Description : Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above
Last Answer : Ans: B
Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug
Last Answer : Ans: D
Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug
Last Answer : D. Ratio of H1:H2 blockade produced by the drug
Description : A ball is allowed to fall freely from a height of 3 metres on to a fixed plate. If the successive rebound heights are h1, h2, h3 a.5 metres b.4.25 metre c.0.5 metre d.1 metre e.Zero
Last Answer : a. 5 metres
Description : When, H1 = Total heat of air entering the coil (heating or cooling) H2 = Total heat of air leaving the coil (heating or cooling) H3 = Total heat of air at the end of ... A. cooling and humidification B. cooling and dehumidification C. heating and humidification D. heating and dehumidification
Last Answer : ANSWER : C
Description : The discharge through a V-notch weir varies as (A) H3/2 (B) H1/2 (C) H5/2 (D) H2/3
Last Answer : (C) H5/2
Description : Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)
Description : Morphine produces analgesia by acting at (a) Peripheral pain receptors (b) A spinal site (c) Suspraspinal sites (d) Both (b) and (c)
Description : Which one of the following statements about dextromethorphan is accurate? (a) Activates kappa receptors (b) Analgesia equivalent to pentazocine (c) Highly effective antiemetic (d) Less constipation than codeine (e) Use requires a prescription
Description : This drug, which does not activate opioid receptors, has been proposed as a maintenance drug in treatment programs for opioid addicts; a singly oral dose will block the effects of injected heroin for up to 48 hours (a) Amphetamine (b) Buprenorphine (c) Naloxone (d) Naltrexone (e) Propoxyphene
Description : Following mediators are involved in acute inflammation except (a) Histamine (b) Leukotrienes (c) Interferons (d) Bradykinin
Last Answer : Ans: C
Description : All of the following facts are true about non-steroidal anti-inflammatory drugs (NSAIDs) except (a) They are antipyretic (b) There is a celling effect to their analgesia (c) They can cause tolerance (d) They do not cause dependence (e) They are anti-inflammatory
Description : Potential adverse effects associated with aspirin include all of the following except (a) Gastrointestinal ulceration (b) Renal dysfunction (c) Enhanced methotrexate toxicity (d) Cardiac arrhythmias (e) Hypersensitivity asthma
Last Answer : Ans: E
Description : All of the following statements concerning an acute gouty arthritis attack are correct except (a) The diagonosis of gout is assured by a good therapeutic response to colchicines because no ... attack usually involves only one joint, most frequently the big toe (first metatarsophalangeal joint)
Last Answer : Ans: A
Description : All of the following medications should not be used routinely in pregnant patients during the third trimester except (a) Acetaminophen (b) Nonsteroidal anti-inflammatory drugs (c) Warfarin (d) Lithium (e) Aspirin
Description : Agents that often cause vasoconstriction include all of the following except (a) Angiotensin II (b) Methysergide (c) PGF2a (d) Prostacyclin (e) Thromboxane
Description : The turns ratio of transformer 'A' shown in the illustration is four to one and all taps are evenly spaced. If 120 volts were applied to terminals 'H1' and 'H3', what would appear at 'X1' and 'X2'? EL-0082 A. 15 volts B. 30 volts C. 480 volts D. 960 volts
Last Answer : Answer: A
Description : The turns ratio of device 'A' shown in the illustration is four to one and all taps are evenly spaced. If 120 volts were applied to terminals 'H1' and 'H3', what would appear at 'X1' and 'X2'? EL-0082 A. 15 volts B. 30 volts C. 480 volts D. 960 volts
Description : Nucleosome core is made of (a) H0, H2A, H2B and H3 (b) H1, H2A, H2B, H4 (c) H1, H2A, H2B, H3 and H4 (d) H2A, H2B, H3 and H4.
