Description : The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is: A. Cloxacillin B. Vancomycin C. Erythromycin D. Amikacin
Last Answer : B. Vancomycin
Description : Select the antimicrobial agent that can be used to treat with both methicillin resistant and vancomycin resistant Staphylococcus aureus infection: A. Clarithromycin B. Clindamycin C. Linezolid D. Lincomycin
Last Answer : C. Linezolid
Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci
Last Answer : Ans: C
Description : Amoxicillin + Clavulanic acid is active against the following organism except (a) Methicillin resistant Staph. aureus (b) Penicillinase producing Staph. aureus (c) Penicillinase producing n. gonorrhoeae (d) ß-lactamase producing E. coli
Last Answer : Ans: A
Description : In a patient with culture-positive enterococcal endocarditis who has failed to respond to vancomycin because of resistance, the treatment most likely to be effective is (a) Clarithromycin (b) Erythromycin (c) Linezolid (d) Minocycline (e) Ticarcillin
Last Answer : Ans: D
Description : The following antibiotic is a first line drug for treatment of Mycobacterium avium complex infection in AIDS patients (a) Clindamycin (b) Clarithromycin (c) Roxithromycin (d) Erythromycin
Last Answer : Ans: B
Description : A woman’s neglected hangnail has developed into a mild staphylococcal cellulites. Which of the following regimens would be appropriate oral therapy? (a) Dicloxacillin 125 mg q6h (b) Vancomycin 250 mg q6h (c) Methicillin 500 mg q6h (d) Cefazolin 1 g q8h (e) Penicillin V 500 mg q6h
Description : Which one of the following antibiotics is likely to be most effective agent in the treatment of an infection due to enterococci if used in conjuction with penicillin G? (a) Amikacin (b) Gentamicin (c) Netilmicin (d) Streptomycin (e) Tobramycin
Description : A woman has an upper respiratory infection. Six years ago, she experienced an episode of bronchospasm follwing penicillin V therapy. The cultures now reveal a strain of streptococcus pneumoniae that is ... ? (a) Amoxicillin/clavulanate (b) Erythromycin (c) Ampicillin (d) cefaclor (e) Cyclacillin
Description : Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate
Description : In which of the following groups do all four drugs warrant careful monitoring for drugrelated seizures in high-risk patients? (a) Penicillin G, imipenem, amphotericin B, metronidazol ... (d) Cycloserine, metronidazole, vancomycin, sulfadiazine (e) Metronidazole, imipenem, doxycycline, erythromycin
Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin
Description : Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys ... low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics
Description : This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in ... with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin
Description : In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline
Description : _____ cause a yellow-gray-brown discoloration of teeth and stunted bones in children, which have limited its use to adults. a. Methicillin b. Vancomycin c. Tetracycline d. Erythromycin
Last Answer : c. Tetracycline
Description : Which one of the following statements about ampicillin is false? (a) Its activity is enhanced by sulbactam (b) It causes maculopapular rashes (c) It is the drug of choice for Listeria monocytogenes infection (d) It eradicates most strains of MRSA (e) Pseudomembranous colitis may occur with its use
Description : An aminoglycoside antibiotic should not be used concurrently with the following drug (a) Ampicillin (b) Vancomycin (c) Ciprofloxacin (d) Rifampin
Description : A patient needs antibiotic treatment for native valve, culture-positive infective enterococcal endocarditis. His medical history includes a severe anaphylactic reaction to penicillin G during the past year. ... /clavulanate (b) Aztreonam (c) Cefazolin plus genatamicin (d) Meropenem (e) Vancomycin
Last Answer : Ans: E
Description : Which one of the following antibiotics is a potent inducer of hepatic drug-metabolizing enzymes? (a) Ciprofloxacin (b) Cyclosporine (c) Erythromycin (d) Rifampin (e) Tetracycline
Description : The aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzymes is (a) Kanamycin (b) Sisomicin (c) Amikacin (d) Tobramycin
Description : Amoxicillin + Clavulanic acid is active against the following organisms except: A. Methicillin resistant Staph. aureus B. Penicillinase producing Staph. aureus C. Penicillinase producing N.gonorrhoeae D. β-lactamase producing E.coli
Last Answer : A. Methicillin resistant Staph. aureus
Description : A high school student presents with headache, fever, and cough of 2 day's duration. Sputum is scant and nonpurulent and a Gram stain reveals many white cells but no organisms. Since this ... initiate treatment with (a) Cefazolin (b) Clindamycin (c) Erythromycin (d) Gentamicin (e) Trovafloxacin
Description : Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for (a) Agranulocytosis patients (b) Prophylaxis of bacterial endocarditis in patients with valvular defects (c) Prophylaxis of rheumatic fever (d) Treatment of anthrax
Description : Currently the drug of choice for emperic treatment of typhoid fever is (a) Chloramphenicol (b) Cotrimoxaxole (c) Ciprofloxacin (d) Ampicillin
Description : Cloxacillin is indicated in infections caused by the following organism(s) (a) Staphylococci (b) Streptococci (c) Gonococci (d) All of the above
