Fall in blood pressure caused by larger doses of histamine is blocked by: A. H1 antihistaminics alone B. H2 antagonists alone C. Combination of H1 and H2 antagonists D. None of the above

Fall in blood pressure caused by larger doses of
histamine is blocked by:
A. H1 antihistaminics alone
B. H2 antagonists alone
C. Combination of H1 and H2 antagonists
D. None of the above
by

1 Answer

Answer :

C. Combination of H1 and H2 antagonists
by

Related questions

Fall in blood pressure caused by larger doses of histamine is blocked by: A. H1 antihistaminics alone B. H2 antagonists alone C. Combination of H1 and H2 antagonists D. None of the above

Description : Fall in blood pressure caused by larger doses of histamine is blocked by: A. H1 antihistaminics alone B. H2 antagonists alone C. Combination of H1 and H2 antagonists D. None of the above

Last Answer : C. Combination of H1 and H2 antagonists

Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above

Description : Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above

Last Answer : Ans: C

In the intact animal H2 receptor antagonists potentiate the following action of histamine: A. Cardiac stimulation B. Fall in blood pressure C. Uterine relaxation D. Bronchospasm

Description : In the intact animal H2 receptor antagonists potentiate the following action of histamine: A. Cardiac stimulation B. Fall in blood pressure C. Uterine relaxation D. Bronchospasm

Last Answer : D. Bronchospasm

The following class(es) of drugs are clinically beneficial in bronchial asthma: A. Histamine H1 receptor antagonists B. Platelet activating factor (PAF) antagonists C. Leukotriene ( cys LT1) receptor antagonists D. All of the above

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The following receptor has an intrinsic ion channel: A. Histamine H1 receptor B. Histamine H2 receptor C. Adrenergic alfa receptor D. GABA-benzodiazepine receptor

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Benefit afforded by certain H1 antihistaminics in the following condition is not based on antagonism of histamine: A. Dermographism B. Insect bite C. Common cold D. Seasonal hay fever

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The second generation H1 antihistaminics have the following advantages except: A. Lack of anticholinergic side effects B. Lack of alcohol potentiating potential C. Recipient can drive motor vehicles D. Good antipruritic action

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Last Answer : D. Good antipruritic action

The fall in blood pressure caused by d-tubocurarine is due to: A. Reduced venous return B. Ganglionic blockade C. Histamine release D. All of the above

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The β3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

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Last Answer : A. Is not blocked by the conventional doses of propranolol

The β 3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

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Last Answer : A. Is not blocked by the conventional doses of propranolol

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Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above

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Last Answer : Ans: B

The following receptor has an intrinsic ion channel: A. Histamine H1 receptor B. Histamine H2 receptor C. Adrenergic alfa receptor D. GABA-benzodiazepine receptor

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Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked postural hypotension C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

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The most important receptor involved in cytotoxic drug induced vomiting is: A. Histamine H1 receptor B. Serotonin 5-HT3 receptor C. Dopamine D2 receptor D. Opioid μ receptor

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Choose the correct statement about pentazocine: A. It causes bradycardia and fall in blood pressure B. Its subjective effects are pleasurable at low doses but turn unpleasant at high doses C. It induces vomiting frequently D. It substitutes for morphine in dependent subjects

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Last Answer : B. Its subjective effects are pleasurable at low doses but turn unpleasant at high doses

Morphine induced fall in blood pressure involves the following factors except: A. Direct cardiac depression B. Direct reduction of vascular tone C. Vasomotor centre depression D. Histamine release

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The following class of gastric antisecretory drug also reduce gastric motility and have primary effect on juice volume, with less marked effect on acid and pepsin content: A. Histamine H2 blockers B. Anticholinergics C. Proton pump inhibitors D. Prostaglandins

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Which histamine H2 blocker has most marked inhibitory effect on microsomal cytochrome P-450 enzyme: A. Cimetidine B. Ranitidine C. Roxatidine D. Famotidine

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Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 blockers inhibit the proton pump in gastric mucosa C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa D. Histamine, acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa

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Last Answer : Ans: A

The conventional H1 antihistaminics possess the following additional properties except: A. Local anaesthetic B. Vasopressor C. Antiarrhythmic D. Catecholamine potentiating

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H1 antihistaminics are beneficial in: A. All types of allergic disorders B. Certain type I allergic reactions only C. Certain type IV allergic reactions only D. Bronchial asthma

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The following does not apply to cancer chemotherapy: A. Each treatment with a cytotoxic drug kills a constant number of malignant cells B. Drugs are generally used at maximum tolerated doses C. The same regimen which is palliative for a large solid tumour may be curative after surgical removal of the tumour D. Combination regimens using several drugs in succession are superior to single drug used continuously

