Losartan is a: A. Selective AT1 receptor antagonist B. Selective AT2 receptor antagonist C. Nonselective AT1 + AT2 receptor antagonist D. AT1 receptor partial agonist

Losartan is a:
A. Selective AT1 receptor antagonist
B. Selective AT2 receptor antagonist
C. Nonselective AT1 + AT2 receptor antagonist
D. AT1 receptor partial agonist
by

1 Answer

Answer :

A. Selective AT1 receptor antagonist
by

Related questions

he following is true of desmopressin except: A. It is nonselective V1 and V2 receptor agonist B. It is more potent and longer acting than arginine vasopressin (AVP) C. It is preferred over AVP for treatment of diabetes insipidus D. It can be administered orally

Description : Che following is true of desmopressin except: A. It is nonselective V1 and V2 receptor agonist B. It is more potent and longer acting than arginine vasopressin (AVP) C. It is preferred over AVP for treatment of diabetes insipidus D. It can be administered orally

Last Answer : A. It is nonselective V1 and V2 receptor agonist

Which of the following peptides is a selective vasopressin V2 receptor agonist: A. Arginine vasopressin B. Desmopressin C. Lypessin D. Terlipressin

Description : Which of the following peptides is a selective vasopressin V2 receptor agonist: A. Arginine vasopressin B. Desmopressin C. Lypessin D. Terlipressin

Last Answer : B. Desmopressin

Choose the selective estrogen receptor modulator that is useful in dysfunctional uterine bleeding by acting as estrogen antagonist in endometrium, but does not alter vaginal epithelium or cervical mucus: A. Ormeloxifene B. Tamoxifen C. Centchroman D. Danazol

Description : Choose the selective estrogen receptor modulator that is useful in dysfunctional uterine bleeding by acting as estrogen antagonist in endometrium, but does not alter vaginal epithelium or cervical mucus: A. Ormeloxifene B. Tamoxifen C. Centchroman D. Danazol

Last Answer : . Ormeloxifen

Postural hypotension is a common adverse effect of which one of the following types of drugs ? (a) ACE inhibitors (b) Alpha-receptor blockers (c) Arteriolar dilators (d) ß1 – selective receptor blockers (e) Nonselective ß - blockers

Description : Postural hypotension is a common adverse effect of which one of the following types of drugs ? (a) ACE inhibitors (b) Alpha-receptor blockers (c) Arteriolar dilators (d) ß1 – selective receptor blockers (e) Nonselective ß - blockers

Last Answer : Ans: B

The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis

Description : The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis

Last Answer : C. Naloxone is largely ineffective in reversing its effects

Which of the following is an agonist-antagonist type of opioid analgesic: A. Pethidine B. Pentazocine C. Fentanyl D. Buprenorphine

Description : Which of the following is an agonist-antagonist type of opioid analgesic: A. Pethidine B. Pentazocine C. Fentanyl D. Buprenorphine

Last Answer : B. Pentazocine

Which of the following terms best describes the antagonism of leukotriene’s bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with asthma? (a) Pharmacologic antagonist (b) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist

Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist

Last Answer : Ans: C

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Last Answer : C. Noncompetitive antagonist

A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Description : A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Last Answer : C. Competitive antagonist

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist

Last Answer : C. Noncompetitive antagonist

A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Description : A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist

Last Answer : C. Competitive antagonist

Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Last Answer : C. 2-Thiazolyl ethylamine

The following is a selective 5-HT1D receptor agonist: A. Buspirone B. Ondansetron C. Sumatriptan D. α-methyl 5-HT

Description : The following is a selective 5-HT1D receptor agonist: A. Buspirone B. Ondansetron C. Sumatriptan D. α-methyl 5-HT

Last Answer : C. Sumatriptan

Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Last Answer : C. 2-Thiazolyl ethylamine

The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. It produces physical dependence and suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert

Description : The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. ... suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert

Last Answer : D. It has anxiolytic but no anticonvulsant or muscle relaxant property

Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

Last Answer : D. All of the above

The following is a selective 5-HT4 agonist: A. Buspirone B. Sumatriptan C. Cisapride D. Clozapine

Description : The following is a selective 5-HT4 agonist: A. Buspirone B. Sumatriptan C. Cisapride D. Clozapine

Last Answer : C. Cisapride

Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route

Description : Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route

Last Answer : B. It suppresses postoperative nausea and vomitin

The following is true of clopidogrel except: A. It is a GPIIb/IIIa receptor antagonist B. It inhibits fibrinogen induced platelet aggregation C. It is indicated for prevention of stroke in patients with transient ischaemic attacks D. It is a prodrug

Description : The following is true of clopidogrel except: A. It is a GPIIb/IIIa receptor antagonist B. It inhibits fibrinogen induced platelet aggregation C. It is indicated for prevention of stroke in patients with transient ischaemic attacks D. It is a prodrug

Last Answer : A. It is a GPIIb/IIIa receptor antagonist

The following is a selective α2 adrenoceptor antagonist: A. Prazosin B. Phentolamine C. Yohimbine D. Clonidine

