What are the inhibitors of phosphofructokinase?

What are the inhibitors of phosphofructokinase? 
by

1 Answer

Answer :

ATP, Citrate, Glucocorticoids. 
by

Related questions

Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase

Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase

Last Answer : Answer : B

Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Last Answer : Answer : D

A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase

Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase

Last Answer : Answer : C

ATP is a co-substrate as well as an allosteric inhibitor of (A) Phosphofructokinase (B) Hexokinase (C) Glucokinase (D) None of these

Description : ATP is a co-substrate as well as an allosteric inhibitor of (A) Phosphofructokinase (B) Hexokinase (C) Glucokinase (D) None of these

Last Answer : Answer : A

Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate

Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate

Last Answer : Answer : D

Which of the following is an allosteric enzyme? (A) Phosphohexose isomerase (B) Phosphotriose isomerase (C) Lactate dehydrogenase (D) Phosphofructokinase

Description : Which of the following is an allosteric enzyme? (A) Phosphohexose isomerase (B) Phosphotriose isomerase (C) Lactate dehydrogenase (D) Phosphofructokinase

Last Answer : Answer : D

Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase

Description : Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase

Last Answer : Answer : C

Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase

Description : Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase

Last Answer : Answer : A

Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase

Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase

Last Answer : Answer : B

One of the enzymes regulating glycolysis is (A) Phosphofructokinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Phosphotriose isomerase (D) Phosphohexose isomerase

Description : One of the enzymes regulating glycolysis is (A) Phosphofructokinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Phosphotriose isomerase (D) Phosphohexose isomerase

Last Answer : Answer : A

Phosphofructokinase key enzyme in glycolysis is inhibited by (A) Citrate and ATP (B) AMP (C) ADP (D) TMP

Description : Phosphofructokinase key enzyme in glycolysis is inhibited by (A) Citrate and ATP (B) AMP (C) ADP (D) TMP

Last Answer : Answer : A

In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Last Answer : Answer : B

Pasteur effect is (A) Inhibition of glycolysis (B) Oxygen is involved (C) Inhibition of enzyme phosphofructokinase (D) All of these

Description : Pasteur effect is (A) Inhibition of glycolysis (B) Oxygen is involved (C) Inhibition of enzyme phosphofructokinase (D) All of these

Last Answer : D

The reaction catalysed by phosphofructokinase (A) Is activated by high concentrations of ATP and citrate (B) Uses fruitose-1-phosphate as substrate (C) Is the rate-limiting reaction of the glycolytic pathway (D) Is inhibited by fructose 2, 6-bisphosphate

Description : The reaction catalysed by phosphofructokinase (A) Is activated by high concentrations of ATP and citrate (B) Uses fruitose-1-phosphate as substrate (C) Is the rate-limiting reaction of the glycolytic pathway (D) Is inhibited by fructose 2, 6-bisphosphate

Last Answer : C

The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these

Description : The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these

Last Answer : D

The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)

Description : The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)

Last Answer : D

McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

Description : McArdle’s disease is due to the deficiency of (A) Glucose-6-phosphatase (B) Phosphofructokinase (C) Liver phosphorylase (D) muscle phosphorylase

Last Answer : D

Fructose-2, 6-biphosphate is formed by the action of (A) Phosphofructokinase-1 (B) Phosphofructokinase-2 (C) Fructose biphosphate isomerase (D) Fructose-1, 6-biphosphatase

Description : Fructose-2, 6-biphosphate is formed by the action of (A) Phosphofructokinase-1 (B) Phosphofructokinase-2 (C) Fructose biphosphate isomerase (D) Fructose-1, 6-biphosphatase

Last Answer : B

Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors

Description : Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors

Last Answer : Answer : C

Vmax of an enzyme may be affected by (A) pH (B) Temperature (C) Non-competitive inhibitors (D) All of these

Description : Vmax of an enzyme may be affected by (A) pH (B) Temperature (C) Non-competitive inhibitors (D) All of these

Last Answer : Answer : D

Competitive inhibitors (A) Decrease the Km (B) Decrease the Vmax (C) Increase the Km (D) Increase the Vmax

Description : Competitive inhibitors (A) Decrease the Km (B) Decrease the Vmax (C) Increase the Km (D) Increase the Vmax

Last Answer : Answer : C

Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalysed by (a) phosphofructokinase (b) aldolase (c) hexokinase (d) enolase.

Description : Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalysed by (a) phosphofructokinase (b) aldolase (c) hexokinase (d) enolase.

Last Answer : (c) hexokinase

What are some of the best or strongest DHT blockers/inhibitors?

Description : What are some of the best or strongest DHT blockers/inhibitors?

