How does the sequence of DNA affect the function of a protein?

How does the sequence of DNA affect the function of a protein?
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Answer :

The sequence of nucleotides in DNA molecule is equivalent and isclosely related to an amino acid sequence in the protein molecule.If for any reason the sequence of DNA nucleotides changes it willbe reflected in amino acid sequence in the protein. Moreover, thecorrect sequence of amino acid in the protein will form the correctthree-dimensional structure, or tertiary structure, that willconfer the biological activity to protein. If a wrong amino acid istranslated from a mutated gene in the DNA could change the spatialstructure of the protein and therefore modify or erase itsbiological function.
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Related questions

What Portion of DNA which carries the genetic code for the formation of a particular protein by specifying its amino acids sequence?

Description : What Portion of DNA which carries the genetic code for the formation of a particular protein by specifying its amino acids sequence?

Last Answer : Gene

The genetic code operates via (A) The protein moiety of DNA (B) The base sequences of DNA (C) The nucleotide sequence of mRNA (D) The base sequence of tRNA

Description : The genetic code operates via (A) The protein moiety of DNA (B) The base sequences of DNA (C) The nucleotide sequence of mRNA (D) The base sequence of tRNA

Last Answer : Answer : C

The genetic code operates through (A) The protein moiety of DNA (B) Cistrom of DNA (C) Nucleotide sequence of m RNA (D) The anticodons of tRNA

Description : The genetic code operates through (A) The protein moiety of DNA (B) Cistrom of DNA (C) Nucleotide sequence of m RNA (D) The anticodons of tRNA

Last Answer : Answer : C

Restriction endonucleases recognize and cut a certain sequence of (A) Single stranded DNA (B) Double stranded DNA (C) RNA (D) Protein

Description : Restriction endonucleases recognize and cut a certain sequence of (A) Single stranded DNA (B) Double stranded DNA (C) RNA (D) Protein

Last Answer : Answer : B

Termination of the synthesis of the RNA molecule is signaled by a sequence in the template strand of the DNA molecule, a signal that is recognized by a termination protein, the (A) Rho (ρ) factor (B) σ factor (C) δ factor (D) ε factor

Description : Termination of the synthesis of the RNA molecule is signaled by a sequence in the template strand of the DNA molecule, a signal that is recognized by a termination protein, the (A) Rho (ρ) factor (B) σ factor (C) δ factor (D) ε factor

Last Answer : Answer : A

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

In the regulation of genes: a. more than 90% of the base sequences in human DNA have not known function b. extrons are the part of the gene that code for amino acids found in the final proteins. c. introns usually begins with the nucleotide sequence GT d. all above

Description : In the regulation of genes: a. more than 90% of the base sequences in human DNA have not known function b. extrons are the part of the gene that code for amino acids found in the final proteins. c. introns usually begins with the nucleotide sequence GT d. all above

Last Answer : all above

Why would denaturing a protein affect its ability to function properly?

Description : Why would denaturing a protein affect its ability to function properly?

Last Answer : Need answer

The primary structure of a protein refers to the sequence of amino acids that are linked together in a long chain. Which of the following common items would best represent the primary structure of a protein?

Description : The primary structure of a protein refers to the sequence of amino acids that are linked together in a long chain. Which of the following common items would best represent the primary structure of a protein?

Last Answer : beads of different colors joined together on a piece of string

A synthetic RNA having the sequence of UUUUUU (Poly U) will give a protein having poly ______. (A) Alamine (B) Phenyl alanine (C) Glycine (D) Methionine

Description : A synthetic RNA having the sequence of UUUUUU (Poly U) will give a protein having poly ______. (A) Alamine (B) Phenyl alanine (C) Glycine (D) Methionine

Last Answer : Answer : B

Insertion of a base in a gene can cause (A) Change in reading frame (B) Garbled amino acid sequence in the encoded protein (C) Premature termination of translation (D) All of these

Description : Insertion of a base in a gene can cause (A) Change in reading frame (B) Garbled amino acid sequence in the encoded protein (C) Premature termination of translation (D) All of these

Last Answer : Answer : D

Amino acid sequence of the encoded protein is not changed in (A) Silent mutation (B) Acceptable mis-sense mutation (C) Both (A) and (B) (D) None of these

Description : Amino acid sequence of the encoded protein is not changed in (A) Silent mutation (B) Acceptable mis-sense mutation (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A

The half-life of a protein depends upon its (A) Signal sequence (B) N-terminus amino acid (C) C-terminus amino acid (D) Prosthetic group

Description : The half-life of a protein depends upon its (A) Signal sequence (B) N-terminus amino acid (C) C-terminus amino acid (D) Prosthetic group

Last Answer : Answer : B

In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core enzymes of RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Description : In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core ... RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Last Answer : Answer : C

Edman’s reaction can be used to (A) Determine the number of tyrosine residues in a protein (B) Determine the number of aromatic amino acid residues in a protein (C) Determine the amino acid sequence of a protein (D) Hydrolyse the peptide bonds in a protein

Description : Edman’s reaction can be used to (A) Determine the number of tyrosine residues in a protein (B) Determine the number of aromatic amino acid residues in a protein (C) Determine the amino acid sequence of a protein (D) Hydrolyse the peptide bonds in a protein

Last Answer : Answer : C

Amino acid sequence directs protein folding?

