Lactic acidosis?

1 Answer

Answer :

DefinitionLactic acidosis is when lactic acid builds ups in the blood stream faster than it can be removed. Lactic acid is produced when oxygen levels in the body drop.Causes, incidence, and risk factorsThe most common cause is intense exercise. However, it can also be caused by certain diseases, such as sepsis, respiratory failure, AIDS, cancer, and kidney failure.Metformin, a common medicine used to treat Diabetes, can also cause lactic acidosis. People taking this medicine should have their electrolyte levels checked 1 - 2 weeks after starting it.SymptomsNauseaWeaknessSigns and testsBlood tests to check electrolyte levelsTreatmentThe primary treatment for lactic acidosis is correcting the underlying medical problem that causes the condition.ReferencesOh MS. Evaluation of renal function,

Related questions

Description : All the following features are found in blood chemistry in uncompensated lactic acidosis except (A) pH is decreased (B) Bicarbonate is decreased (C) pCO2 is normal (D) Anion gap is normal

Last Answer : Answer : D

Description : Anion gap is normal in (A) Hyperchloraemic metabolic acidosis (B) Diabetic ketoacidosis (C) Lactic acidosis (D) Uraemic acidosis

Last Answer : Answer : A

Description : Which of the following statements are true of elevated-anion gap metabolic acidosis? A. Hypoperfusion from the shock state rarely produces an elevated anion gap. B. Retention of sulfuric and phosphoric ... E. Use of lactated Ringer's solution is inappropriate in the treatment of lactic acidosis.

Last Answer : Answer: BC DISCUSSION: An elevated anion gap may be produced by lactic acidosis from shock or by retention of inorganic acids from uremia. Lactated Ringer's solution rapidly corrects the ... . Bicarbonate loss from diarrhea and dilutional acidosis are non-anion gap types of metabolic acidosis

Description : A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis

Last Answer : Ans: D

Description : A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Last Answer : Answers-1 The aetiology of gout can broadly be divided into cases where there is underexcretion of urate via the kidney (90%) or endogenous overproduction of uric acid (10%) although in practical ... diuretic use. Excessive dietary intake of purines is unlikely to be the main cause in this case.

Description : Why excessive intake of alcohol produces lactic acidosis? 

Last Answer : During alcohol oxidation, NADH is generated, which converts pyruvate to lactate.

Description : Metformin is preferred over phenformin because: A. It is more potent B. It is less liable to cause lactic acidosis C. It does not interfere with vitamin B12 absorption D. It is not contraindicated in patients with kidney disease

Last Answer : B. It is less liable to cause lactic acidosis

Description : The major limitation of the thiazolidinediones in the treatment of type 2 diabetes mellitus is: A. Frequent hypoglycaemic episodes B. Hyperinsulinemia C. Lactic acidosis D. Low hypoglycaemic efficacy in moderate to severe cases

Last Answer : D. Low hypoglycaemic efficacy in moderate to severe cases

Description : ___________ drug can cause lactic acidosis. a) Metformin b) Pioglitazone c) Repaglinide d) Glibenclamide

Last Answer : a) Metformin  

Description : Acidosis?

Last Answer : DefinitionAcidosis is a condition in which there is excessive acid in the body fluids. It is the opposite of alkalosis (a condition in which there is excessive base in the body ... effective breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes

Description : Metabolic acidosis?

Last Answer : DefinitionMetabolic acidosis is a condition in which there is too much acid in the body fluids.Alternative NamesAcidosis - metabolicCauses, incidence, and risk factorsMetabolic acidosis ... AlcoholCancerExercising for a very long timeLiver failureLow blood sugar (hypoglycemia)Medications such a

Description : Respiratory acidosis?

Last Answer : DefinitionRespiratory acidosis is a condition that occurs when the lungs cannot remove all of the carbon dioxide the body produces. This disrupts the body's acid-base balance causing body ... deflateDrugs that suppress breathing (including powerful pain medicines, such as narcotics, and "downers,

Description : Blood chemistry shows the following changes in compensated respiratory acidosis: (A) Increased pCO2 (B) Increased bicarbonate (C) Decreased chloride (D) All of these

Last Answer : Answer : D

Description : All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

Last Answer : Answer : D

Description : Salicylate poisoning can cause (A) Respiratory acidosis (B) Metabolic acidosis with normal anion gap (C) Metabolic acidosis with increased anion gap (D) Metabolic alkalosis

