Aspirin is contraindicated in pregnant women near term because: A. Labour may be delayed and prolonged B. Blood loss during delivery may be more C. Foetus may suffer premature closure of ductus arteriosus D. All of the above risks

 Aspirin is contraindicated in pregnant women near term because: A. Labour may be delayed and prolonged B. Blood loss during delivery may be more C. Foetus may suffer premature closure of ductus arteriosus D. All of the above risks
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1 Answer

Answer :

D. All of the above risks
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Related questions

Inhibition of prostaglandin synthesis does not underlie the following action of aspirin: A. Analgesia B. Closure of patent ductus arteriosus C. Hyperventilation D. Bleeding tendency

Description : Inhibition of prostaglandin synthesis does not underlie the following action of aspirin: A. Analgesia B. Closure of patent ductus arteriosus C. Hyperventilation D. Bleeding tendency

Last Answer : C. Hyperventilation

Prostaglandins play pathophysiological role in the following except: A. Patency of ductus arteriosus B. Regulation of renal tubular salt absorption C. Ventricular remodeling after myocardial infarction D. Initiation of labour

Description :  Prostaglandins play pathophysiological role in the following except: A. Patency of ductus arteriosus B. Regulation of renal tubular salt absorption C. Ventricular remodeling after myocardial infarction D. Initiation of labour

Last Answer : C. Ventricular remodeling after myocardial infarction 

Fexofenadine differs from terfenadine in that: A. It undergoes high first pass metabolism in liver B. It is a prodrug C. It does not block cardiac delayed rectifier K+ channels D. It has high affinity for central H1 receptors

Description : Fexofenadine differs from terfenadine in that: A. It undergoes high first pass metabolism in liver B. It is a prodrug C. It does not block cardiac delayed rectifier K+ channels D. It has high affinity for central H1 receptors

Last Answer : C. It does not block cardiac delayed rectifier K+ channels

Prolonged airway hyperreactivity is characteristically caused by: A. Histamine B. Prostaglandin E2 C. Platelet activating factor D. Bradykinin

Description :  Prolonged airway hyperreactivity is characteristically caused by: A. Histamine B. Prostaglandin E2 C. Platelet activating factor D. Bradykinin

Last Answer : C. Platelet activating factor

In mammalian embryo the pulmonary aorta communicates with carotico-systemic aorta by a narrow ductus arteriosus, in the adult this connection closes l

Description : In mammalian embryo the pulmonary aorta communicates with carotico-systemic aorta by a narrow ductus arteriosus, in the adult this connection closes l

Last Answer : In mammalian embryo the pulmonary aorta communicates with carotico-systemic aorta by a narrow ductus ... C. Ligamentum arteriosus D. None of these

Patent ductus arteriosus?

Description : Patent ductus arteriosus?

Last Answer : DefinitionPatent ductus arteriosus (PDA) is a condition in which a blood vessel called the ductus arteriosus fails to close normally in an infant soon after birth. (The word "patent" means open.)The ... within a couple of days. If the ductus arteriosus does not close, there will be abnormal bloo

A newborn was diagnosed as having a congenital abnormality that resulted in transposition of her great arteries. While preparing the infant for surgery, the medical team needed to keep the ductus arteriosus open. They did this by infusing (a) Cortisol (b) Indomethacin (c) Ketorolac (d) Misoprostol (e) Tacrolimus

Description : A newborn was diagnosed as having a congenital abnormality that resulted in transposition of her great arteries. While preparing the infant for surgery, the medical team needed to keep the ductus arteriosus ... by infusing (a) Cortisol (b) Indomethacin (c) Ketorolac (d) Misoprostol (e) Tacrolimus

Last Answer : Ans: D

In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is: A. Acid-base and electrolyte disturbances B. Hypersensitivity and idiosyncratic reactions C. Gastric mucosal damage D. Salicylism

Description :  In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is: A. Acid-base and electrolyte disturbances B. Hypersensitivity and idiosyncratic reactions C. Gastric mucosal damage D. Salicylism

