Which is the anticoagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin

Which is the anticoagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin
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(2) Heparin Explanation: Heparin, a highly sulfated glycosaminoglycan, is widely used as an inject able anticoagulant, and has the highest negative charge density of any known biological molecule. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines. Although it is used principally in medicine for anticoagulation, its true physiological role in the body remains unclear, because blood anti-coagulation is achieved mostly by heparin sulfate proteoglyeans derived from endothelial cells.
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Which is the anti-coagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin

Description : Which is the anti-coagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin

Last Answer : Heparin

Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning coagulation tests? a. Prothrombin time (PT) measures both the intrinsic and extrinsic clotting pathways and fibrinogen b. Activated partial thromboplastin time (aPTT) can be used to monitor both oral anticoagulation with Warfarin and intravenous anticoagulation with heparin c. Thrombin clotting time (TCT) is a measurement of the time it takes for exogenously administered thrombin to turn plasma fibrinogen into fibrin clot d. Whole blood activated clotting time (ACT) is a measurement of the ability of whole blood to clot and is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascu

Description : Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning ... is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascular operations

Last Answer : Answer: a, c, d Coagulation tests include prothrombin time (PT), which measures the intrinsic and extrinsic pathways of fibrinogen production and is the most common method for ... more while for peripheral vascular applications, values of 250 seconds or greater are considered appropriate

Blood does not clot in the blood vessels due to the presence of – (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Description : Blood does not clot in the blood vessels due to the presence of – (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Last Answer : (3) Heparin Explanation: There are two major facets of the clotting mechanism — the platelets, and the thrombin system. The thrombin system consists of several blood proteins that, when bleeding occurs, become activated.

The following are true about blood coagulation: a. heparin inhibits blood coagulation through its interference with vitamin K metabolism in the liver b. addition of vitamin K to freshly drawn blood delays clotting c. thrombin converts fibrinogen to fibrin d. platelets are essential for blood clot

Description : The following are true about blood coagulation: a. heparin inhibits blood coagulation through its interference with vitamin K metabolism in the liver b. addition of vitamin K to freshly drawn ... delays clotting c. thrombin converts fibrinogen to fibrin d. platelets are essential for blood clot

Last Answer : thrombin converts fibrinogen to fibrin

Blood does not clot in the blood vessels due to the presence of (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Description : Blood does not clot in the blood vessels due to the presence of (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Last Answer : Thrombin

Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of prothrombin to thrombin

Description : Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of prothrombin to thrombin

Last Answer : Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of ... . If both Assertion & Reason are false.

As thrombin generation proceeds, the body has natural anticoagulant systems opposing further thrombus formation. Natural anticoagulants include: a. Tissue plasminogen activator (TPA) b. Antithrombin III c. Activated protein C d. Heparin cofactor II

Description : As thrombin generation proceeds, the body has natural anticoagulant systems opposing further thrombus formation. Natural anticoagulants include: a. Tissue plasminogen activator (TPA) b. Antithrombin III c. Activated protein C d. Heparin cofactor II

Last Answer : Answer: b, c, d Just as thrombin generation is the key to coagulation, antithrombin III is the most central anticoagulant proteins. This glycoprotein binds to thrombin, preventing its removal of ... in the body. Therefore, TPA is part of the fibrinolytic system rather than a natural anticoagulant

he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombin C. Activation of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi

Hemostasis and the cessation of bleeding require which of the following processes? A. Adherence of platelets to exposed subendothelial glycoproteins and collagen with subsequent aggregation of platelets and formation of a hemostatic plug. B. Interaction of tissue factor with factor VII circulating in the plasma. C. The production of thrombin via the coagulation cascade with conversion of fibrinogen to fibrin. D. Cross-linking of fibrin by factor XIII.

Description : Hemostasis and the cessation of bleeding require which of the following processes? A. Adherence of platelets to exposed subendothelial glycoproteins and collagen with subsequent aggregation of platelets and ... conversion of fibrinogen to fibrin. D. Cross-linking of fibrin by factor XIII.

Last Answer : Answer: ABCD DISCUSSION: Hemostasis requires the interaction of platelets with the exposed subendothelial structures at the site of injury followed by aggregation of more platelets in that area. ... form a stable clot that incorporates the platelet plug and fibrin thrombus into a stable clot

Vitamin K is required for (a) change of prothrombin into thrombin (b) synthesis of prothrombin (c) change of fibrinogen to fibrin (d) formation of thromboplastin.

