Liver failure is defined as when large portions of the liver are damaged and can no longer function. Liver failure typically happens slowly and can take many years to develop. Early signs of liver failure are not specific to the liver and can often be confused with other conditions. These early signs may include appetite loss, fatigue, nausea, weakness, swelling in the legs, and diarrhea.As the liver failure progresses, the signs are more severe and become easier to link to this condition. These signs may include:Swelling and build up of fluid in the abdomenJaundice (skin and whites of eyes turn yellow)Bleeding easily or vomiting bloodRectal bleedingExtreme fatigueMental disorientation, confusion, delirium, delusions, or hallucinationsShakiness or muscle tremorsDifficulty breathingPassing out or being unresponsiveDark colored urineIrregular bowel movementsGastrointestinal symptomsHormonal disordersHair lossHeadacheSkin problemsDizzinessSudden seizures or strokeRed, itchy eyesPersons who have any of these symptoms should seek medical care as soon as possible.Liver failure can be attributed to other conditions such as Hepatitis C, Hepatitis B, Cirrhosis, alcoholism, Hemochroamatosis (genetic condition where the body absorbs and stores too much iron), and malnutrition. If any of these conditions are present, the person should be aware of any signs of liver failure and bring them to their physician's attention.Acute liver failure is when the liver fails rapidly and can happen within days. This is much less common that gradual liver failure, but is often more severe and requires immediate hospitalization. Acute liver failure can lead to increased pressure and excessive bleeding in the brain. Acute liver failure can be caused by overdose of acetaminophen, Hepatitis A, Hepatitis B, Hepatitis C, reactions to prescription drugs or herbal medications, and eating poisonous wild mushrooms. The most common signs of acute liver failure are jaundice and pain in the upper right abdomen.