Last Answer : partyrock, you might want to explain what DHT blockers do. I had no idea and had to look up what this meant. I have no experience with them.

Difference between competitive inhibitors and non-competitive inhibitors? -Biology

Description : Difference between competitive inhibitors and non-competitive inhibitors? -Biology

Last Answer : answer:

What are irreversible inhibitors? -Biology

Description : What are irreversible inhibitors? -Biology

Last Answer : answer:

What are enzyme inhibitors? -Biology

Description : What are enzyme inhibitors? -Biology

Last Answer : answer:

Clinical significance of competitive inhibitors -Biology

Description : Clinical significance of competitive inhibitors -Biology

Last Answer : answer:

Names of seed germination inhibitors. -Biology

Description : Names of seed germination inhibitors. -Biology

Last Answer : answer:

Names of seed germination inhibitors. -Biology

Description : Names of seed germination inhibitors. -Biology

Last Answer : answer:

How do proton pump inhibitors work ?

Description : How do proton pump inhibitors work ?

Last Answer : Proton pump inhibit is a group of drugs whose main function is to reduce chronic acid production in the stomach. Although there are different medications in this group , there is no evidence ... stomach by ingesting food protects us from gastric and ulcer diseases by affecting the enzyme system.

$ Enzymes are special types of proteins. ! Those substances which interfere with the action of enzymes are called inhibitors.

Description : $ Enzymes are special types of proteins. ! Those substances which interfere with the action of enzymes are called inhibitors.

Last Answer : $ Enzymes are special types of proteins. ! Those substances which interfere with the action of enzymes are ... wrong D. If both As and R are wrong.

Do non competitive inhibitors bind to the active site?

Description : Do non competitive inhibitors bind to the active site?

Last Answer : Feel Free to Answer

Example of growth inhibitors

Description : Example of growth inhibitors

Last Answer : Ans. Abscisic acid and Ethylene

Lowland applied nitrification inhibitors

Description : Lowland applied nitrification inhibitors

Last Answer : Ans. Oxamide (31%N) and Thiourea (36.8%N)

Which of the following statements about hypertension in diabetes patients is/are correct? A. Hypertension worsens the macrovascular disease of diabetes patients. B. Hypertension accelerates the progression of diabetic nephropathy. C. Hypertension is associated with sodium retention in diabetes patients. D. Angiotensin-converting enzyme (ACE) inhibitors should be used in all patients with chronic hyperglycemia, regardless of the presence of hypertension. E. Diuretics, as single-drug therapy, are not indicated in the treatment of hypertension in diabetes patients.

Description : Which of the following statements about hypertension in diabetes patients is/are correct? A. Hypertension worsens the macrovascular disease of diabetes patients. B. Hypertension accelerates the ... single-drug therapy, are not indicated in the treatment of hypertension in diabetes patients.

Last Answer : Answer: ABCDE DISCUSSION: All of the answers listed are correct. By damaging endothelial cells, hypertension worsens macrovascular disease in all patients but especially in diabetics. Hypertension ... is not indicated because the chronic state of dehydration in such patients may become worse

Tyramine induces release of noradrenaline from adrenergic nerve endings (a) By depolarizing the axonal membrane (b) By mobilizing Ca2+ (c) By a nonexocytotic process (d) Only in the presence of MAO inhibitors

Description : Tyramine induces release of noradrenaline from adrenergic nerve endings (a) By depolarizing the axonal membrane (b) By mobilizing Ca2+ (c) By a nonexocytotic process (d) Only in the presence of MAO inhibitors

Last Answer : Ans: C

Postural hypotension is a common adverse effect of which one of the following types of drugs ? (a) ACE inhibitors (b) Alpha-receptor blockers (c) Arteriolar dilators (d) ß1 – selective receptor blockers (e) Nonselective ß - blockers

Description : Postural hypotension is a common adverse effect of which one of the following types of drugs ? (a) ACE inhibitors (b) Alpha-receptor blockers (c) Arteriolar dilators (d) ß1 – selective receptor blockers (e) Nonselective ß - blockers

Last Answer : Ans: B

Cylcoocygenase-II specific inhibitors block the following (a) Production of cytoprotective prostaglandins (b) Tumor necrosis factor - a (c) Production of prostaglandins responsible for pain and inflammation

Description : Cylcoocygenase-II specific inhibitors block the following (a) Production of cytoprotective prostaglandins (b) Tumor necrosis factor - a (c) Production of prostaglandins responsible for pain and inflammation

Last Answer : Ans: C

Scarification of seeds is done for removing (a) Dormancy (b) Germination inhibitors (c) Growth (d) Embryo

Description : Scarification of seeds is done for removing (a) Dormancy (b) Germination inhibitors (c) Growth (d) Embryo

Last Answer : Ans:(a)

Which plant hormones are known as growth inhibitors?