Description : Vitamin K is required for (a) change of prothrombin into thrombin (b) synthesis of prothrombin (c) change of fibrinogen to fibrin (d) formation of thromboplastin.

Last Answer : (b) synthesis of prothrombin

During hemdialysis process I. blood drained from a conveniend artery and anticoagulant is added (heparin). II. Removal of nitrogenous waste from blood

Description : During hemdialysis process I. blood drained from a conveniend artery and anticoagulant is added (heparin). II. Removal of nitrogenous waste from blood

Last Answer : During hemdialysis process I. blood drained from a conveniend artery and anticoagulant is added (heparin). II. ... D. `I rarr IV rarr II rarr III`

Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin ?

Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin ?

Last Answer : Which type of white blood cells are concerned with the release of histamine and the natural ... Eosinophils B. Monocytes C. Neutrophils D. Basophils

Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin? (a) Eosinophils (b) Monocytes (c) Neutrophils (d) Basophils

Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin? (a) Eosinophils (b) Monocytes (c) Neutrophils (d) Basophils

Last Answer : d) Basophils

The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation C. Heparin is the physiologically active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro

Description : The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation ... active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro

Last Answer : C. Heparin is the physiologically active circulating anticoagulant

Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous thrombosis include: a. Enhancement of antithrombin III activity b. A decrease in thrombin availability c. Inhibition of platelet aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

Description : Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous ... aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

Last Answer : Answer: a, b, c Low-dose heparin is thought to protect against venous thrombosis through three different mechanisms. First, antithrombin III activity with its inhibition of activated Factor X is ... release reaction. The standard doses of heparin administered (5000 units bid) does not affect aPTT

When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Last Answer : Ans: A

Sickle cell disease is inherited due to defective copies of _________gene. a. Heparin b. Haemoglobin c. Creatinine d. Fibrinogen

Description : Sickle cell disease is inherited due to defective copies of _________gene. a. Heparin b. Haemoglobin c. Creatinine d. Fibrinogen

Last Answer : b. Haemoglobin

When a wound occurs in humans, the platelets in th blood activate a substance which starts the clotting process. The substance which starts the clotting is: a) adenosine (pron: ah-den-ah-seen) b) histamine c) lecithin (pron: less-ah-thin) d) thrombin

Description : When a wound occurs in humans, the platelets in th blood activate a substance which starts the clotting process. The substance which starts the clotting is: a) adenosine (pron: ah-den-ah-seen) b) histamine c) lecithin (pron: less-ah-thin) d) thrombin

Last Answer : ANSWER: D -- Thrombin

In blood, which anticoagulant substance found

Description : In blood, which anticoagulant substance found

Last Answer : Heparin

It causes clotting of blood - (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above

Description : It causes clotting of blood - (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above

Last Answer : (1) Thrombin Explanation: There are two major facets of the clotting mechanism - the platelets, and the thrombin system. The thrombin system consists of several blood proteins that, when bleeding occurs, become ... called fibrin. Red blood cells become caught up in the web, and a "red clot" forms.

A patient who has been taking quantities of aspirin might show increased post operative bleeding because aspirin inhibits:** A. Synthesis of thromboxane A2 and prevents platelet aggregation B. Synthesis of prostacyclin and prevents platelet aggregation C. Synthesis of prostaglandin and prevents production of blood platelets D. Thrombin and prevents formation of the fibrin network E. Increase the absorption of vitamin K and prevents synthesis of blood clotting factors

Description : A patient who has been taking quantities of aspirin might show increased post operative bleeding because aspirin inhibits:** A. Synthesis of thromboxane A2 and prevents platelet aggregation B. ... network E. Increase the absorption of vitamin K and prevents synthesis of blood clotting factors

Last Answer : A. Synthesis of thromboxane A2 and prevents platelet aggregation

It causes clotting of blood (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above

Description : It causes clotting of blood (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above

Last Answer : Thrombin

Which one of the following anticoagulant is added in blood during storage ?

Description : Which one of the following anticoagulant is added in blood during storage ?

Last Answer : Which one of the following anticoagulant is added in blood during storage ? A. Sodium carbonate ... oxalate C. Sodium chloride D. Sodium hydroxide

Which of the following is an anticoagulant and checks blood coagulation in blood vessels?

Description : Which of the following is an anticoagulant and checks blood coagulation in blood vessels?

Last Answer : Which of the following is an anticoagulant and checks blood coagulation in blood vessels? A. Prothrombin B. Globulin C. Thromboplatin D. Heparin

Which one is the common anticoagulant used for preserving blood?

