Description : Glycopyrrolate is the preferred antimuscarinic drug for use before and during surgery because: A. It is potent and fast acting B. It has no central action C. It has antisecretory and vagolytic actions D. All of the above
Last Answer : B. It has no central action
Description : Glycopyrrolate is the preferred antimuscannic drug for use before and during surgery because (a) It is potent and fast acting (b) It has no central action (c) It has antisecretory and vagolytic actions (d) All of the above
Last Answer : Ans: D
Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine
Last Answer : C. They are devoid of CNS and ocular effects
Description : Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects
Last Answer : D. It produces prominent extrapyramidal side effect
Description : Che following is true of desmopressin except: A. It is nonselective V1 and V2 receptor agonist B. It is more potent and longer acting than arginine vasopressin (AVP) C. It is preferred over AVP for treatment of diabetes insipidus D. It can be administered orally
Last Answer : A. It is nonselective V1 and V2 receptor agonist
Description : Desmopressin is preferred over arginine vasopressin in the treatment of diabetes insipidus for the following reasons except: A. It is a more potent antidiuretic B. It is a selective vasopressin V1 receptor agonist C. It has little vasoconstrictor activity D. It is longer acting
Last Answer : B. It is a selective vasopressin V1 receptor agonist
Description : Children are more susceptible than adults to the following action of atropine: A. Tachycardia producing B. Cycloplegic C. Gastric antisecretory D. Central excitant and hyperthermic
Last Answer : D. Central excitant and hyperthermic
Description : The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting
Last Answer : A. They have potent antiovulatory action of their own
Description : Use of glycopyrrolate in preanaesthetic medication serves the following purposes except: A. Prevents respiratory secretions during anaesthesia B. Guards against reflex vagal bradycardia during ... Produces amnesia for perioperative events D. Reduces the probability of occurrence of laryngospasm
Last Answer : C. Produces amnesia for perioperative events
Description : Which of the following anticholinergic drugs is primarily used in preanaesthetic medication and during surgery: A. Glycopyrrolate B. Pipenzolate methyl bromide C. Isopropamide D. Dicyclomine
Last Answer : A. Glycopyrrolate
Description : Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect
Last Answer : C. It does not have antiandrogenic action
Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case
Last Answer : D. They are the preferred drugs in advanced cases
Description : For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamethasone/dexamethasone because: A. They do not cause Na+ and water retention B. They are more potent C. They can be administered intravenously D. They inhibit brain tumours
Last Answer : A. They do not cause Na+ and water retention
Description : Metformin is preferred over phenformin because: A. It is more potent B. It is less liable to cause lactic acidosis C. It does not interfere with vitamin B12 absorption D. It is not contraindicated in patients with kidney disease
Last Answer : B. It is less liable to cause lactic acidosis
Description : The following class of gastric antisecretory drug also reduce gastric motility and have primary effect on juice volume, with less marked effect on acid and pepsin A. Histamine H2 blockers B. Anticholinergics C. Proton pump inhibitors D. Prostaglandins
Last Answer : B. Anticholinergics
Description : Among all cardiac glycosides, digoxin is the most commonly used, because: A. It is the most potent and fastest acting glycoside B. It has the highest and most consistent oral ... so that dose adjustments are possible every 2-3 days and toxicity abates rather rapidly after discontinuatio
Last Answer : D. It has intermediate plasma half life so that dose adjustments are possible every 2-3 days and toxicity abates rather rapidly after discontinuatio
Description : Tolerance is generally not acquired to: A. Antisecretory action of atropine B. Sedative action of chlorpromazine C. Emetic action of levodopa D. Vasodilator action of nitrates
Last Answer : A. Antisecretory action of atropine
Description : The 19-Norprogestins differ from progesterone derivatives in that they: A. Have potent antiovulatory activity B. Have no additional androgenic activity C. Have no additional estrogenic activity D. Are preferred for use in endometriosi
Last Answer : A. Have potent antiovulatory activity
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits
Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low
Description : The following is a very potent and short acting benzodiazepine whose use as hypnotic has been noted to cause psychiatric disturbances in some cases: A. Flurazepam B. Nitrazepam C. Temazepam D. Triazolam
Last Answer : D. Triazolam
Description : Dexamethasone differs from prednisolone in that it is: A. Longer acting B. More potent C. More selective D. All of the above
Last Answer : D. All of the above
Description : The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they: A. Are more potent B. Are longer acting C. Do not lower blood sugar in nondiabetic subjects D. Are less prone to cause hypoglycaemic reaction
Last Answer : A. Are more potent
Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity
Last Answer : A. Exerts depressant effects on the CNS at relatively low doses
Description : Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin
Last Answer : B. Zolpidem
Description : Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects
Last Answer : D. It is unlikely to produce anti-androgenic side effects
Description : The following drug has potent antiandrogenic and weak progestational activity: A. Ethylestrenol B. Clomiphene citrate C. Cyproterone acetate D. Magestrol acetate
Last Answer : D. Magestrol acetate
Description : Out of two anticholinesterases, drug X' is a tertiary amine while drug Y' is a quarternary ammonium compound. Then: A. Drug X' is likely to be more potent than Y' B. Drug X' will be more ... a miotic C. Drug Y' will be completely metabolized in the body D. Drug Y' will produce CNS effects
Last Answer : B. Drug ‘X’ will be more suitable to be used as a miotic
Description : Which of the following anticholinergic drugs is primarily used in preanaesthetic medication and during surgery (a) Glycopyrrolate (b) Pipenzolate methyl bromide (c) Isopropamide (d) Dicyclomine
Last Answer : Ans: A
Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action
Last Answer : B. They produce many side effects
Description : Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action
Last Answer : B. Its hypnotic action shows little fading on repeated nightly use
Description : Features of atorvastatin include the following: A. Dose to dose most potent HMG-CoA reductase inhibitor B. Higher ceiling of LDL-cholesterol lowering action than lovastatin C. Antioxidant property D. All of the above
Description : Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene
Last Answer : B. It can be used to treat lithium induced diabetes insipidus
Description : Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action
Last Answer : D. Lisinopri
Description : Compared to pork/beef insulins, the human insulins: A. Are more potent B. Have a faster kinetics of absorption and elimination C. Have longer biological action half life D. Penetrate blood-brain barrier more efficiently
Last Answer : B. Have a faster kinetics of absorption and elimination
Description : riiodothyronine differs from thyroxine in that: A. It is more avidly bound to plasma proteins B. It has a shorter plasma half life C. It is less potent D. It has a longer latency of action
Last Answer : B. It has a shorter plasma half life
Description : 17.2 Triiodothyronine differs from thyroxine in that: A. It is more avidly bound to plasma proteins B. It has a shorter plasma half life C. It is less potent D. It has a longer latency of action (
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is: A. Highly potent B. Highly efficacious C. Highly toxic D. Highly selective
Last Answer : D. Highly selective
Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH
Last Answer : A. They do not cross the blood-brain barrier
Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Low concentration of bupivacaine is preferred for spinal / epidural obstetric analgesia because: A. It has a longer duration of action B. It can produce sensory blockade without paralysing abdominal muscles C. ... in maternal tissues so that less reaches the foetus D. All of the above are correct
Last Answer : D. All of the above are correct
Description : Oxytocin is preferred over ergometrine for augmenting labour because: A. It has brief and titratable action B. It is less likely to cause foetal anoxia C. It is less likely to impede foetal descent D. All of the above
Description : Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked ... mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure
Last Answer : C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms
Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors
Last Answer : B. It is longer acting