Description : Ciprofloxacin is not active against: A. H.influenzae B. E.coli C. Enterobacter spp. D. Bacteroides fragilis
Last Answer : D. Bacteroides fragilis
Description : The following antibiotic is a first line drug for treatment of Mycobacterium avium complex infection in AIDS patients: A. Clindamycin B. Clarithromycin C. Roxithromycin D. Erythromycin
Last Answer : B. Clarithromycin
Description : Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) ... fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis
Last Answer : Ans: E
Description : The following is true of clarithromycin except: A. It produces less gastric irritation and pain than erythromycin B. It is the most active macrolide antibiotic against Helicobacter pylori ... terfenadine or cisapride to cause cardiac arrhythmias D. It exhibits dose dependent elimination kinetics
Last Answer : C. It does not interact with terfenadine or cisapride to cause cardiac arrhythmias
Description : Which fluoroquinolone is highly active against Mycobact. leprae and is being used in alternative multidrug therapy regimens: A. Norfloxacin B. Ofloxacin C. Ciprofloxacin D. Lomefloxacin
Last Answer : B. Ofloxacin
Description : The following antibiotic is a first line drug for treatment of Mycobacterium avium complex infection in AIDS patients (a) Clindamycin (b) Clarithromycin (c) Roxithromycin (d) Erythromycin
Last Answer : Ans: B
Description : Select the antimicrobial agent that can be used to treat with both methicillin resistant and vancomycin resistant Staphylococcus aureus infection: A. Clarithromycin B. Clindamycin C. Linezolid D. Lincomycin
Last Answer : C. Linezolid
Description : The drugs used to treat Mycobact. avium complex infection in AIDS patients include the following except: A. Isoniazid B. Clarithromycin C. Ethambutol D. Ciprofloxacin
Last Answer : A. Isoniazid
Description : Mycobact. tuberculosis infection in a HIV infected patient is treated with: A. The same antitubercular regimen as HIV negative patient B. Four first line antitubercular drugs for 2 months followed ... line antitubercular drugs for 9 months D. Clarithromycin + Ciprofloxacin + Rifabutin for 12 months
Last Answer : B. Four first line antitubercular drugs for 2 months followed by a longer continuation phase of 7 months with rifampin + isoniazid
Description : Chloramphenicol is more active than tetracyclines against: A. Bateroides fragilis B. Treponema pallidum C. Streptococci D. Staphylococci
Last Answer : a
Description : Antimicrobials effective against anaerobic bacteria include the following except: A. Tobramycin B. Clindamicin C. Chloramphenicol D. Metronidazole
Last Answer : A. Tobramycin
Description : Impetigo is a skin disease caused by a. a species of Haemophilus. b. a species of Chlamydia. c. Bacteroides fragilis. d. Staphylococcus aureus.
Last Answer : d. Staphylococcus aureus.
Description : he aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzymes is: A. Kanamycin B. Sisomicin C. Amikacin D. Tobramycin
Last Answer : C. Amikacin
Description : Select the antibiotic whose dose must be reduced in patients with renal insufficiency: A. Ampicillin B. Chloramphenicol C. Tobramycin D. Erythromycin
Last Answer : C. Tobramycin
Description : Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis
Last Answer : B. It can be used topically to treat infected acne vulgaris
Description : The following is true of vancomycin except: A. It is a bactericidal antibiotic active primarily against gram positive bacteria B. It acts by inhibiting bacterial protein synthesis C. It is an alternative to penicillin for enterococcal endocarditis D. It can cause deafness as a dose related toxicity
Last Answer : B. It acts by inhibiting bacterial protein synthesis
Description : Neomycin is widely used as a topical antibiotic because: A. It is active against a wide range of bacteria causing superfecial infections B. It rarely causes contact sensitization C. It is poorly absorbed from the topical sites of application D. All of the above are correct
Last Answer : D. All of the above are correct
Description : Select the macrolide antibiotic having clinically useful antileprotic activity: A. Azithromycin B. Clarithromycin C. Erythromycin D. Roxithromycin
Description : Select the macrolide antibiotic that can be given once daily for 3 days for empirical treatment of ear-nosethroat, respiratory and genital infections: A. Erythromycin B. Azithromycin C. Roxithromycin D. Clarithromycin
Last Answer : B. Azithromycin
Description : ‘Red man syndrome’ has been associated with rapid intravenous injection of the following antibiotic: A. Vancomycin B. Clindamycin C. Cefoperazone D. Piperacillin
Last Answer : A. Vancomycin
Description : Highest incidence of antibiotic associated pseudomembranous enterocolitis has been noted with the use of: A. Ampicillin B. Chloramphenicol C. Vancomycin D. Clindamycin
Last Answer : D. Clindamycin
Description : Select the antibiotic which inhibits drug metabolizing isoenzyme CYP3A4 resulting in potentially fatal drug interaction with terfenadine: A. Erythromycin B. Clindamycin C. Gentamicin D. Vancomycin
Last Answer : A. Erythromycin
Description : Select the antibiotic(s) that can be used to treat nonspecific urethritis due to Chlamydia trachomatis: A. Azithromycin B. Doxycycline C. Clindamycin D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Cefotaxime has the following properties except: A. It is highly active against aerobic gram negative bacteria B. It is the most active cephalosporin against Pseudomonas aeruginosa C. It produces an active metabolite D. It has achieved high cure rates in serious hospital acquired infections
Last Answer : B. It is the most active cephalosporin against Pseudomonas aeruginosa
