ndicate the anti-HIV regimen that is generally reserved for advanced cases of AIDS or for repeated treatment failures: A. Two nucleoside reverse transcriptase inhibitors (NRTIs) + one protease inhibitor (PI) B. Three NRTIs C. Two NRTIs + one non-NRTI D. One NRTI + one non-NRTI + one PI

ndicate the anti-HIV regimen that is generally
reserved for advanced cases of AIDS or for repeated
treatment failures:
A. Two nucleoside reverse transcriptase inhibitors (NRTIs) + one protease inhibitor (PI)
B. Three NRTIs
C. Two NRTIs + one non-NRTI
D. One NRTI + one non-NRTI + one PI
by

1 Answer

Answer :

D. One NRTI + one non-NRTI + one PI
by

Related questions

The initial regimen for antiretroviral therapy of previously untreated HIV patient consist of: A. Two nucleoside reverse transcriptase inhibitors (NRTIs) + one protease inhibitor (PI) B. Two NRTIs + one non-NRTI C. Three NRTIs D. Any of the above

Description : The initial regimen for antiretroviral therapy of previously untreated HIV patient consist of: A. Two nucleoside reverse transcriptase inhibitors (NRTIs) + one protease inhibitor (PI) B. Two NRTIs + one non-NRTI C. Three NRTIs D. Any of the above

Last Answer : D. Any of the above

According to current guidelines, previously untreated symptomatic HIV patients should be treated with: A. Zidovudine alone B. Zidovudine + zalcitabine C. Zidovudine + indinavir D. Any two nucleoside reverse transcriptase inhibitors + one protease inhibito

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Last Answer : D. Any two nucleoside reverse transcriptase inhibitors + one protease inhibitor

Select the drug which directly inhibits HIV-reverse transcriptase without the need for intracellular activation by phosphorylation: A. Nelfinavir B. Nevirapine C. Stavudine D. Didanosine

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Last Answer : B. Nevirapine

Which of the following is correct regarding AIDS causative agent HIV? (a) HIV is enveloped virus containing one molecule of single-stranded RNA and one molecule of reverse transcriptase. (b) HIV is enveloped virus that contains two identical molecules of single-stranded RNA and two molecules of reverse transcriptase. (c) HIV is unenveloped retrovirus. (d) HIV does not escape but attacks the acquired immune response

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Last Answer : (d) HIV does not escape but attacks the acquired immune response.

At which stage of HIV infection does one usually show symptoms of AIDS? (a) Within 15 days of sexual contact with an infected person (b) When the infected retro virus enters host cells (c) When HIV damages large number of helper T  - lymphocytes (d) When the viral DNA is produced by reverse transcriptase

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Last Answer : (c) When HIV damages large number of helper T  - lymphocytes

ndicate the drug which does not improve lower esophageal sphincter tone or prevent gastroesophageal reflux, but is used as first line treatment of gastroesophageal reflux disease: A. Sodium alginate + aluminium hydroxide gel B. Omeprazole C. Mosapride D. Famotidine

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Last Answer : B. Omeprazole

Choose the correct statement(s) about retroviral protease inhibitors: A. They act at an early step in HIV replication B. They are more active in inhibiting HIV than zidovudine C. They inhibit CYP3A4 and interact with many other drugs D. Both 'B' and 'C' are correct

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Last Answer : D. Both 'B' and 'C' are correct

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Last Answer : D. Nelfinavir

The HIV titer of an AIDS patient was found to be reduced but still detectable after 6 months of tripple drug anti-HIV therapy. The best course of action in this patient is: A. Continue the same 3 drugs for another 3 months B. Replace all 3 drugs with a set of another 3 drugs C. Replace 2 drugs and continue one previously used drug D. Replace one drug and continue two previously used drugs

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Last Answer : B. Replace all 3 drugs with a set of another 3 drugs

The following does not apply to cancer chemotherapy: A. Each treatment with a cytotoxic drug kills a constant number of malignant cells B. Drugs are generally used at maximum tolerated doses C. The same regimen which is palliative for a large solid tumour may be curative after surgical removal of the tumour D. Combination regimens using several drugs in succession are superior to single drug used continuously

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Last Answer : A. Each treatment with a cytotoxic drug kills a constant number of malignant cells

Mycobact. tuberculosis infection in a HIV infected patient is treated with: A. The same antitubercular regimen as HIV negative patient B. Four first line antitubercular drugs for 2 months followed by a longer continuation phase of 7 months with rifampin + isoniazid C. All 5 first line antitubercular drugs for 9 months D. Clarithromycin + Ciprofloxacin + Rifabutin for 12 months