Last Answer : (d) H2A, H2B, H3 and H4
Description : The maximum discharge over a broad crested weir is (A) 0.384 Cd × L × H1/2 (B) 0.384 Cd × L × H3/2 (C) 1.71 Cd × L × H1/ (D) 1.71 Cd × L × H 3/
Last Answer : Answer: Option D
Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine
Last Answer : C. 2-Thiazolyl ethylamine
Description : In the manufacture of H3 PO4 (ortho); strong H2 SO4 leaching wet process as compared to electric furnace process (A) Uses lower grade phosphate rock (B) Requires lower capital investment in the plant (C) Produces lower purity acid (D) Is very costly
Last Answer : (C) Produces lower purity acid
Description : Oxytremorine is a selective agonist of muscarinic _______ receptors (a) M1 (b) M2 (c) M3 (d) M4
Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist
Description : Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures
Last Answer : C. It is a broad spectrum antiepileptic drug
Description : Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression
Last Answer : C. Tyrosine protein kinase receptors
Description : Generally the earliest manifestation of salicylism is (a) Visual disturbance (b) Excitement (c) Hyperventillation (d) Tinnitus
Description : In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is (a) Acid – base and electrolytc disturbances (b) Hypersensitivity and idiosyncratic reactions (c) Gastric mucosal damage (d) Salicylism
Description : Aspirin reduces fever by (a) Decreasing heat production in the body (b) Enhancing cutaneous blood flow (c) Inducing sweating (d) Both (b) and (c)
Description : The distinctive feature of the isoenzyme cyclooxygenase-2 is (a) It is not inhibited by indomethacin (b) It is inducible (c) It generates cytoprotective prostagladins in gastric mucosa (d) It is found only in foetal tissues
Description : Lower dose of naloxone is required to (a) Antagonise the actions of nalorphine (b) Antagonise the actions of pentazocine (c) Precipitate withdrawal in mildly morphine dependent subjects (d) Precipitate withdrawal in highly morphine dependent subjects
Description : Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis
Description : Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone
Description : Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine
Description : Morphine has high affinity for the following opioid receptor(s). (a) µ (Mu) (b) k (Kappa) (c) d (Delta) (d) All of the above
Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia
Description : Select the analgesic which acts through opioids as well as additional spinal monoaminergic mechanisms. (a) Tramadol (b) Ethoheptazine (c) Dextropropoxyphene (d) Alfentanil
Description : Which of the following opioid analgesics is similar to codeine in pharmacological profile but is less constipating ? (a) Methadone (b) Buprenorphine (c) Butorphanol (d) Dextropropoxyphene
Description : Which of the following opioids is more potent than morphine ? (a) Pethidine (b) Fentanyl (c) Dextropropoxyphene (d) Tramadol
Description : Morphine is contraindicated in head injury because (a) It does not relieve the pain of head injury (b) It can raise intracranial tension (c) It can cause constipation (d) It is liable to cause addiction
Description : Morphine dependence is characterized by (a) Marked drug seeking behavior (b) Physical dependence without psychic dependence (c) Physical as well as psychic dependence (d) Both (a) and (c)
Description : Instead of being effective in hyperuricaemia following drug is contradictred in the treatment of gout (a) Indomethacin (b) Diclofenac (c) Piroxicam (d) Aspirin
Description : In a comatose patient suspected of poisoning, which of the following findings would be against the drug being morphine (a) Selegiline (b) Chlorgiline (c) Moclobemide (d) Tranylcypromine
Description : Instead of depressing, morphine stimulates (a) Vasomotor centre (b) Edinger westphal nucleus (c) Temperature regulating centre (d) Cough centre
Description : In man sedation caused by morphine is characterized by (a) Initial excitement (b) Little or no motor incoordination (c) Rise in seizure threshold (d) All of the above
Description : Which of the following bones is affected more by glucocorticoid induced osteoporosis? (a) Femur (b) Humerus (c) Radius (d) Lumber vertebra
Description : The following adverse effect of corticosteroids is due to their mineralocorticoid action (a) Osteoporosis (b) Rise in blood pressure (c) Moon face (d) Increased susceptibility to infection