Description : A patient to be commenced on oral anticoagulant therapy for DVT would be treated with (a) Oral anticoagulant therapy with warfarin for a goal intenational normalized ration (INR) of 2-3 (b) Oral anticoagulant therapy ... of 2.5-3.5 (c) Oral anticoagulant therapy with aspirin for a goal INR of 2-3
Last Answer : Ans: A
Description : You are treating a patient of deep vein thrombosis with warfarin. What value of International normalized ratio (INR) will you attempt by adjusting dose of the anticoagulant for an adequate therapeutic effect: A. 1.2 – 1.5 B. 1.3 – 1.7 C. 1.5 – 2.0 D. 2.0 – 3.0
Last Answer : D. 2.0 – 3.0
Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/ ... (a) Sublingual (b) Oral (c) Intravenous bolus injection (d) Slow intravenous infusion
Last Answer : Ans: D
Description : A 55-year-old patient currently receiving other drugs for another condition is to be started on diuretic therapy for mild heart failure. Thiazides are known to reduce the excretion of (a) Diazepam (b) Fluoxetine (c) Imipramine (d) Lithium (e) Potassium
Description : The feed to fractionating column is changed from saturated vapour to saturated liquid. If the separation and reflux ratio remains unchanged, the number of ideal stages will (A) Increase (B) Decrease (C) Remain same (D) Depend on saturated boiling point; may increase or decrease
Last Answer : (A) Increase
Description : Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension ... (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia
Last Answer : Ans: E
Description : In a co-current double pipe heat exchanger used for condensing saturated steam over the inner tube, if the entrance and exit conditions of the coolant are interchanged, then the rate of condensation ... Decrease (C) Remain unchanged (D) Either increase or decrease; depends on the coolant flow rate
Last Answer : (C) Remain unchanged
Description : In a patient receiving digoxin for congestive heart failure, condition that may facilitate the appearance of toxicity include (a) Hyperkalemia (b) Hypernatremia (c) Hypocalcemia (d) Hypomagnesemia (e) All of the above
Description : Which of the following is not an attribute of amlodipine ? (a) High and consistent oral bioavailability (b) Large volume of distribution (c) Generation of an active metabolite (d) Long elimination half-life
Last Answer : Ans: C
Description : Glyceryl trinitrate is administratered by all of the following routes except (a) Oral (b) Sublingual (c) Intramuscular (d) Intravenous
Description : The oral absorption of following osmotic diuretic is negligible (a) Glycerin (b) Mannitol (c) Isosorbide (d) All of the above
Last Answer : Ans: B
Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis
Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time
Description : As the reflux ratio, in a continuous counter-current extraction is increased, the number of stages (A) Increase (B) Decrease (C) Remain unchanged
Last Answer : (B) Decrease
Description : The ideal efficiency of a Brayton cycle with regeneration, with increase in pressure ratio will (a) increase (b) decrease (c) remain unchanged (d) increase/decrease depending on ap-plication (e) unpredictable. “
Last Answer : Answer : b
Description : Hypothyroidism is a possible consequence of prolonged therapy with (a) Procainamide (b) Mexiletine (c) Sotalol (d) Amiodarone
Description : Because of proven beneficial effects on “cardiac remodeling”, these agents are now indicated as first line therapy in CHF patients. Which of the following is representative of this group of drugs? (a) Hydrochlorothiazide (b) Enalapril (c) Furosemide (d) Carvedilol (e) Bumetanide
Description : Maximal medical therapy for treating angina pectoris is represented by which of the following choices? (a) Diltiazem, verapamil, nitroglycerin (b) Atenolol, isoproterenol, diltiazem (c) Verapamil, nifedipine, propranolol (d) Isosorbide, atenolol, diltiazem (e) Nitroglycerin, isosorbide, atenolol
Description : At constant temperature, the thermal conductivities of gases__________ with rise in pressure. (A) Decrease (B) Increase (C) Remain unchanged (D) May increase or decrease; depends on the pressure
Last Answer : (A) Decrease
Description : If the spring mass system with m and spring stiffness k is taken to very high altitude, the natural frequency of longitudinal vibrations * 1 point (A) increases (B) decreases (C) remain unchanged (D) may increase or decrease depending upon the value of the mass
Last Answer : (C) remain unchanged
Description : If the spring mass system with m and spring stiffness k is taken to very high altitude , the natural frequency of longitudinal vibrations A) Increases B) Decreases C) Remain unchanged D) May be increase or decrease depending upon the value of the mass
Last Answer : C) Remain unchanged
Description : With increase in calorific value of fuels, their adiabatic flame temperatures (A) Increase (B) Decrease (C) Remain unchanged (D) May increase or decrease; depends on the quantity of products of combustion
Last Answer : (D) May increase or decrease; depends on the quantity of products of combustion
Description : If consumer’s income increases, the demand for normal product X (a) will remain unchanged (b)will necessarily increase © will necessarily decrease (d) may increase or decrease
Last Answer : (b)will necessarily increase
Description : Propranolol should not be prescribed for a patient of angina pectoris who is already receiving (a) Nifedipine (b) Felodipine (c) Verapamil (d) Isosorbide mononitrate
Description : A patient suffers from spisodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from (a) Angina pectoris (b) Biliary colic (c) Esophageal spasm (d) All of the above
Description : Quinidine can cause paradoxical tachycardia in a patient of (a) Stick sinus syndrome (b) Auricular extrasystoles (c) Auricular fibrillation (d) Ventricular extrasystoles
Description : Situations that predispose a digitalistreated patient to toxicity include (a) Hypercalcemia (b) Hyperkalemia (c) Hypermagnesemia
Description : For treating the patient with congestive heart failure (CHF), which of the following dosages of dopamine is selected for its positive inotropic effects? (a) 2.0 mg/kg/min (b) 5–10 mg/kg/min (c) 10–20 mg/kg/min (d) 40 mg/kg/min (e) 40 mg/kg/min