Description : The following is a selective α2 adrenoceptor antagonist: A. Prazosin B. Phentolamine C. Yohimbine D. Clonidine

Last Answer : C. Yohimbine

The following is a selective α 2 adrenoceptor antagonist: A. Prazosin B. Phentolamine C. Yohimbine D. Clonidine

Description : The following is a selective α 2 adrenoceptor antagonist: A. Prazosin B. Phentolamine C. Yohimbine D. Clonidine

Last Answer : C. Yohimbine

Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It is a synthetic atropine substitute used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms

Choose the drug that selectively blocks AT1 subtype of angiotensin receptors: A. Ramipril B. Lovastatin C. Candesartan D. Sumatriptan

Description : Choose the drug that selectively blocks AT1 subtype of angiotensin receptors: A. Ramipril B. Lovastatin C. Candesartan D. Sumatriptan

Last Answer : C. Candesartan

What is true of docetaxel: A. It is used as a reserve drug for refractory breast and ovarian cancer B. It is a selective estrogen receptor modulator used for breast cancer C. It is effective only in estrogen receptor positive breast cancer D. Both 'B' and 'C' are correct

Description : What is true of docetaxel: A. It is used as a reserve drug for refractory breast and ovarian cancer B. It is a selective estrogen receptor modulator used for breast cancer C. It is effective only in estrogen receptor positive breast cancer D. Both 'B' and 'C' are correct

Last Answer : A. It is used as a reserve drug for refractory breast and ovarian cancer

Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

Description : Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

Last Answer : B. Zolpidem

Which of the following is a selective estrogen receptor modulator that improves bone mineral density in postmenopausal women: A. Clomiphene citrate B. Raloxifene C. Ormeloxifene D. Alendronate

Description : Which of the following is a selective estrogen receptor modulator that improves bone mineral density in postmenopausal women: A. Clomiphene citrate B. Raloxifene C. Ormeloxifene D. Alendronate

Last Answer : B. Raloxifene

Which of the following drugs can afford both haemodynamic improvement as well as disease modifying benefits in CHF: A. Furosemide B. Milrinone C. Losartan D. Digoxin

Description : Which of the following drugs can afford both haemodynamic improvement as well as disease modifying benefits in CHF: A. Furosemide B. Milrinone C. Losartan D. Digoxin

Last Answer : C. Losartan

Losartan differs from enalapril in the following respect: A. It does not potentiate bradykinin B. It depresses cardiovascular reflexes C. It impairs carbohydrate tolerance D. It does not have fetopathic potential

Description : Losartan differs from enalapril in the following respect: A. It does not potentiate bradykinin B. It depresses cardiovascular reflexes C. It impairs carbohydrate tolerance D. It does not have fetopathic potential

Last Answer : A. It does not potentiate bradykini

Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they: A. Are antiinflammatory but not analgesic B. Donot bring down fever C. Have no renal effects D. Do not inhibit platelet aggregation

Description :  Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they: A. Are antiinflammatory but not analgesic B. Donot bring down fever C. Have no renal effects D. Do not inhibit platelet aggregation

Last Answer : D. Do not inhibit platelet aggregation

The nonselective MAO inhibitors are not used clinically as antidepressants because of their: A. Low antidepressant efficacy B. Higher toxicity C. Potential to interact with many foods and drugs D. Both 'B' and 'C' are correct

Description : The nonselective MAO inhibitors are not used clinically as antidepressants because of their: A. Low antidepressant efficacy B. Higher toxicity C. Potential to interact with many foods and drugs D. Both 'B' and 'C' are correct

Last Answer : D. Both 'B' and 'C' are correct

Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Last Answer : C. It does not concurrently enhance noradrenaline release

Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Last Answer : C. It does not concurrently enhance noradrenaline release

The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation

Description : The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation

Last Answer : B. Bradycardia

Reserprine, an alkaloid derived from the root of Rauwolfia serpentina (a) Can be used to control hyperglycemia (b) Can cause severe depression of mood (c) Can decrease gastrointestinal secretion and motility (d) Has no cardiac effects (e) A spare receptor agonist

Description : Reserprine, an alkaloid derived from the root of Rauwolfia serpentina (a) Can be used to control hyperglycemia (b) Can cause severe depression of mood (c) Can decrease gastrointestinal secretion and motility (d) Has no cardiac effects (e) A spare receptor agonist

Last Answer : Ans: B

The following is not a feature of competitive antagonists: A. Chemical resemblance with the agonist B. Parallel rightward shift of the agonist log doseresponse curve C. Suppression of maximal agonist response D. Apparent reduction in agonist affinity for the receptor

Description : The following is not a feature of competitive antagonists: A. Chemical resemblance with the agonist B. Parallel rightward shift of the agonist log doseresponse curve C. Suppression of maximal agonist response D. Apparent reduction in agonist affinity for the receptor

Last Answer : C. Suppression of maximal agonist response

The following is not a feature of competitive antagonists: A. Chemical resemblance with the agonist B. Parallel rightward shift of the agonist log doseresponse curve C. Suppression of maximal agonist response D. Apparent reduction in agonist affinity for the receptor