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Fixed dose combination formulations are not necessarily appropriate for: A. Drugs administered in standard doses B. Drugs acting by the same mechanism C. Antitubercular drugs D. Antihypertensive drugs

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Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. Used alone, its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

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Last Answer : C. Used alone, its effective doses produce intolerable side effect

A ball is allowed to fall freely from a height of 3 metres on to a fixed plate. If the successive rebound heights are h1, h2, h3 a.5 metres b.4.25 metre c.0.5 metre d.1 metre e.Zero

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Succinylcholine is the preferred muscle relaxant for tracheal intubation because: A. It produces rapid and complete paralysis of respiratory muscles with quick recovery B. It does not alter heart rate or blood pressure C. It does not cause histamine release D. It does not produce postoperative muscle soreness

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Choose the correct statement in relation to treatment of urinary tract infection (UTI): A. Majority of UTIs are caused by gram positive bacteria B. Smaller doses of the antimicrobial agent suffice for lower UTI C. Fluid restriction is recommended so that the antimicrobial drug gets concentrated in urine D. Most acute UTIs are treated with a combination antimicrobial regimen

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The following is not a feature of second generation antihistaminics: A. Nonimpairment of psychomotor performance B. High antimotion sickness activity C. Absence of anticholinergic/anti5 -HTa ctions D. Additional mechanisms of antiallergic action

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A 1-kg steam-water mixture at 1.0 MPa is contained in an inflexible tank. Heat is added until the pressure rises to 3.5 MPa and the temperature to 400°. Determine the heat added.  a) 1378.7 kJ  b) 1348.5 kJ  c) 1278,7 kJ  d) 1246,5 kJ Formula: Q = (h2 – p2v2) –(h1 –p1v1)

Description : A 1-kg steam-water mixture at 1.0 MPa is contained in an inflexible tank. Heat is added until the pressure rises to 3.5 MPa and the temperature to 400°. Determine the heat added.  a) 1378.7 kJ  b) 1348.5 kJ  c) 1278,7 kJ  d) 1246,5 kJ Formula: Q = (h2 – p2v2) –(h1 –p1v1)

Last Answer : 1378.7 kJ

The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug

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Last Answer : Ans: D

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Last Answer : D. Ratio of H1:H2 blockade produced by the drug

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

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Last Answer : D. Ratio of H1:H2 blockade produced by the drug

Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy C. Lack of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals

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Last Answer : D. Potential to induce cough in susceptible individuals

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Which of the following is not the basis for subclassifying β adrenergic receptors into β1 and β2 : A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

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The following statement is not true of log dose-response curve: A. It is almost linear except at the ends B. It is a rectangular hyperbola C. It facilitates comparison of different agonists D. It can help in discriminating between competitive and noncompetitive antagonists

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Last Answer : B. It is a rectangular hyperbola

Down regulation of receptors can occur as a consequence of: A. Continuous use of agonists B. Continuous use of antagonists C. Chronic use of CNS depressants D. Denervation

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Last Answer : A. Continuous use of agonists

Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

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Last Answer : C. Both ligand recognition and signal transduction

Leukotriene antagonists are used in bronchial asthma: A. For terminating acute attacks B. As monotherapy in place of β2 agonists C. As adjuvants to β2 agonists for avoiding corticosteroids D. As nebulized powder in refractory cases

Description : Leukotriene antagonists are used in bronchial asthma: A. For terminating acute attacks B. As monotherapy in place of β2 agonists C. As adjuvants to β2 agonists for avoiding corticosteroids D. As nebulized powder in refractory cases

Last Answer : C. As adjuvants to β2 agonists for avoiding corticosteroids

The bladder trigone and prostatic muscles are relaxed by: A. Adrenergic α1 agonists B. Adrenergic α1 antagonists C. Adrenergic α2 agonists D. Adrenergic α2 antagonists

Description : The bladder trigone and prostatic muscles are relaxed by: A. Adrenergic α1 agonists B. Adrenergic α1 antagonists C. Adrenergic α2 agonists D. Adrenergic α2 antagonists

Last Answer : B. Adrenergic α1 antagonists

Which of the following is not the basis for subclassifying β adrenergic receptors into β 1 and β 2: A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

Description : Which of the following is not the basis for subclassifying β adrenergic receptors into β 1 and β 2: A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

Last Answer : C. Transducer pathway of response effectuation

The most important receptor involved in cytotoxic drug induced vomiting is (a) Histamine H1 receptor (b) Serotonin 5-HT3 receptor (c) Dopamine D2 receptor (d) Opioid µ receptor

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Last Answer : Ans: B

Which of the following is a selective H1 receptor agoinist ? (a) 4-methyl histamine (b) Impromidine (c) 2-Thiazolyl ethylamine (d) Mepyramine

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Last Answer : Ans: C

The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla

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Last Answer : B. Direct action on vascular smooth muscle causing vasodilatation

Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

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