Draw a well labelled diagram of ‘Soxhlet apparatus.’ Mention the various limitations of continuous hot percolation process.

Draw a well labelled diagram of ‘Soxhlet apparatus.’ Mention the various limitations of continuous hot percolation process. 
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Answer :

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Limitation:

1. Physical character of the drug: If the drug would block the soxhlet apparatus then this process cannot be used for extraction. Eg opium. Gum, resin, orange peel, etc.

2. Solvent: Only pure solvents or constant boiling mixtures can be used.

3. Chemical constituents of the drug: The process is unsuitable for drugs having thermolabile active constituents such as enzymes, alkaloids, anthraquinone derivatives, esters, etc. 

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