Description : Histamine exerts the following actions except: A. Dilatation of large blood vessels B. Dilatation of small blood vessels C. Stimulation of isolated guineapig heart D. Itching
Last Answer : A. Dilatation of large blood vessels
Description : Stimulation of the beta receptors give rise to: a. tachycardia b. increased myocardial contraction c. vasoconstriction of visceral vessels d. pupil dilatation
Last Answer : increased myocardial contraction
Description : Depolarizing neuromuscular blockers differ from competitive blockers in the following attributes except: A. They induce contraction of isolated frog rectus abdominis muscle B. Ether anaesthesia ... produces well sustained contraction D. Neostigmine does not reverse block produced by them
Last Answer : B. Ether anaesthesia intensifies block produced by them
Description : Select the action of vasopressin exerted through the V1 subtype receptors: A. Release of coagulation factor VIII and von Willebrands factor from vascular endothelium B. Increased peristalsis of gut C. Dilatation of blood vessels D. Increased water permeability of renal collecting ducts
Last Answer : B. Increased peristalsis of gut
Description : Thyrotropin exerts the following actions on the thyroid gland except: A. Increases vascularity B. Inhibits proteolysis of thyroglobulin C. Induces hyperplasia and hypertrophy D. Promotes iodide trappin
Last Answer : B. Inhibits proteolysis of thyroglobulin
Description : 16.18 Thyrotropin exerts the following actions on the thyroid gland except: A. Increases vascularity B. Inhibits proteolysis of thyroglobulin C. Induces hyperplasia and hypertrophy D. Promotes iodide trapping
Description : In the intact animal H2 receptor antagonists potentiate the following action of histamine: A. Cardiac stimulation B. Fall in blood pressure C. Uterine relaxation D. Bronchospasm
Last Answer : D. Bronchospasm
Description : Actions of morphine include the following except: A. Vagal stimulation B. Miosis C. Antiemetic D. Postural hypotensio
Last Answer : C. Antiemetic
Description : Neostigmine reverses the following actions of d-tubocurarine except: A. Motor weakness B. Ganglionic blockade C. Histamine release D. Respiratory paralysis
Last Answer : C. Histamine release
Description : As a plasma expander, dextran has the following advantages except: A. It exerts oncotic pressure similar to plasma proteins B. It keeps plasma volume expanded for about 24 hours C. It is nonpyrogenic D. It does not interfere with grouping and cross matching of blood
Last Answer : D. It does not interfere with grouping and cross matching of blood
Description : The following is true about actions of ethylalcohol: A. It exerts anticonvulsant action followed by lowering of seizure threshold B. It lowers pain threshold C. It increases confidence and reduces number of errors D. It increases heat production and helps to keep warm in cold weather
Last Answer : A. It exerts anticonvulsant action followed by lowering of seizure threshold
Description : In patients with benign prostatic hypertrophy, finasteride exerts the following action/actions: A. Reduces size of the prostate gland B. Increases peak urinary flow rate C. Relaxes vesical sphincter D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Hydrocortisone exerts the following actions: A. Increases both K+ and Ca2+ excretion B. Decreases both K+ and Ca2+ excretion C. Decreases K+ but increases Ca2+ excretion D. Increases K+ but decreases Ca2+ excretion
Last Answer : A. Increases both K+ and Ca2+ excretion
Description : Surface anaesthesia is used for the following except: A. Ocular tonometry B. Urethral dilatation C. Tooth extraction D. Anal fissure
Last Answer : C. Tooth extraction
Description : Histamine causes all the following except (A) Stimulation of gastric secretion (B) Vasoconstriction (C) Pruritus (D) Increase in capillary permeability
Last Answer : Answer : B
Description : Morphine induced fall in blood pressure involves the following factors except: A. Direct cardiac depression B. Direct reduction of vascular tone C. Vasomotor centre depression D. Histamine release
Last Answer : A. Direct cardiac depression
Description : Tachyphylaxis to many actions on repeated injection is a feature of the following autacoid: A. Histamine B. 5-Hydroxytryptamine C. Bradykinin D. Prostaglandin E2
Last Answer : B. 5-Hydroxytryptamine
Description : Succinylcholine is the preferred muscle relaxant for tracheal intubation because: A. It produces rapid and complete paralysis of respiratory muscles with quick recovery B. It does not alter heart rate or ... C. It does not cause histamine release D. It does not produce postoperative muscle soreness
Last Answer : A. It produces rapid and complete paralysis of respiratory muscles with quick recovery
Description : The following is true of loperamide except: A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action B. It acts on the opioid receptors in the gut C. It increases ... of the intestines D. It inhibits intestinal secretion by binding to calmodulin in the mucosal cells
Last Answer : A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action
Description : Omeprazole exerts practically no other action except inhibition of gastric acid secretion because: A. It transforms into the active cationic forms only in the acidic pH of the gastric juice B. Its ... forms are unable to diffuse out from the gastric parietal cell canaliculi D. All of the above
Last Answer : D. All of the above