Description : Which of the following is not a semisynthetic penicillin ? (a) Procaine penicillin (b) Ampicillin (c) Cloxacillin (d) Carbenicillin
Description : Widespread and prolonged used of an antibiotic leads to emergence of drug resistant strains because antibiotics (a) Induce mutation in the bacteria (b) Promote conjugation among bacteria (c) Allow resistant strains to propagate preferentially (d) All of the above
Description : Highest incidence of antibiotic associated pseudo membranous enterocolitis has been noted with the use of (a) Ampicillin (b) Chloramphenicol (c) Vancomycin (d) Clindamycin
Description : Which one of the following antimicrobial drugs does not require supplementation of dosage following hemodialysis? (a) Ampicillin (b) Cefazolin (c) Ganciclovir (d) Tobramycin (e) Vancomycin
Description : Which of the following statements about vancomycin is accurate? (a) It is bacteriostatic (b) It binds to PBPs (c) It is not susceptible to penicillinase (d) It has the advantage of oral bioavailability (e) Staphylococcal enterocolitis occurs commonly with its use
Description : Spectinomycin is an aminoglycoside-like antibiotic indicated for the treatment of (a) Gram-negative bacillary septicemia (b) Tuberculosis (c) Penicillin-resistant gonococcal infections (d) Syphilis (e) Gram-negative meningitis due to susceptible organisms
Description : The following is true of linezolid except: A. It inhibits bacterial protein synthesis at an early step B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion
Last Answer : C. It is the drug of choice for enterococcal endocarditis
Description : Roxithromycin has the following advantages over erythromycin except (a) It is more effective in whooping cough (b) It causes less gastric irritation (c) It has longer plasma half-life (d) It is unlikely to precipitate theophylline toxicity
Description : Hepatitits with cholestatic jaundice occurs most frequently as an adverse reaction to the following preparation of erythromycin (a) Erythromycin base (b) Erythromycin stearate (c) Erythromycin estolate (d) Erythromycin ethylsuccinate
Description : Which out of the following antibiotics penetrates blood-CSF barrier the best (a) Erythromycin (b) Gentamicin (c) Tetracycline (d) Chloramphenicol
Description : An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was obtained. Which antibiotic could be responsible for the condition ? (a) Chloramphenicol (b) Tetracycline (c) Erythromycin (d) Genetamicin
Description : Select the antibiotic whose dose must be reduced in patients with renal insufficiency (a) Ampicillin (b) Chloramphenicol (c) Tobramycin (d) Erythromycin
Description : The drug of choice for scarlet fever is (a) Tetracycline (b) Sulfonamides (c) Penicillin (d) Chloromycetin (e) Novobiocin
Description : Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) ... fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis
Description : All of the following statements regarding pentamidine isethionate are true except (a) it is indicated for treatment or prophylaxis of infection due to Pneumocystis carinii (b) it may be ... clinically significant effect on serum glucose (d) it is effective in the treatment of leishmaniasis
Description : Amoxicillin is inferior to ampicillin for the treatment of the following infection (a) Typhoid (b) Shigella enteritis (c) Subacute bacterial endocarditis (d) Gonorrhoea
Description : Which of the following penicillins are readily destructed by stomach acid: A. Methicillin B. Cloxacillin C. Phenoxy methyl D. Penicillin G
Last Answer : D. Penicillin G
Description : Which of the following is a drug that interferes with the process of DNA production in the virus A- A.Erythromycin B- Vancomycin C- Amantadine D- Acyclovi
Last Answer : Acyclovi
Description : Select the antibiotic which inhibits drug metabolizing isoenzyme CYP3A4 resulting in potentially fatal drug interaction with terfenadine: A. Erythromycin B. Clindamycin C. Gentamicin D. Vancomycin
Last Answer : A. Erythromycin
Description : A 36-year-old woman recently treated for leukemia is admitted to hospital with malaise, chills and high fever. Gram stain of blood reveals the presence of gramnegative bacilli. The initial diagnosis is ... (b) Aztreonam (c) Cefazolin (d) Imipenem plus cilastatin (e) Ticarcillin plus clavulanic acid
Description : Piperacillin differs from carbenicillin in the following respect(s) (a) It is more active against pseudomonas aeruginosa (b) It is active against Klebsiella also (c) It is acid resistant (d) Both (a) and (b)
Description : What is break point concentration of an antibiotic ? (a) Concentration at which the antibiotic lyses the bacteria (b) Concentration of the antibiotic which demarks between sensitive ... which overcomes bacterial resistance (d) Concentration at which a bacteriostatic antibiotic becomes bactericidal
Description : The following antibiotic is a first line drug for treatment of Mycobacterium avium complex infection in AIDS patients: A. Clindamycin B. Clarithromycin C. Roxithromycin D. Erythromycin
Last Answer : B. Clarithromycin
Description : Ear Infection - to take or not to take antibiotics?
Last Answer : Any delay in treating an ear infection increases the odds of permanent damage. If I were you, I’d start the azithromycin immediately. Take the front load with food. It will be easier on your stomach.