Description : Atropine does not antagonise the following feature of anticholinesterase poisoning: A. Hypotension B. Central excitation C. Muscle paralysis D. Bronchoconstriction
Last Answer : C. Muscle paralysis
Description : The following drug/drugs should not be used to treat tricyclic antidepressant drug poisoning: A. Quinidine B. Digoxin C. Atropine D. All of the above
Last Answer : D. All of the above
Description : The following is not a feature of thiazide diuretics used as antihypertensive: A. They do not cause symptomatic postural hypotension B. The dose has to be titrated over a wide range ... has developed D. They decrease renal calcium excretion which may improve calcium balance in elderly patients
Last Answer : B. The dose has to be titrated over a wide range according to the response
Description : Select the muscle relaxant that is used to control spasticity associated with upper motor neurone paralysis: A. Vecuronium B. Succinylcholine C. Chlorzoxazone D. Baclofen
Last Answer : D. Baclofen
Description : Succinylcholine is the preferred muscle relaxant for tracheal intubation because: A. It produces rapid and complete paralysis of respiratory muscles with quick recovery B. It does not alter heart rate or ... C. It does not cause histamine release D. It does not produce postoperative muscle soreness
Last Answer : A. It produces rapid and complete paralysis of respiratory muscles with quick recovery
Description : Atropine does not exert relaxant/antispasmodic effect on the following muscle: A. Intestinal B. Ureteric C. Bronchial D. Laryngeal
Last Answer : D. Laryngeal
Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation
Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms
Description : The organ most sensitive to actions of atropine is: A. Gastric glands B. Salivary glands C. Urinary bladder muscle D. Heart
Last Answer : B. Salivary glands
Description : Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) ... Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
Last Answer : Ans: B
Description : Children are more susceptible than adults to the following action of atropine: A. Tachycardia producing B. Cycloplegic C. Gastric antisecretory D. Central excitant and hyperthermic
Last Answer : D. Central excitant and hyperthermic
Description : The following can be used to antagonise the action of heparin in case of overdose: A. Heparan sulfate B. Dextran sulfate C. Protamine sulfate D. Ancrod
Last Answer : C. Protamine sulfate
Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other's side effects B. Nitrates primarily ... primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca
Last Answer : B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load
Description : The following statement is true about endogenous opioid peptides: A. They activate only μ opioid recepors B. They do not occur in peripheral tissues C. They mediate stress induced analgesia D. Naloxone fails to antagonise their actio
Last Answer : C. They mediate stress induced analgesia
Description : Lower dose of naloxone is required to: A. Antagonise the actions of nalorphine B. Antagonise the actions of pentazocine C. Precipitate withdrawal in mildly morphine dependent subjects D. Precipitate withdrawal in highly morphine dependent subjects
Last Answer : D. Precipitate withdrawal in highly morphine dependent subjects
Description : A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse ... likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT
Last Answer : C. Anticholinesterase
Description : A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse ... likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT)
Description : Select the correct statement abut donepezil: A. It is a topical carbonic anhydrase inhibitor used in glaucoma B. It is a catechol-'O'-methyl transferase inhibitor used as adjuvant in ... affords symptomatic improvement in Alzheimer's disease D. It is a synthetic cannabinoid with antiemetic property
Last Answer : C. It is a cerebroselective anticholinesterase that affords symptomatic improvement in Alzheimer's diseas
Description : Hepatotoxicity has markedly restricted use of the following cerebroselective anticholinesterase in Alzheimer's disease: A. Rivastigmine B. Tacrine C. Galantamine D. Donepezil
Last Answer : B. Tacrine
Description : Which of the following is a relatively cerebroselective anticholinesterase found to afford symptomatic improvement in Alzheimer's disease: A. Donepezil B. Gemfibrozil C. Pyridostigmine D. Pyritinol
Last Answer : A. Donepezil
Description : The following kinin action is mediated primarily by the kinin B1 receptor: A. Intestinal contraction B. Bronchoconstriction C. EDRF release and vasodilatation D. Production of Interleukin, TNFα and other inflammatory mediators
Last Answer : . Production of Interleukin, TNFα and other inflammatory mediators
Description : Actions of bradykinin include the following except: A. Fall in blood pressure B. Cardiac depression C. Increase in capillary permeability D. Bronchoconstriction
Last Answer : B. Cardiac depression
Description : Choose the correct statement about cysteinyl leukotrienes (LT-C4/D4): A. They produce long lasting bronchoconstriction B. They produce sustained rise in blood pressure C. They are responsible ... and sequestrating neutrophils at the site of inflammation D. Their production is inhibited by rofecoxib
Last Answer : A. They produce long lasting bronchoconstriction
Description : The effects of topically applied anticholinesterase on the eye include: a. conjunctival hyperaemia b. raised intraocular pressure c. ciliary muscle contraction d. sphincter pupillae muscle relaxation e. retraction of the upper lids
Last Answer : ciliary muscle contraction
Description : Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) ... organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.
