Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures

Choose the correct statement about lamotrigine:
A. It is a dopaminergic agonist used in
parkinsonism
B. It acts by blocking NMDA-type of glutamate
receptors
C. It is a broad spectrum antiepileptic drug
D. It suppresses tonic-clonic seizures, but
worsens absence seizures
by

1 Answer

Answer :

C. It is a broad spectrum antiepileptic drug
by

Related questions

he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide

Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide

Last Answer : C. Sodium valproate

The following is true of topiramate except: A. It is a broad spectrum antiepileptic drug B. It inhibits the enzyme carbonic anhydrase C. It is used as add-on therapy in refractory partial seizures D. It is not effective in generalized tonic-clonic seizures

Description : The following is true of topiramate except: A. It is a broad spectrum antiepileptic drug B. It inhibits the enzyme carbonic anhydrase C. It is used as add-on therapy in refractory partial seizures D. It is not effective in generalized tonic-clonic seizures

Last Answer : D. It is not effective in generalized tonic-clonic seizures

Select the drug having a narrow spectrum antiepileptic activity restricted to absence seizures: A. Lamotrigine B. Ethosuccimide C. Sodium valproate D. Primidone

Description : Select the drug having a narrow spectrum antiepileptic activity restricted to absence seizures: A. Lamotrigine B. Ethosuccimide C. Sodium valproate D. Primidone

Last Answer : . Ethosuccimide

Which of the following is the most suitable drug for a 6-year-old girl suffering from absence seizures with occasional generalized tonic-clonic seizures: A. Ethosuccimide B. Sodium valproate C. Carbamazepine D. Phenytoin

Description : Which of the following is the most suitable drug for a 6-year-old girl suffering from absence seizures with occasional generalized tonic-clonic seizures: A. Ethosuccimide B. Sodium valproate C. Carbamazepine D. Phenytoin

Last Answer : B. Sodium valproate

Select the antiepileptic drug that in addition is a preferred treatment for post herpetic neuralgia and pain due to diabetic neuropathy: A. Carbamazepine B. Gabapentin C. Lamotrigine D. Primidone

Description : Select the antiepileptic drug that in addition is a preferred treatment for post herpetic neuralgia and pain due to diabetic neuropathy: A. Carbamazepine B. Gabapentin C. Lamotrigine D. Primidone

Last Answer : B. Gabapentin

Strychnine produces convulsions by: A. Stimulating NMDA receptors B. Facilitating the excitatory transmitter glutamate C. Blocking the inhibitory transmitter GABA D. Blocking the inhibitory transmitter glycine

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Last Answer : D. Blocking the inhibitory transmitter glycine

Select the factor which indicates that withdrawal of the successfully used antiepileptic medication is likely to result in recurrence of seizures: A. Childhood epilepsy B. Partial seizures C. Treatment started soon after seizure onset D. Absence of EEG abnormality

Description : Select the factor which indicates that withdrawal of the successfully used antiepileptic medication is likely to result in recurrence of seizures: A. Childhood epilepsy B. Partial seizures C. Treatment started soon after seizure onset D. Absence of EEG abnormality

Last Answer : B. Partial seizures

The following antiepileptic drug raises pentylene tetrazol seizure threshold but does not modify maximal electroshock seizures: A. Ethosuximide B. Carbamazepine C. Primidone D. Phenobarbitone

Description : The following antiepileptic drug raises pentylene tetrazol seizure threshold but does not modify maximal electroshock seizures: A. Ethosuximide B. Carbamazepine C. Primidone D. Phenobarbitone

Last Answer : A. Ethosuximide

Diazepam is indicated in the following conditions except: A. Generalized tonic-clonic (grand mal) epilepsy B. Tetanus C. Febrile convulsions D. Cardiac catheterization

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Last Answer : A. Generalized tonic-clonic (grand mal) epilepsy

Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. Used alone, its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

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Last Answer : C. Used alone, its effective doses produce intolerable side effect

Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

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Last Answer : D. All of the above

Choose the correct statement about the use of propranolol in anxiety: A. Being nonsedative, it is the drug of choice in chronic anxiety states B. It suppresses the psychological component of anxiety C. It suppresses the autonomic manifestations of acutely stressful situations D. Both ‘B’ and ‘C’ are correct

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Last Answer : C. It suppresses the autonomic manifestations of acutely stressful situations

Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem

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Last Answer : B. Amiodarone

Choose the correct statement about topotecan: A. It is a DNA topoisomerase I inhibitor which causes single strand DNA breaks B. It is a cell cycle specific anticancer drug C. It is a COMT-inhibitor used in advanced parkinsonism D. Both 'A' and 'B' are correc

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Last Answer : D. Both 'A' and 'B' are correct

The following category of drugs is not indicated in early/mild cases of Parkinson's disease: A. Central anticholinergic B. MAO-B inhibitor C. COMT inhibitor D. Nonergoline dopaminergic agonist

