Description : Cervical priming with prostaglandin results in (a) Facilitation of sperm movement through cervical canal (b) Increased cervical tone (c) Softening of cervix (d) Increased cervical secretions
Last Answer : Ans: C
Description : The following drug is used for cervical priming to facilitate labour: A. Oxytocin B. Clomiphene C. Progesterone D. Prostaglandin E2
Last Answer : D. Prostaglandin E2
Description : Choose the correct statement about latanoprost: A. It is a PGF2α derivative used in glaucoma B. It is a selective α1 blocker used in benign hypertrophy of prostate C. It is a 5-α- ... reduce the size of enlarged prostate gland D. It is a PGE2 analogue used intravaginally for cervical priming
Last Answer : A. It is a PGF2α derivative used in glaucoma
Description : Morphine induced constipation involves the following mechanisms except: A. Increase in tone and decrease in propulsive activity of intestinal muscles B. Antivagal action C. Spasm of gastrointestinal sphincters D. Reduction of gastrointestinal secretions
Last Answer : B. Antivagal action
Description : The primary mechanism of action of the combined estrogen-progestin oral contraceptive pill is: A. Production of cervical mucus hostile to sperm penetration B. Suppression of FSH and ... Making endometrium unsuitable for implantation D. Enhancing uterine contractions to dislodge the fertilized ovum
Last Answer : B. Suppression of FSH and LH release
Description : The term cervical cancer is about the cervix, but cervical muscles is about the neck/spine?
Last Answer : Cervix is Latin for neck Places where it gets narrow is called the neck- Narrow part of uterus is the neck Cervix means neck Cervical means pertaining to the neck
Description : The following action(s) of heparin is/are essential for inhibition of factor Xa: A. Facilitation of antithrombin III mediated inhibition of factor XIIa B. Provision of scaffold for the clotting factor ... configurational change in antithrombin III to expose its interacting sites D. Both A' and B
Last Answer : C. Induction of a configurational change in antithrombin III to expose its interacting sites
Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa
Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi
Description : The antidotal effect of sodium nitrite in cyanide poisoning is dependent upon: A. Chemical combination of sodium nitrite with cyanide B. Vasodilatation caused by sodium nitrite C. ... haemoglobin to methaemoglobin by sodium nitrite D. Facilitation of cyanocobalamine formation by sodium nitrite
Last Answer : C. Conversion of haemoglobin to methaemoglobin by sodium nitrite
Description : The primary action by which entacapone and tolcapone enhance the therapeutic effect of levodopa-carbidopa in parkinsonism is: A. Inhibition of levodopa methylation in the liver B. Inhibition of ... of dopamine in the brain D. Facilitation of active transport of levodopa across brain capillaries
Last Answer : A. Inhibition of levodopa methylation in the liver
Description : The most probable mechanism of anticonvulsant action of phenytoin is: A. Facilitation of GABAergic inhibitory transmission B. Hyperpolarization of neurones C. Interaction with Ca2+ channels to promote Ca2+ influx D. Prolongation of voltage sensitive neuronal Na+ channel inactivation
Last Answer : D. Prolongation of voltage sensitive neuronal Na+ channel inactivation
Description : The primary mechanism of action of benzodiazepines is: A. Dopamine antagonism B. Adenosine antagonism C. Opening of neuronal chloride channels D. Facilitation of GABA-mediated chloride influx
Last Answer : D. Facilitation of GABA-mediated chloride influx
Description : Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue
Last Answer : . Facilitation of neoglucogenesis by liver
Description : Presence of H2S in raw water (to be chlorinated) results in the (A) Reduced softening capacity of zeolite (B) Increased dosage of chlorine to provide a disinfecting residual in the water (C) Easy removal of its hardness (D) None of these
Last Answer : (B) Increased dosage of chlorine to provide a disinfecting residual in the water
Description : What happens during fertilisation in humans after many sperms reach close to the ovum? (a) Secretions of acrosome helps one sperm enter cytoplasm of ovum through zona pellucida. (b) All sperms except ... all the sperms except one. (d) Only two sperms nearest the ovum penetrate zona pellucida.