Last Answer : Answer: C DISCUSSION: Cytokines are soluble peptide molecules that are synthesized and secreted by a number of cell types in response to injury, inflammation, and infection. Cytokines, which ... is thought to play a central role in the stress response, particularly in response to endotoxemia
Description : The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla
Last Answer : B. Direct action on vascular smooth muscle causing vasodilatation
Description : The greatest threat from morphine poisoning is (a) Renal shutdown (b) Paralysis of spinal cord (c) Respiratory depression (d) Cardiovascular collapse (e) None of the above
Last Answer : Ans: C
Description : Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline
Last Answer : A. Atropine sulfate
Description : The most important complication of streptokinase therapy is: A. Hypotension B. Bleeding C. Fever D. Anaphylaxis
Last Answer : B. Bleeding
Description : n the treatment of hypertension the beta adrenergic blockers have the following advantage: A. They have minimal effect on work capacity, sleep quality and libido B. They do not cause ... high ceiling antihypertensive efficacy D. They can be used in combination with any other antihypertensive drug
Last Answer : B. They do not cause postural hypotension
Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : The limitations of quinidine in the treatment of cardiac arrhythmias include the following except: A. It has narrow spectrum antiarrhythmic activity B. It is not tolerated by many patients C. It can precipitate myocardial decompensation D. It can cause marked hypotension
Last Answer : A. It has narrow spectrum antiarrhythmic activity
Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action
Last Answer : C. It is less liable to cause abrupt first dose hypotension
Description : Which of the following adverse effects of neuroleptic drugs is positively correlated to the antipsychotic potency of the different compounds: A. Sedation B. Extrapyramidal motor disturbances C. Postural hypotension D. Lowering of seizure threshold
Last Answer : B. Extrapyramidal motor disturbances
Description : Actions of chlorpromazine include the following except: A. Indifference to external stimuli B. Postural hypotension C. Hypoprolactinemia D. Hypothermia in cold surroundings
Last Answer : C. Hypoprolactinemia
Description : Which of the following adverse effects of levodopa has a delayed onset and increases in severity with continued therapy: A. Nausea and vomiting B. Postural hypotension C. Cardiac arrhythmia D. Abnormal movements
Last Answer : D. Abnormal movements
Description : The following factor is not involved in the causation of hypotension due to spinal anaesthesia: A. Histamine release B. Reduced sympathetic vasoconstrictor tone C. Decreased venous return from the lower limbs D. Bradycardia
Last Answer : A. Histamine release
Description : While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP: A. Noradrenaline B. Isoprenaline C. Mephentermine D. Isoxsuprine
Last Answer : C. Mephentermine
Description : While undergoing a surgical procedure a patient develops hypotension. Which drug can be injected intramuscularly to raise his BP: A. Noradrenaline B. Isoprenaline C. Mephentermine D. Isoxsuprine
Description : The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation
Last Answer : B. Bradycardia
Description : he following anthelmintic acts as a cholinergic agonist in the nematodes and causes spastic paralysis of the worms: A. Piperazine B. Pyrantel pamoate C. Mebendazole D. Thiabendazole
Last Answer : B. Pyrantel pamoate
Description : The most probable mechanism of action of mebendazole is: A. Depolarization of membrane and spastic paralysis of the worm B. Hyperpolarization of membrane and flaccid paralysis of the worm C. Loss of ... inhibition of glucose uptake in the worm D. Tegument damage and leakage of contents of the worm
Last Answer : C. Loss of intracellular microtubules and inhibition of glucose uptake in the worm
Description : Neostigmine reverses the following actions of d-tubocurarine except: A. Motor weakness B. Ganglionic blockade C. Histamine release D. Respiratory paralysis
Last Answer : C. Histamine release
Description : Succinylcholine produces spastic paralysis in: A. Rabbits B. Frogs C. Birds D. Patients with atypical pseudocholinesterase
Last Answer : C. Birds
Description : A small amount of atropine is added to the diphenoxylate tablet/syrup to: A. Suppress associated vomiting of gastroenteritis B. Augment the antimotility action of diphenoxylate C. Block side effects of diphenoxylate D. Discourage overdose and abuse of diphenoxylate
Last Answer : D. Discourage overdose and abuse of diphenoxylate
Description : The progastrokinetic action of the following drug(s) is attenuated by atropine: A. Domperidone B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C’
Last Answer : D. Both ‘B’ and ‘C