Description : When digoxin is used in a patient with congestive heart failure (CHF), it works by exerting a positive effect on (a) Stroke volume (b) Total peripheral resistance (c) Heart rate (d) Blood pressure (e) Venous return
Description : Which of the following groups of symptoms is most often associated with a patient who has right-sided heart failure? (a) Nocturia, rales, paroxysmal nocturnal dyspnea (b) Paroxysmal ... distention (e) Paroxysmal nocturnal dyspnea, jugular venous distention, abdominal distention, shortness of breath
Description : A patient receiving a class I antiarrhythmic agent on a chronic basis complains of fatigue, low-grade fever, and joint pain suggestive of systemic lupus erythematosus (SLE). The patient is most likely receiving (a) Lidocaine (b) Procainamide (c) Quinidine (d) Flecainide (e) Propranolol
Description : Regarding verapamil, which one of the following statements is false? (a) Angina pectoris is an important indication for the use of verapamil (b) Contraindicated in the asthmatic patient (c) ... phase of the action potential in AV nodal cells (e) Used in management of supraventricular tachycardias
Description : A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis
Description : A hypertensive patient has been using nifedipine for some time without untoward effects. If he experiences a rapidly developing enhancement of the antihypertensive effect of the drug, it is probably due to ... ) Grapefruit juice (d) Induction of drug metabolism (e) Over - the - counter decongestants
Description : After being counseled about lifestyle and dietary changes, the patient was started on atorvastatin. During his treatment with atorvastatin, it is important to routinely monitor serum concentrations of (a) ... Alanine and aspartate aminotransferase (c) Platelets (d) Red blood cells (e) Uric acid
Description : If the patient has a history of gout, which of the following drugs is most likely to exacerbate this condition? (a) Colestipol (b) Gemfibrozil (c) Lovastatin (d) Niacin (e) Simvastatin
Description : A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while ... therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system
Last Answer : D. Patient has folate reductase abnormality in the nervous system
Description : Antianginal drugs afford the following benefit/benefits (a) Terminate anginal attacks (b) Decrease the frequency of anginal attacks (c) Retard the progression of coronary artery disease (d) Both (a) and (b)
Description : Methylxanthine drugs such as aminophylline cause which one of the following? (a) Vasoconstriction in many vascular beds (b) Decrease in the amount of cAMP in mast cells (c) Bronchodilation (d) Activation of the enzyme phosphodiesterase (e) Sedation
Description : If the temperature inside a room is increased, the relative humidity will ______? (1) increase (2) decrease (3) remain unchanged (4) none of these
Last Answer : (2) decrease Explanation: This is because temperatures in the home can be much different than the temperature outside. This is because of that important relationship between temperature and how much maximum moisture can be in the air.
Description : Which of the following will happen to the alternator frequency if the load is removed from a turbogenerator, whose governor has a 3% speed droop? A. It will remain unchanged. B. It will decrease by approximately 3%. C. It will become variable. D. It will increase.
Last Answer : Answer: D
Description : At constant pressure, with increase of temperature, the dew point will (A) Increase (B) Decrease (C) Remain unchanged (D) Increase/decrease; depends on the temperature
Description : . If a single tube pass heat exchanger is converted to two pass, then for the same flow rate, the pressure drop per unit length in tube side will (A) Increase by 1.8 times (B) Decrease by 2 2 (C) Increase by 2 16 (D) Remain unchanged
Last Answer : (C) Increase by 2 16
Description : If generally interest rates in nation increase, a corporate bond with a fixed interest rate will usually A. increase in value B. remain unchanged C. decrease in value. D. be returned to corporation.
Last Answer : C. decrease in value.
Description : Friction factor for a hydraulically smooth pipe at NRe = 2100 is f1 . If the pipe is further smoothened (i.e., roughness is reduced), the friction factor at the same value of NRe , will (A) Increase (B) Decrease (C) Remain unchanged (D) Increase or decrease depending on the pipe material
Description : Two fluids are flowing through two similar pipes of the same diameter. The Reynold's number is same. For the same flow rate if the viscosity of a fluid is reduced to half the value of the ... (A) Increase (B) Decrease (C) Remain unchanged (D) Data insufficient to predict relative pressure drop
Description : An isothermal irreversible reaction is being carried out in an ideal tubular flow reactor. The conversion in this case will __________ with decrease in space time. (A) Increase (B) Increase exponentially (C) Decrease (D) Remain unchanged
Last Answer : (C) Decrease
Description : The melting points of aldehydes and ketones tend to : (a) decrease with increasing molecular weight. (b) increase with increasing molecular weight. (c) remain unchanged with increasing molecular weight. (d) be unpredictable due to resonance
Last Answer : increase with increasing molecular weight.
Description : Tea kept in a thermos flask is vigorously shaken. If the tea is considered as a system, then its temperature will (A) Increase (B) Decrease (C) Remain unchanged (D) First fall and then rise
Description : In a Rankine cycle, with the maximum steam temperature being fixed from metallurgical considerations, as the boiler pressure increases (a) The condenser load will increase [IES-1997] (b) The ... The quality of turbine exhaust will increase (d) The quality of turbine exhaust will remain unchanged
Last Answer : (b) The quality of turbine exhaust will decrease
Description : With an increase in size of tube, the rise or depression of liquid in the tube due to surface tension will (A) Decrease (B) Increase (C) Remain unchanged (D) Depend upon the characteristics of liquid
Last Answer : Answer: Option A