Description : Which one is the common anticoagulant used for preserving blood?

Last Answer : Which one is the common anticoagulant used for preserving blood? A. NaCl B. Sodium oxalate C. KCl D. Thromboplastin

What is the function of Fibrinogen in blood? -Biology

Description : What is the function of Fibrinogen in blood? -Biology

Last Answer : answer:

Which one of the following is correct? (a) Lymph = Plasma + RBC + WBC (b) Blood = Plasma + RBC + WBC + Platelets (c) Plasma = Blood – Lymphocytes (d) Serum = Blood + Fibrinogen

Description : Which one of the following is correct? (a) Lymph = Plasma + RBC + WBC (b) Blood = Plasma + RBC + WBC + Platelets (c) Plasma = Blood – Lymphocytes (d) Serum = Blood + Fibrinogen

Last Answer : (b) Blood = Plasma + RBC + WBC + Platelets

Match the items given in column I with those in column II and select the correct option given below. Column I Column II A. Fibrinogen (i) Osmotic balance B. Globulin (ii) Blood clotting C. Albumin (iii)Defence mechanism A B C (a) (iii) (ii) (i) (b) (i) (ii) (iii) (c) (i) (iii) (ii) (d) (ii) (iii) (i)

Description : Match the items given in column I with those in column II and select the correct option given below. Column I Column II A. Fibrinogen (i) Osmotic balance B. Globulin (ii) Blood clotting C. Albumin (iii)Defence mechanism A B C (a) ( ... i) (b) (i) (ii) (iii) (c) (i) (iii) (ii) (d) (ii) (iii) (i)

Last Answer : (d) (ii) (iii) (i)

Which of the following is not found in blood? a) fibrinogen b) glucose c) urea d) glycogen

Description : Which of the following is not found in blood? a) fibrinogen b) glucose c) urea d) glycogen

Last Answer : ANSWER: D -- GLYCOGEN

Polyadenylate tail is not present in mRNA synthesising (A) Globin (B) Histone (C) Apoferritin (D) Growth hormone

Description : Polyadenylate tail is not present in mRNA synthesising (A) Globin (B) Histone (C) Apoferritin (D) Growth hormone

Last Answer : Answer : B

Number of chains in globin part of normal Hb: (A) 1 (B) 2 (C) 3 (D) 4

Description : Number of chains in globin part of normal Hb: (A) 1 (B) 2 (C) 3 (D) 4

Last Answer : Answer : D

The main protein found in milk is (1) Albumin (2) Globulin (3) Globin (4) Casein

Description : The main protein found in milk is (1) Albumin (2) Globulin (3) Globin (4) Casein

Last Answer : (4) Casein Explanation: The major proteins in milk are casein and whey. These two milk proteins are both excellent sources of all the essential amino acids, but they differ in one ... food source, casein supplies amino acids, carbohydrates, and the two inorganic elements calcium and phosphorus.

The protein present in the finger nail is (1) Actin (2) Myosin (3) Globin (4) Keratin

Description : The protein present in the finger nail is (1) Actin (2) Myosin (3) Globin (4) Keratin

Last Answer : (4) Keratin Explanation: Keratin is a fibrous protein making up most cells found in our nails and hair and the epidermis layer of our skin. It also makes up fish scales and crustacean shells, bird feathers and beaks, and animal horns and hooves.

. Sickle-cell anaemia is (a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin (b) caused by a change in a single base pair of DNA (c) characterized by elongated sickle like RBCs with a nucleus (d) an autosomal linked dominant trait.

Description : . Sickle-cell anaemia is (a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin (b) caused by a change in a single base pair of DNA (c) characterized by elongated sickle like RBCs with a nucleus (d) an autosomal linked dominant trait.

Last Answer : (b) caused by a change in a single base pair of DNA

Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b) Thalassemia is due to less synthesis of globin molecules. (c) Sickle cell anaemia is due to a quantitative problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.

Description : Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b ... problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.

Last Answer : (b) Thalassemia is due to less synthesis of globin molecules

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2) Thalassemia is due to less synthesis of globin molecules (3) Sickel cell anemia is due to a quantitative problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis

Description : Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2 ... problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis

Last Answer : (2) Thalassemia is due to less synthesis of globin molecules

The main protein found in milk is ______ (1) Albumin (2) Globulin (3) Globin (4) Casein

Description : The main protein found in milk is ______ (1) Albumin (2) Globulin (3) Globin (4) Casein

Last Answer : Casein

The protein present in the finger nail is (1) Actin (2) Myosin (3) Globin (4) Keratin

Description : The protein present in the finger nail is (1) Actin (2) Myosin (3) Globin (4) Keratin

Last Answer : Keratin

Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin react with plasma protein in the presece of

Description : Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin react with plasma protein in the presece of

Last Answer : Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin ... If both Assertion & Reason are false.

