Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia
Last Answer : Ans: B
Description : The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis
Last Answer : C. Naloxone is largely ineffective in reversing its effects
Description : Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine
Last Answer : A. Pentazocine
Description : Which of the following is an agonist-antagonist type of opioid analgesic: A. Pethidine B. Pentazocine C. Fentanyl D. Buprenorphine
Last Answer : B. Pentazocine
Description : Select the analgesic which acts through opioid as well as additional spinal monoaminergic mechanisms: A. Tramadol B. Ethoheptazine C. Dextropropoxyphene D. Alfentanil
Last Answer : A. Tramado
Description : The following opioid analgesic is similar to codeine in pharmacological profile but is less constipating: A. Methadone B. Buprenorphine C. Butorphanol D. Dextropropoxyphene
Last Answer : D. Dextropropoxyphene
Description : Indicate the opioid analgesic that is used as transdermal patch for chronic and cancer pain: A. Morphine B. Pentazocine C. Fentanyl D. Tramadol
Last Answer : The distinctive feature(s) of methadone compared to morphine is/are: A. High oral bioavailability B. High plasma protein and tissue binding C. Delayed and milder withdrawal symptoms in dependent subjects D. All of the above
Description : Apraclonidine is a clonidine congener which is used: A. To suppress opioid withdrawal syndrome B. To suppress menopausal syndrome C. As Analgesic D. To reduce intraocular tension
Last Answer : D. To reduce intraocular tension
Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor
Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis
Description : The main advantage of ketorolac over aspirin is that ketorolac (a) Can be combined more safely with an opioid such as codeine (b) Can be obtained as an over-the-counter agent (c) Does not ... (e) Is less likely to cause acute renal failure in patients with some preexisting degree of renal impairment
Last Answer : Ans: D
Description : Select the drug which is neither analgesic, nor antiinflammatory, nor uricosuric, but is highly efficacious in acute gout: A. Prednisolone B. Colchicine C. Naproxen D. Sulfinpyrazone
Last Answer : B. Colchicine
Description : Choose the correct statement about paracetamol: A. It increases uric acid excretion B. It is the most common drug implicated in causing analgesic nephropathy C. In equianalgesic doses it is safer than aspirin D. It stimulates cellular metabolism
Last Answer : C. In equianalgesic doses it is safer than aspirin
Description : Choose the action for which the dose of aspirin required is the lowest: A. Analgesic B. Antipyretic C. Antiinflammatory D. Antiplatelet aggregatory
Last Answer : D. Antiplatelet aggregatory
Description : The plasma half life of aspirin (along with salicylic acid released from it): A. Remains constant irrespective of dose B. Is longer for antiinflammatory doses compared to that for analgesic ... for antiinflammatory doses compared to that for analgesic dose D. Can be shortened by acidifying urine
Last Answer : B. Is longer for antiinflammatory doses compared to that for analgesic dose
Description : Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia
Last Answer : B. Increased occult blood loss in stools
Description : Select the opioid antagonist that is preferred for long term opioid blockade therapy of post addicts: A. Nalorphine B. Naloxone C. Naltrexone D. Nalbuphine
Last Answer : C. Naltrexone
Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure
Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.
Description : Choose the correct statement about aspirin: A. In an afebrile patient acute overdose of aspirin produces hypothermia B. Aspirin suppresses flushing attending large dose of nicotinic acid C. Aspirin ... acute rheumatic fever D. Long term aspirin therapy increases the risk of developing colon cancer
Last Answer : B. Aspirin suppresses flushing attending large dose of nicotinic acid
Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above
Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition
Description : Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine
Description : Choose the correct statement about methenamine (hexamine): A. It acts by getting converted to mandelic acid in the urinary tract B. It releases formaldehyde in acidic urine which inturn kills ... acute urinary tract infections D. It is the preferred urinary antiseptic in patients with liver disease
Last Answer : B. It releases formaldehyde in acidic urine which inturn kills bacteria
Description : The preferred drug for controlling an acute exacerbation of ulcerative colitis is: A. Prednisolone B. Sulfasalazine C. Mesalazine D. Vancomycin
Last Answer : . Prednisolone
Description : The preferred route of administration of streptokinase in acute myocardial infarction is: A. Intravenous B. Subcutaneous C. Intracoronary
Last Answer : A. Intravenous
Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Ganciclovir is preferred over acyclovir in the following condition: A. Herpes simplex keratitis B. Herpes zoster C. Chickenpox D. Cytomegalovirus retinitis in AIDS patient
Last Answer : D. Cytomegalovirus retinitis in AIDS patients
Description : Arginine vasopressin is preferred over desmopressin in the following condition: A. Diabetes insipidus B. Bedwetting in children C. Bleeding esophageal varices D. Bleeding in haemophilia
Last Answer : C. Bleeding esophageal varices
Description : Paracetamol has the following advantage(s) over NSAIDs: A. It is the first choice analgesic for majority of osteoarthritis patients B. It can be given safely to all age groups from infants to elderly C. It is not contraindicated in pregnant or breast feeding women D. All of the above
