Yes. My husband was diagnosed with deep vein thrombosis. Spent a week in a hospital. He takes his cumiden regularly, but doesn’t go in for periodic check ups. Sometimes his ankle or leg starts to swell and he used to go, “Look at this!” The first couple of times I said, “You have to go to the doctor! That could be serious!” And then he’d whine about why he didn’t want to go to the doctor. It got to the point where I wouldn’t even look and I just said “Go to the doctor.” After he realized he wasn’t going to get any sympathy from me he quit talking about it. And hasn’t gone to the doctor.