Description : In parkinsonian patients levodopa exerts the following effects except: A. Reduces skeletal muscle contractility B. Decreases muscle tone C. Increases locomotor activity D. Inhibits muscle tremor
Last Answer : A. Reduces skeletal muscle contractility
Description : The following is true of raloxifene except: A. It acts as an estrogen agonist in bone B. It exerts estrogen antagonistic action on endometrium C. It increases risk of developing breast cancer D. It can induce/aggravate menopausal hot flushes
Last Answer : C. It has additional androgenic acitivity
Description : Dilatation of the peripheral arterial blood vessels can be caused by: a. thromboxane A2 b. adenosine diphosphate c. endothelin d. prostaglandins
Last Answer : prostaglandins
Description : The following action of adrenaline is not mediated by β receptors: A. Dilatation of blood vessels B. Dilatation of pupil C. Bronchodilation D. Renin release from kidney
Last Answer : B. Dilatation of pupil
Description : The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation
Last Answer : B. Intestinal relaxation
Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity
Last Answer : A. Exerts depressant effects on the CNS at relatively low doses
Description : All of the following contribute to the antihypertensive action of propranolol except: A. Direct vasodilatation B. Decreased renin release from kidney C. Adaptation of blood vessels to reduced cardiac output D. Less noradrenaline release from sympathetic nerve endings
Last Answer : A. Direct vasodilatation
Description : Insulin release from pancreatic β cells is augmented by the following except: A. Ketone bodies B. Glucagon C. Vagal stimulation D. Alfa adrenergic agonists
Last Answer : D. Alfa adrenergic agonist
Description : A drug which preferentially dilates autoregulatory coronary arterioles with little effect on large conducting vessels is likely to: A. Evoke coronary steal phenomenon B. Mitigate classical angina but not ... . Decrease total coronary blood flow in healthy subjects D. Avert ECG changes of ischaemia
Last Answer : A. Evoke coronary steal phenomenon
Description : Actions of bradykinin include the following except: A. Fall in blood pressure B. Cardiac depression C. Increase in capillary permeability D. Bronchoconstriction
Last Answer : B. Cardiac depression
Description : Actions of thyroxine include the following except: A. Induction of negative nitrogen balance B. Reduction in plasma cholesterol level C. Fall in plasma free fatty acid level D. Rise in blood sugar leve
Last Answer : C. Fall in plasma free fatty acid level
Description : 17.5 Actions of thyroxine include the following except: A. Induction of negative nitrogen balance B. Reduction in plasma cholesterol level C. Fall in plasma free fatty acid level D. Rise in blood sugar level
Last Answer : D. Rise in blood sugar level
Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization
Last Answer : D. Inhibiting peripheral glucose utilization
Description : The most prominent and dose related side effect of salbutamol is: A. Rise in blood pressure B. Muscle tremor C. Hyperglycaemia D. Central nervous system stimulation
Last Answer : B. Muscle tremor
Description : Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia
Last Answer : B. Increased occult blood loss in stools
Description : Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above
Last Answer : Ans: B
Description : The fall in blood pressure caused by d-tubocurarine is due to: A. Reduced venous return B. Ganglionic blockade C. Histamine release D. All of the above
Description : Fall in blood pressure caused by larger doses of histamine is blocked by: A. H1 antihistaminics alone B. H2 antagonists alone C. Combination of H1 and H2 antagonists D. None of the above
Last Answer : C. Combination of H1 and H2 antagonists
Description : What is true of thalidomide: A. It exerts antitumour activity in some solid malignant tumours B. It ameliorates cancer associated cachexia C. It exerts antileprotic action D. All of the above
Last Answer : B. It ameliorates cancer associated cachexia
Description : The following is/are true of mesalazine: A. It exerts mainly local antiinflammatory action in the lower gut B. It is a broad spectrum antidiarrhoeal drug C. It can be administered as a retention enema D. Both 'A' and 'C
Last Answer : D. Both 'A' and 'C
Description : What is true of tamoxifen: A. It can induce endometrial proliferation in postmenopausal women B. It exerts antiestrogenic activity in bone C. It raises LDL-cholesterol levels D. It is ineffective in estrogen receptor-negative breast cancer
Last Answer : A. It can induce endometrial proliferation in postmenopausal women
Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above
Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition
Description : Metoclopramide has the following actions except: A. Increases lower esophageal sphincter tone B. Increases tone of pyloric sphincter C. Increases gastric peristalsis D. Increases intestinal peristalsis
Last Answer : B. Increases tone of pyloric sphincter
Description : Actions of adenosine include the following except: A. Depression of A-V node B. Coronary vasodilatation C. Bronchodilatation D. Fall in BP
Last Answer : C. Bronchodilatation
Description : Imipramine produces the following actions except: A. Euphoria B. Dryness of mouth C. Tachycardia D. Lowering of seizure threshold
Last Answer : A. Euphoria
Description : Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects
Last Answer : D. It produces prominent extrapyramidal side effect