Last Answer : C. Gastric mucosal damage

Select the drug which inhibits cyclooxygenase irreversibly: A. Aspirin B. Mephenamic acid C. Naproxen D. Diclofenac

Description : Select the drug which inhibits cyclooxygenase irreversibly: A. Aspirin B. Mephenamic acid C. Naproxen D. Diclofenac

Last Answer : A. Aspirin

Aspirin produces analgesia by: A. Preventing sensitization of peripheral pain receptors B. Affecting gating of pain impulses at spinal level C. Raising pain threshold at subcortical level D. Both ‘A’ and ‘C’ are correct

Description : Aspirin produces analgesia by: A. Preventing sensitization of peripheral pain receptors B. Affecting gating of pain impulses at spinal level C. Raising pain threshold at subcortical level D. Both ‘A’ and ‘C’ are correct

Last Answer : D. Both ‘A’ and ‘C’ are correct

Inhibitors of prostaglandin synthesis share the following features except: A. Prolongation of bleeding time B. Prolongation of prothrombin time C. Prolongation of labour D. Gastric mucosal damage

Description :  Inhibitors of prostaglandin synthesis share the following features except: A. Prolongation of bleeding time B. Prolongation of prothrombin time C. Prolongation of labour D. Gastric mucosal damage

Last Answer : B. Prolongation of prothrombin time

The following drug is used for cervical priming to facilitate labour: A. Oxytocin B. Clomiphene C. Progesterone D. Prostaglandin E2

Description : The following drug is used for cervical priming to facilitate labour: A. Oxytocin B. Clomiphene C. Progesterone D. Prostaglandin E2

Last Answer : D. Prostaglandin E2

A 35-year-old male presented with an attack of acute gout. He was treated with a 10 day course of naproxen. His blood uric acid level is high. What future line of treatment is most appropriate: A. No regular medication. Treat attacks of acute gout when they occur with naproxen. B. Regular long-term treatment with naproxen C. Regular long-term treatment with allopurinol D. Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment

Description : A 35-year-old male presented with an attack of acute gout. He was treated with a 10 day course of naproxen. His blood uric acid level is high. What future line of treatment is ... treatment with allopurinol D. Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment

Last Answer : D. Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment

The nurse providing education regarding sexually transmitted diseases includes which of the following statements regarding herpes virus 2 (herpes genitalis)? a) In pregnant women with active herpes virus, babies delivered vaginally may become infected with the virus. Therefore, a cesarean delivery may be performed if the virus recurs near the time of delivery.

Description : The nurse providing education regarding sexually transmitted diseases includes which of the following statements regarding herpes virus 2 (herpes genitalis)? a) In pregnant women with active herpes virus, babies ... very difficult to kill. Usually, the virus is killed at room temperature by drying.

Last Answer : a) In pregnant women with active herpes virus, babies delivered vaginally may become infected with the virus. Therefore, a cesarean delivery may be performed if the virus recurs near the time of delivery.

Nonsteroidal antiinflammatory drugs are more commonly used than colchicine in acute gout because: A. They are more effective B. They act more rapidly C. They have additional uricosuric action D. They are better tolerated

Description : Nonsteroidal antiinflammatory drugs are more commonly used than colchicine in acute gout because: A. They are more effective B. They act more rapidly C. They have additional uricosuric action D. They are better tolerated

Last Answer : D. They are better tolerated

Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential to cause agranulocytosis C. It has weak analgesic action D. It alters the protein binding and metabolism of many drugs

Description : Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential ... It has weak analgesic action D. It alters the protein binding and metabolism of many drugs

Last Answer : B. It has potential to cause agranulocytosis

Erythromycin should not be given to a patient being treated with terfenadine because: A. Erythromycin induces the metabolism of terfenadine B. Dangerous ventricular arrhythmias can occur C. Terfenadine inhibitis metabolism of erythromycin D. Terfenadine antagonizes the antimicrobial action of erythromycin

