What should be the properties of powder to be filled in hard gelatine capsule?

What should be the properties of powder to be filled in hard gelatine capsule?
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1 Answer

Answer :

Properties of powder:

Flow property of powders depends upon followings:

1. Particle size.: Uniform

2. Particle shape.: Spherical

3. Density: same density

4. Surface texture: smooth

5. Angle of repose.

• Maximum angle which is formed between the surface of a pile of powder and horizontal surface is called the “angle of repose”.

• This is determined for flow properties of powder.

• It is Tan Ø = 2h/D or h/r.

• The powder flow smoothly, if angle of repose is 250.

• The powder does not flow smoothly, if angle of repose is more than 500. 

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