Description : ‘Coronary steal phenomenon’ has been noted most frequently with (a) Glyceryl trinitrate (b) Dipyridamole (c) Propranolol (d) Diltiazem
Last Answer : Ans: B
Description : Started within 4-6 hours of acute myocardial infarction, which of the following drug(s) can reduce the area of necrosis and the attendant mortality: A. Propranolol B. Glyceryl trinitrate C. Lignocaine D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is: A. Increase in total coronary blood flow B. Redistribution of coronary blood flow C. Reduction of cardiac preload D. Reduction of cardiac afterload
Last Answer : C. Reduction of cardiac preload
Description : Blood flow in the following vascular bed generally decreases under the influence of glyceryl trinitrate: A. Coronary B. Cutaneous C. Renal D. Cranial
Last Answer : C. Renal
Description : The following drug is used to reduce the frequency of angina pectoris as well as to terminate an acute attack: A. Isosorbide dinitrate B. Pentaerythritol tetranitrate C. Diltiazem D. Dipyridamole
Last Answer : A. Isosorbide dinitrate
Description : The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is (a) Increase in total coronary blood flow (b) Redistribution of coronary blood flow (c) Reduction of cardiac preload (d) Reduction of cardiac after load
Last Answer : Ans: C
Description : A drug which preferentially dilates autoregulatory coronary arterioles with little effect on large conducting vessels is likely to: A. Evoke coronary steal phenomenon B. Mitigate classical angina but not ... . Decrease total coronary blood flow in healthy subjects D. Avert ECG changes of ischaemia
Last Answer : A. Evoke coronary steal phenomenon
Description : The following procedure for rapid lowering of BP in hypertensive urgency/emergency has been abandoned: A. Sublingual/oral nifedipine B. Intravenous glyceryl trinitrate infusion C. Intravenous sodium nitroprusside infusion D. Intravenous esmolol injection
Last Answer : A. Sublingual/oral nifedipine
Description : Higher incidence of myocardial infarction and increased mortality has been noted with the use of the following antihypertensive drug: A. Nifedipine B. Verapamil C. Diltiazem D. Lisinopril
Last Answer : A. Nifedipine
Description : Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which ... a long duration of action D. Sod. nitroprusside has additional K+ channel opening action
Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different
Description : Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate
Last Answer : C. Sodium nitroprusside
Description : A patient suffers from episodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from: A. Angina pectoris B. Biliary colic C. Esophageal spasm D. Any of the abov
Last Answer : D. Any of the abov
Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route ... suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion
Last Answer : D. Slow intravenous infusion
Description : Glyceryl trinitrate is administered by the following routes except: A. Oral B. Sublingual C. Intramuscular D. Intravenous
Last Answer : C. Intramuscular
Description : Nitrate tolerance is least likely to develop with the use of: A. Sustained release oral glyceryl trinitrate B. Sublingual glyceryl trinitrate C. Transdermal glyceryl trinitrate D. Oral pentaerythritol tetranitrate
Last Answer : B. Sublingual glyceryl trinitrate
Description : Select the organic nitrate which undergoes minimal first-pass metabolism in the liver: A. Glyceryl trinitrate B. Isosorbide dinitrate C. Isosorbide mononitrate D. Erythrityl tetranitrate
Last Answer : C. Isosorbide mononitrate
Description : Which vasodilator is most suitable for a patient of CHF who is symptomatic even at rest and has a central venous pressure of 25 mm Hg and cardiac index 1.8 L/min/m2 : A. Glyceryl trinitrate B. Enalapril C. Hydralazine D. Nifedipine
Last Answer : B. Enalapril
Description : Glyceryl trinitrate is used in CHF for: A. Routine treatment of mild to moderate chronic heart failure B. Rapid symptom relief in acute left ventricular failure C. Arresting disease progression D. Both 'A' and 'B'
Last Answer : D. Both 'A' and 'B
Description : Which of the following drugs is most likely to accentuate varient (Prinzmetal) angina: A. Propranolol B. Atenolol C. Verapamil D. Dipyridamole
Last Answer : A. Propranolol
Description : Combined therapy with dipyridamole and warfarin is recommended in subjects with the following: A. Risk factors for coronary artery disease B. Prosthetic heart valves C. Cerebral thrombosis D. Buerger's disease
Last Answer : B. Prosthetic heart valves
Description : Higher incidence of myocardial infarction and increased mortality has been noted with the use of the following antihypertensive drug (a) Nifedipine (b) Verapamil (c) Diltiazem (d) Lisinopril
Last Answer : Ans: A
Description : The agent given sublingually in an acute attack of angina pectoris is (a) Glyceryl trinitrate (b) Amyl nitrite (c) Erythrital tetranitrate (d) Pentaerythritol tetranitrate
Description : A patient suffers from spisodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from (a) Angina pectoris (b) Biliary colic (c) Esophageal spasm (d) All of the above
Last Answer : Ans: D
Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/ ... (a) Sublingual (b) Oral (c) Intravenous bolus injection (d) Slow intravenous infusion
Description : Glyceryl trinitrate is administratered by all of the following routes except (a) Oral (b) Sublingual (c) Intramuscular (d) Intravenous
Description : Select the organic nitrate which undergoes minimal first-pass metabolism in the liver (a) Glyceryl trinitrate (b) Isosorbide dinitrate (c) Isosorbide mononitrate (d) Erythrityl tetranitrate
