Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of prothrombin to thrombin

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Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of ... . If both Assertion & Reason are false.

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Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa

Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi

Description : As thrombin generation proceeds, the body has natural anticoagulant systems opposing further thrombus formation. Natural anticoagulants include: a. Tissue plasminogen activator (TPA) b. Antithrombin III c. Activated protein C d. Heparin cofactor II

Last Answer : Answer: b, c, d Just as thrombin generation is the key to coagulation, antithrombin III is the most central anticoagulant proteins. This glycoprotein binds to thrombin, preventing its removal of ... in the body. Therefore, TPA is part of the fibrinolytic system rather than a natural anticoagulant

Description : Which is the anticoagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin

Last Answer : (2) Heparin Explanation: Heparin, a highly sulfated glycosaminoglycan, is widely used as an inject able anticoagulant, and has the highest negative charge density of any known ... because blood anti-coagulation is achieved mostly by heparin sulfate proteoglyeans derived from endothelial cells.

Description : Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning ... is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascular operations

Last Answer : Answer: a, c, d Coagulation tests include prothrombin time (PT), which measures the intrinsic and extrinsic pathways of fibrinogen production and is the most common method for ... more while for peripheral vascular applications, values of 250 seconds or greater are considered appropriate

Description : Blood does not clot in the blood vessels due to the presence of – (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Last Answer : (3) Heparin Explanation: There are two major facets of the clotting mechanism — the platelets, and the thrombin system. The thrombin system consists of several blood proteins that, when bleeding occurs, become activated.

Description : Blood does not clot in the blood vessels due to the presence of (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin

Last Answer : Thrombin

Description : Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin react with plasma protein in the presece of

Last Answer : Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin ... If both Assertion & Reason are false.

Description : Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for ... platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal

Last Answer : Answer: a, d Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII although 0% of cases are secondary to spontaneous mutation. The incidence of this abnormality is ... factor levels as low as 1% have been noted and patients are at risk for spontaneous bleeding

Description : Vitamin K is required for (a) change of prothrombin into thrombin (b) synthesis of prothrombin (c) change of fibrinogen to fibrin (d) formation of thromboplastin.

Last Answer : (b) synthesis of prothrombin

Description : The standard management oral anticoagulant therapy for chronic treatment of venous thromboembolism is with the drug warfarin. Which of the following statement(s) is/are true concerning the administration ... warfarin be continued for at least one year after initial episode of deep venous thrombosis

Last Answer : Answer: a, b Warfarin interferes with the vitamin K dependent clotting factors II, VII, IX and X, protein C, and protein S. An important complication of warfarin is skin ... the benefit from anticoagulant therapy and thus is the basis for discontinuing warfarin administration at this time

Description : The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their ... dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

Last Answer : A. They interfere with an early step in the synthesis of clotting factors

Description : Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous ... aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

Last Answer : Answer: a, b, c Low-dose heparin is thought to protect against venous thrombosis through three different mechanisms. First, antithrombin III activity with its inhibition of activated Factor X is ... release reaction. The standard doses of heparin administered (5000 units bid) does not affect aPTT

Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Last Answer : Ans: A

Description : The following are true about blood coagulation: a. heparin inhibits blood coagulation through its interference with vitamin K metabolism in the liver b. addition of vitamin K to freshly drawn ... delays clotting c. thrombin converts fibrinogen to fibrin d. platelets are essential for blood clot

Last Answer : thrombin converts fibrinogen to fibrin

Description : Which is the anti-coagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin

Last Answer : Heparin

Description : During hemdialysis process I. blood drained from a conveniend artery and anticoagulant is added (heparin). II. Removal of nitrogenous waste from blood

Last Answer : During hemdialysis process I. blood drained from a conveniend artery and anticoagulant is added (heparin). II. ... D. `I rarr IV rarr II rarr III`

Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin ?

Last Answer : Which type of white blood cells are concerned with the release of histamine and the natural ... Eosinophils B. Monocytes C. Neutrophils D. Basophils

Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin? (a) Eosinophils (b) Monocytes (c) Neutrophils (d) Basophils

Last Answer : d) Basophils

Description : The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation ... active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro

Last Answer : C. Heparin is the physiologically active circulating anticoagulant

Description : A patient who has been taking quantities of aspirin might show increased post operative bleeding because aspirin inhibits:** A. Synthesis of thromboxane A2 and prevents platelet aggregation B. ... network E. Increase the absorption of vitamin K and prevents synthesis of blood clotting factors

Last Answer : A. Synthesis of thromboxane A2 and prevents platelet aggregation

Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function

Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction

Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine

Last Answer : Ans: D

Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin

Last Answer : assess the extrinsic pathway of the blood coagulation cascade

Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.

Description : Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin

Last Answer : B. Affects extrinsic system and decreases prothrombin time

Description : Patient on anti-coagulant therapy requires an extraction to be performed. Which of the following is NOT true: A. Minor post operative bleedings can be reduced somehow by using tranexamic acid B. ... takes at least 8 hours for heparin to take effects D. Heparin should be administered sub-cutaneous

Last Answer : C. It takes at least 8 hours for heparin to take effects

Description : Low doses of heparin prolong: A. Bleeding time B. Activated partial thromboplastin time C. Prothrombin time D. Both ‘B’ and ‘C’

Last Answer : B. Activated partial thromboplastin time

Description : Blood fails to clot white flowing in the blood vessel because of the presence of (1) Heparin (2) Prothrombin (3) Haemoglobin (4) Hirudin

Last Answer : Heparin

Description : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in Blood vessels

Last Answer : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in ... D. If both Assertion & Reason are false.