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Last Answer : C. COMT inhibitor

A combination of two or more antiepileptic drugs is used: A. Routinely in all types of epilepsy B. In all cases of complex partial seizures C. In all cases of secondarily generalized seizures D. Only when monotherapy with first/second choice drugs fails

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Last Answer : D. Only when monotherapy with first/second choice drugs fails

Which general anaesthetic selectively inhibits excitatory NMDA receptors: A. Thiopentone B. Halothane C. Desflurane D. Ketamine

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Last Answer : D. Ketamine

Choose the correct statement about tetracyclines: A. Being broad spectrum antibioics they are dependable for empirical treatment of lifethreatening infections B. Currently, they are not the first choice antibiotic for any specific infection C. They reduce stool volume and duration of diarrhoea in cholera D. The are preferred for treatment of anaerobic bacterial infections

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Finasteride acts by: A. Blocking testosterone receptors in the prostate gland B. Reducing testosterone secretion from testes C. Reducing LH secretion from pituitary D. Lowering circulating as well as prostatic dihydrotestosterone concentration

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Activation of the following type of receptors present on myenteric neurones by metoclopramide is primarily responsible for enhanced acetylcholine release improving gastric motility: A. Muscarinic M1 B. Serotonergic 5-HT3 C. Serotonergic 5-HT4 D. Dopaminergic D2

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Last Answer : C. Serotonergic 5-HT4

Ropinirole differs from bromocriptine in the following respect: A. It does not directly activate dopamine D2 receptors B. It produces milder gastrointestinal side effects C. In early cases of parkinsonism, it is less likely to need levodopa supplementation D. Both 'B' and 'C' are correct

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Last Answer : D. Both 'B' and 'C' are correct

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

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A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

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A 92-year-old woman is an inpatient in the geriatric unit. She has multivascular dementia. She is more confused and agitated. She has been given lorazepam 4 mg intramuscularly. She is now unconscious with a generalized tonic clonic seizure and a respiratory rate of 6 breaths per minute. Which of the following could be used to reverse the effects of the lorazepam? A. Activated charcoal B. Flumazenil C. N-acetyl cysteine D. Naloxone E. Protamine sulphate

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Last Answer : B. Flumazenil 

Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route

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Last Answer : B. It suppresses postoperative nausea and vomitin

Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin therapy prevents granulomatous lesions and cardiac complications of acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer

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Last Answer : B. Aspirin suppresses flushing attending large dose of nicotinic acid

In the treatment of parkinsonism, bromocriptine differs from levodopa in the following respects except: A. It does not need conversion to an active metabolite B. It has a longer duration of action C. It activates dopamine D2 receptors, with little/antagonistic action on D1 receptors D. It does not produce behavioral/psychiatric side effect

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Last Answer : D. It does not produce behavioral/psychiatric side effects

The following is/are true of mesalazine: A. It exerts mainly local antiinflammatory action in the lower gut B. It is a broad spectrum antidiarrhoeal drug C. It can be administered as a retention enema D. Both 'A' and 'C

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The following drug reduces the effect of oral anticoagulants: A. Broad spectrum antibiotic B. Cimetidine C. Aspirin D. Oral contraceptive

Description : The following drug reduces the effect of oral anticoagulants: A. Broad spectrum antibiotic B. Cimetidine C. Aspirin D. Oral contraceptive

Last Answer : D. Oral contraceptive

The following is a tetracyclic antidepressant that has additional dopamine blocking and neuroleptic properties, as well as greater propensity to cause seizures in overdose: A. Amoxapine B. Doxepin C. Dothiepin D. Trazodone

Description : The following is a tetracyclic antidepressant that has additional dopamine blocking and neuroleptic properties, as well as greater propensity to cause seizures in overdose: A. Amoxapine B. Doxepin C. Dothiepin D. Trazodone

Last Answer : A. Amoxapine

Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

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Last Answer : C. Tyrosine protein kinase receptors

Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers blood glucose in both type 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes

Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes

Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus

Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Description : Select the drug that suppresses essential tremor, but not parkinsonian tremor: A. Procyclidine B. Propranolol C. Promethazine D. Prochlorperazine

Last Answer : B. Propranolol

The following is true about entacapone except: A. It acts by inhibiting degradation of dopamine in the brain B. If prolongs the therapeutic effect of levodopacarbidopa in parkinsonism C. It can accentuate levodopa induced dyskinesias D. It can cause diarrhoea as a side effec

Description : The following is true about entacapone except: A. It acts by inhibiting degradation of dopamine in the brain B. If prolongs the therapeutic effect of levodopacarbidopa in parkinsonism C. It can accentuate levodopa induced dyskinesias D. It can cause diarrhoea as a side effec

Last Answer : A. It acts by inhibiting degradation of dopamine in the brain

Choose the correct statement about trimetazidine: A. It is a novel calcium channel blocker B. It improves tissue perfusion by modifying rheological property of blood C. It is an antianginal drug which acts by nonhaemodynamic mechanisms D. Both 'A' and 'B' are correct

