Define capsule. Differentiate between hard and soft gelatine capsules.

Define capsule. Differentiate between hard and soft gelatine capsules.
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1 Answer

Answer :

Capsule:  Capsules are a solid unit dosage form in which the drug substances are enclosed in a water soluble shell or an envelope. 


Differentiate:

Sr.No
Hard gelatin capsules 
Soft gelatin capsules 
1 The hard gelatin capsule shell consists of two parts: Body and cap
The soft gelatin capsule shell becomes a single unit. 
2 They are cylindrical in shape.
They are available in round, oval and tube-like shapes.
3 The contents usually consist of medicaments in the form of powder, beads or granules.
The contents usually consist of liquids or semisolids.
4 These are prepared from gelatin, titanium dioxide, colouring agent and plasticizer.
These are prepared from gelatin, more amount of plasticizer (sorbitol or glycerin) and preservative. 
5 Filling and sealing takes place in different steps. 
Filling and sealing are done in a combined operation of machines
6 Shell is perfectly dry.
Shell is not perfectly dry
7 These capsules can be adulterated 
These capsules cannot be adulterated 
8 Eg. Becosules capsules 
Eg. Pudin Hara
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