Description : The bacterial RNA polymerase inhibitors rifampicin and streptolydigin each bind to the same subunitof the enzyme, but their overall effect on the activity of the enzyme is different. Why is this so?
Last Answer : Each of these inhibitors binds exclusively to the β-subunit of RNA polymerase. This subunit is involved in both initiation and elongation of RNA chain growth. Rifampicin binds to the subunit in such ... on elongation. Streptolydigin, on the other hand, binds in a manner that blocks both activities.