Last Answer : D. All of the above
Description : Chemical name of aspirin (an analgesic drug) is (A) Acetylsalicylic acid (B) Nictonic acid (C) Calcium acetate (D) Methyl salicylate
Last Answer : (A) Acetylsalicylic acid
Description : The following is true of loperamide except: A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action B. It acts on the opioid receptors in the gut C. It increases ... of the intestines D. It inhibits intestinal secretion by binding to calmodulin in the mucosal cells
Last Answer : A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action
Description : 4 Choose the correct statement about the role of opioid antimotility drugs in the management of diarrhoeas: A. They are used to control diarrhoea irrespective of its etiology B. They should ... antimicrobial therapy of diarrhoea D. They are the drugs of choice in irritable bowel syndrome diarrhoea
Last Answer : B. They should be used only as a short-term measure after ensuring that enteroinvasive organisms are not involved
Description : The opioid antidiarrhoeal drugs act by the following mechanism(s): A. They relax the intestinal smooth muscle B. They inhibit intestinal peristalsis C. They promote clearance of intestinal pathogens Aim4aiims.in D. All of the above
Last Answer : B. They inhibit intestinal peristalsis
Description : The following statement is true about endogenous opioid peptides: A. They activate only μ opioid recepors B. They do not occur in peripheral tissues C. They mediate stress induced analgesia D. Naloxone fails to antagonise their actio
Last Answer : C. They mediate stress induced analgesia
Description : Select the correct statement about Naloxone: A. It equally blocks μ, κ and δ opioid receptors B. It blocks μ receptors at lower doses than those needed for others C. It blocks κ receptors at lower doses than those needed for others D. It blocks δ receptors at lower doses than those needed for others
Last Answer : B. It blocks μ receptors at lower doses than those needed for others
Description : The following are pure opioid antagonists except: A. Nalmfene B. Nalbuphine C. Naloxone D. Naltrexone
Last Answer : B. Nalbuphine
Description : Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia
Last Answer : C. Mediates low ceiling respiratory depression
Description : Morphine has high affinity for the following opioid receptor(s): A. μ (Mu) B. κ (Kappa) C. δ (Delta) D. All of the above
Last Answer : A. μ (Mu
Description : The following opioid is more potent than morphine: A. Pethidine B. Fentanyl C. Dextropropoxyphene D. Tramadol
Last Answer : B. Fentanyl
Description : Select the receptor that is located intracellularly: A. Opioid μ receptor B. Steroid receptor C. Prostaglandin receptor D. Angiotensin receptor
Last Answer : B. Steroid receptor
Description : The most important receptor involved in cytotoxic drug induced vomiting is: A. Histamine H1 receptor B. Serotonin 5-HT3 receptor C. Dopamine D2 receptor D. Opioid μ receptor
Last Answer : B. Serotonin
Description : Instead of being effective in hyperuricaemia following drug is contradictred in the treatment of gout (a) Indomethacin (b) Diclofenac (c) Piroxicam (d) Aspirin
Description : Pentazocine differs from morphine in that: A. It is inactive by the oral route B. It does not produce physical dependence C. It has a lower ceiling of analgesic effect D. Its action is not blocked by naloxone
Last Answer : C. It has a lower ceiling of analgesic effec
Description : Nalorphine is nearly equipotent analgesic as morphine, but is not used clinically as an analgesic because: A. It causes more marked respiratory depression B. It has higher abuse potential C. It antagonises the action of morphine D. It produces prominent dysphoric effects
Last Answer : D. It produces prominent dysphoric effects
Description : Choose the correct statement about codeine: A. It has a lower oral: parenteral activity ratio than morphine B. It is devoid of abuse liability C. It is a weaker analgesic than morphine D. It is a more potent antitussive than morphine
Last Answer : C. It is a weaker analgesic than morphine
Description : The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling
Last Answer : B. Its active metabolite penetrates blood-brain barrier better than morphine
Description : Barbiturates exert the following actions except: A. Anticonvulsant B. Analgesic C. Antianxiety D. Respiratory depressant
Last Answer : B. Analgesic
Description : s a general anaesthetic, halothane has the following advantages except: A. Very good analgesic action B. Noninflammable and nonexplosive C. Reasonably rapid induction of anaesthesia D. Pleasant and nonirritating
Last Answer : A. Very good analgesic action
Description : Select the correct statement about nitrous oxide: A. It irritates the respiratory mucosa B. It has poor analgesic action C. It is primarily used as a carrier and adjuvant to other anaesthetics D. It frequently induces post anaesthetic nausea and retching
Last Answer : C. It is primarily used as a carrier and adjuvant to other anaesthetics
Description : Sustained/controlled release oral dosage form is appropriate for the following type of drug: A. An antiarthritic with a plasma half life of 24 hr B. A sleep inducing hypnotic with a plasma half life of ... 3 hours D. An analgesic with a plasma half life of 6 hours used for relief of casual headache
Last Answer : C. An antihypertensive with a plasma half life of 3 hours
Description : The following antiinflammatory analgesic has been cleared for pediatric use: A. Indomethacin B. Ibuprofen C. Ketorolac D. Piroxicam
Last Answer : B. Ibuprofen