Which of the following substances, not normally present in the circulation, trigger the initiating events in the hemostatic process? a. Thrombin b. Platelet factor 3 c. Tissue factor d. Collagen

Description : Which of the following substances, not normally present in the circulation, trigger the initiating events in the hemostatic process? a. Thrombin b. Platelet factor 3 c. Tissue factor d. Collagen

Last Answer : Answer: c, d The initiating agents for hemostasis involve two substances that are not normally present in the circulation-collagen and tissue factor. Tissue factor is released from ... phospholipid surface to form the so-called prothrombinase complex which catalyzes the formation of thrombin

Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for bleeding disorders present in all patients c. Laboratory tests reveal a prolongation of aPTT, prothrombin time (PT), thrombin clotting time and platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal

Description : Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for ... platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal

Last Answer : Answer: a, d Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII although 0% of cases are secondary to spontaneous mutation. The incidence of this abnormality is ... factor levels as low as 1% have been noted and patients are at risk for spontaneous bleeding

An anticoagulant is

Description : An anticoagulant is

Last Answer : An anticoagulant is A. Heparin B. Hirudin C. EDTA D. All the above

An anticoagulant is

Description : An anticoagulant is

Last Answer : An anticoagulant is A. Heparin B. Hirudin C. EDTA D. All the above

The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration of warfarin? a. An important complication of warfarin therapy is skin necrosis in patients with protein C deficiency b. Warfarin interferes with vitamin K dependent clotting factors II, VII, IX, X c. For effective anticoagulation the prothrombin time (PT) should be kept at 2 control d. It is recommended that warfarin be continued for at least one year after initial episode of deep venous thrombosis

Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis

Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time

A patient on oral anticoagulant therapy is commenced on sulfamethoxazoletrimethoprim, double-strength twice daily. One may expect to see the international normalized ratio (a) Increase (b) Decrease (c) Remain unchanged

Description : A patient on oral anticoagulant therapy is commenced on sulfamethoxazoletrimethoprim, double-strength twice daily. One may expect to see the international normalized ratio (a) Increase (b) Decrease (c) Remain unchanged

Last Answer : Ans: A

A patient to be commenced on oral anticoagulant therapy for DVT would be treated with (a) Oral anticoagulant therapy with warfarin for a goal intenational normalized ration (INR) of 2–3 (b) Oral anticoagulant therapy with warfarin for a goal INR of 2.5–3.5 (c) Oral anticoagulant therapy with aspirin for a goal INR of 2–3

Description : A patient to be commenced on oral anticoagulant therapy for DVT would be treated with (a) Oral anticoagulant therapy with warfarin for a goal intenational normalized ration (INR) of 2-3 (b) Oral anticoagulant therapy ... of 2.5-3.5 (c) Oral anticoagulant therapy with aspirin for a goal INR of 2-3

Last Answer : Ans: A

Name the anticoagulant present in leech?

Description : Name the anticoagulant present in leech?

Last Answer : Hirudin

Anticoagulant medication is indicated in: A. Immobilized elederly patients B. Buerger’s disease C. Stroke due to cerebral thrombosis D. All of the above

Description : Anticoagulant medication is indicated in: A. Immobilized elederly patients B. Buerger’s disease C. Stroke due to cerebral thrombosis D. All of the above

Last Answer : A. Immobilized elederly patients

You are treating a patient of deep vein thrombosis with warfarin. What value of International normalized ratio (INR) will you attempt by adjusting dose of the anticoagulant for an adequate therapeutic effect: A. 1.2 – 1.5 B. 1.3 – 1.7 C. 1.5 – 2.0 D. 2.0 – 3.0

Description : You are treating a patient of deep vein thrombosis with warfarin. What value of International normalized ratio (INR) will you attempt by adjusting dose of the anticoagulant for an adequate therapeutic effect: A. 1.2 – 1.5 B. 1.3 – 1.7 C. 1.5 – 2.0 D. 2.0 – 3.0

Last Answer : D. 2.0 – 3.0

The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days C. Their dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

Description : The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their ... dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

Last Answer : A. They interfere with an early step in the synthesis of clotting factors