Metformin is preferred over phenformin because: A. It is more potent B. It is less liable to cause lactic acidosis C. It does not interfere with vitamin B12 absorption D. It is not contraindicated in patients with kidney disease

Metformin is preferred over phenformin because:
A. It is more potent
B. It is less liable to cause lactic acidosis
C. It does not interfere with vitamin B12
absorption
D. It is not contraindicated in patients with
kidney disease
by

1 Answer

Answer :

B. It is less liable to cause lactic acidosis
by

Related questions

___________ drug can cause lactic acidosis. a) Metformin b) Pioglitazone c) Repaglinide d) Glibenclamide

Description : ___________ drug can cause lactic acidosis. a) Metformin b) Pioglitazone c) Repaglinide d) Glibenclamide

Last Answer : a) Metformin  

Morphine is contraindicated in head injury because: A. It does not relieve the pain of head injury B. It can raise intracranial tension C. It can cause constipation D. It is liable to cause addiction

Description : Morphine is contraindicated in head injury because: A. It does not relieve the pain of head injury B. It can raise intracranial tension C. It can cause constipation D. It is liable to cause addiction

Last Answer : B. It can raise intracranial tension

What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition

For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamethasone/dexamethasone because: A. They do not cause Na+ and water retention B. They are more potent C. They can be administered intravenously D. They inhibit brain tumours

Description : For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamethasone/dexamethasone because: A. They do not cause Na+ and water retention B. They are more potent C. They can be administered intravenously D. They inhibit brain tumours

Last Answer : A. They do not cause Na+ and water retention

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days C. Their dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

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Last Answer : A. They interfere with an early step in the synthesis of clotting factors

The major limitation of the thiazolidinediones in the treatment of type 2 diabetes mellitus is: A. Frequent hypoglycaemic episodes B. Hyperinsulinemia C. Lactic acidosis D. Low hypoglycaemic efficacy in moderate to severe cases

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Last Answer : D. Low hypoglycaemic efficacy in moderate to severe cases

The percentage of patients over the age of 70 admitted to the hospital with delirium is about a) 25%. About 25% of patients over the age of 70 admitted to the hospital have delirium. The cause is often reversible and treatable (as in drug toxicity, vitamin B12 deficiency or thyroid disease) or chronic and irreversible. Depression may produce impairment of attention and memory.

Description : The percentage of patients over the age of 70 admitted to the hospital with delirium is about a) 25%. About 25% of patients over the age of 70 admitted to the hospital have delirium. The cause is ... delirium. d) 50%. About 25% of patients over the age of 70 admitted to the hospital have delirium.

Last Answer : a) 25%. About 25% of patients over the age of 70 admitted to the hospital have delirium. The cause is often reversible and treatable (as in drug toxicity, vitamin B12 deficiency or thyroid disease) or chronic and irreversible. Depression may produce impairment of attention and memory.

Timolol eye drops are preferred over pilocarpine eye drops by glaucoma patients because: A. Timolol is more effective than pilocarpine B. Timolol acts by enhancing uveo-scleral outflow C. Timolol produces less ocular side effects D. There are no contraindications to timolol

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Last Answer : C. Timolol produces less ocular side effects

The following is true of selegiline: A. It does not exert antiparkinsonian action unless combined with levodopa B. It overcomes the ‘on-off ’ effect in levodopa treated advanced parkinsonian patients C. It retards the progression of Parkinson's disease D. At doses used in parkinsonism it does not interfere with peripheral metabolism of dietary amines

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Last Answer : . At doses used in parkinsonism it does not interfere with peripheral metabolism of dietary amines

The following factor(s) is/are required for the absorption of dietary vitamin B12: A. Gastric acid B. Gastric intrinsic factor C. Transcobalamine D. Both ‘A’ and ‘B’

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Last Answer : D. Both ‘A’ and ‘B

Morphine is contraindicated in head injury because (a) It does not relieve the pain of head injury (b) It can raise intracranial tension (c) It can cause constipation (d) It is liable to cause addiction

Description : Morphine is contraindicated in head injury because (a) It does not relieve the pain of head injury (b) It can raise intracranial tension (c) It can cause constipation (d) It is liable to cause addiction

Last Answer : Ans: B

Glycopyrrolate is the preferred antimuscarinic drug for use before and during surgery because: A. It is potent and fast acting B. It has no central action C. It has antisecretory and vagolytic actions D. All of the above

Description : Glycopyrrolate is the preferred antimuscarinic drug for use before and during surgery because: A. It is potent and fast acting B. It has no central action C. It has antisecretory and vagolytic actions D. All of the above

Last Answer : B. It has no central action

Glycopyrrolate is the preferred antimuscarinic drug for use before and during surgery because: A. It is potent and fast acting B. It has no central action C. It has antisecretory and vagolytic actions D. All of the above

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Last Answer : D. All of the above