Description : Hemostasis and the cessation of bleeding require which of the following processes? A. Adherence of platelets to exposed subendothelial glycoproteins and collagen with subsequent aggregation of platelets and ... conversion of fibrinogen to fibrin. D. Cross-linking of fibrin by factor XIII.

Last Answer : Answer: ABCD DISCUSSION: Hemostasis requires the interaction of platelets with the exposed subendothelial structures at the site of injury followed by aggregation of more platelets in that area. ... form a stable clot that incorporates the platelet plug and fibrin thrombus into a stable clot

Description : Assertion `:-` ADH prevents diuresis. Reason `:-` ADH also affect the kidney function by its constrictory effects on blood vessels.

Last Answer : Assertion `:-` ADH prevents diuresis. Reason `:-` ADH also affect the kidney function by its ... . D. If both Assertion & Reason are false.

Description : Assertion : Presence of zona pallucida over the fertilized ovum prevents ectopic pregnancy . Reason : Zona pellucida helps the ovum to penetrate endom

Last Answer : Assertion : Presence of zona pallucida over the fertilized ovum prevents ectopic pregnancy . Reason : Zona ... . If both Assertion & Reason are False.

Description : Assertion: Copper-T is an effectie contraceptive device in human females. Reason: Copper-T prevents passage of sperms from vagina upwards into fallopi

Last Answer : Assertion: Copper-T is an effectie contraceptive device in human females. Reason: Copper-T prevents ... If both the assertion and resson are false.

Description : Assertion : Chorionic gonadotrophin prevents corpus luteum from involuting. Reason : It has the property similar to luteinzing hormone.

Last Answer : Assertion : Chorionic gonadotrophin prevents corpus luteum from involuting. Reason : It has the property ... If both Assertion and Reason are false.

Description : Assertion : Lycaenops is a mammals - like reptile. Reason : Mammal - like reptiles originated in the Permian period.

Last Answer : Assertion : Lycaenops is a mammals - like reptile. Reason : Mammal - like reptiles originated in the ... D. If both Assertion and Reason are false.

Description : Assertion : The duct - billed Platypus and the spiny anteater, both are egg - laying animals yet are grouped under mammals. Reason : Both of them have

Last Answer : Assertion : The duct - billed Platypus and the spiny anteater, both are egg - laying animals yet ... false D. If both Assertion and Reason are false.

Description : Assertion :- The aquatic mammals like Dolphins whales etc. do not contain gill slits. Reason : Their adaptation to aquatic life secondary.

Last Answer : Assertion :- The aquatic mammals like Dolphins whales etc. do not contain gill slits. Reason : Their ... . D. If both Assertion & Reason are false.

Description : Assertion :- All mammals like whales, bats cheetah and human etc. share similarities in the pattern of bonse of forelimbs. Reason :- Eutherians show g

Last Answer : Assertion :- All mammals like whales, bats cheetah and human etc. share similarities in the pattern of ... . D. If both Assertion & Reason are false.

Description : Assertion :- Due to continental drift pouched mammals of Australia survived. Reason :- There is lack of competition from any other mammal.

Last Answer : Assertion :- Due to continental drift pouched mammals of Australia survived. Reason :- There is lack of ... D. If both Assertion & Reason are false.

Description : Assertion : All Eutherian are placental mammals . Reason : All placental mammals have menstrual

Last Answer : Assertion : All Eutherian are placental mammals . Reason : All placental mammals have menstrual A. If ... D. If both Assertion & Reason are False.

Description : In blood, which anticoagulant substance found

Last Answer : Heparin

Description : Photographic plates are covered with black paper because (a) the cellulose acetate of the paper must remain fresh (b) sunlight is easily absorbed by black paper and it helps develop the film ... paper prevents contact with light (d) the conversion of silver bromide to metallic silver is essential

Last Answer : Ans:(c)

Description : Prothrombin is found in `:-`

Last Answer : Prothrombin is found in `:-` A. Intestine and helps in cellulose digestion B. Liver and helps in ... red colour D. Blood and helps in blood clotting

Description : Which of the following substances, not normally present in the circulation, trigger the initiating events in the hemostatic process? a. Thrombin b. Platelet factor 3 c. Tissue factor d. Collagen

Last Answer : Answer: c, d The initiating agents for hemostasis involve two substances that are not normally present in the circulation-collagen and tissue factor. Tissue factor is released from ... phospholipid surface to form the so-called prothrombinase complex which catalyzes the formation of thrombin

Description : It causes clotting of blood - (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above

Last Answer : (1) Thrombin Explanation: There are two major facets of the clotting mechanism - the platelets, and the thrombin system. The thrombin system consists of several blood proteins that, when bleeding occurs, become ... called fibrin. Red blood cells become caught up in the web, and a "red clot" forms.

Description : When a wound occurs in humans, the platelets in th blood activate a substance which starts the clotting process. The substance which starts the clotting is: a) adenosine (pron: ah-den-ah-seen) b) histamine c) lecithin (pron: less-ah-thin) d) thrombin

Last Answer : ANSWER: D -- Thrombin

Description : It causes clotting of blood (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above

Last Answer : Thrombin

Description : Which one of the following anticoagulant is added in blood during storage ?

Last Answer : Which one of the following anticoagulant is added in blood during storage ? A. Sodium carbonate ... oxalate C. Sodium chloride D. Sodium hydroxide

Description : Which of the following is an anticoagulant and checks blood coagulation in blood vessels?

Last Answer : Which of the following is an anticoagulant and checks blood coagulation in blood vessels? A. Prothrombin B. Globulin C. Thromboplatin D. Heparin

Description : An anticoagulant is

Last Answer : An anticoagulant is A. Heparin B. Hirudin C. EDTA D. All the above