A newborn was diagnosed as having a congenital abnormality that resulted in transposition of her great arteries. While preparing the infant for surgery, the medical team needed to keep the ductus arteriosus open. They did this by infusing (a) Cortisol (b) Indomethacin (c) Ketorolac (d) Misoprostol (e) Tacrolimus

A newborn was diagnosed as having a congenital abnormality that resulted in transposition of her great arteries. While preparing the infant for surgery, the medical team needed to keep the ductus arteriosus open. They did this by infusing (a) Cortisol (b) Indomethacin (c) Ketorolac (d) Misoprostol (e) Tacrolimus
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Ans: D
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A 65-year-old is interested in taking ginkgo. Which of the following statements is correct regarding ginkgo? (a) Ginkgo is contraindicated in diabetes and pregnancy (b) There is a drug-herb interaction between ginkgo and aspirin (c) Toxic effects include hypertension and cardiac arrest (d) There is a drug-herb interaction between ginkgo and phenelzine (e) Ginkgo is contraindicated in patients with gallstone pain

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Last Answer : Ans: B

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The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine

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Last Answer : Ans: D

In addition to their ability to decrease inflammatory prostaglandin synthesis, some non-steroidal anti-inflammatory drugs (NSAIDs) may owe part of their effects to their ability to (a) Inhibit leukocyte migration (b) Inhibit leukotriene synthesis (c) Stabilize lysosmal membranes (d) All of the above (e) None of the above

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Last Answer : Ans: D

Which of the following medications would represent arthritis therapy that is least likely to cause gastric ulceration? (a) Aspirin (b) Acetaminophen (c) Piroxicam (d) Meclofenamate (e) Rofecoxib

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Last Answer : Ans: E

Patients taking chronic doses of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) should periodically be screened for which of the following toxicities? (a) Nephrotoxicity (b) Peripheral neuropathy (c) Cardiotoxicity (d) All of the above (e) None of the above

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The action of aspirin that results in its greater efficacy as an antithrombotic (anti-platelet) drug is its ability to (a) Inhibit lipoxygenase as well as cyclooxygenase (b) Selectively inhibit cyclooxygenase I (c) Inhibit leukocyte migration (d) Promote uric acid excretion (e) Acetylate cyclooxygenase

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Last Answer : Ans: E

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Last Answer : Ans: D

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Last Answer : Ans: C

Cyclooxygenase-1 and –2 are responsible for (a) The synthesis of prostaglandins from arachidonate (b) The synthesis of leukotrienes from arachidonate (c) The conversion of ATP to cAMP (d) The metabolic degradation of cAMP (e) The conversion of GTP to cGMP

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Last Answer : Ans: A

A drug that decreases blood pressure and has analgesic and spasmolytic effects when given intrathecally is (a) Atenolol (b) Clonidine (c) Morphine (d) Nitroprusside (e) Prazosin

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Last Answer : Ans: B

Accidental poisonings are common with both aspirin and ibuprofen, two OC drugs available in tasty chewable tablets. In cases of overdose, aspirin is more likely than ibuprofen to cause (a) Autonomic Instability (b) Hepatic necrosis (c) Metabolic acidosis (d) Thrombocytopenia (e) Ventricular arrhythmias

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Last Answer : Ans: C

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Last Answer : Ans: D

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Last Answer : Ans: E