Description : Choose the correct statement about trimetazidine: A. It is a novel calcium channel blocker B. It improves tissue perfusion by modifying rheological property of blood C. It is an antianginal drug which acts by nonhaemodynamic mechanisms D. Both 'A' and 'B' are correct

Last Answer : C. It is an antianginal drug which acts by nonhaemodynamic mechanisms

The following statement is not true of sulbactam: A. It is a broad spectrum β-lactamase inhibitor B. It does not augment the activity of ampicillin against bacteria that are sensitive to the latter C. It induces chromosomal β-lactamases D. Combined with ampicillin, it is highly effective against penicillinase producing N. gonorrhoeae

Description : The following statement is not true of sulbactam: A. It is a broad spectrum β-lactamase inhibitor B. It does not augment the activity of ampicillin against bacteria that are sensitive ... β-lactamases D. Combined with ampicillin, it is highly effective against penicillinase producing N. gonorrhoeae

Last Answer : C. It induces chromosomal β-lactamases

The drug which abolishes the therapeutic effect of levodopa in parkinsonism, but not that of levodopacarbidopa combination is: A. Metoclopramide B. Pyridoxine C. Chlorpromazine D. Isoniazid

Description : The drug which abolishes the therapeutic effect of levodopa in parkinsonism, but not that of levodopacarbidopa combination is: A. Metoclopramide B. Pyridoxine C. Chlorpromazine D. Isoniazid

Last Answer : B. Pyridoxine

Pyritinol (pyrithioxine) is used as: A. Analeptic drug B. Cognition enhancing drug C. Antiepileptic drug

Description : Pyritinol (pyrithioxine) is used as: A. Analeptic drug B. Cognition enhancing drug C. Antiepileptic drug

Last Answer : B. Cognition enhancing dru

The following antiepileptic drug is likely to cause hyponatremia as a side effect, especially in elderly patients: A. Primidone B. Carbamazepine C. Phenytoin D. Sodium valproate

Description : The following antiepileptic drug is likely to cause hyponatremia as a side effect, especially in elderly patients: A. Primidone B. Carbamazepine C. Phenytoin D. Sodium valproate

Last Answer : B. Carbamazepine

Select the antiepileptic drug that is effective in manicdepressive illness as well: A. Ethosuccimide B. Primidone C. Phenobarbitone D. Carbamazepine

Description : Select the antiepileptic drug that is effective in manicdepressive illness as well: A. Ethosuccimide B. Primidone C. Phenobarbitone D. Carbamazepine

Last Answer : D. Carbamazepine

The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide

Description : The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide

Last Answer : B. Phenobarbitone

Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes little myocardial depression and hypotension C. It has broad spectrum antiarrhythmic efficacy in atrial as well as ventricular arrhythmias D. Both ‘A’ and ‘B’ are correct

Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Which antileprotic drug suppresses lepra reaction and reversal reaction as well: A. Dapsone B. Rifampin C. Clofazimine D. Minocycline

Description : Which antileprotic drug suppresses lepra reaction and reversal reaction as well: A. Dapsone B. Rifampin C. Clofazimine D. Minocycline

Last Answer : C. Clofazimine

The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug

Description : The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in ... locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug

Last Answer : B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally

Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Last Answer : A. They do not cross the blood-brain barrier

Ergotamine relieves migraine by: A. Blocking vascular α adrenergic receptors B. Blocking vascular 5-HT2 receptors C. Dilating cranial arterio-venous shunt channels D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

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Last Answer : D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality C. They compromise quality of life more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

Description : Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They ... more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality

Choose the correct statement(s) about dofetilide: A. It is a pure class III antiarrhythmic B. It has no adrenergic/cholinergic receptor blocking property C. It selectively depresses the rapid component of delayed rectifier K+ current in myocardial fibres D. All of the above

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Last Answer : D. All of the above

The extrapyramidal adverse effect of antipsychotic drug therapy which does not respond to central anticholinergics is: A. Parkinsonism B. Acute muscle dystonia C. Rabbit syndrome D. Tardive dyskinesia

Description : The extrapyramidal adverse effect of antipsychotic drug therapy which does not respond to central anticholinergics is: A. Parkinsonism B. Acute muscle dystonia C. Rabbit syndrome D. Tardive dyskinesia

Last Answer : D. Tardive dyskinesia

For majority of patients of parkinsonism the standard drug therapy is: A. Levodopa B. Levodopa + carbidopa C. Levodopa + trihexiphenidyl D. Bromocriptine

Description : For majority of patients of parkinsonism the standard drug therapy is: A. Levodopa B. Levodopa + carbidopa C. Levodopa + trihexiphenidyl D. Bromocriptine

Last Answer : B. Levodopa + carbidopa