Description : Erythromycin should not be given to a patient being treated with terfenadine because: A. Erythromycin induces the metabolism of terfenadine B. Dangerous ventricular arrhythmias ... Terfenadine inhibitis metabolism of erythromycin D. Terfenadine antagonizes the antimicrobial action of erythromycin

Last Answer : B. Dangerous ventricular arrhythmias can occur

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Last Answer : D. Ratio of H1:H2 blockade produced by the drug

Actions of prostaglandin E2 include the following except: A. Fall in blood pressure B. Bronchoconstriction C. Uterine contraction D. Inhibition of gastric acid secretion

Description : Actions of prostaglandin E2 include the following except: A. Fall in blood pressure B. Bronchoconstriction C. Uterine contraction D. Inhibition of gastric acid secretion

Last Answer : B. Bronchoconstriction

The prostanoid that consistently constricts blood vessels is: A. Prostaglandin E2 B. Prostaglandin F2α C. Thromboxane A2 D. Prostacyclin

Description : The prostanoid that consistently constricts blood vessels is: A. Prostaglandin E2 B. Prostaglandin F2α C. Thromboxane A2 D. Prostacyclin

Last Answer : C. Thromboxane

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Last Answer : D. Ratio of H1:H2 blockade produced by the drug

What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition

Aspirin is contraindicated in children suffering from influenza or similar viral infection because of increased risk of: A. Gastric bleeding B. Thrombocytopenia C. Fancony syndrome D. Reye’s syndrome

Description : Aspirin is contraindicated in children suffering from influenza or similar viral infection because of increased risk of: A. Gastric bleeding B. Thrombocytopenia C. Fancony syndrome D. Reye’s syndrome

Last Answer : D. Reye’s syndrome

What is true of disease modifying antirheumatic drugs: A. Their beneficial effect is manifest only after 1-3 months of therapy B. The disease does not recurr once they induce remission C. They are to be used life long D. Concurrent use of more than one disease modifying drug is not recommended

Description : What is true of disease modifying antirheumatic drugs: A. Their beneficial effect is manifest only after 1-3 months of therapy B. The disease does not recurr once they induce remission C. They are to be used life long D. Concurrent use of more than one disease modifying drug is not recommended

Last Answer : A. Their beneficial effect is manifest only after 1-3 months of therapy

Used as a remission inducing agent in rheumatoid arthritis, hydroxychloroquine: A. Is more effective than chloroquine B. Produces a lower incidence of retinal damage than chloroquine C. Is more effective and more toxic than gold D. Both ‘A’ and ‘B’ are correct

Description : Used as a remission inducing agent in rheumatoid arthritis, hydroxychloroquine: A. Is more effective than chloroquine B. Produces a lower incidence of retinal damage than chloroquine C. Is more effective and more toxic than gold D. Both ‘A’ and ‘B’ are correct

Last Answer : B. Produces a lower incidence of retinal damage than chloroquine

Dihydroergotamine (DHE) differs from ergotamine in the following respect: A. It is a more potent oxytocic B. It has antiemetic property C. It has high oral bioavailability D. It is a more potent α adrenergic blocker and less potent vasoconstrictor

Description : Dihydroergotamine (DHE) differs from ergotamine in the following respect: A. It is a more potent oxytocic B. It has antiemetic property C. It has high oral bioavailability D. It is a more potent α adrenergic blocker and less potent vasoconstrictor

Last Answer : D. It is a more potent α adrenergic blocker and less potent vasoconstrictor

With effect from------------------, all Single/Double handed Sub Post Offices, at the time of closure/premature closure of RD/MIS/SCSS accounts will collect closed passbook from the depositor and attach the same with account closure form and send in a manner as prescribed for dispatch of vouchers and LOT to HO. a) 15.2.2008 b) 11.06.2010 c) 23.06.2010 d) None of these

Description : With effect from------------------, all Single/Double handed Sub Post Offices, at the time of closure/premature closure of RD/MIS/SCSS accounts will collect closed passbook from the depositor and attach the same with ... LOT to HO. a) 15.2.2008 b) 11.06.2010 c) 23.06.2010 d) None of these