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Last Answer : B. Four first line antitubercular drugs for 2 months followed by a longer continuation phase of 7 months with rifampin + isoniazid

HIV often changes its shape due to the presence of an enzyme called (1) Reverse Transcriptase (2) Enterokinase (3) Nucleotidase (4) Nucleoditase

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HIV often changes its shape due to the presence of an enzyme called (1) Reverse Transcriptase (2) Enterokinase (3) Nucleotidase (4) Nucleoditase

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Last Answer : Reverse Transcriptase

Antiretroviral treatment affords the following benefit(s) in HIV infection: A. Increases CD4 leucocyte count B. Reduces the incidence of opportunistic infections in AIDS patients C. Increases survival time in AIDS patients D. All of the above

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According to the current WHO guidelines, new (untreated) sputum smear positive cases of pulmonary tuberculosis are to be treated with the following regimen: A. Isoniazid + Rifampin + Pyrazinamide for 6 months B. Isoniazid + Thiacetazone + Rifampin for 2 months followed by isoniazid + thiacetazone for 6 months C. Isoniazid + Rifampin for 6 months with additional Pyrazinamide + Ethambutol/Streptomycin during the initial 2 months D. Isoniazid + Rifampin for 6 months with additional Pyrazinamide during the initial 2 months

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Last Answer : C. Isoniazid + Rifampin for 6 months with additional Pyrazinamide + Ethambutol/Streptomycin during the initial 2 months

Select the drug which is used to treat antibiotic associated pseudomembranous enterocolitis and is a component of anti-H.pylori triple drug regimen: A. Amoxicillin B. Vancomycin C. Metronidazole D. Clotrimazole

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The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent suppression of gastric acid enhances efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

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Choose the correct statement about topotecan: A. It is a DNA topoisomerase I inhibitor which causes single strand DNA breaks B. It is a cell cycle specific anticancer drug C. It is a COMT-inhibitor used in advanced parkinsonism D. Both 'A' and 'B' are correc

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ystemic corticosteroid therapy is not used routinely and is reserved only for severe cases of: A. Exfoliative dermatitis B. Posterior uveitis C. Acute rheumatic fever D. Hodgkin’s disease

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Last Answer : C. Acute rheumatic feve

In the short course regimen for treatment of tuberculosis, pyrazinamide and ethambutol are used for: A. Initial one month B. Initial two months C. Last two months D. Throughout the course

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The following category of drugs is not indicated in early/mild cases of Parkinson's disease: A. Central anticholinergic B. MAO-B inhibitor C. COMT inhibitor D. Nonergoline dopaminergic agonist

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What is true about human interferon α: A. It is used to treat HIV infection B. It is used to treat Kaposi‘s sarcoma in AIDS patients C. It is curative for hepatitis B virus infection D. It is active orally

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Though the following drug reduces HIV titre, it is used only to treat associated cytomegalovirus infection in AIDS patients: A. Didanosine B. Foscarnet C. Acyclovir D. Saquinavir

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Last Answer : B. Foscarnet

Choose the correct statement(s) about inhaled glucocorticoids in chronic obstructive pulmonary disease (COPD): A. They are indicated in COPD only for severe/ advanced cases B. Instituted early they retard the progression of COPD C. Their use predisposes to respiratory infections D. Both 'A' and 'B

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Last Answer : A. They are indicated in COPD only for severe/ advanced cases

Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects

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Last Answer : D. It is unlikely to produce anti-androgenic side effects

Anti-HIV drug therapy is recommended in the following category of HIV exposed subjects: A. HIV positive symptomatic patients with opportunistic infections B. HIV positive asymptomatic subjects with CD4 cell count more than 400/μl C. HIV positive asymptomatic subjects with CD4 cell count less than 200/μl D. Both 'A' and 'C

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Last Answer : C. HIV positive asymptomatic subjects with CD4 cell count less than 200/μl

The following anti-HIV drug should not be combined with zidovudine because of mutual antagonism: A. Stavudine B. Lamivudine C. Nevirapine D. Ritonavir

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Last Answer : A. Stavudine

The antiviral action of amantadine is exerted through: A. Interaction with the viral M2 protein B. Interaction with a virus directed thymidine kinase C. Inhibition of a viral protease enzyme D. Inhibition of viral RNA mediated DNA synthesi

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Last Answer : A. Interaction with the viral M2 protein

The preferred class of drugs for long term treatment of severe anxiety disorder with intermittent panic attacks is: A. Phenothiazine (chlorpromazine like) B. Azapirone (buspirone like) C. β-blocker (propranolol like) D. Selective serotonin reuptake inhibitor (sertraline like)