Description : Which plant hormones are known as  growth inhibitors?

Last Answer : Abscisic acid and Ethylene

RNA polymerase inhibitors - Why is this so?

Description : The bacterial RNA polymerase inhibitors rifampicin and streptolydigin each bind to the same subunitof the enzyme, but their overall effect on the activity of the enzyme is different. Why is this so?

Last Answer : Each of these inhibitors binds exclusively to the β-subunit of RNA polymerase. This subunit is involved in both initiation and elongation of RNA chain growth. Rifampicin binds to the subunit in such ... on elongation. Streptolydigin, on the other hand, binds in a manner that blocks both activities. 

Urine volume is increased with: a. carbonic anhydrase inhibitors b. hyperglycaemia c. increased aldosterone secretion d. damage to the posterior pituitary

Description : Urine volume is increased with: a. carbonic anhydrase inhibitors b. hyperglycaemia c. increased aldosterone secretion d. damage to the posterior pituitary

Last Answer : damage to the posterior pituitary

At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers

Description : At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers

Last Answer : increased by cocaine which inhibit reuptake of adrenaline

Low temperature helps to _________ growth inhibitors: a. Increase b. Decrease c. Store d. Produce

Description : Low temperature helps to _________ growth inhibitors: a. Increase b. Decrease c. Store d. Produce

Last Answer : Decrease

Insecticides are specific inhibitors of— (A) Excretory system (B) Digestive system (C) Nervous system (D) Blood Circulatory system

Description : Insecticides are specific inhibitors of— (A) Excretory system (B) Digestive system (C) Nervous system (D) Blood Circulatory system

Last Answer : (D) Blood Circulatory system

‘Pusa Neem’ (Neem-oil coated urea)— product used as inhibitors for slow release, was designated and reported by—(A) Dr. Rajendra Prasad and Colleagues (B) Dr. R.S. Paroda (C) Dr. G.B. Singh (D) Dr. M.S. Randhawa

Description : ‘Pusa Neem’ (Neem-oil coated urea)— product used as inhibitors for slow release, was designated and reported by—(A) Dr. Rajendra Prasad and Colleagues (B) Dr. R.S. Paroda (C) Dr. G.B. Singh (D) Dr. M.S. Randhawa

Last Answer : (A) Dr. Rajendra Prasad and Colleagues

Many _________ in super optimal concentrations also act as growth inhibitors : a. Auxins b. Gibberellins c. Cytokinins d. All of above

Description : Many _________ in super optimal concentrations also act as growth inhibitors : a. Auxins b. Gibberellins c. Cytokinins d. All of above

Last Answer : Auxins

Which one of the following statements regarding enzyme inhibition is correct? (a) Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein. (b) Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme. (c) Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate. (d) Non-competitive inhibitors often bind to the enzyme irreversibly.

Description : Which one of the following statements regarding enzyme inhibition is correct? (a) Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein. (b ... large amount of substrate. (d) Non-competitive inhibitors often bind to the enzyme irreversibly.

Last Answer : (b) Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme

Which of the following medications represents the category proton (gastric acid) pump inhibitors? a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine-triphosphatase pump on the surface of the parietal cells. b) Sucralfate (Carafate) Sucralfate is a cytoprotective drug. c) Famotidine (Pepcid) Famotidine is a histamine-2 receptor antagonist. d) Metronidazole (Flagyl) Metronidazole is an antibiotic, specifically an amebicide.

Description : Which of the following medications represents the category proton (gastric acid) pump inhibitors? a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine ... antagonist. d) Metronidazole (Flagyl) Metronidazole is an antibiotic, specifically an amebicide.

Last Answer : a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine-triphosphatase pump on the surface of the parietal cells.

Of the following categories of medications, which is used in combination with bismuth salts to eradicate Helicobacter pylori? a) Antibiotics Antibiotics and bismuth salts are given to eradicate H. pylori. b) Antacids Antacids are given to manage gastric acidity. c) Proton pump inhibitors Proton pump inhibitors are given to decrease acid secretion. d) Histamine-2 receptor antagonists Histamine-2 receptor antagonists are given to decrease the acid secretion in the stomach.

Description : Of the following categories of medications, which is used in combination with bismuth salts to eradicate Helicobacter pylori? a) Antibiotics Antibiotics and bismuth salts are given to eradicate ... antagonists Histamine-2 receptor antagonists are given to decrease the acid secretion in the stomach.

Last Answer : a) Antibiotics Antibiotics and bismuth salts are given to eradicate H. pylori.