Paracetamol has the following advantage(s) over NSAIDs: A. It is the first choice analgesic for majority of osteoarthritis patients B. It can be given safely to all age groups from infants to elderly C. It is not contraindicated in pregnant or breast feeding women D. All of the above

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Last Answer : D. All of the above

In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected

Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected

Last Answer : D. Disposition of atenolol is not significantly affected

In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected

Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected

Last Answer : D. Disposition of atenolol is not significantly affected

he following is true of desmopressin except: A. It is nonselective V1 and V2 receptor agonist B. It is more potent and longer acting than arginine vasopressin (AVP) C. It is preferred over AVP for treatment of diabetes insipidus D. It can be administered orally

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Last Answer : A. It is nonselective V1 and V2 receptor agonist

Stimulant purgatives are contraindicated in the following: A. Bed ridden patients B. Before abdominal radiography C. Spastic constipation D. Atonic constipation

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Last Answer : C. Spastic constipation

As an antacid, sodium bicarbonate has the following disadvantages except: A. It causes acid rebound B. In ulcer patients, it increases risk of perforation C. It has low acid neutralizing capacity D. It is contraindicated in hypertensives

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Last Answer : C. It has low acid neutralizing capacity

Heparin is contraindicated in patients suffering from the following diseases except: A. Pulmonary tuberculosis B. Bleeding due to defibrination syndrome C. Subacute bacterial endoc

Description : Heparin is contraindicated in patients suffering from the following diseases except: A. Pulmonary tuberculosis B. Bleeding due to defibrination syndrome C. Subacute bacterial endoc

Last Answer : B. Bleeding due to defibrination syndrome

The following is true of mannitol except: A. It inhibits solute reabsorption in the thick ascending limb of loop of Henle B. It is contraindicated in patients with increased intracranial tension C. It is contraindicated in acute left ventricular failure D. It is not used to treat cardiac or hepatic or renal edema

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Last Answer : B. It is contraindicated in patients with increased intracranial tension

Digoxin is contraindicated in: A. Angina pectoris patients B. Ventricular tachycardia C. Hypertensive patients D. Complete heart-block

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Last Answer : B. Ventricular tachycardia

Choose the correct statement about moclobemide: A. It is a reversible inhibitor of MAO-A with short duration of action B. Patients taking it need to be cautioned not to consume tyramine rich food C. It is contraindicated in elderly patients D. It produces anticholinergic side effect

Description : Choose the correct statement about moclobemide: A. It is a reversible inhibitor of MAO-A with short duration of action B. Patients taking it need to be cautioned not to consume tyramine rich food C. It is contraindicated in elderly patients D. It produces anticholinergic side effect

Last Answer : A. It is a reversible inhibitor of MAO-A with short duration of action

In patients of congestive heart failure, β-adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct

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Last Answer : D. Both B and C are correct

In patients of congestive heart failure, β -adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct

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Last Answer : D. Both B and C are correct

The 19-Norprogestins differ from progesterone derivatives in that they: A. Have potent antiovulatory activity B. Have no additional androgenic activity C. Have no additional estrogenic activity D. Are preferred for use in endometriosi

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Last Answer : A. Have potent antiovulatory activity

Choose the correct statement about methenamine (hexamine): A. It acts by getting converted to mandelic acid in the urinary tract B. It releases formaldehyde in acidic urine which inturn kills bacteria C. It is highly effective in acute urinary tract infections D. It is the preferred urinary antiseptic in patients with liver disease

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Last Answer : B. It releases formaldehyde in acidic urine which inturn kills bacteria

Oxytocin is preferred over ergometrine for augmenting labour because: A. It has brief and titratable action B. It is less likely to cause foetal anoxia C. It is less likely to impede foetal descent D. All of the above

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Last Answer : D. All of the above

Indicate the disease in which penicillin G continues to be used as first line treatment in all cases (unless contraindicated), because the causative organism has not developed resistance so far: A. Gonorrhoea B. Syphilis C. Staphylococcal abscess D. Haemophillus influenzae meningiti

Description : Indicate the disease in which penicillin G continues to be used as first line treatment in all cases (unless contraindicated), because the causative organism has not developed resistance so far: A. Gonorrhoea B. Syphilis C. Staphylococcal abscess D. Haemophillus influenzae meningiti

Last Answer : B. Syphilis

Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

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Last Answer : D. Lisinopri

Compared to ****/beef insulins, the human insulins: A. Are more potent B. Have a faster kinetics of absorption and elimination C. Have longer biological action half life D. Penetrate blood-brain barrier more efficiently

Description : Compared to pork/beef insulins, the human insulins: A. Are more potent B. Have a faster kinetics of absorption and elimination C. Have longer biological action half life D. Penetrate blood-brain barrier more efficiently

Last Answer : B. Have a faster kinetics of absorption and elimination

Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

The monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance

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Last Answer : B. They cause less hypoglycaemic reactions

he monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance

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Last Answer : B. They cause less hypoglycaemic reactions

