State and explain the stages of simple Percolation

State and explain the stages of simple Percolation
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1 Answer

Answer :

Stages of Percolation:-

a) Imbibition

b) Maceration

c) Percolation

a) Imbibition :-  

1) Powders drug is moistened with a sufficient quantity of menstruum & allowed to stand for 4 hrs in a closed vessel.

2) Pack the moistened drugs into a percolator & add sufficient quantity of menstruum to saturate the material.

3) When liquid starts coming out from the outlet of percolator, te outlet is closed. Them sufficient quantity of menstruum is added in order to leave a layer above the drug.

b) Maceration :-  

1) The moistened drug is left in contact with menstruum for 24 hours.

2) During this period, the menstruum dissolves the active constituents of the drug & becomes almost saturated with it.

c) Percolation :-  

It consist of the downward displacement of the saturated solution formed in maceration and extraction of the remaining active constituents present in the drug by the slow passage of the menstruum through the column of the drug.
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