Last Answer : Answer : C

Description : Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis

Last Answer : Answer : B

Description : The initial event in respiratory acidosis is (A) Decrease in pH (B) Increase in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma bicarbonate

Last Answer : Answer : B

Description : Respiratory acidosis can occur in all of the following except (A) Pulmonary oedema (B) Hysterical hyperventilation (C) Pneumothorax (D) Emphysema

Last Answer : Answer : B

Description : Respiratory acidosis results from (A) Retention of carbon dioxide (B) Excessive elimination of carbon dioxide (C) Retention of bicarbonate (D) Excessive elimination of bicarbonate

Last Answer : Answer : A

Description : Hypercholremia is associated with (A) Hyponatremia (B) Hypernatremia (C) Metabolic alkalosis(D) Respiratory acidosis

Last Answer : Answer : B

Description : Salicylate poisoning in early stages causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis

Last Answer : Answer : D

Description : Morphine poisoning causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis

Last Answer : Answer : B

Description : Respiratory acidosis occurs in (A) Any disease which impairs respiration like emphysema (B) Renal disease (C) Poisoning by an acid (D) Pyloric stenosis

Last Answer : Answer : A

Description : Metabolic acidosis is caused in (A) Pneumonia (B) Prolonged starvation (C) Intestinal obstruction (D) Bulbar polio

Last Answer : Answer : B

Description : Metabolic acidosis is caused in (A) Uncontrolled diabetes with ketosis (B) Pneumonia (C) Intestinal Obstruction (D) Hepatic coma

Last Answer : Answer : A

Description : Meningitis and encephalitis cause (A) Metabolic alkalosis (B) Respiratory alkalosis (C) Metabolic acidosis (D) Respiratory acidosis

Last Answer : Answer : B

Description : Respiratory acidosis is caused by (A) Increase in carbonic acid relative to bicarbonate (B) Decrease in bicarbonate fraction (C) Increase in bicarbonate fraction (E) Decrease in the carbonic acid fraction

Last Answer : Answer : A

Description : Total CO2 is increased in (A) Respiratory acidosis (B) Metabolic alkalosis (C) Both respiratory acidosis and metabolic alkalosis (D) Respiratory alkalosis

Last Answer : Answer : C

Description : Plasma bicarbonate is increased in (A) Respiratory alkalosis (B) Metabolic alkalosis (C) Respiratory acidosis (D) Metabolic acidosis

Last Answer : Answer : B

Description : Plasma bicarbonate is decreased in (A) Respiratory alkalosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Metabolic acidosis

Last Answer : Answer : D

Description : Hypoglycemia depresses insulin secretion and thus increases the rate of (A) Hydrolysis (B) Reduction (C) Gluconeogenesis (D) Respiratory acidosis

Last Answer : Answer : C

Description : In severe acidosis, the output of urea is (A) Decreased (B) Slightly increased (C) Highly increased (D) Moderately increased

Last Answer : Answer : A

Description : Ammonia is excreted as ammonium salts during metabolic acidosis but the majority is excreted as (A) Phosphates (B) Creatine (C) Uric acid (D) Urea

Last Answer : Answer : D

Description : Ammonia production by the kidney is depressed in (A) Acidosis (B) Alkalosis (C) Both (A) and (B) (D) None of these

Last Answer : Answer : B

Description : Which of the following complications of TPN are appropriately managed with the listed treatment? a. Air embolism-place patient in reverse Trendelenburg and the left lateral decubitus position ... dioxide retention-decrease glucose calories and replace with fat d. Line sepsis-intravenous antibiotics

Last Answer : Answer: b, c A number of complications of TPN can occur which can be divided into three types: mechanical, metabolic, and infectious

Description : In patients receiving massive blood transfusion for acute blood loss, which of the following is/are correct? A. Packed red blood cells and crystalloid solution should be infused to restore oxygen ... should be administered with every 5 units of packed red blood cells to avoid hypocalcemia.

Last Answer : Answer: A DISCUSSION: Patients who are suffering from acute blood loss require crystalloid resuscitation as the initial maneuver to restore intravascular volume and re-establish vital signs. If 2 to 3 liters ... when the infusion of blood proceeds at a rate exceeding 1 to 2 units every 5 minutes

Description : Which of the following statements about the preparation and storage of blood components is/are true? A. Solutions containing citrate prevent coagulation by binding calcium. B. The ... cells includes development of acidosis, hyperkalemia, and decreased intracellular 2,3DPG (diphosphoglycerate).

