and p 56lck proteins are present in (A) Cytotoxic T cells (B) Helper T cells (C) Both (A) and (B) (D) None of these

Last Answer : Answer : D

Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells

Description : Human immunodeficiency virus destroys (A) Cytotoxic T cells (B) Helper T cells (C) B cells (D) Plasma cells

Last Answer : Answer : B

What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils

Description : What type of immune cell may control IgE-mediated hypersensitivities? a. Suppressor T cells b. Plasma cells c. Cytotoxic T cells d. Neutrophils

Last Answer : a. Suppressor T cells

The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI

Description : The cytotoxic T cells have a_____ co-receptor while the helper T cells have a _____ co-receptor. a. CD8. CD4 b. CD4, CD8 c. MHCI, MHCII d. MHCII, MHCI

Last Answer : a. CD8. CD4

Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.

Description : Performs and granzymes are found in a. Helper T cells. b. Antigen-presenting cells. c. Cytotoxic T cells. d. B cells.

Last Answer : c. Cytotoxic T cells.

Booster immunizations are used to raise the antibody level by stimulating the _____ cells to induce the secondary antibody response. a. helper T b. B c. memory d. plasma

Description : Booster immunizations are used to raise the antibody level by stimulating the _____ cells to induce the secondary antibody response. a. helper T b. B c. memory d. plasma

Last Answer : c. memory

_____ T cells prevent autoreactive T cells from attacking self. a. Memory b. Helper c. Regulatory d. Effector

Description : _____ T cells prevent autoreactive T cells from attacking self. a. Memory b. Helper c. Regulatory d. Effector

Last Answer : c. Regulatory

CD8 surface antigen is present in A- cytotoxic T cells B- .suppresssor T cells C- both (a) and (b) D- none of these

Description : CD8 surface antigen is present in A- cytotoxic T cells B- .suppresssor T cells C- both (a) and (b) D- none of these

Last Answer : both (a) and (b)

Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor

Description : Cytotoxic T cells release (A) Perforins (B) Interleukins (C) Colony stimulating factors (D) Tumour necrosis factor

Last Answer : Answer : B

Helper T cells release all the following except (A) Interleukins (B) Colony stimulating factors (C) Perforins (D) Tumour necrosis factor

Description : Helper T cells release all the following except (A) Interleukins (B) Colony stimulating factors (C) Perforins (D) Tumour necrosis factor

Last Answer : Answer : C

Helper T cells release (A) Interleukins (B) Colony stimulating factors (C) Tumour necrosis factor (D) All of these

Description : Helper T cells release (A) Interleukins (B) Colony stimulating factors (C) Tumour necrosis factor (D) All of these

Last Answer : Answer : B

The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents the virus infected cells to cytotoxic T lymphocytes d. HLA genes are found on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection

Description : The following are true : a. the HLA proteins are found within the cytoplasm of the cells b. HLA class I antigens are expressed on all cells with nuclei c. HLA class II antigens presents ... on chromosome 6 e. HLA tissue typing is carried out in all forms of transplantation to prevent rejection

Last Answer : HLA class I antigens are expressed on all cells with nuclei

The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells

Description : The early response in asthma is due to activity. a. Cytotoxic T Cell b. Basophil c. TH2 Cell And NI( Cell d. Dendritic Cells

Last Answer : c. TH2 Cell And NI( Cell

Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Description : Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines

Last Answer : b. perforin and granzymes

TH1 cells activatea. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.

Description : TH1 cells activate a. B cells. b. Killing of pathogens in macrophages. c. Cytotoxic T cells. d. Humoral immunity.

Last Answer : d. Humoral immunity

Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9

Description : Cytotoxic T-cells can be recognized by which of the following cell surface marker? A- CD4 B- CD7 C- CD8 D- CD9

Last Answer : CD8

Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.

Description : Cytotoxic T cells a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection. b) are important in producing circulating antibodies. B cells are lymphocytes important in producing ... that decrease B-cell activity to a level at which the immune system is compatible with life.

Last Answer : a) lyse cells infected with virus. Cytotoxic T cells play a role in graft rejection.

Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies

Description : Type I ADR reactions is___________ a) Caused when T-cells bind to a specific antigen b) Caused by tissue injury c) IgE mediated d) Caused by cytotoxic antibodies

Last Answer : c) IgE mediated 

The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the humoral immune response is/are correct? a. Helper T lymphocytes stimulate B lymphocytes through secretion of cytokines such as interleukin 4 and 6 b. A number of cells can aid in presenting the antigen to the helper T cell including B lymphocytes and macrophages c. All antigens require coordinated efforts of the various cellular components of the immune system d. An antigen must be a living microorganism

Description : The initiation of a humoral immune response involves a complex interaction of the antigen, cells and intercellular messengers. Which of the following statement(s) concerning the initiation of the ... various cellular components of the immune system d. An antigen must be a living microorganism

Last Answer : Answer: a, b Stimulation of the immune system occurs after a variety of antigen-presenting cells (B lymphocytes, macrophages, dendritic cells, and Langerhans cells) act to engulf ... polysaccharides), most antigens require coordinated efforts of the various cellular components of the immune system

The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. Treatment with azidothymidine (AZD) appears to prolong survival when administered early in the disease c. Predisposition to infection in HIV infection is primarily due to reduction in the number of helper T cells d. Common infections in patients with AIDS are Pneumocystis, carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Description : The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. ... , carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Last Answer : Answer: b, c, d Acquired immunodeficiency syndrome (AIDS) is a syndrome caused by the human retrovirus (HIV-1) that infects T lymphocytes and causes severe immunosuppression. Individuals who ... to prolong survival when administered early in the course of disease and is considered routine therapy

Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells

Description : Predominant cell types in typical chronic inflammation are all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. NK cells

Last Answer : Polymorphonuclear leukocytes

At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) When HIV damages large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

Description : At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) ... large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

Last Answer : (c) When HIV damages large number of helper T  - lymphocytes

The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages

Description : The AIDS viruses specifically attack which kind of cell? a) B cells b) helper T cells c) killer T cells d) macrophages

Last Answer : ANSWER: B -- HELPER T CELLS

6 The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : 6 The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

All the following statements about fibronectin are true except (A) It is glycoprotein (B) It is a triple helix (C) It is present in extra cellular matrix (D) It binds with integrin receptors of cell

Description : All the following statements about fibronectin are true except (A) It is glycoprotein (B) It is a triple helix (C) It is present in extra cellular matrix (D) It binds with integrin receptors of cell

Last Answer : Answer : A

Which of the following statement(s) is/are true concerning water movement across cell membranes? a. Water moves only actively through cell membrane transport proteins b. For most cells of the body, the transmembrane hydrostatic pressure is 0 c. Water distribution is determined entirely by solute distribution d. Specialized cells such as the glomerulus of the kidney actively transport water to maintain hydrostatic pressure

Description : Which of the following statement(s) is/are true concerning water movement across cell membranes? a. Water moves only actively through cell membrane transport proteins b. For most cells of ... cells such as the glomerulus of the kidney actively transport water to maintain hydrostatic pressure

Last Answer : Answer: b, c The energetics of water transport across cell membranes is simplified by the fact that water moves only passively due to gradients of hydrostatic pressure or water ... water is distributed at equilibrium. Water distribution is determined entirely by solute to solute distribution

In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell proliferation? For example, many cancer cells carry two mutant copies of the gene that codes for a tumor suppressor protein named p53. What is the normal function of p53 that is lost when it is mutated?

Description : In many types of cancer, proteins that are crucial regulators of the cell cycle are often mutated and cannot function correctly. This leads to the evasion of apoptosis and to the loss of control of cell ... protein named p53. What is the normal function of p53 that is lost when it is mutated?

Last Answer : Normally, p53 senses DNA damage and acts as a transcription factor for checkpoint control genes.

RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene

Description : RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene

Last Answer : Answer : A

P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these

Description : P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these

Last Answer : Answer : C

Suppressor tRNAs can neutralize the effects of mutations in (A) Structural genes (B) Promoter regions (C) Enhancer elements(D) All of these

Description : Suppressor tRNAs can neutralize the effects of mutations in (A) Structural genes (B) Promoter regions (C) Enhancer elements(D) All of these

Last Answer : Answer : A

Suppressor mutations occur in (A) Structural genes (B) Promoter regions (C) Silencer elements (D) Anticodons of tRNA

Description : Suppressor mutations occur in (A) Structural genes (B) Promoter regions (C) Silencer elements (D) Anticodons of tRNA

Last Answer : Answer : D

A synthetic nucleotide analogue, used in organ transplantation as a suppressor of immunologic rejection of grafts is (A) Theophylline (B) Cytarabine (C) 4-Hydroxypyrazolopyrimidine (D) 6-Mercaptopurine

Description : A synthetic nucleotide analogue, used in organ transplantation as a suppressor of immunologic rejection of grafts is (A) Theophylline (B) Cytarabine (C) 4-Hydroxypyrazolopyrimidine (D) 6-Mercaptopurine

Last Answer : Answer : D

Which one of the following applies to the disease systemic lupus erythematosus (SLE)? a. It is a type of cytotoxic hypersensitivity. b. It is often accompanied by a butterfly rash. c. It is due to an overreaction of T lymphocytes. d. It is the result of a cellular hypersensitivity.