Description : Insulin possesses two polypeptide chains denoted A and B that are linked by disulfide bonds. Upon denaturation by reduction of the SH groups of insulin, followed by reoxidation, only 7% of the ... can these data be reconciled with the hypothesis that the amino acid sequence directs protein folding?

Last Answer : Insulin is synthesized as preproinsulin that is proteolytically processed in the β cells of the islets of Langerhans in the pancreas, to give proinsulin. After synthesis and folding, a section of the ... lacking the C peptide, lacks some of the information necessary to direct the folding process. 

Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Description : Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Last Answer : (b) tRNA

The correct sequence for the manufacture of molecules/organic compounds on the primitive earth is (a) NH3, nucleic acid, protein and carbohydrate (b) protein, carbohydrate, water and nucleic acid (c) NH3, protein, carbohydrate and nucleic acid (d) NH3, water, nucleic acid and protein.

Description : The correct sequence for the manufacture of molecules/organic compounds on the primitive earth is (a) NH3, nucleic acid, protein and carbohydrate (b) protein, carbohydrate, water and nucleic acid (c) NH3, protein, carbohydrate and nucleic acid (d) NH3, water, nucleic acid and protein.

Last Answer : (d) NH3, water, nucleic acid and protein.

.Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Description : .Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Last Answer : (c) mRNA

The primary structure of a protein refers to : (a) whether the protein is fibrous or globular (b) the amino acid sequence in the polypeptide chain (c) the orientation of the amino acid side chains in space (d) the presence or absence of an α-helix

Description : The primary structure of a protein refers to : (a) whether the protein is fibrous or globular (b) the amino acid sequence in the polypeptide chain (c) the orientation of the amino acid side chains in space (d) the presence or absence of an α-helix

Last Answer : the amino acid sequence in the polypeptide chain

Which of the following is the “quaternary structure” of proteins concerned with? (a) sequence of amino acids in the peptide chain (b) description of the way the peptide chains are arranged with respect to each other (c) location of the disulfide bridges in the peptide chain (d) conformation of the protein backbone

Description : Which of the following is the quaternary structure of proteins concerned with? (a) sequence of amino acids in the peptide chain (b) description of the way the peptide chains are arranged with ... (c) location of the disulfide bridges in the peptide chain (d) conformation of the protein backbone

Last Answer : description of the way the peptide chains are arranged with respect to each other

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequenceof a gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... sequenceof a gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

The rivosome binding site A- forms a sltem- loop structure in the RNA B- is located upstream of the promoter sequence C- is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The rivosome binding site A- forms a sltem- loop structure in the RNA B- is located upstream of the promoter sequence C- is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : is located immediately upstream of the start codon

The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

The _______ structure of a protein is the sequence of amino acids. a. primary b. secondary c. tertiary d. quaternary

Description : The _______ structure of a protein is the sequence of amino acids. a. primary b. secondary c. tertiary d. quaternary

Last Answer : a. primary

RNA molecules can be broken up into three classes-which type of RNA molecule is translated into a protein sequence?

Description : RNA molecules can be broken up into three classes-which type of RNA molecule is translated into a protein sequence?

Last Answer : Messenger RNA (mRNA). mRNAs are the RNA transcripts that contain protein coding sequences which are translated into protein.

Sequence of AAT GCT TAG GCA on template segment of DNA will be represented over the transcribed mRNA as

Description : Sequence of AAT GCT TAG GCA on template segment of DNA will be represented over the transcribed mRNA as

Last Answer : Sequence of AAT GCT TAG GCA on template segment of DNA will be represented over the transcribed mRNA as A. ... C. UUA CGA AUC CGU D. TTA CGA ATC CGT

Assetion: Insertion of recombinant DNA within the coding sequence of `beta-`galactosidase result n colourless colonies. Reason : Presence of insert re

Description : Assetion: Insertion of recombinant DNA within the coding sequence of `beta-`galactosidase result n colourless colonies. Reason : Presence of insert re

Last Answer : Assetion: Insertion of recombinant DNA within the coding sequence of `beta-`galactosidase result n ... D. If both assertion and reason are false

What is the mRNA sequence if the DNA sequence is GATCCT?

Description : What is the mRNA sequence if the DNA sequence is GATCCT?

Last Answer : Need answer

Why is a particular sequence of bases in a segment of DNA important to cells?

Description : Why is a particular sequence of bases in a segment of DNA important to cells?