Last Answer : Answer: ABD DISCUSSION: After blood has been collected from a donor, it is anticoagulated with a solution containing citrate, which acts by binding calcium. Blood is then separated into its ... transfusion or produce effects other than those predicted based on the content of the unit of blood

Description : Which of the following statements about respiratory acidosis are true? A. Compensation occurs by a shift of chloride out of the red blood cells. B. Renal compensation occurs rapidly. C. Retention of ... of respiratory acidosis. E. The ratio of bicarbonate to carbonic acid is less than 20:1.

Last Answer : Answer: CE DISCUSSION: Renal compensation for acute hypoventilation is relatively slow. Depression of the respiratory center by morphine can lead to respiratory acidosis. Renal retention of bicarbonate, ... into red cells combine to increase the ratio of bicarbonate to carbonic acid to 20:1

Description : Which of the following may precipitate an asthma attack? (a) Respiratory acidosis (b) Viran and bacterial infections (c) Respiratory alkalosis (d) Cranberry jiuce (e) Chocolate or Coca Cola

Last Answer : Ans: B

Description : Which of the following may be responsible for a hypokalaemic hypertension 1) Non-classical congenital adrenal hyperplasia 2) Barter's syndrome 3) Diabetic nephropathy 4) Liddle's syndrome 5) Type IV renal tubular acidosis

Last Answer : Answers-4 Liddle's syndrome is typically asscoiated with hypokalaemic hypertension and low renin and aldosterone concentrations - the so called pseudo-hyperaldosteronism. Barter's syndrome is associated ... , which may also be produced with diabetic nephropathy. Hence hyperkalaemia is more typical.

Description : A young child presents with respiratory distress, worsening over 2 days. Blood gases show a pH of 7.25, a PCO2 of 7.5kPa, a PO2 of 8.5kPa, and a base excess of -4. Which of the ... required. 4) Results are consistent with late severe asthma. 5) Bicarbonate may be necessary to correct the acidosis.

Last Answer : Answers-4 In interpreting blood gas results, the following sequence may be useful: Inspect the pH: Is it low, normal or high? Inspect the CO2: Is it low, normal or high? Inspect the PO2: Is ... excess and normal pH. Bicarbonate is usually only considered if the base deficit exceeds about -8 or 00.

Description : Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ... lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting

Last Answer : Answers-2 c - excretion of ammonium occurs when an acid urine is produced but the pH of urine is of course determined by the concentration of H+ ions d-unable to lower the pH to ... and distal nephron and this perpetuates the metabolic alkalosis until the fluid balance is restored with IV fluids.

Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+

Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.

Description : Accidental poisonings are common with both aspirin and ibuprofen, two OC drugs available in tasty chewable tablets. In cases of overdose, aspirin is more likely than ibuprofen to cause (a) ... Instability (b) Hepatic necrosis (c) Metabolic acidosis (d) Thrombocytopenia (e) Ventricular arrhythmias

Last Answer : Ans: C

Description : The toxicity spectrum of aspirin does not include (a) Increased risk of encephalopathy in children with viral infections (b) Increased risk of peptic ulcers (c) Hyperprothrombinemia (d) Metabolic acidosis (e) Respiratory alkalosis

Last Answer : Ans: C

Description : Which one of the following effects does not occur in salicylate intoxication ? (a) Hyperventilation (b) Hypothemia (c) Metabolic acidosis (d) Respiratory alkalosis (e) Tinnitus

Last Answer : Ans: B

Description : If the body experiences acidosis the respiratory center located in the medulla gets the information and induces the increase of the respiratory frequency. The increment of the respiratory frequency makes the ... of bicarbonate towards the spending of more hydrogen ions and thus the blood pH raises.

Last Answer : How does the breathing process correct alkalosis?

Description : Acidosis is the condition in which the blood pH is abnormally low. Alkalosis is the condition in which the blood pH is abnormally high. Normal pH levels for the human blood are between 7.35 and 7.45 - slightly alkaline.

Last Answer : How does the breathing process correct acidosis?

Description : A shift in the oxygen-haemoglobin dissociation curve to the right occurs in : a. hypothermia b. carboxyhaemoglobin c. acidosis d. fetal haemoglobin

Last Answer : acidosis