Description : Which of the following drugs is a class IV antiarrhythmic that is primarily indicated for the treatment of supraventricular tachyarrhythmias? (a) Lbutilide (b) Mexiletine (c) Diltiazem (d) Quinidine (e) Propranolol
Description : Maximal medical therapy for treating angina pectoris is represented by which of the following choices? (a) Diltiazem, verapamil, nitroglycerin (b) Atenolol, isoproterenol, diltiazem (c) Verapamil, nifedipine, propranolol (d) Isosorbide, atenolol, diltiazem (e) Nitroglycerin, isosorbide, atenolol
Description : Choose the drug which alters surface receptors on platelet membrane to inhibit aggregation, release reaction and to improve platelet survival in extracorporeal circulation: A. Dipyridamole B. Ticlopidine C. Aspirin D. Heparin
Last Answer : B. Ticlopidine
Description : The following drug increases cyclic-AMP in platelets and inhibits their aggregation without altering levels of thromboxane A2 or prostacyclin: A. Aspirin B. Sulfinpyrazone C. Dipyridamole D. Abciximab
Last Answer : C. Dipyridamole
Description : The following vasodilator(s) act(s) by opening K+ channels in the vascular smooth muscle: A. Dipyridamole B. Minoxidil C. Diazoxide D. Both ‘B’ and ‘C’
Last Answer : D. Both ‘B’ and ‘C
Description : Select the drug that may improve myocardial tolerance to ischaemia and reduce anginal attacks without altering heart rate, blood pressure or myocardial O2 consumption: A. Trimetazidine B. Nicorandil C. Dipyridamole D. Nicotinic acid
Last Answer : A. Trimetazidine
Description : Persistent dry cough may occur as a side effect of the following antihypertensive drug: A. Enalapril B. Atenolol C. Diltiazem D. Methyldopa
Last Answer : A. Enalapril
Description : The following antianginal drug is most likely to produce tachycardia as a side effect: A. Amlodipine B. Nifedipine C. Diltiazem D. Verapamil
Last Answer : B. Nifedipine
Description : Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem
Last Answer : B. Amiodarone
Description : Tricyclic antidepressants abolish the antihypertensive action of the following drug: A. Enalapril B. Clonidine C. Atenolol D. Diltiazem
Last Answer : B. Clonidine
Description : The calcium channel blocker used for prophylaxis of migraine but not for angina pectoris is: A. Verapamil B. Diltiazem C. Flunarizine D. Amlodipine
Last Answer : C. Flunarizine
Description : The antianginal effect of propranolol may be attributed to which one of the following (a) Block of exercise – induced tachycardia (b) Decreased end – diastolic ventricular volume (c) Dilation of consticted coronary vessels (d) Increased cardiac force (e) Increased resting heart rate
Description : Which of the following agents used in prinzmetal’s angina has spasmolytic actions, which increase coronary blood supply? (a) Nitroglycerin (b) Nifedipine (c) Timolol (d) Isosorbide mononitrate (e) Propranolol
Description : Which of the following adrenergic inhibitors acts directly on the blood vessels, producing vasodilation? a) Prazosin hydrochloride (Minipress) Minipress is a peripheral vasodilator acting ... through centrally mediated alpha-adrenergic stimulation in the brain, producing blood pressure reduction.
Last Answer : a) Prazosin hydrochloride (Minipress) Minipress is a peripheral vasodilator acting directly on the blood vessel. It is not used in angina and coronary artery disease, however, because it induces tachycardia if not preceded by administration of propranolol and a diuretic.
Description : Highest incidence of antibiotic associated pseudomembranous enterocolitis has been noted with the use of: A. Ampicillin B. Chloramphenicol C. Vancomycin D. Clindamycin
Last Answer : D. Clindamycin
Description : Prolonged painful erection of penis has been noted particularly as a side effect of: A. Doxepin B. Citalopram C. Bupropion D. Trazodone
Last Answer : D. Trazodone
Description : The following is a very potent and short acting benzodiazepine whose use as hypnotic has been noted to cause psychiatric disturbances in some cases: A. Flurazepam B. Nitrazepam C. Temazepam D. Triazolam
Last Answer : D. Triazolam
Description : Select the drug which reduces cholesterol synthesis in liver, increases expression of LDL receptors on hepatocytes and has been found to reduce mortality due to coronary artery disease: A. Simvastatin B. Nicotinic acid C. Gemfibrozil D. Colestipol (
Last Answer : A. Simvastatin
Description : Which of the following methods to induce hemostasis after sheath removal post Percutaneous Transluminal Coronary Angioplasty is the least effective? a) Application of a sandbag to the area Several ... ) Application of a pneumatic compression device post PTCA has been demonstrated to be effective
Last Answer : a) Application of a sandbag to the area Several nursing interventions frequently used as part of the standard of care, such as applying a sandbag to the sheath insertion site, have not been shown to be effective in reducing the incidence of bleeding.
Description : A woman in the 28th week of pregnancy has developed pregnancy induced hypertension with a blood pressure reading of 150/100 mm Hg. Select the most appropriate antihypertensive drug for her: A. Furosemide B. Methyldopa C. Propranolol D. Captopril
Last Answer : B. Methyldopa
Description : The following antihypertensive drug has a favourable effect on plasma lipid profile: A. Prazosin B. Propranolol C. Hydrochlorothiazide D. Furosemide
Last Answer : A. Prazosin
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Description : Propranolol should not be prescribed for a patient of angina pectoris who is already receiving: A. Nifedipine B. Felodipine C. Verapamil D. Isosorbide mononitrate
Last Answer : C. Verapami
Description : Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil
Last Answer : D. Sildenafil