Digitalis toxicity?

Digitalis toxicity?
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DefinitionDigitalis is a medication prescribed to certain heart patients. Digitalis toxicity is a complication of digitalis therapy, or it may be occur when someone takes more than a large amount of the drug at one time. (This is called an acute ingestion.)The most common prescription form of this medication is called digoxin. Digitoxin is another form of digitalis.Causes, incidence, and risk factorsDigitalis toxicity can be caused by high levels of digitalis in the body, or a decreased tolerance to the drug. Patients with decreased tolerance may have "normal" digitalis levels in their blood.Digitalis toxicity can occur from a single exposure or chronic overmedication, or it may occur in patients with normal blood levels of digitalis if other risks are present.People with heart failure who
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Which of the following is the drug of choice for management of cardiac arrhythmias that occur in digitalis toxicity? (a) Amiodarone (b) Lidocaine (c) Propranolol (d) Sotalol (e) Prazosin

Description : Which of the following is the drug of choice for management of cardiac arrhythmias that occur in digitalis toxicity? (a) Amiodarone (b) Lidocaine (c) Propranolol (d) Sotalol (e) Prazosin

Last Answer : Ans: B

Digitalis toxicity is enhanced by co-administration of (A) Potassium (B) Quinidine (C) Diuretics (D) Antacids

Description : Digitalis toxicity is enhanced by co-administration of (A) Potassium (B) Quinidine (C) Diuretics (D) Antacids

Last Answer : Ans. B & C

Potassium therapy tends to counteract the cardiac toxicity of digitalis by: A. Reducing the affinity of sarcolemal Na+ K+ATPase for digitalis B. Suppressing ectopic automaticity enhanced by digitalis C. Promoting A-V conduction D. Both 'A' and 'B' are correct

Description : Potassium therapy tends to counteract the cardiac toxicity of digitalis by: A. Reducing the affinity of sarcolemal Na+ K+ATPase for digitalis B. Suppressing ectopic automaticity enhanced by digitalis C. Promoting A-V conduction D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

Infusion of potassium chloride is indicated in digitalis toxicity when the manifestation(s) is/are: A. Vomiting, hyperapnoea and visual disturbance B. Pulsus bigeminus with heart rate 110/min in a patient on maintenance digoxin therapy C. Ventricular tachycardia in a child who has accidentally ingested 10 digoxin tablets D. 2:1 A-V block with occasional ventricular extrasystoles

Description : Infusion of potassium chloride is indicated in digitalis toxicity when the manifestation(s) is/are: A. Vomiting, hyperapnoea and visual disturbance B. Pulsus bigeminus with heart rate 110/min ... accidentally ingested 10 digoxin tablets D. 2:1 A-V block with occasional ventricular extrasystoles

Last Answer : B. Pulsus bigeminus with heart rate 110/min in a patient on maintenance digoxin therapy

Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Description : Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Last Answer : D. Raised intraocular tension

Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Description : Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Last Answer : D. Raised intraocular tension

The biochemical mechanism of action of digitalis is associated with (a) A decrease in calcium uptake by the sarcoplasmic reticulum (b) An increase in ATP synthesis (c) A modification of the actin molecule (d) An increase in systolic intracellular calcium levels (e) A block of sodium/calcium exchange

Description : The biochemical mechanism of action of digitalis is associated with (a) A decrease in calcium uptake by the sarcoplasmic reticulum (b) An increase in ATP synthesis (c) A modification of the actin molecule (d) An increase in systolic intracellular calcium levels (e) A block of sodium/calcium exchange

Last Answer : Ans: D

The action of digitalis is enhanced by (a) Sodium (b) Calcium (c) Magnesium (d) Potassium (e) Chloride

Description : The action of digitalis is enhanced by (a) Sodium (b) Calcium (c) Magnesium (d) Potassium (e) Chloride

Last Answer : Ans: B

Overuse of digitalis may result in (a) Habituation (b) Tolerance (c) Addiction (d) Physical dependence (e) Cummulative poisoning

Description : Overuse of digitalis may result in (a) Habituation (b) Tolerance (c) Addiction (d) Physical dependence (e) Cummulative poisoning

Last Answer : Ans: E

The action of quinidine differs from that of digitalis in (a) Decreasing irritability of cardiac muscle (b) Preventing passage of impulses to the ventricle (c) Increasing irritability of heart muscle (d) Reducing conductivity (e) None of the above

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Last Answer : Ans: A

Anisocytic stomata are present in (A) Senna (B)Digitalis (C) Belladonna (D) Coca

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ignocaine is effective in the following cardiac arrhythmia(s): A. Atrial fibrillation B. Paroxysmal supraventricular tachycardia C. Digitalis induced ventricular extrasystoles D. All of the above

Description : ignocaine is effective in the following cardiac arrhythmia(s): A. Atrial fibrillation B. Paroxysmal supraventricular tachycardia C. Digitalis induced ventricular extrasystoles D. All of the above

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Milrinone is best used: A. In a patient of mild CHF B. As an additional drug alongwith conventional therapy to tide over crisis in refractory CHF C. For long-term maintenance therapy of CHF D. To suppress digitalis induced arrhythmias

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Last Answer : B. As an additional drug alongwith conventional therapy to tide over crisis in refractory CHF

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Digitalis is most suitable for treatment of CHF when it is due to: A. Cor pulmonale B. Arterio-venous shunt C. Thiamine deficiency D. Long-standing uncontrolled hypertension

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Last Answer : D. Long-standing uncontrolled hypertensio

Digitalis induced increase in refractory period of myocardial fibres is most consistent and pronounced in the: A. Atria B. Ventricles C. A-V node D. Purkinje fibres

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Last Answer : C. A-V node

The electrophysiological effects of digitalis on Purkinje fibres include the following except: A. Enhancement of resting membrane potential B. Decrease in the slope of phase-0 depolarization C. Increase in the rate of phase-4 depolarization D. Abbreviation of action potential duration

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Digitalis slows the heart in congestive heart failure by: A. Increasing vagal tone B. Decreasing sympathetic overactivity C. Direct depression of sinoatrial node D. All of the above

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