Last Answer : a) 15.2.2008

Depreciation is defined as A) destruction of a plant in a fire accident B) loss of equipment over time due to wear and tear C) closure of a plant due to labour trouble D) closure of a plant due to lockout

Description : Depreciation is defined as A) destruction of a plant in a fire accident B) loss of equipment over time due to wear and tear C) closure of a plant due to labour trouble D) closure of a plant due to lockout

Last Answer : Answer: B

Topical atropine is contraindicated in: a. Retinoscopy in children b. Iridocyclitis c. Corneal ulcer d. Primary angle closure glaucoma

Description : Topical atropine is contraindicated in: a. Retinoscopy in children b. Iridocyclitis c. Corneal ulcer d. Primary angle closure glaucoma

Last Answer : ANSWER: D

While prescribing a first generation H1 antihistaminic the patient should be advised to avoid: A. Driving motor vehicles B. Consuming processed cheese C. Strenuous physical exertion D. All of the above

Description : While prescribing a first generation H1 antihistaminic the patient should be advised to avoid: A. Driving motor vehicles B. Consuming processed cheese C. Strenuous physical exertion D. All of the above

Last Answer : A. Driving motor vehicles

The conventional H1 antihistaminics possess the following additional properties except: A. Local anaesthetic B. Vasopressor C. Antiarrhythmic D. Catecholamine potentiating

Description : The conventional H1 antihistaminics possess the following additional properties except: A. Local anaesthetic B. Vasopressor C. Antiarrhythmic D. Catecholamine potentiating

Last Answer : B. Vasopressor

The following H1 antihistaminic has additional anti 5-HT, anticholinergic, sedative and appetite stimulating properties: A. Promethazine B. Terfenadine C. Cyproheptadine D. Hydroxyzine

Description : The following H1 antihistaminic has additional anti 5-HT, anticholinergic, sedative and appetite stimulating properties: A. Promethazine B. Terfenadine C. Cyproheptadine D. Hydroxyzine

Last Answer : C. Cyproheptadine

High anticholinergic property is present in the following antihistaminic: A. Diphenhydramine B. Astemizole C. Cetirizine D. Terfenadine

Description : High anticholinergic property is present in the following antihistaminic: A. Diphenhydramine B. Astemizole C. Cetirizine D. Terfenadine

Last Answer : A. Diphenhydramine

The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla

Description : The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla

Last Answer : B. Direct action on vascular smooth muscle causing vasodilatation

Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Last Answer : C. 2-Thiazolyl ethylamine

Autacoids differ from hormones in that: A. Autacoids are involved only in the causation of pathological states B. Autacoids do not have a specific cell/tissue of origin C. Autacoids generally act locally at the site of generation and release D. Both ‘B’ and ‘C’ are correct

Description : Autacoids differ from hormones in that: A. Autacoids are involved only in the causation of pathological states B. Autacoids do not have a specific cell/tissue of origin C. Autacoids generally act locally at the site of generation and release D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Allopurinol has a therapeutic effect in the following conditions except: A. Radiotherapy induced hyperuricaemia B. Hydrochlorothiazide induced hyperuricaemia C. Acute gouty arthritis D. Kala-azar

Description : Allopurinol has a therapeutic effect in the following conditions except: A. Radiotherapy induced hyperuricaemia B. Hydrochlorothiazide induced hyperuricaemia C. Acute gouty arthritis D. Kala-azar

Last Answer : C. Acute gouty arthritis

Allopurinol is indicated in the following category of chronic gout patients: A. Over producers of uric acid B. Under excretors of uric acid C. Those with tophi and/or renal urate stones D. All of the above

Description : Allopurinol is indicated in the following category of chronic gout patients: A. Over producers of uric acid B. Under excretors of uric acid C. Those with tophi and/or renal urate stones D. All of the above