Adrenergic β1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Description : Adrenergic β1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Last Answer : C. Withdrawal is less likely to exacerbate angina pectoris

Adrenergic β 1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Description : Adrenergic β 1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Last Answer : C. Withdrawal is less likely to exacerbate angina pectoris

The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they: A. Are more potent B. Are longer acting C. Do not lower blood sugar in nondiabetic subjects D. Are less prone to cause hypoglycaemic reaction

Description : The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they: A. Are more potent B. Are longer acting C. Do not lower blood sugar in nondiabetic subjects D. Are less prone to cause hypoglycaemic reaction

Last Answer : A. Are more potent

A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Description : A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Last Answer : Answers-1 The aetiology of gout can broadly be divided into cases where there is underexcretion of urate via the kidney (90%) or endogenous overproduction of uric acid (10%) although in practical ... diuretic use. Excessive dietary intake of purines is unlikely to be the main cause in this case.

Decrease in absorption of which of the following vitamins in the geriatric patient results in pernicious anemia? a) B12 Vitamin B12 requires the intrinsic factor secreted by the gastric mucosa for absorption. b) C Lack of vitamin C may cause development of signs and symptoms of scurvy. c) D Vitamin D deficiency results in an inability to absorb calcium. d) B6 Vitamin B6 affects neuromuscular function.

Description : Decrease in absorption of which of the following vitamins in the geriatric patient results in pernicious anemia? a) B12 Vitamin B12 requires the intrinsic factor secreted by the gastric mucosa for ... results in an inability to absorb calcium. d) B6 Vitamin B6 affects neuromuscular function.

Last Answer : a) B12 Vitamin B12 requires the intrinsic factor secreted by the gastric mucosa for absorption.

For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamenthasone/dexamethasone because (a) They do not cause Na+ and water retention (b) They are more potent (c) They can be administered intravenously (d) They inhibit brain tumours

Description : For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamenthasone/dexamethasone because (a) They do not cause Na+ and water retention (b) They are more potent (c) They can be administered intravenously (d) They inhibit brain tumours

Last Answer : Ans: A

Ergometrine is contraindicated in the following conditions except: A. Multiparity B. Toxaemia of pregnancy C. Pelvic sepsis D. Peripheral vascular disease

Description : Ergometrine is contraindicated in the following conditions except: A. Multiparity B. Toxaemia of pregnancy C. Pelvic sepsis D. Peripheral vascular disease

Last Answer : A. Multiparity

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while blood picture and haemoglobin level were improved. What could be the most likely explanation: A. Folic acid was not adequately absorbed resulting in partial response B. Folate therapy has precipitated vitamin B12 deficiency in the neural tissue C. Folate therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Description : A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while ... therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Last Answer : D. Patient has folate reductase abnormality in the nervous system

Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Description : Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Last Answer : C. Phenytoin therapy

A 60-year-old patient presented with anorexia, weakness, paresthesia and mental changes. His tongue was red, tendon reflexes were diminished, haemoglobin was 6 g% with large red cells and neutrophils had hypersegmented nuclei. Endoscopy revealed atrophic gastritis. Deficiency of which factor is likely to be responsible for his condition: A. Folic acid B. Vitamin B12 C. Pyridoxine D. Riboflavin

Description : A 60-year-old patient presented with anorexia, weakness, paresthesia and mental changes. His tongue was red, tendon reflexes were diminished, haemoglobin was 6 g% with large red cells and neutrophils had ... be responsible for his condition: A. Folic acid B. Vitamin B12 C. Pyridoxine D. Riboflavin

Last Answer : B. Vitamin B12

The metabolic reaction requiring vitamin B12 but not folate is: A. Conversion of malonic acid to succinic acid B. Conversion of homocysteine to methionine C. Conversion of serine to glycine D. Thymidylate synthesis

Description : The metabolic reaction requiring vitamin B12 but not folate is: A. Conversion of malonic acid to succinic acid B. Conversion of homocysteine to methionine C. Conversion of serine to glycine D. Thymidylate synthesis

Last Answer : A. Conversion of malonic acid to succinic acid

Megaloblastic anaemia occurs in: A. Vitamin B12 but not folic acid deficiency B. Folic acid but not Vitamin B12 deficiency C. Either Vitamin B12 or folic acid deficiency D. Only combined Vitamin B12 + folic acid deficiency

Description : Megaloblastic anaemia occurs in: A. Vitamin B12 but not folic acid deficiency B. Folic acid but not Vitamin B12 deficiency C. Either Vitamin B12 or folic acid deficiency D. Only combined Vitamin B12 + folic acid deficiency

Last Answer : C. Either Vitamin B12 or folic acid deficiency

The vitamin that is regarded to be a hormone is: A. Vitamin D B. Vitamin C C. Vitamin B12 D. Vitamin A

Description : The vitamin that is regarded to be a hormone is: A. Vitamin D B. Vitamin C C. Vitamin B12 D. Vitamin A

Last Answer : A. Vitamin D