Description : Which one of the following applies to the disease systemic lupus erythematosus (SLE)? a. It is a type of cytotoxic hypersensitivity. b. It is often accompanied by a butterfly rash. c. It is due to an overreaction of T lymphocytes. d. It is the result of a cellular hypersensitivity.

Last Answer : d. It is the result of a cellular hypersensitivity.

What is the function of the helper T cell?

Description : What is the function of the helper T cell? 

Last Answer : The helper T cells assist the immune process by helping other cells in the immune system to achieve an efficient immune response. In antibody- mediated immunity, the helper T cell helps recognize ... cytotoxic T cells. These cells are critical to both antibody mediated and cell- mediated immunity. 

Predominant cell types in typical chronic inflammatory reactions include all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. None of these

Description : Predominant cell types in typical chronic inflammatory reactions include all of the following EXCEPT: A A. Polymorphonuclear leukocytes B. Macrophages C. T helper lymphocytes D. None of these

Last Answer : Polymorphonuclear leukocytes

Which one of the following statements is correct with respect to AIDS? (a) The HIV can be transmitted through eating food together with an infected person. (b) Drug addicts are least susceptible to HIV infection.(c) AIDS patients are being fully cured cent per cent with proper care and nutrition. (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

Description : Which one of the following statements is correct with respect to AIDS? (a) The HIV can be transmitted through eating food together with an infected person. (b) Drug addicts are least ... and nutrition. (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

Last Answer : (d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.

HIV that causes AIDS, first starts destroying (a) helper T-lymphocytes (b) thrombocytes (c) B-lymphocytes (d) leucocytes.

Description : HIV that causes AIDS, first starts destroying (a) helper T-lymphocytes (b) thrombocytes (c) B-lymphocytes (d) leucocytes.

Last Answer : (a) helper T-lymphocytes

To activate a bound helper T lymphocyte, the macrophage produces a. Interleukin-1 (IL-1) b. granzymes c. Interferon

Description : To activate a bound helper T lymphocyte, the macrophage produces a. Interleukin-1 (IL-1) b. granzymes c. Interferon

Last Answer : a. Interleukin-1 (IL-1)

The _____ cell contains on its surface a CD4 receptor site that enhances binding to the macrophage. a. Helper T b. molecular patterns (PAMPs) c. plasma d. B

Description : The _____ cell contains on its surface a CD4 receptor site that enhances binding to the macrophage. a. Helper T b. molecular patterns (PAMPs) c. plasma d. B

Last Answer : a. IgG

With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above

Description : With regard to HLA class 1 antigen: a. they are expressed on all nucleated cells b. they are essential for viral antigen recognition by cytotoxic cells c. the genes for HLA class 1 molecules are located on chromosome 6 and 15 d. all above

Last Answer : all above

The following does not apply to cancer chemotherapy: A. Each treatment with a cytotoxic drug kills a constant number of malignant cells B. Drugs are generally used at maximum tolerated doses C. The same regimen which is palliative for a large solid tumour may be curative after surgical removal of the tumour D. Combination regimens using several drugs in succession are superior to single drug used continuously

Description : The following does not apply to cancer chemotherapy: A. Each treatment with a cytotoxic drug kills a constant number of malignant cells B. Drugs are generally used at maximum tolerated ... D. Combination regimens using several drugs in succession are superior to single drug used continuously

Last Answer : A. Each treatment with a cytotoxic drug kills a constant number of malignant cells

Amanitin the mushroom poison inhibits (A) Glycoprotein synthesis (B) ATP synthesis (C) DNA synthesis (D) mRNA synthesis

Description : Amanitin the mushroom poison inhibits (A) Glycoprotein synthesis (B) ATP synthesis (C) DNA synthesis (D) mRNA synthesis

Last Answer : Answer : D

TSH hormone biochemically is a (A) Protein (B) Fat (C) Glycoprotein (D) Carbohydrate 232 MCQs IN BIOCHEMISTRY

Description : TSH hormone biochemically is a (A) Protein (B) Fat (C) Glycoprotein (D) Carbohydrate 232 MCQs IN BIOCHEMISTRY

Last Answer : Answer : C

All the following statements about TSH are true except (A) It is a glycoprotein (B) It is made up of α- and β-subunits (C) Receptor recognition involves both the subunits (D) Its subunit is identical with those of FSH and LH

Description : All the following statements about TSH are true except (A) It is a glycoprotein (B) It is made up of α- and β-subunits (C) Receptor recognition involves both the subunits (D) Its subunit is identical with those of FSH and LH

Last Answer : Answer : D