Discuss the excipients used in filling of hard gelatin capsule.

Discuss the excipients used in filling of hard gelatin capsule.
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1 Answer

Answer :

i. Diluents:

To increase bulk, e.g. lactose, sorbitol, starch etc.

ii. Absorbents:

Eutectic or hygroscopic drug need absorbent for, e.g. oxides and carbonates of magnesium and calcium.

iii. Glidants:

To ensure a regular flow of powder, e.g. talc and magnesium stearate.

iv. Antidusting agents:

During filling of capsule in automatic filling machine a lot of dust comes out to avoid this Antidusting agent added e.g. inert oils.
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