Last Answer : D. All of the above

Select the drug which is used in chronic gout but is not uricosuric: A. Probenecid B. Phenylbutazone C. Sulfinpyrazone D. Allopurinol

Description : Select the drug which is used in chronic gout but is not uricosuric: A. Probenecid B. Phenylbutazone C. Sulfinpyrazone D. Allopurinol

Last Answer : D. Allopurinol

Probenecid has the following action(s): A. Uricosuric B. Analgesic C. Antiinflammatory D. Both ‘A’ and ‘C’

Description : Probenecid has the following action(s): A. Uricosuric B. Analgesic C. Antiinflammatory D. Both ‘A’ and ‘C’

Last Answer : A. Uricosuric

The most important dose-limiting adverse effect of colchicine is: A. Sedation B. Kidney damage C. Diarrhoea D. Muscle paralysis

Description : The most important dose-limiting adverse effect of colchicine is: A. Sedation B. Kidney damage C. Diarrhoea D. Muscle paralysis

Last Answer : C. Diarrhoea

Select the drug which is neither analgesic, nor antiinflammatory, nor uricosuric, but is highly efficacious in acute gout: A. Prednisolone B. Colchicine C. Naproxen D. Sulfinpyrazone

Description : Select the drug which is neither analgesic, nor antiinflammatory, nor uricosuric, but is highly efficacious in acute gout: A. Prednisolone B. Colchicine C. Naproxen D. Sulfinpyrazone

Last Answer : B. Colchicine

Select the first choice drug for acute gout: A. Cochicine B. Indomethacin C. Allopurinol D. Dexamethasone

Description : Select the first choice drug for acute gout: A. Cochicine B. Indomethacin C. Allopurinol D. Dexamethasone

Last Answer : B. Indomethacin

Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive disease C. Only when NSAIDs fail to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication

Description : Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive ... to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication

Last Answer : B. Along with NSAIDs in patients with progressive disease

Sulfasalazine is used in the following disease(s): A. Bacillary dysentery B. Ulcerative colitis C. Rheumatoid arthritis D. Both ‘B’ and ‘C’ are correct

Description : Sulfasalazine is used in the following disease(s): A. Bacillary dysentery B. Ulcerative colitis C. Rheumatoid arthritis D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Among the following, choose the NSAID with the highest COX-2 selectivity: A. Nimesulide B. Nabumetone C. Rofecoxib D. Celecoxib

Description : Among the following, choose the NSAID with the highest COX-2 selectivity: A. Nimesulide B. Nabumetone C. Rofecoxib D. Celecoxib

Last Answer : C. Rofecoxib

The patient taking the following non-steroidal antiinflammatory drug should be cautioned not to drive motor vehicle: A. Celecoxib B. Indomethacin C. Naproxen D. Diclofenac sodium

Description : The patient taking the following non-steroidal antiinflammatory drug should be cautioned not to drive motor vehicle: A. Celecoxib B. Indomethacin C. Naproxen D. Diclofenac sodium

Last Answer : B. Indomethacin

Which of the following analgesics itself frequently causes headache as a side effect: A. Indomethacin B. Mephenamic acid C. Piroxicam D. Metamizol

Description : Which of the following analgesics itself frequently causes headache as a side effect: A. Indomethacin B. Mephenamic acid C. Piroxicam D. Metamizol

Last Answer : A. Indomethacin

The NSAIDs aggravate the following diseases except: A. Hypertension B. Congestive heart failure C. Peptic ulcer D. Chronic gout

Description :  The NSAIDs aggravate the following diseases except: A. Hypertension B. Congestive heart failure C. Peptic ulcer D. Chronic gout

Last Answer : D. Chronic gout

Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they: A. Are antiinflammatory but not analgesic B. Donot bring down fever C. Have no renal effects D. Do not inhibit platelet aggregation

Description :  Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they: A. Are antiinflammatory but not analgesic B. Donot bring down fever C. Have no renal effects D. Do not inhibit platelet aggregation

Last Answer : D. Do not inhibit platelet aggregation