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Last Answer : DD. Selective serotonin reuptake inhibitor (sertraline like)

Which of the following is a specific inhibitor of the enzyme alcohol dehydrogenase and is useful in the treatment of methanol poisoning: A. Disulfiram B. Ethylene glycol C. Calcium leucovorin D. Fomepizole

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Last Answer : D. Fomepizole

fected biological sample. Antiretroviral treatment will achieve the following in him: A. Reduce the risk of contracting HIV infection B. Rule out the possibility of contracting HIV infection C. Prevent appearance of HIV seropositivity but not HIV infection in him D. None of the above

Description : fected biological sample. Antiretroviral treatment will achieve the following in him: A. Reduce the risk of contracting HIV infection B. Rule out the possibility of contracting HIV infection C. Prevent appearance of HIV seropositivity but not HIV infection in him D. None of the above

Last Answer : A. Reduce the risk of contracting HIV infection

As per WHO guidelines, treatment of failure or relapse (category II) patients of smear positive pulmonary tuberculosis differs from that of new cases in the following respect(s): A. All 5 first line antitubercular drugs are given in the initial intensive phase B. Duration of intensive phase is increased to 5 months C. Three drugs (HRE) are given in the continuation phase instead of two (HR) D. Both 'A' and 'C'

Description : As per WHO guidelines, treatment of failure or relapse (category II) patients of smear positive pulmonary tuberculosis differs from that of new cases in the following respect(s): A. All 5 first line antitubercular drugs ... are given in the continuation phase instead of two (HR) D. Both 'A' and 'C'

Last Answer : D. Both 'A' and 'C'

If a multibacillary leprosy patient treated with standard fixed duration multidrug therapy relapses, he should be treated with: A. The same rifampin + dapsone + clofazimine regimen B. Clofazimine + ofloxacin + minocycline C. Clofazimine + ofloxacin + clarithromycin D. Ofloxacin + minocycline + clarithromycin

Description : If a multibacillary leprosy patient treated with standard fixed duration multidrug therapy relapses, he should be treated with: A. The same rifampin + dapsone + clofazimine regimen B. ... + minocycline C. Clofazimine + ofloxacin + clarithromycin D. Ofloxacin + minocycline + clarithromycin

Last Answer : . The same rifampin + dapsone + clofazimine regimen

Choose the correct statement in relation to treatment of urinary tract infection (UTI): A. Majority of UTIs are caused by gram positive bacteria B. Smaller doses of the antimicrobial agent suffice for lower UTI C. Fluid restriction is recommended so that the antimicrobial drug gets concentrated in urine D. Most acute UTIs are treated with a combination antimicrobial regimen

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Last Answer : B. Smaller doses of the antimicrobial agent suffice for lower UTI

The preferred regimen for preventing duodenal ulcer relapse is: A. Maintenance antacid regimen B. Maintenance H2 blocker regimen C. On demand intermittent H2 blocker regimen D. Maintenance sucralfate regimen

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Last Answer : B. Maintenance H2 blocker regimen

The regimen(s) used for postcoital emergency contraception is/are: A. Levonorgestrel 0.5 mg + ethinylestradiol 0.1 mg taken twice 12 hour apart B. Levonorgestrel 0.75 mg taken twice 12 hour apart C. Mifepristone 600 mg single dose D. All of the abov

Description : The regimen(s) used for postcoital emergency contraception is/are: A. Levonorgestrel 0.5 mg + ethinylestradiol 0.1 mg taken twice 12 hour apart B. Levonorgestrel 0.75 mg taken twice 12 hour apart C. Mifepristone 600 mg single dose D. All of the abov

Last Answer : D. All of the abov

The following regimen is preferred for nonsurgical termination of pregnancy in the first 7 weeks: A. Intravenous oxytocin infusion B. Intramuscular carboprost C. Intravaginal mifepristone followed by intraamniotic dinoprost D. Oral mifepristone followed by oral misoprostol

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Last Answer : D. Oral mifepristone followed by oral misoprosto

AIDS is caused by the Human Immunodeficiency Virus (HIV) The transmission of HIV infection generally occurs through. (a) eating contaminated food and water (b) transfusion of contaminated blood and blood products (c) inhaling polluted air (d) shaking hand with infected person

Description : AIDS is caused by the Human Immunodeficiency Virus (HIV) The transmission of HIV infection generally occurs through. (a) eating contaminated food and water (b) transfusion of contaminated blood and blood products (c) inhaling polluted air (d) shaking hand with infected person