Last Answer : Feel Free to Answer

What is the sequence of the bases on one DNA strand?

Description : What is the sequence of the bases on one DNA strand?

Last Answer : Feel Free to Answer

What is the change in DNA sequence that affects genetic information?

Description : What is the change in DNA sequence that affects genetic information?

Last Answer : Mutation

If the base sequence on a separated DNA strand is CGTAGG what will the base sequence on its complementary strand be?

Description : If the base sequence on a separated DNA strand is CGTAGG what will the base sequence on its complementary strand be?

Last Answer : What is the answer ?

What Describes a change in the sequence of DNA molecule?

Description : What Describes a change in the sequence of DNA molecule?

Last Answer : What is the answer ?

What do you sometimes call the special images showing an organism and sequence of DNA bases?

Description : What do you sometimes call the special images showing an organism and sequence of DNA bases?

Last Answer : Need answer

Which sequence of RNA bases with pair up with a strand of DNA bases that reads TACTGCA?

Description : Which sequence of RNA bases with pair up with a strand of DNA bases that reads TACTGCA?

Last Answer : color

Any change in the nucleotide sequence of dna is called what?

Description : Any change in the nucleotide sequence of dna is called what?

Last Answer : A change in the nucleotide sequence of DNA is called a mutation.Mutations take several forms:* substitution: one base is replaced by another* deletion: one or more nucleotides disappear from the ... likely to occur at a point during replication of DNA when the two strands are separated.

Anticodon sequence are seen in (A) tRNA and transcribed DNA strand (B) tRNA and complementary DNA strand (C) mRNA (D) mRNA and complementary DNA strand

Description : Anticodon sequence are seen in (A) tRNA and transcribed DNA strand (B) tRNA and complementary DNA strand (C) mRNA (D) mRNA and complementary DNA strand

Last Answer : Answer : A

Base sequence of DNA can be determined by (A) Maxam-Gilbert method (B) Sanger’s dideoxy method (C) Both (A) and (B) (D) None of these

Description : Base sequence of DNA can be determined by (A) Maxam-Gilbert method (B) Sanger’s dideoxy method (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

In sanger’s method of DNA sequence determination, DNA synthesis is stopped by using (A) 1′, 2′- Dideoxyribonucleoside triphosphates (B) 2′, 3′- Dideoxyribonucleoside triphosphates (C) 2′, 4′- Dideoxyribonucleoside triphosphates (D) 2′, 5′ - Dideoxyribonucleoside triphosphates

Description : In sanger’s method of DNA sequence determination, DNA synthesis is stopped by using (A) 1′, 2′- Dideoxyribonucleoside triphosphates (B) 2′, 3′- Dideoxyribonucleoside triphosphates (C) 2′, 4′- Dideoxyribonucleoside triphosphates (D) 2′, 5′ - Dideoxyribonucleoside triphosphates

Last Answer : Answer : B

A consensus sequence on DNA, called TATA box, is the site for attachment of (A) RNA-dependent DNA polymerase (B) DNA-dependent RNA polymerase (C) DNA-dependent DNA polymerase (D) DNA topoisomerase II

Description : A consensus sequence on DNA, called TATA box, is the site for attachment of (A) RNA-dependent DNA polymerase (B) DNA-dependent RNA polymerase (C) DNA-dependent DNA polymerase (D) DNA topoisomerase II

Last Answer : Answer : B

Repressor binds to DNA sequence and regulate the transcription. This sequence is called (A) Attenuator (B) Terminator (C) Anti terminator (D) Operator

Description : Repressor binds to DNA sequence and regulate the transcription. This sequence is called (A) Attenuator (B) Terminator (C) Anti terminator (D) Operator

Last Answer : Answer : D

In the following partial sequence of mRNA, a mutation of the template DNA results in a change in codon 91 to UAA. The type of mutation is 88 89 90 91 92 93 94 GUC GAC CAG UAG GGC UAA CCG (A) Missene (B) Silent (C) Nonsense (D) Frame shit

Description : In the following partial sequence of mRNA, a mutation of the template DNA results in a change in codon 91 to UAA. The type of mutation is 88 89 90 91 92 93 94 GUC GAC CAG UAG GGC UAA CCG (A) Missene (B) Silent (C) Nonsense (D) Frame shit

Last Answer : Answer : B

Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme activity (B) Glucose-6-P Dehydroglucose deficiency leads to disfuction of many tissues (C) G-6-p Dehydroglucose deficiency is due to a single deletion of a large sequence of DNA in the G-6-PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

Last Answer : Answer : A

The process of synthesizing multiple copies of a particular DNA sequence

Description : The process of synthesizing multiple copies of a particular DNA sequence

Last Answer : Ans. Gene cloning

A DNA sequence that codes for a specific polypeptide

Description : A DNA sequence that codes for a specific polypeptide

Last Answer : Ans. Cistron