Description : The following is not a feature of competitive antagonists: A. Chemical resemblance with the agonist B. Parallel rightward shift of the agonist log doseresponse curve C. Suppression of maximal agonist response D. Apparent reduction in agonist affinity for the receptor

Last Answer : C. Suppression of maximal agonist response

Oxytremorine is a selective agonist of muscarinic _______ receptors (a) M1 (b) M2 (c) M3 (d) M4

Description : Oxytremorine is a selective agonist of muscarinic _______ receptors (a) M1 (b) M2 (c) M3 (d) M4

Last Answer : Ans: A

Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol

Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol

Last Answer : Ans: E

Select the correct statement about salmeterol. (a) It is a long acting selective ß2 agonist bronchodilator (b) It is a bronchodilator with anti-inflammatory property (c) It is a ß blocker that can be safely given to asthmatics (d) It is an antihistaminic with mast cells stabilizing property

Description : Select the correct statement about salmeterol. (a) It is a long acting selective ß2 agonist bronchodilator (b) It is a bronchodilator with anti-inflammatory property (c) It is a ß blocker that can be safely given to asthmatics (d) It is an antihistaminic with mast cells stabilizing property

Last Answer : Ans: A

Select the correct statement about salmeterol: A. It is a long acting selective β2 agonist bronchodilator B. It is a bronchodilator with anti-inflammatory property C. It is a β blocker that can be safely given to asthmatics D. It is an antihistaminic with mast cell stabilizing property

Description : Select the correct statement about salmeterol: A. It is a long acting selective β2 agonist bronchodilator B. It is a bronchodilator with anti-inflammatory property C. It is a β blocker that can be safely given to asthmatics D. It is an antihistaminic with mast cell stabilizing property

Last Answer : A. It is a long acting selective β2 agonist bronchodilator

Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or SIRS. B. A cardiac index (CI) of 6 liters per minute per square meter of body surface, a pulmonary capillary wedge pressure of 15 mm. Hg, and a systemic vascular resistance index (SVRI) of 800 dynes-sec/(cm 5-m 2) is a hemodynamic profile consistent with septic shock. C. An increase in SvO 2 in septic patients may be explained by the finding of anatomic arteriovenous shunts. D. Results of human trials employing antimediator therapy, such as antiendotoxin antibodies, IL-1 receptor antagonist, and tumor necrosis factor (TNF) antibodies, have confirmed animal studies that demonstrate a significant im

Description : Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or ... animal studies that demonstrate a significant improvement in survival with the use of such agents.

Last Answer : Answer: AB DISCUSSION: Shock due to sepsis or SIRS frequently manifests as a hyperdynamic cardiovascular response, consisting of an elevated CI and a decreased SVR or SVRI. Occasionally, ... been encouraging thus far in human clinical trials, despite the promising results from many animal studies

Following potassium sparing diuretic is a mineralocorticoid receptor antagonist (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Description : Following potassium sparing diuretic is a mineralocorticoid receptor antagonist (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Last Answer : Ans: C

Which of the following medications represents the category proton (gastric acid) pump inhibitors? a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine-triphosphatase pump on the surface of the parietal cells. b) Sucralfate (Carafate) Sucralfate is a cytoprotective drug. c) Famotidine (Pepcid) Famotidine is a histamine-2 receptor antagonist. d) Metronidazole (Flagyl) Metronidazole is an antibiotic, specifically an amebicide.

Description : Which of the following medications represents the category proton (gastric acid) pump inhibitors? a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine ... antagonist. d) Metronidazole (Flagyl) Metronidazole is an antibiotic, specifically an amebicide.

Last Answer : a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine-triphosphatase pump on the surface of the parietal cells.

Choose the correct statement about sibutramine: A. It is an anorectic drug used to assist weight reduction B. It is an atypical antidepressant C. It is a 5-HT1D receptor antagonist D. Both A and C are correct

Description : Choose the correct statement about sibutramine: A. It is an anorectic drug used to assist weight reduction B. It is an atypical antidepressant C. It is a 5-HT1D receptor antagonist D. Both A and C are correct

Last Answer : A. It is an anorectic drug used to assist weight reduction

Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It is a synthetic atropine substitute used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms

he following anthelmintic acts as a cholinergic agonist in the nematodes and causes spastic paralysis of the worms: A. Piperazine B. Pyrantel pamoate C. Mebendazole D. Thiabendazole

Description : he following anthelmintic acts as a cholinergic agonist in the nematodes and causes spastic paralysis of the worms: A. Piperazine B. Pyrantel pamoate C. Mebendazole D. Thiabendazole

Last Answer : B. Pyrantel pamoate

The following category of drugs is not indicated in early/mild cases of Parkinson's disease: A. Central anticholinergic B. MAO-B inhibitor C. COMT inhibitor D. Nonergoline dopaminergic agonist

Description : The following category of drugs is not indicated in early/mild cases of Parkinson's disease: A. Central anticholinergic B. MAO-B inhibitor C. COMT inhibitor D. Nonergoline dopaminergic agonist

Last Answer : C. COMT inhibitor