Last Answer : Ans:(b)

The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. Treatment with azidothymidine (AZD) appears to prolong survival when administered early in the disease c. Predisposition to infection in HIV infection is primarily due to reduction in the number of helper T cells d. Common infections in patients with AIDS are Pneumocystis, carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Description : The following statement(s) is/are true concerning HIV infection. a. Initial screening with ELISA is highly sensitive but can be associated with a false positive rate of 25% b. ... , carinii pneumonia, CMV pneumonitis, Cryptococcus meningitis, and disseminated infection due to atypical mycobacteria

Last Answer : Answer: b, c, d Acquired immunodeficiency syndrome (AIDS) is a syndrome caused by the human retrovirus (HIV-1) that infects T lymphocytes and causes severe immunosuppression. Individuals who ... to prolong survival when administered early in the course of disease and is considered routine therapy

In which organism did the reverse transcriptase enzyme which performs DNA synthesis from RNA templates first appear?

Description : In which organism did the reverse transcriptase enzyme which performs DNA synthesis from RNA templates first appear?

Last Answer : Need answer

Another name for reverse transcriptase is (A) DNA dependent DNA polymerase (B) DNA dependent RNA polymerase (C) RNA dependent DNA polymerase (D) RNA dependent RNA polymerase

Description : Another name for reverse transcriptase is (A) DNA dependent DNA polymerase (B) DNA dependent RNA polymerase (C) RNA dependent DNA polymerase (D) RNA dependent RNA polymerase

Last Answer : Answer : C

DNA directed RNA polymerase is (A) Replicase (B) Transcriptase (C) Reverse transcriptase (D) Polymerase III

Description : DNA directed RNA polymerase is (A) Replicase (B) Transcriptase (C) Reverse transcriptase (D) Polymerase III

Last Answer : Answer : B

The only correct statement about oncoviruses is (A) All the oncoviruses are RNA viruses (B) Reverse transcriptase is present in all oncoviruses (C) Viral oncogenes are identical to human protooncogens (D) Both DNA and RNA viruses can be oncoviruses

Description : The only correct statement about oncoviruses is (A) All the oncoviruses are RNA viruses (B) Reverse transcriptase is present in all oncoviruses (C) Viral oncogenes are identical to human protooncogens (D) Both DNA and RNA viruses can be oncoviruses

Last Answer : Answer : D

Reverse transcriptase catalyses (A) Synthesis of RNA (B) Breakdown of RNA (C) Synthesis of DNA (D) Breakdown of DNA

Description : Reverse transcriptase catalyses (A) Synthesis of RNA (B) Breakdown of RNA (C) Synthesis of DNA (D) Breakdown of DNA

Last Answer : Answer : C

All of the following statements about RNA-dependent DNA polymerase are true except: (A) It synthesizes DNA using RNA as a template (B) It is also known as reverse transcriptase (C) It synthesizes DNA in 5’→3’ direction (D) It is present in all the viruses

Description : All of the following statements about RNA-dependent DNA polymerase are true except: (A) It synthesizes DNA using RNA as a template (B) It is also known as reverse transcriptase (C) It synthesizes DNA in 5’→3’ direction (D) It is present in all the viruses

Last Answer : Answer : D

Reverse transcriptase activity is present in the eukaryotic: (A) DNA polymerase α (B) DNA polymerase γ (C) Telomerase (D) DNA polymerase II

Description : Reverse transcriptase activity is present in the eukaryotic: (A) DNA polymerase α (B) DNA polymerase γ (C) Telomerase (D) DNA polymerase II

Last Answer : Answer : C

Reverse transcriptase is capable of synthesising (A) RNA → DNA (B) DNA → RNA (C) RNA → RNA (D) DNA → DNA

Description : Reverse transcriptase is capable of synthesising (A) RNA → DNA (B) DNA → RNA (C) RNA → RNA (D) DNA → DNA

Last Answer : Answer : A

What are retroviruses? How do they reproduce and what is the role of the enzyme reverse transcriptase?

Description : What are retroviruses? How do they reproduce and what is the role of the enzyme reverse transcriptase?

Last Answer : Retroviruses are viruses whose genetic material is RNA. HIV and the virus of SARS (severe acute respiratory syndrome) are examples of retrovirus. These viruses inoculate their RNA into the host cell ... virus and it is also inoculated into the host cell. Virus Review - Image Diversity: retrovirus

The enzyme reverse transcriptase helps in the

Description : The enzyme reverse transcriptase helps in the

Last Answer : synthesis of DNA in the host cell.