Last Answer : (a) Secretions of acrosome helps one sperm enter cytoplasm of ovum through zona pellucida.
Description : The following eicosanoid is generated through the lipoxygenase pathway: A. Prostaglandin E2 B. Thromboxane A2 C. Leukotriene C4 D. Prostacyclin
Last Answer : C. Leukotriene C4
Description : The mechanisms involved in the causation of dangerous cardiac arrhythmias due to overdose of tricyclic antidepressants include the following except: A. Intraventricular conduction block B. Potentiation of noradrenaline C. Antagonism of acetylcholine D. Increased vagal tone
Last Answer : D. Increased vagal tone
Description : The usual cardiovascular effect of levodopa is: A. Bradycardia due to increased vagal tone B. Rise in blood pressure due to increased noradrenaline content of adrenergic nerve endings C. Fall in blood pressure due to decrease in sympathetic tone D. Both ‘A’ and ‘B’ are correct
Last Answer : C. Fall in blood pressure due to decrease in sympathetic tone
Description : Estrogens are palliative in the following malignancy: A. Carcinoma breast B. Carcinoma cervix C. Endometrial carcinoma D. Carcinoma prostate
Last Answer : D. Carcinoma prostate
Description : Assertion : The acrosomal secretions of sperm , help it in entering in the cytoplasm of the ovum . Reason : It contains sperm lysin .
Last Answer : Assertion : The acrosomal secretions of sperm , help it in entering in the cytoplasm of the ovum . ... . D. If both Assertion & Reason are False.
Description : What are Secretions of glands combined with sperm?
Last Answer : Semen
Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion
Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions
Description : Ventricular remodeling after myocardial infarction involves the mediation of: A. Angiotensin II B. Prostaglandin C. Bradykinin D. Thromboxane A2
Last Answer : A. Angiotensin II
Description : Select the drug that has been used to suppress labour: A. Atropine B. Ritodrine C. Prostaglandin E2 D. Progesterone
Last Answer : B. Ritodrine
Description : The drug of choice for controlling postpartum haemorrhage is: A. Oxytocin B. Methylergometrine C. Dihydroergotamine D. Prostaglandin E2
Last Answer : B. Methylergometrine
Description : Aldosterone enhances Na+ reabsorption in renal tubules by: A. Stimulating carbonic anhydrase B. Activating Na+ K+ ATPase C. Inducing the synthesis of Na+ K+ ATPase D. Inducing renal prostaglandin synthesis
Last Answer : C. Inducing the synthesis of Na+ K+ ATPase
Description : Currently, the first choice drug for open angle glaucoma is: A. Miotic eye drops B. Ocular α2 adrenergic agonists C. Ocular prostaglandin analogues D. Ocular β adrenergic blockers
Last Answer : D. Ocular β adrenergic blockers
Description : Select the receptor that is located intracellularly: A. Opioid μ receptor B. Steroid receptor C. Prostaglandin receptor D. Angiotensin receptor
Last Answer : B. Steroid receptor
Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor
Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis
Description : The distinctive feature of nimesulide is: A. It does not inhibit prostaglandin synthesis B. It does not cause gastric irritation C. It is usually well tolerated by aspirin intolerant asthma patients D. It is not bound to plasma proteins
Last Answer : C. It is usually well tolerated by aspirin intolerant asthma patients
Description : Choose the correct statement about nonopioid analgesics: A. All have antiinflammatory property B. All lack dependence producing liability C. All act exclusively at peripheral pain mechanisms D. All inhibit prostaglandin synthesis
Last Answer : B. All lack dependence producing liability
Description : The early pregnancy uterus is sensitive to the following oxytocic: A. Oxytocin B. Methylergometrine C. Prostaglandin F2α D. Both ‘A’ and ‘B’ are correct
Last Answer : C. Prostaglandin F2α
Description : Tachyphylaxis to many actions on repeated injection is a feature of the following autacoid: A. Histamine B. 5-Hydroxytryptamine C. Bradykinin D. Prostaglandin E2
Last Answer : B. 5-Hydroxytryptamine
Description : Use of glycopyrrolate in preanaesthetic medication serves the following purposes except: A. Prevents respiratory secretions during anaesthesia B. Guards against reflex vagal bradycardia during ... Produces amnesia for perioperative events D. Reduces the probability of occurrence of laryngospasm