Description : The distinctive feature(s) of sparfloxacin compared to ciprofloxacin is/are: A. Enhanced activity against gram positive bacteria B. Lack of pharmacokinetic interaction with theophylline and warfarin C. Higher incidence of phototoxic reaction D. All of the above
Last Answer : D. All of the above
Description : Which fluoroquinolone has enhanced activity against gram positive bacteria and anaerobes: A. Pefloxacin B. Ciprofloxacin C. Sparfloxacin D. Norfloxacin
Last Answer : C. Sparfloxacin
Description : Concurrent use of an aminoglycoside antibiotic should be avoided with the following antibiotic: A. Ampicillin B. Vancomycin C. Ciprofloxacin D. Rifampin
Last Answer : B. Vancomycin
Description : A premature neonate suffered respiratory distress and was given an antibiotic 100 mg/kg/day orally. Over the next two days his condition worsened, he become dull, stopped feeding, developed ... most likely antibiotic given to him: A. Ampicillin B. Chloramphenicol C. Erythromycin D. Ciprofloxacin
Last Answer : B. Chloramphenico
Description : Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci
Last Answer : Ans: A
Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin
Description : Choose the antimicrobial which acts by interfering with DNA function in the bacteria: A. Chloramphenicol B. Ciprofloxacin C. Streptomycin D. Vancomycin
Last Answer : B. Ciprofloxacin
Description : The following statement is not true of sulbactam: A. It is a broad spectrum β-lactamase inhibitor B. It does not augment the activity of ampicillin against bacteria that are sensitive ... β-lactamases D. Combined with ampicillin, it is highly effective against penicillinase producing N. gonorrhoeae
Last Answer : C. It induces chromosomal β-lactamases
Description : The aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzymes is (a) Kanamycin (b) Sisomicin (c) Amikacin (d) Tobramycin
Last Answer : Ans: C
Description : Select the antibiotic whose dose must be reduced in patients with renal insufficiency (a) Ampicillin (b) Chloramphenicol (c) Tobramycin (d) Erythromycin
Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci
Description : Tinidazole differs from metronidazole in that: A. It is not active against anaerobic bacteria B. It has a broader spectrum of activity C. It has a longer elimination half life D. It has better oral absorption
Last Answer : C. It has a longer elimination half life
Description : In addition to fungi, amphotericin B is active against the following pathogen: A. Anaerobic bacteria B. Giardia C. Leishmania D. Rickettsiae
Last Answer : C. Leishmania
Description : Tetracyclines are active against the following gram negative bacteria: A. Salmonella typhi B. Pseudomonas aeruginosa C. Yersinia pestis D. All of the above
Last Answer : C. Yersinia pestis
Description : Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct
Description : The characteristic feature(s) of penicillin G is/are: A. It is unstable in aqueous solution B. Its antibacterial action is unaffected by pus and tissue fluids C. It is equally active against resting and multiplying bacteria D. Both ‘A’ and ‘B’ are correc
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : Nalidixic acid is primarily active against: A. Cocci B. Bacilli C. Gram positive bacteria D. Gram negative bacteria
Last Answer : D. Gram negative bacteria
Description : If a multibacillary leprosy patient treated with standard fixed duration multidrug therapy relapses, he should be treated with: A. The same rifampin + dapsone + clofazimine regimen B. ... + minocycline C. Clofazimine + ofloxacin + clarithromycin D. Ofloxacin + minocycline + clarithromycin
Last Answer : . The same rifampin + dapsone + clofazimine regimen
Description : Clarithromycin is used for the following: A. Multidrug resistant M.tuberculosis infection B. M.avium complex infection in AIDS patient C. M.tuberculosis infection in a patient who develops jaundice due to first line antitubercular drugs D. Both ‘A’ and ‘B’ are correct
Last Answer : B. M.avium complex infection in AIDS patient
Description : If you have ever taken the antibiotic Clindamycin, what was your experience like with it?
Last Answer : I have taken it before. I don’t know why but it tasted like chairs
Description : Highest incidence of antibiotic associated pseudo membranous enterocolitis has been noted with the use of (a) Ampicillin (b) Chloramphenicol (c) Vancomycin (d) Clindamycin
Last Answer : Ans: D
Description : A patient presents with rheumatic fever and suspected allergy to penicillin. The antibiotic of choice is: A. Chloromycetin B. Sulphonamide C. Buffered penicillin D. Erythromycin could be better if is clindamycin E. Achromycin
Last Answer : D. Erythromycin could be better if is clindamycin
Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections
Description : What is break point concentration of an antibiotic: A. Concentration at which the antibiotic lyses the bacteria B. Concentration of the antibiotic which demarkates between sensitive ... which overcomes bacterial resistance D. Concentration at which a bacteriostatic antibiotic becomes bactericida
Last Answer : . Concentration of the antibiotic which demarkates between sensitive and resistant bacteria
Description : Superinfections are more common with: A. Use of narrow spectrum antibiotics B. Short courses of antibiotics C. Use of antibiotics that are completely absorbed from the small intestines D. Use of antibiotic combinations covering both gram positive and gram negative bacteria
Last Answer : D. Use of antibiotic combinations covering both gram positive and gram negative bacteria
Description : Acquisition of inducible energy dependent efflux proteins by bacteria serves to: A. Secrete exotoxins B. Enhance virulance C. Lyse host tissue D. Confer antibiotic resistance
Last Answer : D. Confer antibiotic resistance