Last Answer : C. Produces amnesia for perioperative events
Description : Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects
Last Answer : C. It has faster onset of bronchodilator action than inhaled salbutamol
Description : A 17-year-old patient involved in an automobile accident is paralyzed with multiple peripheral extremity injuries. Nutritional support is instituted with a transnasal feeding catheter. Which of the ... pylorus into the first portion of the duodenum reduces the risk of regurgitation and aspiration
Last Answer : Answer: a, c, d The use of transnasal feeding catheters for intragastric feeding or for duodenal intubation are popular adjuncts for providing nutritional support by the enteral route. The ... the fourth portion of the duodenum reduces the risk of regurgitation and aspiration of feeding formulas
Description : A progestin and an estrogen are combined in oral contraceptive pill because: A. The estrogen blocks the side effects of the progestin B. The progestin blocks the side effects of the estrogen C. Both synergise to suppress ovulation D. Both synergise to produce hostile cervical mucus
Last Answer : C. Both synergise to suppress ovulation
Description : Select the drug which administered orally causes cervical ripening in pregnant women to facilitate surgical abortion or induction of labour: A. Mifepristone B. Raloxifene C. Natural progesterone D. Levonorgestre
Last Answer : A. Mifepristone
Description : Progesterone administration: A. Suppresses onset of menstruation B. Induces watery cervical secretion C. Sensitizes the uterus to oxytocin D. Cornifies vaginal epithelium
Last Answer : A. Suppresses onset of menstruation
Description : Choose the selective estrogen receptor modulator that is useful in dysfunctional uterine bleeding by acting as estrogen antagonist in endometrium, but does not alter vaginal epithelium or cervical mucus: A. Ormeloxifene B. Tamoxifen C. Centchroman D. Danazol
Last Answer : . Ormeloxifen
Description : Microsomal enzyme induction has one of the following features: A. Takes about one week to develop B. Results in increased affinity of the enzyme for the substrate C. It is irreversible D. Can be used to treat acute drug poisonings
Last Answer : A. Takes about one week to develop
Description : Priming in a distillation column (A) Results from very low gas velocity (B) Is desirable from point efficiency consideration (C) Is characterised by the presence of foam throughout the space between trays (D) Reduces the overall pressure drop
Last Answer : (C) Is characterised by the presence of foam throughout the space between trays
Description : The technique called Gamete Intra Fallopian Transfer (GIFT) is recommended for those females (a) who cannot produce an ovum (b) who cannot retain the fetus inside uterus (c) whose cervical ... narrow to allow passage for the sperms (d) who cannot provide suitable environment for fertilisation.
Last Answer : (a) who cannot produce an ovum
Description : 3. In IVF technique zygote or early embryo is transferred into a. Cervical canal b. Uterus c. Fallopian tube d. Vagina
Last Answer : c. Fallopian tube
Description : The following is true of loperamide except: A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action B. It acts on the opioid receptors in the gut C. It increases ... of the intestines D. It inhibits intestinal secretion by binding to calmodulin in the mucosal cells
Last Answer : A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action
Description : Select the drug(s) which afford(s) relief in gastroesophageal reflux by increasing lower esophageal sphincter tone and promoting gastric emptying, but without affecting acidity of gastric contents: A. Sodium alginate B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C
Last Answer : D. Both ‘B’ and ‘C’
Description : ndicate the drug which does not improve lower esophageal sphincter tone or prevent gastroesophageal reflux, but is used as first line treatment of gastroesophageal reflux disease: A. Sodium alginate + aluminium hydroxide gel B. Omeprazole C. Mosapride D. Famotidine
Last Answer : B. Omeprazole
Description : Metoclopramide has the following actions except: A. Increases lower esophageal sphincter tone B. Increases tone of pyloric sphincter C. Increases gastric peristalsis D. Increases intestinal peristalsis
Last Answer : B. Increases tone of pyloric sphincter